PEP-1-PEA-15 protects against toxin-induced neuronal damage in a mouse model of Parkinson's disease

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 6, 2014, Pages 1686-1700

  Ahn, Eun Hee ^a   Kim, Dae Won ^b   Shin, Min Jea ^a   Kim, Hye Ri ^a   Kim, So Mi ^a   Woo, Su Jung ^a   Eom, Seon Ae ^a   Jo, Hyo Sang ^a   Kim, Duk Soo ^c   Cho, Sung Woo ^d   Park, Jinseu ^a   Eum, Won Sik ^a   Choi, Soo Young ^a  

^a Hallym University   (South Korea)

^b Gangneung Wonju National University   (South Korea)

^c Soonchunhyang University   (South Korea)

^d University of Ulsan College of Medicine   (South Korea)

Author keywords

Neurotoxin; Oxidative stress; Parkinson's disease; PEP 1 Phosphoprotein enriched in astrocytes 15; Protein therapy

Indexed keywords

ANTIPARKINSON AGENT; CASPASE 3; DOPAMINE; JANUS KINASE; NEUROMODULIN; PEP 1 PEA 15 PROTEIN; PHOSPHOPROTEIN; PHOSPHOPROTEIN ENRICHED IN ASTROCYTES 15; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; UNCLASSIFIED DRUG; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; PEP 1 PHOSPHOPROTEIN ENRICHED IN ASTROCYTE 15; REACTIVE OXYGEN METABOLITE;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CELL DAMAGE; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CORPUS STRIATUM; DEGENERATIVE DISEASE; DNA FRAGMENTATION; DOPAMINERGIC NERVE CELL; DRUG CYTOTOXICITY; DRUG PURIFICATION; EXPRESSION VECTOR; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; MOUSE; NERVE CELL; NEUROBLASTOMA CELL; NEUROPROTECTION; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; WESTERN BLOTTING; ANIMAL TISSUE; BEHAVIOR DISORDER; DRUG MECHANISM; DRUG TRANSPORT; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL NECROSIS; NERVE INJURY;

NEUROTOXIN; OXIDATIVE STRESS; PARKINSON'S DISEASE; PEP-1-PHOSPHOPROTEIN ENRICHED IN ASTROCYTES 15; PROTEIN THERAPY;

ANIMALS; CYSTEAMINE; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; PARKINSON DISEASE; PEPTIDES; PHOSPHOPROTEINS; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; TRANSDUCTION, GENETIC;

EID: 84897873665     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2014.01.004     Document Type: Article

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