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Volumn 81, Issue , 2014, Pages 311-317

Altered cerebral vascular volumes and solute transport at the blood-brain barriers of two transgenic mouse models of Alzheimer's disease

Author keywords

3xTg AD; Alzheimer's disease; APP PS1; Blood brain barrier integrity; Brain vascular volume; In situ brain perfusion

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; DIAZEPAM; GLUCOSE; GLUCOSE TRANSPORTER 1; PRESENILIN 1; TAU PROTEIN; TRITIUM; PSEN1 PROTEIN, HUMAN; SLC2A1 PROTEIN, MOUSE; SUCROSE;

EID: 84897829598     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.02.010     Document Type: Article
Times cited : (60)

References (53)
  • 1
    • 84891778255 scopus 로고    scopus 로고
    • Brain uptake of a fluorescent vector targeting the transferrin receptor: A novel application of in situ brain perfusion
    • W. Alata, S. Paris-Robidas, V. Emond, F. Bourasset, and F. Calon Brain uptake of a fluorescent vector targeting the transferrin receptor: a novel application of in situ brain perfusion Mol. Pharm. 11 2014 243 253
    • (2014) Mol. Pharm. , vol.11 , pp. 243-253
    • Alata, W.1    Paris-Robidas, S.2    Emond, V.3    Bourasset, F.4    Calon, F.5
  • 2
    • 67349142021 scopus 로고    scopus 로고
    • Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
    • R.D. Bell, and B.V. Zlokovic Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease Acta Neuropathol. 118 2009 103 113
    • (2009) Acta Neuropathol. , vol.118 , pp. 103-113
    • Bell, R.D.1    Zlokovic, B.V.2
  • 4
    • 34249040510 scopus 로고    scopus 로고
    • Blood-brain barrier impairment in Alzheimer disease: Stability and functional significance
    • G.L. Bowman, J.A. Kaye, M. Moore, D. Waichunas, N.E. Carlson, and J.F. Quinn Blood-brain barrier impairment in Alzheimer disease: stability and functional significance Neurology 68 2007 1809 1814
    • (2007) Neurology , vol.68 , pp. 1809-1814
    • Bowman, G.L.1    Kaye, J.A.2    Moore, M.3    Waichunas, D.4    Carlson, N.E.5    Quinn, J.F.6
  • 5
    • 0034021375 scopus 로고    scopus 로고
    • Vascular involvement in cognitive decline and dementia. Epidemiologic evidence from the Rotterdam Study and the Rotterdam Scan Study
    • M.M. Breteler Vascular involvement in cognitive decline and dementia. Epidemiologic evidence from the Rotterdam Study and the Rotterdam Scan Study Ann. N. Y. Acad. Sci. 903 2000 457 465
    • (2000) Ann. N. Y. Acad. Sci. , vol.903 , pp. 457-465
    • Breteler, M.M.1
  • 6
    • 0036632540 scopus 로고    scopus 로고
    • Magnetic resonance imaging in dementia. A study of brain white matter changes
    • L. Bronge Magnetic resonance imaging in dementia. A study of brain white matter changes Acta Radiol. Suppl. 2002 1 32
    • (2002) Acta Radiol. Suppl. , pp. 1-32
    • Bronge, L.1
  • 8
    • 84865822723 scopus 로고    scopus 로고
    • Hypertension induces brain beta-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature
    • D. Carnevale, G. Mascio, I. D'Andrea, V. Fardella, R.D. Bell, I. Branchi, F. Pallante, B. Zlokovic, S.S. Yan, and G. Lembo Hypertension induces brain beta-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature Hypertension 60 2012 188 197
    • (2012) Hypertension , vol.60 , pp. 188-197
    • Carnevale, D.1    Mascio, G.2    D'Andrea, I.3    Fardella, V.4    Bell, R.D.5    Branchi, I.6    Pallante, F.7    Zlokovic, B.8    Yan, S.S.9    Lembo, G.10
