메뉴 건너뛰기




Volumn 1, Issue 1, 2010, Pages 60-71

Stem cell transplantation for enhancement of learning and memory in adult neurocognitive disorders

Author keywords

Aging; Alzheimer's disease; Learning and memory; Neural stem cells; Stroke; Traumatic brain injury

Indexed keywords


EID: 84897538025     PISSN: None     EISSN: 21525250     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (103)
  • 1
    • 77951498581 scopus 로고    scopus 로고
    • New neurons and new memories: How does adult hippocampal neurogenesis affect learning and memory?
    • Deng W, Aimone JB, Gage FH (2010). New neurons and new memories: How does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci, 11:339-350.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 339-350
    • Deng, W.1    Aimone, J.B.2    Gage, F.H.3
  • 2
    • 0010529277 scopus 로고
    • Loss of recent memory after bilateral hippocampal lesions
    • Scoville WB, Milner B (1957). Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychiatry, 20:11-21.
    • (1957) J Neurol Neurosurg Psychiatry , vol.20 , pp. 11-21
    • Scoville, W.B.1    Milner, B.2
  • 3
    • 0030636251 scopus 로고    scopus 로고
    • Declarative memory: Insights from cognitive neurobiology
    • Eichenbaum H (1997). Declarative memory: Insights from cognitive neurobiology. Annu Rev Psychol, 48:547-572.
    • (1997) Annu Rev Psychol , vol.48 , pp. 547-572
    • Eichenbaum, H.1
  • 4
    • 1442351120 scopus 로고    scopus 로고
    • Contributions of memory circuits to language: The declarative/procedural model
    • Ullman MT (2004). Contributions of memory circuits to language: The declarative/procedural model. Cognition, 92:231-270.
    • (2004) Cognition , vol.92 , pp. 231-270
    • Ullman, M.T.1
  • 5
    • 0026847039 scopus 로고
    • Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans
    • Squire LR (1992). Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans. Psychol Rev, 99:195-231.
    • (1992) Psychol Rev , vol.99 , pp. 195-231
    • Squire, L.R.1
  • 6
    • 0021337699 scopus 로고
    • Hippocampectomy disrupts acquisition and retention of learned conditional responding
    • Ross RT, Orr WB, Holland PC, Berger TW (1984). Hippocampectomy disrupts acquisition and retention of learned conditional responding. Behav Neurosci, 98:211-225.
    • (1984) Behav Neurosci , vol.98 , pp. 211-225
    • Ross, R.T.1    Orr, W.B.2    Holland, P.C.3    Berger, T.W.4
  • 7
    • 0030477676 scopus 로고    scopus 로고
    • Memory systems in the brain and localization of a memory
    • Thompson RF, Kim JJ (1996). Memory systems in the brain and localization of a memory. Proc Natl Acad Sci U S A, 93:13438-13444.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 13438-13444
    • Thompson, R.F.1    Kim, J.J.2
  • 8
    • 0017276692 scopus 로고
    • Neuronal substrate of classical conditioning in the hippocampus
    • Berger TW, Alger B, Thompson RF (1976). Neuronal substrate of classical conditioning in the hippocampus. Science, 192:483-485.
    • (1976) Science , vol.192 , pp. 483-485
    • Berger, T.W.1    Alger, B.2    Thompson, R.F.3
  • 9
    • 0006073716 scopus 로고
    • Identification of pyramidal cells as the critical elements in hippocampal neuronal plasticity during learning
    • Berger TW, Thompson RF (1978). Identification of pyramidal cells as the critical elements in hippocampal neuronal plasticity during learning. Proc Natl Acad Sci U S A, 75:1572-1576.
    • (1978) Proc Natl Acad Sci U S A , vol.75 , pp. 1572-1576
    • Berger, T.W.1    Thompson, R.F.2
  • 10
    • 0021262466 scopus 로고
    • The biochemistry of memory: A new and specific hypothesis
    • Lynch G, Baudry M (1984). The biochemistry of memory: A new and specific hypothesis. Science, 224:1057-1063.
    • (1984) Science , vol.224 , pp. 1057-1063
    • Lynch, G.1    Baudry, M.2
  • 11
    • 58149442669 scopus 로고
    • Cognitive maps in rats and men
    • Tolman EC (1948). Cognitive maps in rats and men. Psychol Rev, 55:189-208.
    • (1948) Psychol Rev , vol.55 , pp. 189-208
    • Tolman, E.C.1
  • 12
    • 0023205908 scopus 로고
    • Single unit activity in the rat hippocampus during a spatial memory task
    • O'Keefe J, Speakman A (1987). Single unit activity in the rat hippocampus during a spatial memory task. Exp Brain Res, 68:1-27.
    • (1987) Exp Brain Res , vol.68 , pp. 1-27
    • O'Keefe, J.1    Speakman, A.2
  • 13
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • Morris R (1984). Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods, 11:47-60.
    • (1984) J Neurosci Methods , vol.11 , pp. 47-60
    • Morris, R.1
  • 14
    • 0018942696 scopus 로고
    • Neuroanatomical bases of spatial memory
    • Becker JT, Walker JA, Olton DS (1980). Neuroanatomical bases of spatial memory. Brain Res, 200:307-320.
