Cerebellar damage impairs executive control and monitoring of movement generation

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Brunamonti, Emiliano ^a   Chiricozzi, Francesca R ^b,c   Clausi, Silvia ^b,c   Olivito, Giusy ^b,c   Giusti, Maria Assunta ^a   Molinari, Marco ^c   Ferraina, Stefano ^a   Leggio, Maria ^b,c  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BASAL GANGLION; BEHAVIOR; BRAIN CORTEX; BRAIN FUNCTION; CEREBELLUM INJURY; CEREBELLUM NUCLEUS; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; EXECUTIVE FUNCTION; FEMALE; HUMAN; IMAGE ANALYSIS; IMAGE PROCESSING; IMAGE QUALITY; MALE; MOTOR PERFORMANCE; PSYCHOMETRY; RESPONSE TIME; TASK PERFORMANCE; THALAMUS;

BEHAVIOR; CASE-CONTROL STUDIES; CEREBELLUM; DEMOGRAPHY; EXECUTIVE FUNCTION; FEMALE; HUMANS; MALE; MIDDLE AGED; MOVEMENT; NEURAL INHIBITION; NEUROPSYCHOLOGICAL TESTS; REACTION TIME; TASK PERFORMANCE AND ANALYSIS;

EID: 84897513879     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085997     Document Type: Article

References (80)

1. Reichenberg A (2010) The assessment of neuropsychological functioning in schizophrenia. Dialogues Clin Neurosci 12: 383-92.
2. Verbruggen F, Logan GD (2008) Response inhibition in the stop-signal paradigm. Trends in Cognitive Sciences 12: 418-424.
3. Alvarez JA, Emory E (2006) Executive function and the frontal lobes: A meta-analytic review. Neuropsychology Review 16: 17-42. (Pubitemid 43954075)
4. Aron A, Robbins T, Poldrack R (2004) Inhibition and the right inferior frontal cortex. Trends in Cognitive Science 8: 170-177. (Pubitemid 38429927)
5. Rubia K, Smith AB, Brammer MJ, Taylor E (2003) Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection. Neuroimage 20: 351-8. (Pubitemid 37188523)
6. Garavan H, Ross TJ, Murphy K, Roche RA, Stein EA (2002) Dissociable executive functions in the dynamic control of behavior: inhibition, error detection, and correction. Neuroimage 17: 1820-29. (Pubitemid 36062772)
7. Aron AR, Poldrack RA, Wise SP (2009) Cognition: Basal Ganglia Role. In: Squire LR editor. Encyclopedia of Neuroscience, volume 2. Oxford: Academic Press. pp. 1069-1077.
8. Li CS, Yan P, Sinha R, Lee TW (2008) Subcortical processes of motor response inhibition during a stop signal task. Neuroimage 41: 1352-63.
9. Chevrier AD, Noseworthy MD, Schachar R (2007) Dissociation of response inhibition and performance monitoring in the stop signal task using event-related fMRI. Human Brain Mapping 28: 1347-58. (Pubitemid 350234186)
10. Aron AR, Poldrack RA (2006) Cortical and subcortical contributions to Stop signal response inhibition: role of the subthalamic nucleus. The Journal of Neuroscience 26: 2424-33. (Pubitemid 44699002)
11. Ide JS, Li CS (2011) A cerebellar thalamic cortical circuit for error-related cognitive control. Neuroimage 54: 455-64.
12. Bostan AC, Strick PL (2010) The cerebellum and basal ganglia are interconnected. Neuropsychology Review 20: 261-70.
13. Miall RC (1998). The cerebellum, predictive control and motor coordination. Novartis Found Symp 218: 272-84.
14. Schlerf J, Ivry RB, Diedrichsen J (2012) Encoding of sensory prediction errors in the human cerebellum. J Neurosci 32: 4913-22.