  • 9
    • 0037156419 scopus 로고    scopus 로고
    • Immunohistochemical localization and quantification of glucose transporters in the mouse brain
    • C. Choeiri, W. Staines, and C. Messier Immunohistochemical localization and quantification of glucose transporters in the mouse brain Neuroscience 111 2002 19 34
    • (2002) Neuroscience , vol.111 , pp. 19-34
    • Choeiri, C.1    Staines, W.2    Messier, C.3
  • 10
    • 0033975029 scopus 로고    scopus 로고
    • Development of an in situ mouse brain perfusion model and its application to mdr1a P-glycoprotein-deficient mice
    • C. Dagenais, C. Rousselle, G.M. Pollack, and J.M. Scherrmann Development of an in situ mouse brain perfusion model and its application to mdr1a P-glycoprotein-deficient mice J. Cereb. Blood Flow Metab. 20 2000 381 386
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 381-386
    • Dagenais, C.1    Rousselle, C.2    Pollack, G.M.3    Scherrmann, J.M.4
  • 11
    • 1242331823 scopus 로고    scopus 로고
    • Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics
    • J.C. de la Torre Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics Lancet Neurol. 3 2004 184 190
    • (2004) Lancet Neurol. , vol.3 , pp. 184-190
    • De La Torre, J.C.1
  • 12
    • 84893200583 scopus 로고    scopus 로고
    • Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: Implication for bioenergetic intervention
    • F. Ding, J. Yao, J.R. Rettberg, S. Chen, and R.D. Brinton Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention PLoS One 8 2013 e79977
    • (2013) PLoS One , vol.8 , pp. 79977
    • Ding, F.1    Yao, J.2    Rettberg, J.R.3    Chen, S.4    Brinton, R.D.5
  • 15
    • 84867722515 scopus 로고    scopus 로고
    • Amyloid-beta-dependent compromise of microvascular structure and function in a model of Alzheimer's disease
    • A. Dorr, B. Sahota, L.V. Chinta, M.E. Brown, A.Y. Lai, K. Ma, C.A. Hawkes, J. McLaurin, and B. Stefanovic Amyloid-beta-dependent compromise of microvascular structure and function in a model of Alzheimer's disease Brain 135 2012 3039 3050
    • (2012) Brain , vol.135 , pp. 3039-3050
    • Dorr, A.1    Sahota, B.2    Chinta, L.V.3    Brown, M.E.4    Lai, A.Y.5    Ma, K.6    Hawkes, C.A.7    McLaurin, J.8    Stefanovic, B.9
  • 16
    • 76649137234 scopus 로고    scopus 로고
    • Detection of vascular alterations by in vivo magnetic resonance angiography and histology in APP/PS1 mouse model of Alzheimer's disease
    • T. El Tayara Nel, B. Delatour, A. Volk, and M. Dhenain Detection of vascular alterations by in vivo magnetic resonance angiography and histology in APP/PS1 mouse model of Alzheimer's disease MAGMA 23 2010 53 64
    • (2010) MAGMA , vol.23 , pp. 53-64
    • El Tayara Nel, T.1    Delatour, B.2    Volk, A.3    Dhenain, M.4
  • 19
    • 33646002650 scopus 로고    scopus 로고
    • Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation
    • C.X. Gong, F. Liu, I. Grundke-Iqbal, and K. Iqbal Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation J. Alzheimers Dis. 9 2006 1 12
    • (2006) J. Alzheimers Dis. , vol.9 , pp. 1-12
    • Gong, C.X.1    Liu, F.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 21
    • 35348903108 scopus 로고    scopus 로고
    • Pathophysiology of the blood-brain barrier: Animal models and methods
    • B.T. Hawkins, and R.D. Egleton Pathophysiology of the blood-brain barrier: animal models and methods Curr. Top. Dev. Biol. 80 2008 277 309