    • (1980) Brain Res , vol.200 , pp. 307-320
    • Becker, J.T.1    Walker, J.A.2    Olton, D.S.3
  • 15
    • 0025365108 scopus 로고
    • Hippocampectomy disrupts trace eye-blink conditioning in rabbits
    • Moyer JR, Jr., Deyo RA, Disterhoft JF (1990). Hippocampectomy disrupts trace eye-blink conditioning in rabbits. Behav Neurosci, 104:243-252.
    • (1990) Behav Neurosci , vol.104 , pp. 243-252
    • Moyer Jr., J.R.1    Deyo, R.A.2    Disterhoft, J.F.3
  • 16
    • 0023035964 scopus 로고
    • Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response
    • Solomon PR, Vander Schaaf ER, Thompson RF, Weisz DJ (1986). Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response. Behav Neurosci, 100:729-744.
    • (1986) Behav Neurosci , vol.100 , pp. 729-744
    • Solomon, P.R.1    Vander Schaaf, E.R.2    Thompson, R.F.3    Weisz, D.J.4
  • 17
    • 0026514823 scopus 로고
    • Modality-specific retrograde amnesia of fear
    • Kim JJ, Fanselow MS (1992). Modality-specific retrograde amnesia of fear. Science, 256:675-677.
    • (1992) Science , vol.256 , pp. 675-677
    • Kim, J.J.1    Fanselow, M.S.2
  • 18
    • 0026635574 scopus 로고
    • Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning
    • Phillips RG, LeDoux JE (1992). Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci, 106:274-285.
    • (1992) Behav Neurosci , vol.106 , pp. 274-285
    • Phillips, R.G.1    LeDoux, J.E.2
  • 19
    • 0030007730 scopus 로고    scopus 로고
    • Maze procedures: The radial-arm and water maze compared
    • Hodges H (1996). Maze procedures: The radial-arm and water maze compared. Brain Res Cogn Brain Res, 3:167-181.
    • (1996) Brain Res Cogn Brain Res , vol.3 , pp. 167-181
    • Hodges, H.1
  • 21
    • 0019303352 scopus 로고
    • Hippocampus: Cognitive map or working memory?
    • Nadel L, MacDonald L (1980). Hippocampus: Cognitive map or working memory? Behav Neural Biol, 29:405-409.
    • (1980) Behav Neural Biol , vol.29 , pp. 405-409
    • Nadel, L.1    MacDonald, L.2
  • 22
    • 0025514353 scopus 로고
    • Hippocampal representation in place learning
    • Eichenbaum H, Stewart C, Morris RG (1990). Hippocampal representation in place learning. J Neurosci, 10:3531-3542.
    • (1990) J Neurosci , vol.10 , pp. 3531-3542
    • Eichenbaum, H.1    Stewart, C.2    Morris, R.G.3
  • 23
    • 0025301034 scopus 로고
    • Damage to ceruleo-cortical noradrenergic projections impairs locally cued but enhances spatially cued water maze acquisition
    • Selden NR, Cole BJ, Everitt BJ, Robbins TW (1990). Damage to ceruleo-cortical noradrenergic projections impairs locally cued but enhances spatially cued water maze acquisition. Behav Brain Res, 39:29-51.
    • (1990) Behav Brain Res , vol.39 , pp. 29-51
    • Selden, N.R.1    Cole, B.J.2    Everitt, B.J.3    Robbins, T.W.4
  • 24
    • 0027257348 scopus 로고
    • On the role of the hippocampus in learning and memory in the rat
    • Jarrard LE (1993). On the role of the hippocampus in learning and memory in the rat. Behav Neural Biol, 60:9-26.
    • (1993) Behav Neural Biol , vol.60 , pp. 9-26
    • Jarrard, L.E.1
  • 26
    • 0028104679 scopus 로고
    • Cognitive deficits induced by global cerebral ischaemia: Relationship to brain damage and reversal by transplants
    • Nunn J, Hodges H (1994). Cognitive deficits induced by global cerebral ischaemia: Relationship to brain damage and reversal by transplants. Behav Brain Res, 65:1-31.
    • (1994) Behav Brain Res , vol.65 , pp. 1-31
    • Nunn, J.1    Hodges, H.2
  • 27
    • 0022619046 scopus 로고
    • The effects of hippocampal lesions upon spatial and non-spatial tests of working memory
    • Aggleton JP, Hunt PR, Rawlins JN (1986). The effects of hippocampal lesions upon spatial and non-spatial tests of working memory. Behav Brain Res, 19:133-146.
    • (1986) Behav Brain Res , vol.19 , pp. 133-146
    • Aggleton, J.P.1    Hunt, P.R.2    Rawlins, J.N.3
  • 28
    • 0027275311 scopus 로고
    • Medial septal lesions disrupt spatial, but not nonspatial, working memory in rats
    • Kelsey JE, Vargas H (1993). Medial septal lesions disrupt spatial, but not nonspatial, working memory in rats. Behav Neurosci, 107:565-574.
    • (1993) Behav Neurosci , vol.107 , pp. 565-574
    • Kelsey, J.E.1    Vargas, H.2
  • 29
    • 0026068681 scopus 로고
    • Object recognition memory in the rat: The role of the hippocampus
    • Rothblat LA, Kromer LF (1991). Object recognition memory in the rat: The role of the hippocampus. Behav Brain Res, 42:25-32.
