Human leukocyte antigen genes and interferon beta preparations influence risk of developing neutralizing anti-drug antibodies in multiple sclerosis

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Link, Jenny ^a   Ryner, Malin Lundkvist ^a   Fink, Katharina ^a   Hermanrud, Christina ^a   Lima, Izaura ^a   Brynedal, Boel ^a   Kockum, Ingrid ^a   Hillert, Jan ^a   Fogdell Hahn, Anna ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; BETA1 INTERFERON; HLA ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; INTERFERON BETA SERINE; NEUTRALIZING ANTIBODY; HLA DQ ANTIGEN; HLA DRB1 ANTIGEN; HLA-DQA1 ANTIGEN; HLA-DRB1*04 ANTIGEN;

ADULT; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; BINDING AFFINITY; BINDING SITE; COHORT ANALYSIS; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; DRUG RESPONSE; FEMALE; GENE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HLA ANTIGEN CLASS 1 GENE; HLA ANTIGEN CLASS 2 GENE; HUMAN; HUMAN LEUKOCYTE ANTIGEN GENE; MALE; MIDDLE AGED; MOLECULAR DYNAMICS; MULTIPLE SCLEROSIS; PREDICTION; RISK ASSESSMENT; RISK FACTOR; GENETICS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ADULT; ANTIBODIES, NEUTRALIZING; FEMALE; GENES, MHC CLASS II; HLA ANTIGENS; HLA-DQ ALPHA-CHAINS; HLA-DRB1 CHAINS; HUMANS; INTERFERON-BETA; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS;

EID: 84897568057     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090479     Document Type: Article

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