Hypofrontality in attention deficit hyperactivity disorder during higher-order motor control: A study with functional MRI

American Journal of Psychiatry

Volumn 156, Issue 6, 1999, Pages 891-896

  Rubia, Katya ^a   Overmeyer, Stephan ^b   Taylor, Eric ^b   Brammer, Michael ^b   Williams, Steve C R ^b   Simmons, Andrew ^b   Bullmore, Edward T ^b  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE; ARTICLE; ATTENTION DEFICIT DISORDER; CLINICAL ARTICLE; CONTROLLED STUDY; EXPERIMENTAL TEST; HUMAN; INTELLIGENCE QUOTIENT; MALE; MOTOR CONTROL; NUCLEAR MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; PRIORITY JOURNAL; SCHOOL CHILD; SEX; TASK PERFORMANCE;

EID: 0033014403     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.156.6.891     Document Type: Article

References (41)

1. Barkley RA: Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull 1997; 121:65-94
2. Carte ET, Nigg JT, Hinshaw SP: Neuropsychological functioning, motor speed, and language processing in boys with and without ADHD. J Abnorm Child Psychol 1996; 24:481-498
3. Trommer BL, Hoeppner JAB, Lorber R, Armstrong KJ: The go-no-go paradigm in attention deficit disorder. Ann Neurol 1988; 24:610-614
4. Shue KL, Douglas VI: Attention deficit hyperactivity disorder and the frontal lobe syndrome. Brain Cogn 1992; 20:104-124
5. Schachar R, Logan GD: Impulsivity and inhibitory control in normal development and childhood psychopathology. Dev Psychol 1990; 26:710-720
6. Rubia K, Oosterlaan J, Sergeant JA, Brandeis D, van Leeuwen T: Inhibitory dysfunction in hyperactive boys. Behav Brain Res 1998; 94:25-32
7. Gorenstein EE, Mammato CA, Sandy JM: Performance of inattentive-overactive children on selected measures of prefrontal-type function. J Clin Psychol 1989; 45:619-634
8. Grodzinsky GM, Diamond R: Frontal lobe functioning in boys with attention-deficit hyperactivity disorder. Developmental Neuropsychology 1992; 8:427-445
9. Swanson JM, Sergeant JA, Taylor E, Sonuga-Barke EJ, Cantwell DP: Attention-deficit hyperactivity disorder and hyperkinetic disorder. Lancet 1998; 351:429-433
10. Castellanos FX, Giedd JN, Marsh WL, Hamburger SD, Vaituzis AC, Dickstein DP, Sarfatti SE, Vauss YC, Snell JW, Lange NL, Kaysen D, Krain AL, Ritchie GF, Rajapakse JC, Rapoport JL: Quantitative brain magnetic resonance imaging in attention-deficit hyperactivity disorder. Arch Gen Psychiatry 1996; 53:607-616
11. Filipek PA, Semrud-Clikeman M, Steingard RJ, Renshaw PF, Kennedy DN, Biederman J: Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder and normal controls. Neurology 1996; 48:589-601
12. Casey BJ, Trainor R, Giedd J, Vauss Y, Vaituzis CK, Hamburger S, Kozuch P, Rapoport JL: The role of the anterior cingulate in automatic and controlled processes, a developmental neuroanatomical study. Dev Psychobiol 1997; 30:61-69
13. Aylward EH, Reiss AL, Reader MJ, Singer HS, Brown JE, Denckla MB: Basal ganglia volumes in children with attention deficit-hyperactivity disorder. J Child Neurol 1996; 11:112-115
14. Hynd GW, Semrud-Clikeman M, Lorys AR, Novey ES, Eliopulos D: Brain morphology in developmental dyslexia and attention deficit disorder/hyperactivity. Arch Neurol 1990; 47:919-922
15. Zametkin AJ, Nordahl TE, Gross M, King AC, Demple WE, Rumsey J, Hamburger S, Cohen RM: Cerebral glucose metabolism in adults with hyperactivity of childhood onset. N Engl J Med 1990; 323:1361-1366
16. Zametkin AJ, Liebenauer LL, Fitzgerald GA, King AC, Minkunas DV, Herscovitch P, Yamada EM, Cohen RM: Brain metabolism in teenagers with attention deficit hyperactivity disorder. Arch Gen Psychiatry 1993; 50:333-340
17. Lou H, Henriksen L, Bruhn P, Borner H, Nielson JB: Striatal dysfunction in attention deficit and hyperkinetic disorder. Arch Neurol 1989; 46:48-52
18. Steinberg B, Laughlin T, Lou H, Andresen J, Friberg L: The striatum in a putative cerebral network activated by verbal awareness in normal and ADHD children (abstract). Neuroimage 1997; 5(April suppl):S309