    • (1991) Behav Brain Res , vol.42 , pp. 25-32
    • Rothblat, L.A.1    Kromer, L.F.2
  • 30
    • 0036244335 scopus 로고    scopus 로고
    • Hippocampal damage and exploratory preferences in rats: Memory for objects, places, and contexts
    • Mumby DG, Gaskin S, Glenn MJ, Schramek TE, Lehmann H (2002). Hippocampal damage and exploratory preferences in rats: Memory for objects, places, and contexts. Learn Mem, 9:49-57.
    • (2002) Learn Mem , vol.9 , pp. 49-57
    • Mumby, D.G.1    Gaskin, S.2    Glenn, M.J.3    Schramek, T.E.4    Lehmann, H.5
  • 31
    • 0026517358 scopus 로고
    • Exploratory activity and response to a spatial change in rats with hippocampal or posterior parietal cortical lesions
    • Save E, Buhot MC, Foreman N, Thinus-Blanc C (1992). Exploratory activity and response to a spatial change in rats with hippocampal or posterior parietal cortical lesions. Behav Brain Res, 47:113-127.
    • (1992) Behav Brain Res , vol.47 , pp. 113-127
    • Save, E.1    Buhot, M.C.2    Foreman, N.3    Thinus-Blanc, C.4
  • 33
    • 39449107305 scopus 로고    scopus 로고
    • Transgenic inhibition of synaptic transmission reveals role of ca3 output in hippocampal learning
    • Nakashiba T, Young JZ, McHugh TJ, Buhl DL, Tonegawa S (2008). Transgenic inhibition of synaptic transmission reveals role of ca3 output in hippocampal learning. Science, 319:1260-1264.
    • (2008) Science , vol.319 , pp. 1260-1264
    • Nakashiba, T.1    Young, J.Z.2    McHugh, T.J.3    Buhl, D.L.4    Tonegawa, S.5
  • 35
    • 0036436191 scopus 로고    scopus 로고
    • Neurogenesis may relate to some but not all types of hippocampal-dependent learning
    • Shors TJ, Townsend DA, Zhao M, Kozorovitskiy Y, Gould E (2002). Neurogenesis may relate to some but not all types of hippocampal-dependent learning. Hippocampus, 12:578-584.
    • (2002) Hippocampus , vol.12 , pp. 578-584
    • Shors, T.J.1    Townsend, D.A.2    Zhao, M.3    Kozorovitskiy, Y.4    Gould, E.5
  • 36
    • 70350537113 scopus 로고    scopus 로고
    • Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain
    • Deng W, Saxe MD, Gallina IS, Gage FH (2009). Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain. J Neurosci, 29:13532-13542.
    • (2009) J Neurosci , vol.29 , pp. 13532-13542
    • Deng, W.1    Saxe, M.D.2    Gallina, I.S.3    Gage, F.H.4
  • 38
    • 0038182466 scopus 로고    scopus 로고
    • Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat
    • Madsen TM, Kristjansen PE, Bolwig TG, Wortwein G (2003). Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat. Neuroscience, 119:635-642.
    • (2003) Neuroscience , vol.119 , pp. 635-642
    • Madsen, T.M.1    Kristjansen, P.E.2    Bolwig, T.G.3    Wortwein, G.4
  • 42
    • 38149027068 scopus 로고    scopus 로고
    • Impaired spatial representation in ca1 after lesion of direct input from entorhinal cortex
    • Brun VH, Leutgeb S, Wu HQ, Schwarcz R, Witter MP, Moser EI, Moser MB (2008). Impaired spatial representation in ca1 after lesion of direct input from entorhinal cortex. Neuron, 57:290-302.
    • (2008) Neuron , vol.57 , pp. 290-302
    • Brun, V.H.1    Leutgeb, S.2    Wu, H.Q.3    Schwarcz, R.4    Witter, M.P.5    Moser, E.I.6    Moser, M.B.7
  • 43
    • 65549133778 scopus 로고    scopus 로고
    • Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies
    • Garthe A, Behr J, Kempermann G (2009). Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies. PLoS One, 4:e5464.
    • (2009) PLoS One , vol.4 , pp. e5464
    • Garthe, A.1    Behr, J.2    Kempermann, G.3
  • 44
    • 40949122425 scopus 로고    scopus 로고
    • Electroconvulsive seizure restores neurogenesis and hippocampus-dependent fear memory after disruption by irradiation
    • Warner-Schmidt JL, Madsen TM, Duman RS (2008). Electroconvulsive seizure restores neurogenesis and hippocampus-dependent fear memory after disruption by irradiation. Eur J Neurosci, 27:1485-1493.
    • (2008) Eur J Neurosci , vol.27 , pp. 1485-1493
    • Warner-Schmidt, J.L.1    Madsen, T.M.2    Duman, R.S.3
  • 45
    • 33645096734 scopus 로고    scopus 로고
    • Inhibition of neurogenesis interferes with hippocampus-dependent memory function
    • Winocur G, Wojtowicz JM, Sekeres M, Snyder JS, Wang S (2006). Inhibition of neurogenesis interferes with hippocampus-dependent memory function. Hippocampus, 16:296-304.
    • (2006) Hippocampus , vol.16 , pp. 296-304
    • Winocur, G.1    Wojtowicz, J.M.2    Sekeres, M.3    Snyder, J.S.4    Wang, S.5
  • 47
    • 39149099035 scopus 로고    scopus 로고
    • A role for adult tlx-positive neural stem cells in learning and behaviour
    • Zhang CL, Zou Y, He W, Gage FH, Evans RM (2008). A role for adult tlx-positive neural stem cells in learning and behaviour. Nature, 451:1004-1007.