15. Wolpert DM, Miall RC, Kawato M (1998) Internal models in the cerebellum. Trends Cogn Sci 2: 338-47. (Pubitemid 28396569)
16. Falkenstein M, Hielscher H, Dziobek I, Schwarzenau P, Hoormann J, et al. (2001) Action monitoring, error detection, and the basal ganglia: an ERP study. Neuroreport 12: 157-61. (Pubitemid 32099047)
17. Falkenstein M, Hoormann J, Christ S, Hohnsbein J (2000) ERP components on reaction errors and their functional significance: a tutorial. Biological Psychology 51(2-3): 87-107. (Pubitemid 30109225)
18. Beste C, Saft C, Andrich J, Gold R, Falkenstein M (2006) Error processing in Huntington's disease. PLoS One 1: e86.
19. Ullsperger M, von Cramon DY (2006) The role of intact frontostriatal circuits in error processing. Journal of Cognitive Neuroscience 18: 651-64. (Pubitemid 43763864)
20. Neau JP, Arroyo-Anllo E, Bonnaud V, Ingrand P, Gil R (2000) Neuropsychological disturbances in cerebellar infarcts. Acta Neurol Scand 102: 363-52.
21. Tanaka H, Harada M, Arai M, Hirata K (2003) Cognitive dysfunction in cortical cerebellar atrophy correlates with impairment of the inhibitory system. Neuropsychobiology 47: 206-11. (Pubitemid 36735234)
22. Tu PC, Yang TH, Kuo WJ, Hsieh JC, Su TP (2006) Neural correlates of antisaccade deficits in schizophrenia, an fMRI study. Journal of Psychiatric Research 40: 606-61.
23. Rubia K, Smith AB, Taylor E, Brammer M (2007) Linear age-correlated functional development of right inferior fronto-striato-cerebellar networks during response inhibition and anterior cingulate during error-related processes. Hum Brain Mapp 28: 1163-77. (Pubitemid 350077481)
24. Thoma P, Koch B, Heyder K, Schwarz M, Daum I (2008) Subcortical contributions to multitasking and response inhibition. Behavioral Brain Research 194: 214-22.
25. Schall JD, Godlove DC (2012) Current advances and pressing problems in studies of stopping. Curr Opin Neurobiol 22: 1012-21.
26. Rubia K, Overmeyer S, Taylor E, Brammer M, Williams SC, et al. (1999) Hypofrontality in attention deficit hyperactivity disorder during higher-order motor control: a study with functional MRI. Am J Psychiatry 156: 891-6. (Pubitemid 29260344)
27. Habas C (2010) Functional imaging of deep cerebellar nuclei: a review. Cerebellum 9: 22-8.
28. Tedesco AM, Chiricozzi FR, Clausi S, Lupo M, Molinari M, et al. (2011) The cerebellar cognitive profile. Brain 134: 3669-83.
29. Rey A (1958) L'examen clinique en psychologie. Paris: Presses Universiteries de France.
30. Carlesimo GA, Marfia GA, Loasses A, Caltagirone C (1996) Perceptual and conceptual components in implicit and explicit stem completion. Neuropsychologia 34: 785-92. (Pubitemid 26202640)
31. Corsi PM (1972) Human memory and the medial temporal regions of the brain. Dissert Abst Int 34: 891B.
32. Raven JC (1949) Sets A, Ab, B: Board and Book forms. Progressive matrices London: Lewis.
33. Gainotti G, Miceli G, Caltagirone C (1977) Constructional apraxia in left brain-damage patients: a planning disorders? Cortex 13: 109-18. (Pubitemid 8147959)
34. Villa G, Gainotti G, De Bonis C, Marra C (2008) Double dissociation between temporal and spatial pattern processing in patients with frontal and parietal damage. Cortex 26: 399-407.
35. Borkowsky JG, Benton AL, Spreen O (1967) Word fluency and brain-damage. Neuropsychologia 5:135-140.
36. Leggio MG, Silveri MC, Petrosini L, Molinari M (2000) Phonological grouping is specifically affected in cerebellar patients: a verbal fluency study. Journal of Neurology, Neurosurgery and Psychiatry 69: 102-6. (Pubitemid 30410423)
37. Leggio MG, Tedesco AM, Chiricozzi FR, Clausi S, Orsini A, et al (2008) Cognitive sequencing impairment in patients with focal or atrophic cerebellar damage. Brain 131:1332-43.