    • (2008) Curr. Top. Dev. Biol. , vol.80 , pp. 277-309
    • Hawkins, B.T.1    Egleton, R.D.2
  • 23
    • 35748935872 scopus 로고    scopus 로고
    • Amyloid beta deposition is related to decreased glucose transporter-1 levels and hippocampal atrophy in brains of aged APP/PS1 mice
    • C.R. Hooijmans, C. Graven, P.J. Dederen, H. Tanila, T. van Groen, and A.J. Kiliaan Amyloid beta deposition is related to decreased glucose transporter-1 levels and hippocampal atrophy in brains of aged APP/PS1 mice Brain Res. 1181 2007 93 103
    • (2007) Brain Res. , vol.1181 , pp. 93-103
    • Hooijmans, C.R.1    Graven, C.2    Dederen, P.J.3    Tanila, H.4    Van Groen, T.5    Kiliaan, A.J.6
  • 24
    • 0347654897 scopus 로고    scopus 로고
    • Causes and consequences of disturbances of cerebral glucose metabolism in sporadic Alzheimer disease: Therapeutic implications
    • S. Hoyer Causes and consequences of disturbances of cerebral glucose metabolism in sporadic Alzheimer disease: therapeutic implications Adv. Exp. Med. Biol. 541 2004 135 152
    • (2004) Adv. Exp. Med. Biol. , vol.541 , pp. 135-152
    • Hoyer, S.1
  • 28
    • 0036130159 scopus 로고    scopus 로고
    • Small vessel disease and Alzheimer's dementia: Pathological considerations
    • R.N. Kalaria Small vessel disease and Alzheimer's dementia: pathological considerations Cerebrovasc. Dis. 13 Suppl. 2 2002 48 52
    • (2002) Cerebrovasc. Dis. , vol.13 , Issue.SUPPL. 2 , pp. 48-52
    • Kalaria, R.N.1
  • 29
    • 0024419325 scopus 로고
    • Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer disease
    • R.N. Kalaria, and S.I. Harik Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer disease J. Neurochem. 53 1989 1083 1088
    • (1989) J. Neurochem. , vol.53 , pp. 1083-1088
    • Kalaria, R.N.1    Harik, S.I.2
  • 30
    • 34047276804 scopus 로고    scopus 로고
    • Capillary beds are decreased in Alzheimer's disease, but not in Binswanger's disease
    • H. Kitaguchi, M. Ihara, H. Saiki, R. Takahashi, and H. Tomimoto Capillary beds are decreased in Alzheimer's disease, but not in Binswanger's disease Neurosci. Lett. 417 2007 128 131
    • (2007) Neurosci. Lett. , vol.417 , pp. 128-131
    • Kitaguchi, H.1    Ihara, M.2    Saiki, H.3    Takahashi, R.4    Tomimoto, H.5
  • 31
    • 74949115348 scopus 로고    scopus 로고
    • Human truncated tau is using a different mechanism from amyloid-beta to damage the blood-brain barrier
    • A. Kovac, M. Zilkova, M.A. Deli, N. Zilka, and M. Novak Human truncated tau is using a different mechanism from amyloid-beta to damage the blood-brain barrier J. Alzheimers Dis. 18 2009 897 906
    • (2009) J. Alzheimers Dis. , vol.18 , pp. 897-906
    • Kovac, A.1    Zilkova, M.2    Deli, M.A.3    Zilka, N.4    Novak, M.5
  • 32
    • 20344371724 scopus 로고    scopus 로고
    • Stereological analysis of microvascular parameters in a double transgenic model of Alzheimer's disease
    • G.D. Lee, J.H. Aruna, P.M. Barrett, D.L. Lei, D.K. Ingram, and P.R. Mouton Stereological analysis of microvascular parameters in a double transgenic model of Alzheimer's disease Brain Res. Bull. 65 2005 317 322
    • (2005) Brain Res. Bull. , vol.65 , pp. 317-322
    • Lee, G.D.1    Aruna, J.H.2    Barrett, P.M.3    Lei, D.L.4    Ingram, D.K.5    Mouton, P.R.6
  • 33
    • 38049050725 scopus 로고    scopus 로고
    • Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
    • Y. Liu, F. Liu, K. Iqbal, I. Grundke-Iqbal, and C.X. Gong Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease FEBS Lett. 582 2008 359 364
    • (2008) FEBS Lett. , vol.582 , pp. 359-364
    • Liu, Y.1    Liu, F.2    Iqbal, K.3    Grundke-Iqbal, I.4    Gong, C.X.5
  • 34
    • 84858332587 scopus 로고    scopus 로고
    • Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: Limitations as a translatable model of Alzheimer's disease
    • F. Luo, N.R. Rustay, U. Ebert, V.P. Hradil, T.B. Cole, D.A. Llano, S.R. Mudd, Y. Zhang, G.B. Fox, and M. Day Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease Neurobiol. Aging 33 2010 933 944
    • (2010) Neurobiol. Aging , vol.33 , pp. 933-944
    • Luo, F.1    Rustay, N.R.2    Ebert, U.3    Hradil, V.P.4    Cole, T.B.5    Llano, D.A.6    Mudd, S.R.7    Zhang, Y.8    Fox, G.B.9    Day, M.10
  • 36
    • 80054711185 scopus 로고    scopus 로고
    • Vascular beta-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAbeta mice
    • M. Merlini, E.P. Meyer, A. Ulmann-Schuler, and R.M. Nitsch Vascular beta-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAbeta mice Acta Neuropathol. 122 2011 293 311
    • (2011) Acta Neuropathol. , vol.122 , pp. 293-311
    • Merlini, M.1    Meyer, E.P.2    Ulmann-Schuler, A.3    Nitsch, R.M.4
  • 38
    • 78650225540 scopus 로고    scopus 로고
    • Intact memory in TGF-beta1 transgenic mice featuring chronic cerebrovascular deficit: Recovery with pioglitazone
    • N. Nicolakakis, T. Aboulkassim, A. Aliaga, X.K. Tong, P. Rosa-Neto, and E. Hamel Intact memory in TGF-beta1 transgenic mice featuring chronic cerebrovascular deficit: recovery with pioglitazone J. Cereb. Blood Flow Metab. 31 2011 200 211
    • (2011) J. Cereb. Blood Flow Metab. , vol.31 , pp. 200-211
    • Nicolakakis, N.1    Aboulkassim, T.2    Aliaga, A.3    Tong, X.K.4    Rosa-Neto, P.5    Hamel, E.6
  • 40
    • 78650206599 scopus 로고    scopus 로고
    • Transgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's disease
    • B. Ongali, N. Nicolakakis, C. Lecrux, T. Aboulkassim, P. Rosa-Neto, P. Papadopoulos, X.K. Tong, and E. Hamel Transgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's disease Am. J. Pathol. 177 2010 3071 3080
    • (2010) Am. J. Pathol. , vol.177 , pp. 3071-3080
    • Ongali, B.1    Nicolakakis, N.2    Lecrux, C.3    Aboulkassim, T.4    Rosa-Neto, P.5    Papadopoulos, P.6    Tong, X.K.7    Hamel, E.8
  • 41
    • 0034870813 scopus 로고    scopus 로고
    • Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease
    • J.F. Poduslo, G.L. Curran, T.M. Wengenack, B. Malester, and K. Duff Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease Neurobiol. Dis. 8 2001 555 567
    • (2001) Neurobiol. Dis. , vol.8 , pp. 555-567
    • Poduslo, J.F.1    Curran, G.L.2    Wengenack, T.M.3    Malester, B.4    Duff, K.5
  • 42
    • 27544434764 scopus 로고    scopus 로고
    • Glucose transport to the brain: A systems model
    • A.A. Qutub, and C.A. Hunt Glucose transport to the brain: a systems model Brain Res. Brain Res. Rev. 49 2005 595 617
    • (2005) Brain Res. Brain Res. Rev. , vol.49 , pp. 595-617
    • Qutub, A.A.1    Hunt, C.A.2
  • 43
    • 80052404569 scopus 로고    scopus 로고
    • Impaired hypoxic response in senescent mouse brain
    • T. Rabie, R. Kunze, and H.H. Marti Impaired hypoxic response in senescent mouse brain Int. J. Dev. Neurosci. 29 2011 655 661