19. Sieg KG, Gaffney GR, Preston DF, Hellings JA: SPECT brain imaging abnormalities in attention deficit hyperactivity disorder. Clin Nucl Med 1995; 20:55-60
20. Brandeis D, van Leewen TH, Rubia K, Vitacco D, Steger J, Pascual-Marqui RD, Steinhausen H-CH: Neuroelectric mapping reveals precursor of stop failures in children with attention deficits. Behav Brain Res 1998; 94:25-32
21. Rubia K, Overmeyer S, Taylor E, Brammer M, Bullmore ET, Williams S, Simmons A, Andrew C: Functional neuroanatomy of motor inhibition using fMRI (abstract). Neuroimage 1997; 5(April suppl):S111
22. Rubia K, Overmeyer S, Taylor E, Brammer M, Williams S, Simmons A, Andrew C, Bullmore ET: Prefrontal involvement in "temporal bridging" and timing movement. Neuropsychologia 1998; 36:1283-1293
23. Seidman LJ, Biederman J, Faraone SV, Weber W, Ouellette C: Toward defining a neuropsychology of attention deficit-hyperactivity disorder: performance of children and adolescents from a large clinically referred sample. J Consult Clin Psychol 1997; 65:150-160
24. Soper HV, Satz P, Orsini DL, Van Gorp WG, Green MF: Handedness distribution in a residential population with severe or profound mental retardation. Am J Ment Defic 1987; 92:94-102
25. Taylor E, Schachar R, Thorley G, Wieselberg M: Conduct disorder and hyperactivity, I: separation of hyperactivity and antisocial conduct in British child psychiatric patients. Br J Psychiatry 1986; 149:760-767
26. Conners CK: A teacher rating scale for use in drug studies with children. Am J Psychiatry 1969; 126:884-888
27. Taylor E, Chadwick O, Heptinstall E, Danckaerts M: Hyperactivity and conduct problems as risk factors for adolescent development. J Am Acad Child Adolesc Psychiatry 1996; 35: 1213-1226
28. Raven JC: Guide to the Standard Progressive Matrices. London, HK Lewis, 1960
29. Simmons A, Moore E, Williams SCR: Quality control of functional magnetic resonance imaging using automated data analysis and Shewhart charting. Magn Reson Med (in press)
30. Ogawa S, Lee TM, Kay AR, Tank DW: Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci USA 1990; 3:9868-9872
31. Brammer MJ, Bullmore ET, Simmons A, Williams SCR, Grasby PM, Howard RJ, Woodruff PWR, Rabe-Hesketh SR: Generic brain activation mapping in functional magnetic resonance imaging: a non-parametric approach. Magn Reson Imaging 1997; 15:763-770
32. Bullmore ET, Brammer MJ, Williams SCR, Rabe-Hesketh S, Janot N, David AS, Mellers JDC, Howard R, Sham P: Statistical methods of estimation and inference for functional MR image analysis. Magn Reson Med 1996; 35:261-277
33. Talairach J, Tournoux P: Co-Planar Stereotaxic Atlas of the Human Brain. New York, Thieme Medical, 1988
34. Edgington ES: Randomization Tests. New York, Marcel Dekker, 1980
35. Arndt S, Cizadlo T, Andreasen NC, Heckel D, Gold S, O'Leary DS: Tests for comparing images based on randomization and permutation methods. J Cereb Blood Flow 1996; 16:1271-1279
36. Holmes AP, Blair RC, Watson JDG, Ford I: Nonparametric analysis of statistic images from functional mapping experiments. J Cereb Blood Flow Metab 1996; 16:7-22
37. Bullmore ET, Brammer MJ, Rabe-Hesketh S, Curtis VA, Morris RG, Williams SCR, Sharma T, McGuire PK: Methods for diagnosis and treatment of stimulus-correlated motion in generic brain activation studies using fMRl. Hum Brain Mapp 1999; 16:7-22
38. Weinberger DR: Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 1987; 44:660-669
39. Devinsky O, Morrell MJ, Vogt BA: Contributions of anterior cingulate cortex to behaviour. Brain 1995; 118:279-306
40. Jueptner M, Stephan KM, Frith CD, Brooks DJ, Frackowiak RSJ, Passingham RE: Anatomy of motor learning, I: frontal cortex and attention to action. J Neurophysiol 1997; 77:1313-1324
41. Kiefer M, Marzinich F, Weisbrod M, Scherg M, Spitzer M: The time course of brain activation during response inhibition: evidence from event-related potentials in a go/no go task. Neuroreport 1998; 9:765-770