38. Molinari M, Petrosini L, Misciagna S, Leggio MG (2004) Visuospatial abilities in cerebellar disorders. Journal of Neurology Neurosurgery and Psychiatry 75: 235-40. (Pubitemid 38183530)
39. Restuccia D, Della Marca G, Valeriani M, Leggio MG, Molinari M (2007) Cerebellar damage impairs detection of somatosensory input changes. A somatosensory mismatch-negativity study. Brain 130: 276-87. (Pubitemid 46026242)
40. Silveri MC, Di Betta AM, Filippini V, Leggio MG, Molinari M (1998) Verbal short-term store-rehearsal system and the cerebellum. Evidence from a patient with a right cerebellar lesion. Brain 121: 2175-87. (Pubitemid 28497914)
41. Justus T. The cerebellum and English grammatical morphology: evidence from production, comprehension, and grammaticality judgments (2004) Journal of Cognitive Neuroscience 16: 1115-30. (Pubitemid 39274441)
42. Appollonio IM, Grafman J, Schwartz V, Massaquoi S, Hallett M (1993) Memory in patients with cerebellar degeneration. Neurology 43: 1536-44. (Pubitemid 23230539)
43. Mugler JPD, Brookrman JR (1990). Three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP RAGE). Magn Reson Med 15: 152-157.
44. Brett M, Leff AP, Rorden C, Ashburner J (2001) Spatial normalization of brain images with focal lesions using cost function masking. Neuroimage 14: 486-500. (Pubitemid 32709562)
45. Schmahmann JD, Dojon J, Toga AW, Petrides M, Evans AC (2000) MRI atlas of the human cerebellum. San Diego: Academic Press.
46. Dimitrova A, Zeljko D, Schwarze F, Maschke M, Gerwig M, et al. (2006) Probabilistic 3D MRI atlas of the human cerebellar dentate/interposed nuclei. Neuroimage 30: 12-25. (Pubitemid 43245600)
47. Band GP, van der Molen MW, Logan GD (2003) Horse-race model simulations of the stop-signal procedure. Acta Psychol (Amst) 112:105-142. (Pubitemid 36881099)
48. Brunamonti E, Pani P, Papazachariadis O, Onorati P, Albertini G, et al. (2011) Cognitive control of movement in Down syndrome. Research in Developmental Disabililities 32: 1792-7.
49. Mirabella G, Pani P, Ferraina S (2009) The presence of visual gap affects the duration of stopping process. Exp Brain Res 192: 199-209.
50. Logan GD (1984) On the ability to inhibit thought and action: A users' guide to the stop signal paradigm. In: Dagenbach D, Carr TH, editors. Inhibitory Processes in Attention, Memory, and Language. San Diego: Academic Press. p 189-239.
51. Brunamonti E, Ferraina S, Paré M (2012) Controlled movement processing: Evidence for a common inhibitory control of finger, wrist, and arm movements. Neuroscience 215: 69-78.
52. Braver TS (2012) The variable nature of cognitive control: a dual mechanisms framework. Trends Cogn Sci (Regul. Ed.) 16: 106-113.
53. Duque J, Thonnard JL, Vandermeeren Y, Sébire G, Cosnard G, Olivier E (2003) Correlation between impaired dexterity and corticospinal tract dysgenesis in congenital hemiplegia. Brain 126: 732-47. (Pubitemid 36240873)
54. Zar J (2009) Biostatistical Analysis, 4th edition, Prentice-Hall.
55. Mirabella G, Pani P, Ferraina S (2011) Neural correlates of cognitive control of reaching movements in the dorsal premotor cortex of rhesus monkeys. Journal of Neurophysiology 106: 1454-1466.
56. Marcos E, Pani P, Brunamonti E, Deco G, Ferraina S, Verschure P (2013) Neural variability in premotor cortex is modulated by trial history and predicts behavioral performance. Neuron 78: 249-255.
57. Duann JR, Ide JS, Luo X, Li CS (2009) Functional connectivity delineates distinct roles of the inferior frontal cortex and presupplementary motor area in stop signal inhibition. The Journal of Neuroscience 29: 10171-9.
