Ex vivo nerve growth factor gene transfer to the basal forebrain in presymptomatic middle-aged rats prevents the development of cholinergic neuron atrophy and cognitive impairment during aging

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 4, 1998, Pages 1858-1863

  Martínez Serrano, Alberto ^a,b,c   Björklund, Anders ^a  

^a LUND UNIVERSITY   (Sweden)

^b CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^c UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Alzheimer's disease; Gene therapy; Memory; p75(NTR)

Indexed keywords

ACETYLCHOLINE; NERVE GROWTH FACTOR;

ADOLESCENT; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN PROTECTION; CELL IMMORTALIZATION; CHOLINERGIC NERVE CELL; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; FOREBRAIN; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; INTRACEREBRAL DRUG ADMINISTRATION; LEARNING; MAZE TEST; NONHUMAN; OLIVARY NUCLEUS; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; BEHAVIOR, ANIMAL; CHOLINERGIC FIBERS; COGNITION; FEMALE; GENE TRANSFER TECHNIQUES; NERVE GROWTH FACTORS; NEURODEGENERATIVE DISEASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, NERVE GROWTH FACTOR; RECEPTORS, NERVE GROWTH FACTOR; STEM CELL TRANSPLANTATION;

ANIMALIA;

EID: 0032539698     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.4.1858     Document Type: Article

References (48)

