Direct estimates of natural selection in iberia indicate calcium absorption was not the only driver of lactase persistence in Europe

Molecular Biology and Evolution

Volumn 31, Issue 4, 2014, Pages 975-983

  Sverrisdóttir, Oddný Ósk ^a   Timpson, Adrian ^b   Toombs, Jamie ^c   Lecoeur, Cecile ^d,e   Froguel, Philippe ^d,e,f   Carretero, Jose Miguel ^g   Arsuaga Ferreras, Juan Luis ^h   Götherström, Anders ^a,i   Thomas, Mark G ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d France   (France)

^e CNRS UMR8199   (France)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

^g UNIVERSITY OF BURGOS   (Spain)

^h UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

ⁱ STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Ancient DNA; Forward simulation; Iberia; Lactase persistence; Natural selection; Neolithic

Indexed keywords

CALCIUM; LACTASE; MITOCHONDRIAL DNA; VITAMIN D;

ARTICLE; CALCIUM ABSORPTION; CONTROLLED STUDY; EUROPE; FEMALE; FOOD INTAKE; GENE FREQUENCY; GENETIC DRIFT; HUMAN; HUMAN TISSUE; MALE; MILK; NATURAL SELECTION; NEOLITHIC; POLYMERASE CHAIN REACTION; POPULATION SIZE; PYROSEQUENCING; SINGLE NUCLEOTIDE POLYMORPHISM; SKELETON; ULTRAVIOLET B RADIATION;

ANCIENT DNA; FORWARD SIMULATION; IBERIA; LACTASE PERSISTENCE; NATURAL SELECTION; NEOLITHIC;

CALCIUM; DNA, MITOCHONDRIAL; EVOLUTION, MOLECULAR; FEMALE; FRANCE; GENE FREQUENCY; GENETIC DRIFT; HUMANS; INTESTINAL ABSORPTION; LACTASE; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA; SPAIN;

EID: 84897886975     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msu049     Document Type: Article

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