IL-21 receptor expression in human tendinopathy

Mediators of Inflammation

Volumn 2014, Issue , 2014, Pages

  Campbell, Abigail L ^a,b   Smith, Nicola C ^a   Reilly, James H ^a   Kerr, Shauna C ^a   Leach, William J ^c   Fazzi, Umberto G ^c   Rooney, Brian P ^c   Murrell, George A C ^d   Millar, Neal L ^a,c  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^c WESTERN INFIRMARY   (United Kingdom)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE MARKER; COLLAGEN FIBRIL; DECAY ACCELERATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 21; INTERLEUKIN 21 RECEPTOR; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MACROPHAGE; MALE; METAPLASIA; MUSCLE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TENDINITIS; TENOCYTE; UPREGULATION; ADOLESCENT; CELL CULTURE; COHORT ANALYSIS; CYTOLOGY; GENE EXPRESSION REGULATION; INFLAMMATION; METABOLISM; MIDDLE AGED; PATHOLOGY; PHENOTYPE; ROTATOR CUFF; TENDON; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; CELLS, CULTURED; COHORT STUDIES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MACROPHAGES; MALE; MIDDLE AGED; PHENOTYPE; RECEPTORS, INTERLEUKIN-21; ROTATOR CUFF; TENDINOPATHY; TENDONS; YOUNG ADULT;

EID: 84897552264     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2014/481206     Document Type: Article

References (40)