1. Dunnett, S. B. & Fibiger, H. C. (1993) Prog. Brain Res. 98, 413-420.
2. Finch, C. E. (1993) Trends Neurosci. 16, 104-110.
3. Gallagher, M. & Colombo, P. (1995) Gurr. Opin. Neurobiol. 5, 161-168.
4. Everitt, B. J. & Robbins, T. W. (1997) Annu. Rev. Psychol. 48, 649-684.
5. Fischer, W., Wictorin, K., Björklund, A., Williams, L. R., Varon, S. & Gage, F. H. (1987) Nature (London) 329, 65-68.
6. Fischer, W., Björklund, A., Chen, K. & Gage, F. H. (1991) J. Neurosci. 11, 1889-1906.
7. Fischer, W., Sirevaag, A., Wiegand, S. J., Lindsay, R. M. & Björklund, A. (1994) Proc. Natl. Acad. Sci. USA 91, 8607-8611.
8. Markowska. A. L., Koliatsos, V. E., Breckler, S. J., Price. D. L. & Olton, D. S. (1994) J. Neurosci. 14, 4815-4824.
9. Bäckman, C., Rose, G. M., Hoffer, B. J., Henry, M. A., Bartus, R. T., Friden, P. & Granholm, A. C. (1996) J. Neurosci. 16, 5437-5442.
10. Frick, K. M., Price, D. L., Koliatsos, V. E. & Markowska. A. L. (1997) J. Neurosci. 17, 2543-2550.
11. Lindsay, R. M., Wiegand, S. J., Altar, C. A. & Distefano, P. S. (1994) Trends Neurosci. 17, 182-190.
12. Lewin, G. R. & Barde, Y.-A. (1996) Annu. Rev. Neurosci. 19, 289-317.
13. Rylett, R. J. & Williams, L. R. (1994) Trends Neurosci. 11, 486-490.
14. Hellweg, R., Fischer, W., Hock, W., Gage, F. H., Björklund, A. & Thoenen, H. (1990) Brain Res. 537, 123-130.
15. Crutcher, K. A. & Weingartner, K. (1991) Neurobiol. Aging 12, 449-454.
16. Williams, L. R. (1991) Exp. Neurol 113, 31-37.
17. Lewin, G. R. & Mendell, L. M. (1993) Trends Neurosci. 16, 353-359.
18. Chen, K. S. & Gage, F. H. (1995) J. Neurosci. 15, 2819-2825.
19. Martinez-Serrano, A., Fischer, W. & Björklund, A. (1995) Neuron 15, 473-484.
20. Martinez-Serrano, A., Fischer, W., Söderstrom, S., Ebendal, T. & Björklund, A. (1996) Proc. Natl. Acad. Sci. USA 93, 6355-6360.
21. Lindner, M. D., Kearns, C. E., Winn, S. R., Frydel, B. & Emerich, D. F. (1996) Cell Transplant. 5, 205-223.
22. Martinez-Serrano, A., Lundberg, C., Horellou, P., Fischer, W., Bentlage, C., Campbell, K., McKay, R. D. G., Mallet, J. & Björklund, A. (1995) J. Neurosci. 15, 5668-5680.
23. Renfranz, P. J., Cunningham, M. G. & McKay, R. D. G. (1991) Cell 66, 713-729.
24. Leanza, G., Muir, J., Nilsson, O. G., Wiley, R. G., Dunnet, S. B. & Björklund, A. (1996) Eur. J. Neurosci. 8, 1535-1544.
25. Fischer, W., Chen, K. S., Gage, F. H. & Björklund, A. (1992) Neurobiol. Aging 13, 9-23.
26. Winn, S. R., Lindner, M. D., Lee, A., Haggett, G., Francis, J. M. & Emerich, D. F. (1996) Exp. Neurol. 140, 126-138.
27. Pelleymounter, M. A., Cullen, M. J., Baker, M. B., Gollub, M. & Wellman, C. (1996) Mol. Chem. Neuropathol. 29, 211-226.
28. Lundberg, C., Martínez-Serrano, A., Cattaneo, E., McKay, R. D. G. & Björklund, A. (1997) Exp. Neurol. 145, 342-360.
29. Yan, Q., Matheson, C., Sun, J., Radeke, M. J., Feinstein, S. C. & Miller, J. A. (1994) Exp. Neurol. 127, 23-36.
30. Krewson, C. E., Klarman, M. L. & Saltzman, W. M. (1995) Brain Res. 680, 196-206.
31. Krewson, C. E. & Saltzman, W. M. (1996) Brain Res. 727, 169-181.
32. Knusel, B. N., Kaplan, D. R. & Hefti, F. (1996) Exp. Neurol. 139, 121-130.
33. Kordower, J. H., Charles, V., Bayer, R., Bartus, R. T., Putney, S., Walus, L. R. & Friden, P. M. (1994) Proc. Natl. Acad. Sci. USA 91, 9077-9080.
34. McMahon, S. B. & Priestley, J. V. (1995) Curr. Opin. Neurobiol. 5, 616-624.
35. Torcia, M., Bracci-Laudiero, L., Lucibello, M., Nencioni, L., Labardi, D., Rubartelli, A., Cozzolino, F., Aloe, L. & Garaci, E. (1996) Cell 85, 345-356.
36. Waite, J. J., Chen, A. D., Wardlow, M. L., Wiley, R. G., Lappi, A. D. & Tal, L. J. (1995) Neuroscience 65, 463-476.
37. Leanza, G., Nilsson, O. G., Wiley, R. G. & Björklund, A. (1995) Eur. J. Neurosci. 7, 329-343.
38. Torres, E. M., Perry, T. A., Blokland, A., Wilkinson, L. S., Wiley, R. G., Lappi, D. A. & Dunnett, S. B. (1994) Neuroscience 63, 95-122.
39. Baxter, M. G., Bucci, D. J., Sobel, T. J., Williams, M. J., Gorman, L. K. & Gallager, M. (1996) Neuroreport 7, 1417-1420.
40. McMahan, R. W., Sobel, T. J. & Baxter, M. G. (1997) Hippocampus 7, 130-136.
41. Mervis, R. F., Pope, D., Lewis, R., Dvorak, R. M. & Williams, L. R. (1991) Ann. N. Y. Acad. Sci. 640, 95-101.
42. Patterson, P. H. (1995) Curr. Opin. Neurobiol. 5, 642-646.
43. Perry, V. H., Bell, M. D., Brown, H. C. & Matyszak, M. K. (1995) Curr. Opin. Neurobiol. 5, 636-641.
44. Martínez-Serrano, A. & Björklund, A. (1996) J. Neurosci. 16, 4604-4616.
45. Levi-Montalcini, R., Skaper, S. D., Dal Toso, R., Petrelli, L. & Leon, A. (1996) Trends Neurosci. 19, 514-520.
46. Galpern, W. R., Matthews, R. T., Beal, M. F. & Isacson, O. (1996) Neuroreport 7, 2639-2642.
47. Cooper, J. D., Lindholm, D. & Sofroniew, M. V. (1994) Neuroscience 62, 625-629.
48. Mufson, E. J., Li, J. M., Sobreviela, T. & Kordower, J. H. (1996) Neuroreport 8, 25-29.