58. Nambu A, Takada M, Inase M, Tokunoz H. (1996) Dual somatotopical representations in the primate subthalamic nucleus: evidence for ordered but reversed body-map transformations from the primary motor cortex and the supplementary motor area. The Journal of Neuroscience 16: 2671-2683. (Pubitemid 26122683)
59. Brunia CHM (2003) How is stopping realized? In: Ullsperger M, Falkenstein M, editors. Errors, Conflicts, and the Brain. Current Opinions on Performance Monitoring. Leipzig: MPI of Cognitive Neuroscience.
60. Mink JW(1996) The basal ganglia: focused selection and inhibition of competing motor programs. Progress in Neurobiology 50: 381-425.
61. Nambu A, Tokuno H, Takada M (2002) Functional significance of the cortico-subthalamo-pallidal 'hyperdirect' pathway. Neuroscience Research 43: 111-7. (Pubitemid 34627041)
62. Alexander GE, Crutcher MD (1990) Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends in Neuroscience 13: 266-71. (Pubitemid 20193456)
63. Holmes G (1939) The cerebellum of man. Brain 62: 1-30.
64. Luciani L (1891) Il cervelletto: nuove studi di fisiologia normale e patologica. Firenze: Le Monnier.
65. Ito M (1984) The cerebellum and neural control. New York: Raven.
66. Li CS, Huang C, Constable RT, Sinha R (2006) Gender differences in the neural correlates of response inhibition during a stop signal task. Neuroimage 32: 1918-29. (Pubitemid 44332288)
67. Li CS, Zhang S, Duann JR, Yan P, Sinha R, Mazure CM (2009) Gender Differences in Cognitive Control: an Extended Investigation of the Stop Signal Task. Brain Imaging Behav 3: 262-276.
68. Molinari M, Leggio MG, Solida A, Ciorra R, Misciagna S, et al. (1997) Cerebellum and procedural learning: evidence from focal cerebellar lesions. Brain 120: 1753-62. (Pubitemid 27443051)
69. Molinari M, Leggio MG, Filippini V, Gioia MC, Cerasa A, et al. (2005) Sensorimotor transduction of time information is preserved in subjects with cerebellar damage. Brain Res Bull 67: 448-58. (Pubitemid 41416740)
70. Van Mier HI, Tempel LW, Perlmutter JS, Raichle ME, Petersen SE (1998) Changes in brain activity during motor learning measured with PET: effects of hand of performance and practice. J Neurophysiol 80: 2177-2199. (Pubitemid 28489142)
71. Van Mier HI, Petersen SE (2002) Role of the cerebellum in motor cognition. Ann N Y Acad Sci 978: 334-53. (Pubitemid 36127121)
72. Willemssen R, Müller T, Schwarz M, Hohnsbein J, Falkenstein M (2008) Error processing in patients with Parkinson's disease: the influence of medication state. Journal of Neural Transmission 115: 461-8.
73. Ebner TJ, Pasalar S (2008) Cerebellum predicts the future motor state. Cerebellum, 7:583-8.
74. Doya K (2000) Complementary roles of basal ganglia and cerebellum in learning and motor control. Current Opinion in Neurobiology 10: 732-9.
75. Blakemore SJ, Frith CD, Wolpert DM (2001) The cerebellum is involved in predicting the sensory consequences of action. Neuroreport 12: 1879-84. (Pubitemid 32553701)
76. Imamizu H, Miyauchi S, Tamada T, Sasaki Y, Takino R, et al. (2000) Human cerebellar activity reflecting an acquired internal model of a new tool. Nature 403: 192-5. (Pubitemid 30050961)
77. Courchesne E, Allen G (1997) Prediction and preparation, fundamental functions of the cerebellum. Learning and Memory 4: 1-35.
78. Ilg W, Giese MA, Gizewski ER, Schoch B, Timmann D (2008) The influence of focal cerebellar lesions on the control and adaptation of gait. Brain 131: 2913- 27.
79. Clausi S, Bozzali M, Leggio MG, Di Paola M, Hagberg GE, et al. (2009) Quantification of gray matter changes in the cerebral cortex after isolated cerebellar damage: a voxel-based morphometry study. Neuroscience 162: 827- 35.
80. Diedrichsen J, Maderwald S, Küper M, Thürling M, Rabe K, et al. (2011) Imaging the deep cerebellar nuclei: a probabilistic atlas and normalization procedure. Neuroimage 54: 1786-94.