    • (2008) Nature , vol.451 , pp. 1004-1007
    • Zhang, C.L.1    Zou, Y.2    He, W.3    Gage, F.H.4    Evans, R.M.5
  • 49
    • 49249116020 scopus 로고    scopus 로고
    • Behavior of neural stem cells in the alzheimer brain
    • Waldau B, Shetty AK (2008). Behavior of neural stem cells in the alzheimer brain. Cell Mol Life Sci, 65:2372-2384.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 2372-2384
    • Waldau, B.1    Shetty, A.K.2
  • 51
    • 0034060991 scopus 로고    scopus 로고
    • Transplanted cns stem cells form functional synapses in vivo
    • Auerbach JM, Eiden MV, McKay RD (2000). Transplanted cns stem cells form functional synapses in vivo. Eur J Neurosci, 12:1696-1704.
    • (2000) Eur J Neurosci , vol.12 , pp. 1696-1704
    • Auerbach, J.M.1    Eiden, M.V.2    McKay, R.D.3
  • 52
    • 0037168599 scopus 로고    scopus 로고
    • Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry
    • Englund U, Bjorklund A, Wictorin K, Lindvall O, Kokaia M (2002). Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry. Proc Natl Acad Sci U S A, 99:17089-17094.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 17089-17094
    • Englund, U.1    Bjorklund, A.2    Wictorin, K.3    Lindvall, O.4    Kokaia, M.5
  • 54
    • 50449092677 scopus 로고    scopus 로고
    • Embryonic stem cell-derived neural precursor cells improve memory dysfunction in abeta(1-40) injured rats
    • Tang J, Xu H, Fan X, Li D, Rancourt D, Zhou G, Li Z, Yang L (2008). Embryonic stem cell-derived neural precursor cells improve memory dysfunction in abeta(1-40) injured rats. Neurosci Res, 62:86-96.
    • (2008) Neurosci Res , vol.62 , pp. 86-96
    • Tang, J.1    Xu, H.2    Fan, X.3    Li, D.4    Rancourt, D.5    Zhou, G.6    Li, Z.7    Yang, L.8
  • 55
    • 45849098696 scopus 로고    scopus 로고
    • Bdnf improves the effects of neural stem cells on the rat model of alzheimer's disease with unilateral lesion of fimbria-fornix
    • Xuan AG, Long DH, Gu HG, Yang DD, Hong LP, Leng SL (2008). Bdnf improves the effects of neural stem cells on the rat model of alzheimer's disease with unilateral lesion of fimbria-fornix. Neurosci Lett, 440:331-335.
    • (2008) Neurosci Lett , vol.440 , pp. 331-335
    • Xuan, A.G.1    Long, D.H.2    Gu, H.G.3    Yang, D.D.4    Hong, L.P.5    Leng, S.L.6
  • 56
    • 58149330092 scopus 로고    scopus 로고
    • Effects of engrafted neural stem cells in alzheimer's disease rats
    • Xuan AG, Luo M, Ji WD, Long DH (2009). Effects of engrafted neural stem cells in alzheimer's disease rats. Neurosci Lett, 450:167-171.
    • (2009) Neurosci Lett , vol.450 , pp. 167-171
    • Xuan, A.G.1    Luo, M.2    Ji, W.D.3    Long, D.H.4
  • 57
    • 69949139798 scopus 로고    scopus 로고
    • Transplantation of primed or unprimed mouse embryonic stem cell-derived neural precursor cells improves cognitive function in alzheimerian rats
    • Moghadam FH, Alaie H, Karbalaie K, Tanhaei S, Nasr Esfahani MH, Baharvand H (2009). Transplantation of primed or unprimed mouse embryonic stem cell-derived neural precursor cells improves cognitive function in alzheimerian rats. Differentiation, 78:59-68.
    • (2009) Differentiation , vol.78 , pp. 59-68
    • Moghadam, F.H.1    Alaie, H.2    Karbalaie, K.3    Tanhaei, S.4    Nasr Esfahani, M.H.5    Baharvand, H.6
  • 58
    • 0030248408 scopus 로고    scopus 로고
    • Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro
    • Okabe S, Forsberg-Nilsson K, Spiro AC, Segal M, McKay RD (1996). Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro. Mech Dev, 59:89-102.
    • (1996) Mech Dev , vol.59 , pp. 89-102
    • Okabe, S.1    Forsberg-Nilsson, K.2    Spiro, A.C.3    Segal, M.4    McKay, R.D.5
  • 60
    • 42949166256 scopus 로고    scopus 로고
    • Transplantation of ngf-gene-modified bone marrow stromal cells into a rat model of alzheimer' disease
    • Li LY, Li JT, Wu QY, Li J, Feng ZT, Liu S, Wang TH (2008). Transplantation of ngf-gene-modified bone marrow stromal cells into a rat model of alzheimer' disease. J Mol Neurosci, 34:157-163.
    • (2008) J Mol Neurosci , vol.34 , pp. 157-163
    • Li, L.Y.1    Li, J.T.2    Wu, Q.Y.3    Li, J.4    Feng, Z.T.5    Liu, S.6    Wang, T.H.7
  • 61
    • 0036978779 scopus 로고    scopus 로고
    • Improvement of spatial learning and memory after adenovirus-mediated transfer of the nerve growth factor gene to aged rat brain
    • Zou L, Yuan X, Long Y, Shine HD, Yang K (2002). Improvement of spatial learning and memory after adenovirus-mediated transfer of the nerve growth factor gene to aged rat brain. Hum Gene Ther, 13:2173-2184.