    • (2011) Int. J. Dev. Neurosci. , vol.29 , pp. 655-661
    • Rabie, T.1    Kunze, R.2    Marti, H.H.3
  • 44
    • 84865080225 scopus 로고    scopus 로고
    • Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer's disease
    • A. Rancillac, H. Geoffroy, and J. Rossier Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer's disease Curr. Alzheimer Res. 9 2012 1221 1230
    • (2012) Curr. Alzheimer Res. , vol.9 , pp. 1221-1230
    • Rancillac, A.1    Geoffroy, H.2    Rossier, J.3
  • 46
    • 0035131601 scopus 로고    scopus 로고
    • Age-related changes of glutathione content, glucose transport and metabolism, and mitochondrial electron transfer function in mouse brain
    • T. Sasaki, M. Senda, S. Kim, S. Kojima, and A. Kubodera Age-related changes of glutathione content, glucose transport and metabolism, and mitochondrial electron transfer function in mouse brain Nucl. Med. Biol. 28 2001 25 31
    • (2001) Nucl. Med. Biol. , vol.28 , pp. 25-31
    • Sasaki, T.1    Senda, M.2    Kim, S.3    Kojima, S.4    Kubodera, A.5
  • 47
    • 0028241915 scopus 로고
    • Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease
    • I.A. Simpson, K.R. Chundu, T. Davies-Hill, W.G. Honer, and P. Davies Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease Ann. Neurol. 35 1994 546 551
    • (1994) Ann. Neurol. , vol.35 , pp. 546-551
    • Simpson, I.A.1    Chundu, K.R.2    Davies-Hill, T.3    Honer, W.G.4    Davies, P.5
  • 48
    • 61349102361 scopus 로고    scopus 로고
    • Blood-brain barrier permeability in Alzheimer's disease: A case-control MRI study
    • J.M. Starr, A.J. Farrall, P. Armitage, B. McGurn, and J. Wardlaw Blood-brain barrier permeability in Alzheimer's disease: a case-control MRI study Psychiatry Res. 171 2009 232 241
    • (2009) Psychiatry Res. , vol.171 , pp. 232-241
    • Starr, J.M.1    Farrall, A.J.2    Armitage, P.3    McGurn, B.4    Wardlaw, J.5
  • 49
    • 3442894794 scopus 로고    scopus 로고
    • Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model
    • M. Ujiie, D.L. Dickstein, D.A. Carlow, and W.A. Jefferies Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model Microcirculation 10 2003 463 470
    • (2003) Microcirculation , vol.10 , pp. 463-470
    • Ujiie, M.1    Dickstein, D.L.2    Carlow, D.A.3    Jefferies, W.A.4
  • 50
    • 41649097332 scopus 로고    scopus 로고
    • FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice
    • J. Valla, F. Gonzalez-Lima, and E.M. Reiman FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice Int. J. Dev. Neurosci. 26 2008 253 258
    • (2008) Int. J. Dev. Neurosci. , vol.26 , pp. 253-258
    • Valla, J.1    Gonzalez-Lima, F.2    Reiman, E.M.3
  • 51
    • 0034095539 scopus 로고    scopus 로고
    • Contrast-enhanced MRI of white matter lesions in patients with blood-brain barrier dysfunction
    • L.O. Wahlund, and L. Bronge Contrast-enhanced MRI of white matter lesions in patients with blood-brain barrier dysfunction Ann. N. Y. Acad. Sci. 903 2000 477 481
    • (2000) Ann. N. Y. Acad. Sci. , vol.903 , pp. 477-481
    • Wahlund, L.O.1    Bronge, L.2
  • 53
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
    • B.V. Zlokovic Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders Nat. Rev. Neurosci. 12 2011 723 738
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 723-738
    • Zlokovic, B.V.1


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