1. Kannus P., Natri A., Etiology and pathophysiology of tendon ruptures in sports. Scandinavian Journal of Medicine and Science in Sports 1997 7 2 107 112 2-s2.0-0031113228 (Pubitemid 127521858)
2. Kannus P., Jozsa L., Jarvinen M., Garrett W. E. Jr., Speer K. P., Kirkendall D. T., Basic science of tendons. Principles and Practice of Orthopaedic Sports Medicine 2000 Lippincott and Wilkins 21 37
3. Hyman J., Rodeo S. A., Injury and repair of tendons and ligaments. Physical Medicine and Rehabilitation Clinics of North America 2000 11 2 267 288 2-s2.0-0034060809 (Pubitemid 30256560)
4. John T., Lodka D., Kohl B., Ertel W., Jammrath J., Conrad C., Stoll C., Busch C., Schulze-Tanzil G., Effect of pro-inflammatory and immunoregulatory cytokines on human tenocytes. Journal of Orthopaedic Research 2010 28 8 1071 1077 2-s2.0-77954728890 10.1002/jor.21079
5. Lin T. W., Cardenas L., Glaser D. L., Soslowsky L. J., Tendon healing in interleukin-4 and interleukin-6 knockout mice. Journal of Biomechanics 2006 39 1 61 69 2-s2.0-27744469758 10.1016/j.jbiomech.2004.11.009 (Pubitemid 41585009)
6. Abate M., Gravare Silbernagel K., Siljeholm C., Di Iorio A., De Amicis D., Salini V., Werner S., Paganelli R., Pathogenesis of tendinopathies: inflammation or degeneration? Arthritis Research & Therapy 2009 11 3 235 2-s2.0-77949681450
7. Matthews T. J., Hand G. C., Rees J. L., Athanasou N. A., Carr A. J., Pathology of the torn rotator cuff tendon. Reduction in potential for repair as tear size increases. The Journal of Bone and Joint Surgery B 2006 88 4 489 495
8. Millar N. L., Hueber A. J., Reilly J. H., Yinghua Xu Y. X., Fazzi U. G., Murrell G. A. C., McInnes I. B., Inflammation is present in early human tendinopathy. American Journal of Sports Medicine 2010 38 10 2085 2091 2-s2.0-77958194570 10.1177/0363546510372613
9. Millar N. L., Wei A. Q., Molloy T. J., Bonar F., Murrell G. A. C., Cytokines and apoptosis in supraspinatus tendinopathy. Journal of Bone and Joint Surgery B 2009 91 3 417 424 2-s2.0-63049132477 10.1302/0301-620X.91B3.21652
10. Oshiro W., Lou J., Xing X., Tu Y., Manske P. R., Flexor tendon healing in the rat: a histologic and gene expression study. Journal of Hand Surgery 2003 28 5 814 823 2-s2.0-0141620354 10.1016/S0363-5023(03)00366-6 (Pubitemid 37175365)
11. Nathan C., Points of control in inflammation. Nature 2002 420 6917 846 852 2-s2.0-0037180812 10.1038/nature01320 (Pubitemid 36019637)
12. Riley G., The pathogenesis of tendinopathy. A molecular perspective. Rheumatology 2004 43 2 131 142 2-s2.0-1242274622 10.1093/rheumatology/keg448 (Pubitemid 38219665)
13. Pufe T., Petersen W. J., Mentlein R., Tillmann B. N., The role of vasculature and angiogenesis for the pathogenesis of degenerative tendons disease. Scandinavian Journal of Medicine and Science in Sports 2005 15 4 211 222 2-s2.0-22744443137 10.1111/j.1600-0838.2005.00465.x (Pubitemid 41032385)
14. Tsuzaki M., Guyton G., Garrett W., Archambault J. M., Herzog W., Almekinders L., Bynum D., Yang X., Banes A. J., IL-1 β induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 β and IL-6 in human tendon cells. Journal of Orthopaedic Research 2003 21 2 256 264 2-s2.0-0037228988 10.1016/S0736-0266(02) 00141-9 (Pubitemid 36322545)
15. Tohyama H., Yasuda K., Uchida H., Nishihira J., The responses of extrinsic fibroblasts infiltrating the devitalised patellar tendon to IL-1 β are different from those of normal tendon fibroblasts. Journal of Bone and Joint Surgery B 2007 89 9 1261 1267 2-s2.0-35948977011 10.1302/0301-620X. 89B9.18053 (Pubitemid 350064060)
16. Hosaka Y., Kirisawa R., Yamamoto E., Ueda H., Iwai H., Takehana K., Localization of cytokines in tendinocytes of the superficial digital flexor tendon in the horse. Journal of Veterinary Medical Science 2002 64 10 945 947 2-s2.0-1842853800 10.1292/jvms.64.945 (Pubitemid 41379906)
17. Molloy T. J., Kemp M. W., Wang Y., Murrell G. A. C., Microarray analysis of the tendinopathic rat supraspinatus tendon: glutamate signaling and its potential role in tendon degeneration. Journal of Applied Physiology 2006 101 6 1702 1709 2-s2.0-33845431234 10.1152/japplphysiol.00386.2006 (Pubitemid 44904492)
18. Petersen W., Varoga D., Zantop T., Hassenpflug J., Mentlein R., Pufe T., Cyclic strain influences the expression of the vascular endothelial growth factor (VEGF) and the hypoxia inducible factor 1 alpha (HIF-1 α) in tendon fibroblasts. Journal of Orthopaedic Research 2004 22 4 847 853 2-s2.0-2942587279 10.1016/j.orthres.2003.11.009 (Pubitemid 38756267)
19. Uchida H., Tohyama H., Nagashima K., Ohba Y., Matsumoto H., Toyama Y., Yasuda K., Stress deprivation simultaneously induces over-expression of interleukin-1beta, tumor necrosis factor-alpha, and transforming growth factor-beta in fibroblasts and mechanical deterioration of the tissue in the patellar tendon. Journal of Biomechanics 2005 38 4 791 798 2-s2.0-13844274954 10.1016/j.jbiomech.2004.05.009 (Pubitemid 40248465)
20. Millar N. L., Murrell G. A., McInnes I. B., Alarmins in tendinopathy: unravelling new mechanisms in a common disease. Rheumatology 2013 52 5 769 779
21. Bubier J. A., Sproule T. J., Foreman O., Spolski R., Shaffer D. J., Morse H. C. III, Leonard W. J., Roopenian D. C., A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice. Proceedings of the National Academy of Sciences of the United States of America 2009 106 5 1518 1523 2-s2.0-60849107595 10.1073/pnas.0807309106