    • (2002) Hum Gene Ther , vol.13 , pp. 2173-2184
    • Zou, L.1    Yuan, X.2    Long, Y.3    Shine, H.D.4    Yang, K.5
  • 62
    • 0034534819 scopus 로고    scopus 로고
    • Intraparenchymal ngf infusions rescue degenerating cholinergic neurons
    • Tuszynski MH (2000). Intraparenchymal ngf infusions rescue degenerating cholinergic neurons. Cell Transplant, 9:629-636.
    • (2000) Cell Transplant , vol.9 , pp. 629-636
    • Tuszynski, M.H.1
  • 63
    • 0032411163 scopus 로고    scopus 로고
    • Targeted intraparenchymal delivery of human ngf by gene transfer to the primate basal forebrain for 3 months does not accelerate beta-amyloid plaque deposition
    • Tuszynski MH, Smith DE, Roberts J, McKay H, Mufson E (1998). Targeted intraparenchymal delivery of human ngf by gene transfer to the primate basal forebrain for 3 months does not accelerate beta-amyloid plaque deposition. Exp Neurol, 154:573-582.
    • (1998) Exp Neurol , vol.154 , pp. 573-582
    • Tuszynski, M.H.1    Smith, D.E.2    Roberts, J.3    McKay, H.4    Mufson, E.5
  • 64
    • 0036249987 scopus 로고    scopus 로고
    • Amelioration of cholinergic neurons dysfunction in aged rats depends on the continuous supply of ngf
    • Niewiadomska G, Komorowski S, Baksalerska-Pazera M (2002). Amelioration of cholinergic neurons dysfunction in aged rats depends on the continuous supply of ngf. Neurobiol Aging, 23:601-613.
    • (2002) Neurobiol Aging , vol.23 , pp. 601-613
    • Niewiadomska, G.1    Komorowski, S.2    Baksalerska-Pazera, M.3
  • 65
    • 0034175581 scopus 로고    scopus 로고
    • Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy
    • Ruberti F, Capsoni S, Comparini A, Di Daniel E, Franzot J, Gonfloni S, Rossi G, Berardi N, Cattaneo A (2000). Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy. J Neurosci, 20:2589-2601.
    • (2000) J Neurosci , vol.20 , pp. 2589-2601
    • Ruberti, F.1    Capsoni, S.2    Comparini, A.3    Di Daniel, E.4    Franzot, J.5    Gonfloni, S.6    Rossi, G.7    Berardi, N.8    Cattaneo, A.9
  • 66
    • 0034284813 scopus 로고    scopus 로고
    • Ngf gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats
    • Klein RL, Hirko AC, Meyers CA, Grimes JR, Muzyczka N, Meyer EM (2000). Ngf gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats. Brain Res, 875:144-151.
    • (2000) Brain Res , vol.875 , pp. 144-151
    • Klein, R.L.1    Hirko, A.C.2    Meyers, C.A.3    Grimes, J.R.4    Muzyczka, N.5    Meyer, E.M.6
  • 68
    • 58149333136 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells reduce brain amyloid-beta deposition and accelerate the activation of microglia in an acutely induced alzheimer's disease mouse model
    • Lee JK, Jin HK, Bae JS (2009). Bone marrow-derived mesenchymal stem cells reduce brain amyloid-beta deposition and accelerate the activation of microglia in an acutely induced alzheimer's disease mouse model. Neurosci Lett, 450:136-141.
    • (2009) Neurosci Lett , vol.450 , pp. 136-141
    • Lee, J.K.1    Jin, H.K.2    Bae, J.S.3
  • 69
    • 74549156242 scopus 로고    scopus 로고
    • Neural progenitor cells attenuate inflammatory reactivity and neuronal loss in an animal model of inflamed ad brain
    • Ryu JK, Cho T, Wang YT, McLarnon JG (2009). Neural progenitor cells attenuate inflammatory reactivity and neuronal loss in an animal model of inflamed ad brain. J Neuroinflammation, 6:39.
    • (2009) J Neuroinflammation , vol.6 , pp. 39
    • Ryu, J.K.1    Cho, T.2    Wang, Y.T.3    McLarnon, J.G.4
  • 70
    • 77149146814 scopus 로고    scopus 로고
    • Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in alzheimer's disease mice by modulation of immune responses
    • Lee JK, Jin HK, Endo S, Schuchman EH, Carter JE, Bae JS (2010). Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in alzheimer's disease mice by modulation of immune responses. Stem Cells, 28:329-343.
    • (2010) Stem Cells , vol.28 , pp. 329-343
    • Lee, J.K.1    Jin, H.K.2    Endo, S.3    Schuchman, E.H.4    Carter, J.E.5    Bae, J.S.6
  • 73
    • 0035828120 scopus 로고    scopus 로고
    • Conditioned blocking is re-established by neurotransplantation in mature rats
    • Moron I, Ballesteros MA, Valouskova V, Gallo M (2001). Conditioned blocking is re-established by neurotransplantation in mature rats. Neuroreport, 12:2297-2301.
    • (2001) Neuroreport , vol.12 , pp. 2297-2301
    • Moron, I.1    Ballesteros, M.A.2    Valouskova, V.3    Gallo, M.4
  • 74
    • 0031938271 scopus 로고    scopus 로고
    • Protective effects of fetal neocortical transplants on cognitive function and neuron size in rats with congenital micrencephaly
    • Lee MH, Rabe A (1998). Protective effects of fetal neocortical transplants on cognitive function and neuron size in rats with congenital micrencephaly. Behav Brain Res, 90:147-156.
    • (1998) Behav Brain Res , vol.90 , pp. 147-156
    • Lee, M.H.1    Rabe, A.2
  • 75
    • 0023697229 scopus 로고
    • Cholinergic grafts in the neocortex or hippocampus of aged rats: Reduction of delay-dependent deficits in the delayed non-matching to position task
    • Dunnett SB, Badman F, Rogers DC, Evenden JL, Iversen SD (1988). Cholinergic grafts in the neocortex or hippocampus of aged rats: Reduction of delay-dependent deficits in the delayed non-matching to position task. Exp Neurol, 102:57-64.
    • (1988) Exp Neurol , vol.102 , pp. 57-64
    • Dunnett, S.B.1    Badman, F.2    Rogers, D.C.3    Evenden, J.L.4    Iversen, S.D.5
  • 76
    • 0022487150 scopus 로고
    • Cholinergic septal grafts into the hippocampal formation improve spatial learning and memory in aged rats by an atropine-sensitive mechanism
    • Gage FH, Bjorklund A (1986). Cholinergic septal grafts into the hippocampal formation improve spatial learning and memory in aged rats by an atropine-sensitive mechanism. J Neurosci, 6:2837-2847.
    • (1986) J Neurosci , vol.6 , pp. 2837-2847
    • Gage, F.H.1    Bjorklund, A.2
  • 77
    • 0021203981 scopus 로고
    • Intrahippocampal septal grafts ameliorate learning impairments in aged rats
    • Gage FH, Bjorklund A, Stenevi U, Dunnett SB, Kelly PA (1984). Intrahippocampal septal grafts ameliorate learning impairments in aged rats. Science, 225:533-536.
    • (1984) Science , vol.225 , pp. 533-536
    • Gage, F.H.1    Bjorklund, A.2    Stenevi, U.3    Dunnett, S.B.4    Kelly, P.A.5
  • 78
    • 0043192397 scopus 로고    scopus 로고
    • Pretreatment of donor cells with fgf-2 enhances survival of fetal hippocampal ca3 cell transplants in the chronically lesioned young adult hippocampus
    • Zaman V, Shetty AK (2003). Pretreatment of donor cells with fgf-2 enhances survival of fetal hippocampal ca3 cell transplants in the chronically lesioned young adult hippocampus. Exp Neurol, 183:11-24.
    • (2003) Exp Neurol , vol.183 , pp. 11-24
    • Zaman, V.1    Shetty, A.K.2
  • 79
    • 0029902122 scopus 로고    scopus 로고
    • Long-term functional recovery from age-induced spatial memory impairments by nerve growth factor gene transfer to the rat basal forebrain
    • Martinez-Serrano A, Fischer W, Soderstrom S, Ebendal T, Bjorklund A (1996). Long-term functional recovery from age-induced spatial memory impairments by nerve growth factor gene transfer to the rat basal forebrain. Proc Natl Acad Sci U S A, 93:6355-6360.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 6355-6360
    • Martinez-Serrano, A.1    Fischer, W.2    Soderstrom, S.3    Ebendal, T.4    Bjorklund, A.5
  • 80
    • 0032539698 scopus 로고    scopus 로고
    • Ex vivo nerve growth factor gene transfer to the basal forebrain in presymptomatic middle-aged rats prevents the development of cholinergic neuron atrophy and cognitive impairment during aging
    • Martinez-Serrano A, Bjorklund A (1998). Ex vivo nerve growth factor gene transfer to the basal forebrain in presymptomatic middle-aged rats prevents the development of cholinergic neuron atrophy and cognitive impairment during aging. Proc Natl Acad Sci U S A, 95:1858-1863.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 1858-1863
    • Martinez-Serrano, A.1    Bjorklund, A.2
  • 81
    • 0028965223 scopus 로고
    • Somatic gene transfer of ngf to the aged brain: Behavioral and morphological amelioration
    • Chen KS, Gage FH (1995). Somatic gene transfer of ngf to the aged brain: Behavioral and morphological amelioration. J Neurosci, 15:2819-2825.
    • (1995) J Neurosci , vol.15 , pp. 2819-2825
    • Chen, K.S.1    Gage, F.H.2
  • 82
    • 0029080919 scopus 로고
    • Reversal of age-dependent cognitive impairments and cholinergic neuron atrophy by ngf-secreting neural progenitors grafted to the basal forebrain
    • Martinez-Serrano A, Fischer W, Bjorklund A (1995). Reversal of age-dependent cognitive impairments and cholinergic neuron atrophy by ngf-secreting neural progenitors grafted to the basal forebrain. Neuron, 15:473-484.
    • (1995) Neuron , vol.15 , pp. 473-484
    • Martinez-Serrano, A.1    Fischer, W.2    Bjorklund, A.3
  • 84
    • 0034063408 scopus 로고    scopus 로고
    • Conditionally immortalized, multipotential and multifunctional neural stem cell lines as an approach to clinical transplantation
    • Gray JA, Grigoryan G, Virley D, Patel S, Sinden JD, Hodges H (2000). Conditionally immortalized, multipotential and multifunctional neural stem cell lines as an approach to clinical transplantation. Cell Transplant, 9:153-168.