22. Parrish-Novak J., Foster D. C., Holly R. D., Clegg C. H., Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses. Journal of Leukocyte Biology 2002 72 5 856 863 2-s2.0-0036852893 (Pubitemid 35365159)
23. Distler J. H. W., Jüngel A., Kowal-Bielecka O., Michel B. A., Gay R. E., Sprott H., Matucci-Cerinic M., Chilla M., Reich K., Kalden J. R., Müller-Ladner U., Lorenz H. M., Gay S., Distler O., Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis. Arthritis and Rheumatism 2005 52 3 856 864 2-s2.0-20144362420 10.1002/art.20883 (Pubitemid 40365109)
24. Jüngel A., Distler J. H. W., Kurowska-Stolarska M., Seemayer C. A., Seibl R., Forster A., Michel B. A., Gay R. E., Emmrich F., Gay S., Distler O., Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis. Arthritis and Rheumatism 2004 50 5 1468 1476 2-s2.0-2342491493 10.1002/art.20218 (Pubitemid 38608068)
25. Liu Z., Yang L., Cui Y., Wang X., Guo C., Huang Z., Kan Q., Liu Z., Liu Y., IL-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease. Inflammatory Bowel Diseases 2009 15 8 1133 1144 2-s2.0-66149159613 10.1002/ibd.20923
26. Millar N. L., Wei A. Q., Molloy T. J., Bonar F., Murrell G. A. C., Heat shock protein and apoptosis in supraspinatus tendinopathy. Clinical Orthopaedics and Related Research 2008 466 7 1569 1576 2-s2.0-45849118761 10.1007/s11999-008-0265-9
27. Wu X. L., Baldwick C., Briggs L., Murrell G. A. C., Arthroscopic undersurface rotator cuff repair. Techniques in Shoulder and Elbow Surgery 2009 10 3 112 118 2-s2.0-69849101277 10.1097/BTE.0b013e3181ac1a92
28. Millar N. L., Wu X., Tantau R., Silverstone E., Murrell G. A. C., Open versus two forms of arthroscopic rotator cuff repair. Clinical Orthopaedics and Related Research 2009 467 4 966 978 2-s2.0-62449173058 10.1007/s11999-009-0706-0
29. McInnes I. B., Leung B. P., Field M., Wei X. Q., Huang F.-P., Sturrock R. D., Kinninmonth A., Weidner J., Mumford R., Liew F. Y., Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients. Journal of Experimental Medicine 1996 184 4 1519 1524 2-s2.0-10244253892 10.1084/jem.184.4.1519 (Pubitemid 26354707)
30. Xu D., Jiang H.-R., Li Y., Pushparaj P. N., Kurowska-Stolarska M., Leung B. P., Mu R., Tay H. K., McKenzie A. N. J., McInnes I. B., Melendez A. J., Liew F. Y., IL-33 exacerbates autoantibody-induced arthritis. Journal of Immunology 2010 184 5 2620 2626 2-s2.0-77951888994 10.4049/jimmunol.0902685
31. Van Heel D. A., Franke L., Hunt K. A., Gwilliam R., Zhernakova A., Inouye M., Wapenaar M. C., Barnardo M. C. N. M., Bethel G., Holmes G. K. T., Feighery C., Jewell D., Kelleher D., Kumar P., Travis S., Walters J. R. F., Sanders D. S., Howdle P., Swift J., Playford R. J., McLaren W. M., Mearin M. L., Mulder C. J., McManus R., McGinnis R., Cardon L. R., Deloukas P., Wijmenga C., A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nature Genetics 2007 39 7 827 829 2-s2.0-34347324029 10.1038/ng2058 (Pubitemid 47014494)
32. Festen E. A. M., Goyette P., Scott R., Annese V., Zhernakova A., Lian J., Lefèbvre C., Brant S. R., Cho J. H., Silverberg M. S., Taylor K. D., De Jong D. J., Stokkers P. C., Mcgovern D., Palmieri O., Achkar J.-P., Xavier R. J., Daly M. J., Duerr R. H., Wijmenga C., Weersma R. K., Rioux J. D., Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis. Gut 2009 58 6 799 804 2-s2.0-64549104048 10.1136/gut.2008.166918
33. Chatterjee R., Batra J., Ghosh B., A common exonic variant of Interleukin21 confers susceptibility to atopic asthma. International Archives of Allergy and Immunology 2009 148 2 137 146 2-s2.0-51849118676 10.1159/000155744
34. Distler J. H. W., Jüngel A., Kowal-Bielecka O., Michel B. A., Gay R. E., Sprott H., Matucci-Cerinic M., Chilla M., Reich K., Kalden J. R., Müller-Ladner U., Lorenz H. M., Gay S., Distler O., Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis. Arthritis and Rheumatism 2005 52 3 856 864 2-s2.0-20144362420 10.1002/art.20883 (Pubitemid 40365109)
35. Andersson A. K., Feldmann M., Brennan F. M., Neutralizing IL-21 and IL-15 inhibits pro-inflammatory cytokine production in rheumatoid arthritis. Scandinavian Journal of Immunology 2008 68 1 103 111 2-s2.0-44849114296 10.1111/j.1365-3083.2008.02118.x (Pubitemid 351798402)
36. Yuan F. L., Hu W., Lu W. G., Targeting interleukin-21 in rheumatoid arthritis. Molecular Biology Reports 2011 38 3 1717 1721 10.1007/s11033-010- 0285-x
37. Fina D., Sarra M., Caruso R., del Vecchio Blanco G., Pallone F., MacDonald T. T., Monteleone G., Interleukin 21 contributes to the mucosal T helper cell type 1 response in coeliac disease. Gut 2008 57 7 887 892 2-s2.0-46349089381 10.1136/gut.2007.129882 (Pubitemid 351919521)
38. Monteleone G., Caruso R., Fina D., Peluso I., Gioia V., Stolfi C., Fantini M. C., Caprioli F., Tersigni R., Alessandroni L., MacDonald T. T., Pallone F., Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21. Gut 2006 55 12 1774 1780 2-s2.0-33845447347 10.1136/gut.2006.093187 (Pubitemid 44893577)
39. Mueller T. D., Zhang J.-L., Sebald W., Duschl A., Structure, binding, and antagonists in the IL-4/IL-13 receptor system. Biochimica et Biophysica Acta 2002 1592 3 237 250 2-s2.0-0037064548 10.1016/S0167-4889(02)00318-X (Pubitemid 35284881)
40. Asao H., Okuyama C., Kumaki S., Ishii N., Tsuchiya S., Foster D., Sugamura K., Cutting edge: the common γ -chain is an indispensable subunit of the IL-21 receptor complex. Journal of Immunology 2001 167 1 1 5 2-s2.0-0035400054 (Pubitemid 32567752)