    • (2000) Cell Transplant , vol.9 , pp. 153-168
    • Gray, J.A.1    Grigoryan, G.2    Virley, D.3    Patel, S.4    Sinden, J.D.5    Hodges, H.6
  • 85
    • 0035826914 scopus 로고    scopus 로고
    • Human neural stem cells improve cognitive function of aged brain
    • Qu T, Brannen CL, Kim HM, Sugaya K (2001). Human neural stem cells improve cognitive function of aged brain. Neuroreport, 12:1127-1132.
    • (2001) Neuroreport , vol.12 , pp. 1127-1132
    • Qu, T.1    Brannen, C.L.2    Kim, H.M.3    Sugaya, K.4
  • 86
    • 17044454588 scopus 로고    scopus 로고
    • Motor and cognitive recovery induced by bone marrow stem cells grafted to striatum and hippocampus of impaired aged rats: Functional and therapeutic considerations
    • Fernandez CI, Alberti E, Mendoza Y, Martinez L, Collazo J, Rosillo JC, Bauza JY (2004). Motor and cognitive recovery induced by bone marrow stem cells grafted to striatum and hippocampus of impaired aged rats: Functional and therapeutic considerations. Ann N Y Acad Sci, 1019:48-52.
    • (2004) Ann N Y Acad Sci , vol.1019 , pp. 48-52
    • Fernandez, C.I.1    Alberti, E.2    Mendoza, Y.3    Martinez, L.4    Collazo, J.5    Rosillo, J.C.6    Bauza, J.Y.7
  • 87
    • 33846518931 scopus 로고    scopus 로고
    • Radiation response of neural precursor cells
    • Fike JR, Rola R, Limoli CL (2007). Radiation response of neural precursor cells. Neurosurg Clin N Am, 18:115-127, x.
    • (2007) Neurosurg Clin N Am , vol.18 , pp. 115-127
    • Fike, J.R.1    Rola, R.2    Limoli, C.L.3
  • 88
    • 60649107163 scopus 로고    scopus 로고
    • Neural precursor cells and central nervous system radiation sensitivity
    • Fike JR, Rosi S, Limoli CL (2009). Neural precursor cells and central nervous system radiation sensitivity. Semin Radiat Oncol, 19:122-132.
    • (2009) Semin Radiat Oncol , vol.19 , pp. 122-132
    • Fike, J.R.1    Rosi, S.2    Limoli, C.L.3
  • 89
    • 0036735783 scopus 로고    scopus 로고
    • Irradiation induces neural precursor-cell dysfunction
    • Monje ML, Mizumatsu S, Fike JR, Palmer TD (2002). Irradiation induces neural precursor-cell dysfunction. Nat Med, 8:955-962.
    • (2002) Nat Med , vol.8 , pp. 955-962
    • Monje, M.L.1    Mizumatsu, S.2    Fike, J.R.3    Palmer, T.D.4
  • 90
    • 39149122164 scopus 로고    scopus 로고
    • Delayed injection of neural progenitor cells improved spatial learning dysfunction after cerebral ischemia
    • Mochizuki N, Takagi N, Onozato C, Moriyama Y, Takeo S, Tanonaka K (2008). Delayed injection of neural progenitor cells improved spatial learning dysfunction after cerebral ischemia. Biochem Biophys Res Commun, 368:151-156.
    • (2008) Biochem Biophys Res Commun , vol.368 , pp. 151-156
    • Mochizuki, N.1    Takagi, N.2    Onozato, C.3    Moriyama, Y.4    Takeo, S.5    Tanonaka, K.6
  • 91
    • 8444246829 scopus 로고    scopus 로고
    • Hepatocyte growth factor improved learning and memory dysfunction of microsphere-embolized rats
    • Date I, Takagi N, Takagi K, Kago T, Matsumoto K, Nakamura T, Takeo S (2004). Hepatocyte growth factor improved learning and memory dysfunction of microsphere-embolized rats. J Neurosci Res, 78:442-453.
    • (2004) J Neurosci Res , vol.78 , pp. 442-453
    • Date, I.1    Takagi, N.2    Takagi, K.3    Kago, T.4    Matsumoto, K.5    Nakamura, T.6    Takeo, S.7
  • 92
    • 42749090554 scopus 로고    scopus 로고
    • Injection of neural progenitor cells improved learning and memory dysfunction after cerebral ischemia
    • Mochizuki N, Takagi N, Kurokawa K, Onozato C, Moriyama Y, Tanonaka K, Takeo S (2008). Injection of neural progenitor cells improved learning and memory dysfunction after cerebral ischemia. Exp Neurol, 211:194-202.
    • (2008) Exp Neurol , vol.211 , pp. 194-202
    • Mochizuki, N.1    Takagi, N.2    Kurokawa, K.3    Onozato, C.4    Moriyama, Y.5    Tanonaka, K.6    Takeo, S.7
  • 93
    • 0031587271 scopus 로고    scopus 로고
    • Recovery of spatial learning by grafts of a conditionally immortalized hippocampal neuroepithelial cell line into the ischaemia-lesioned hippocampus
    • Sinden JD, Rashid-Doubell F, Kershaw TR, Nelson A, Chadwick A, Jat PS, Noble MD, Hodges H, Gray JA (1997). Recovery of spatial learning by grafts of a conditionally immortalized hippocampal neuroepithelial cell line into the ischaemia-lesioned hippocampus. Neuroscience, 81:599-608.
    • (1997) Neuroscience , vol.81 , pp. 599-608
    • Sinden, J.D.1    Rashid-Doubell, F.2    Kershaw, T.R.3    Nelson, A.4    Chadwick, A.5    Jat, P.S.6    Noble, M.D.7    Hodges, H.8    Gray, J.A.9
  • 96
    • 47249123640 scopus 로고    scopus 로고
    • Intrahippocampal transplantation of transgenic neural precursor cells overexpressing interleukin-1 receptor antagonist blocks chronic isolation-induced impairment in memory and neurogenesis
    • Ben Menachem-Zidon O, Goshen I, Kreisel T, Ben Menahem Y, Reinhartz E, Ben Hur T, Yirmiya R (2008). Intrahippocampal transplantation of transgenic neural precursor cells overexpressing interleukin-1 receptor antagonist blocks chronic isolation-induced impairment in memory and neurogenesis. Neuropsychopharmacology, 33:2251-2262.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2251-2262
    • Ben Menachem-Zidon, O.1    Goshen, I.2    Kreisel, T.3    Ben Menahem, Y.4    Reinhartz, E.5    Ben Hur, T.6    Yirmiya, R.7
  • 98
    • 58249088720 scopus 로고    scopus 로고
    • Long-term functional restoration by neural progenitor cell transplantation in rat model of cognitive dysfunction: Co-transplantation with olfactory ensheathing cells for neurotrophic factor support
    • Srivastava N, Seth K, Khanna VK, Ansari RW, Agrawal AK (2009). Long-term functional restoration by neural progenitor cell transplantation in rat model of cognitive dysfunction: Co-transplantation with olfactory ensheathing cells for neurotrophic factor support. Int J Dev Neurosci, 27:103-110.
    • (2009) Int J Dev Neurosci , vol.27 , pp. 103-110
    • Srivastava, N.1    Seth, K.2    Khanna, V.K.3    Ansari, R.W.4    Agrawal, A.K.5
  • 99
    • 0032751115 scopus 로고    scopus 로고
    • Primary ca1 and conditionally immortal mhp36 cell grafts restore conditional discrimination learning and recall in marmosets after excitotoxic lesions of the hippocampal ca1 field
    • Virley D, Ridley RM, Sinden JD, Kershaw TR, Harland S, Rashid T, French S, Sowinski P, Gray JA, Lantos PL, Hodges H (1999). Primary ca1 and conditionally immortal mhp36 cell grafts restore conditional discrimination learning and recall in marmosets after excitotoxic lesions of the hippocampal ca1 field. Brain, 122 (Pt 12):2321-2335.
    • (1999) Brain , vol.122 , pp. 2321-2335
    • Virley, D.1    Ridley, R.M.2    Sinden, J.D.3    Kershaw, T.R.4    Harland, S.5    Rashid, T.6    French, S.7    Sowinski, P.8    Gray, J.A.9    Lantos, P.L.10    Hodges, H.11
  • 100
    • 77954824190 scopus 로고    scopus 로고
    • Medial ganglionic eminence-derived neural stem cell grafts ease spontaneous seizures and restore gdnf expression in a rat model of chronic temporal lobe epilepsy
    • Waldau B, Hattiangady B, Kuruba R, Shetty AK (2010). Medial ganglionic eminence-derived neural stem cell grafts ease spontaneous seizures and restore gdnf expression in a rat model of chronic temporal lobe epilepsy. Stem Cells
    • (2010) Stem Cells
    • Waldau, B.1    Hattiangady, B.2    Kuruba, R.3    Shetty, A.K.4
  • 101
    • 34347385652 scopus 로고    scopus 로고
    • Aav-mediated delivery of bdnf augments neurogenesis in the normal and quinolinic acid-lesioned adult rat brain
    • Henry RA, Hughes SM, Connor B (2007). Aav-mediated delivery of bdnf augments neurogenesis in the normal and quinolinic acid-lesioned adult rat brain. Eur J Neurosci, 25:3513-3525.
    • (2007) Eur J Neurosci , vol.25 , pp. 3513-3525
    • Henry, R.A.1    Hughes, S.M.2    Connor, B.3
  • 102
    • 72949096531 scopus 로고    scopus 로고
    • Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis
    • Taliaz D, Stall N, Dar DE, Zangen A (2010). Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis. Mol Psychiatry, 15:80-92.
    • (2010) Mol Psychiatry , vol.15 , pp. 80-92
    • Taliaz, D.1    Stall, N.2    Dar, D.E.3    Zangen, A.4
  • 103
    • 77649190522 scopus 로고    scopus 로고
    • Acute and gradual increases in bdnf concentration elicit distinct signaling and functions in neurons
    • Ji Y, Lu Y, Yang F, Shen W, Tang TT, Feng L, Duan S, Lu B (2010). Acute and gradual increases in bdnf concentration elicit distinct signaling and functions in neurons. Nat Neurosci, 13:302-309.
    • (2010) Nat Neurosci , vol.13 , pp. 302-309
    • Ji, Y.1    Lu, Y.2    Yang, F.3    Shen, W.4    Tang, T.T.5    Feng, L.6    Duan, S.7    Lu, B.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.