Altered leukotriene B4 metabolism in CYP4F18-deficient mice does not impact inflammation following renal ischemia

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1841, Issue 6, 2014, Pages 868-879

  Winslow, Valeria ^a   Vaivoda, Rachel ^a   Vasilyev, Aleksandr ^a   Dombkowski, David ^a   Douaidy, Karim ^a   Stark, Christopher ^a   Drake, Justin ^b   Guilliams, Evin ^b   Choudhary, Dharamainder ^c   Preffer, Frederic ^a   Stoilov, Ivaylo ^c   Christmas, Peter ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b RADFORD UNIVERSITY   (United States)

^c UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Cytochrome P450; Inflammation; Neutrophil; Hydroxylase

Indexed keywords

ANTIBIOTIC G 418; CRE RECOMBINASE; CYP4F18 PROTEIN; CYTOCHROME P450; GANCICLOVIR; GENOMIC DNA; LEUKOTRIENE B4; NITROGEN; UNCLASSIFIED DRUG; UREA; CYP4F18 PROTEIN, MOUSE; CYP4F3 PROTEIN, HUMAN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SUSPENSION; CONTROLLED STUDY; ENZYME ACTIVITY; EXON; FLOW CYTOMETRY; GENOTYPE; HISTOPATHOLOGY; ICOSANOID METABOLISM; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INFLAMMATION; INTRON; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY PARENCHYMA; LEUKOCYTE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROSOME; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; RNA ISOLATION; TANDEM MASS SPECTROMETRY; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING; ANIMAL; DISEASE MODEL; GENETICS; HUMAN; KIDNEY; KNOCKOUT MOUSE; LEUKOTRIENE B(4); METABOLISM; PATHOLOGY; Ω-HYDROXYLASE;

CYTOCHROME P450; INFLAMMATION; LEUKOTRIENE B(4); NEUTROPHIL; Ω-HYDROXYLASE;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMATION; KIDNEY; LEUKOTRIENE B4; MICE; MICE, KNOCKOUT; NEUTROPHILS; REPERFUSION INJURY;

EID: 84897460339     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.03.002     Document Type: Article

References (53)

1. D.R. Nelson, D.C. Zeldin, S.M.G. Hoffman, L.J. Maltais, H.M. Wain, and D.W. Nebert Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes pseudogenes and alternative-splice variants Pharmacogenetics 14 2004 1 18 (Pubitemid 38183957)
2. A. Kalsotra, and H.W. Strobel Cytochrome P450 4F subfamily: at the crossroads of eicosanoid and drug metabolism Pharmacol. Therapeut. 112 2006 589 611 (Pubitemid 44573491)
3. L. Chen, and J.P. Hardwick Identification of a new P450 subfamily, CYP4F1, expressed in rat hepatic tumors Arch. Biochem. Biophys. 300 1993 18 23 (Pubitemid 23225712)
4. 4 ω-hydroxylase J. Biol. Chem. 268 1993 9376 9380 (Pubitemid 23145985)
5. M. Peters-Golden, and W.R. Henderson Leukotrienes N. Engl. J. Med. 357 2007 1841 1854
6. N. Flamand, P. Mancuso, C.H.C. Serezani, and T.G. Brock Leukotrienes: mediators that have been typecast as villains Cell. Mol. Life Sci. 64 2007 2657 2670 (Pubitemid 350035614)
7. X.-S. Chen, J.R. Sheller, E.N. Johnson, and C.D. Funk Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene Nature 372 1994 179 182 (Pubitemid 24347837)
8. J.L. Goulet, J.N. Snouwaert, A.M. Latour, T.M. Coffman, and B.H. Koller Altered inflammatory responses in leukotriene-deficient mice Proc. Natl. Acad. Sci. U. S. A. 91 1994 12852 12856
9. 4 hydrolase-deficient mice J. Immunol. 163 1999 6810 6819
10. 4 receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis J. Exp. Med. 192 2000 433 438 (Pubitemid 30629168)
11. 4-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis J. Exp. Med. 192 2000 439 446 (Pubitemid 30629169)
12. J.Z. Haeggstrom, and C.D. Funk Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease Chem. Rev. 111 2011 5866 5898
13. R.C. Murphy, and M.A. Gijon Biosynthesis and metabolism of leukotrienes Biochem. J. 405 2007 379 395 (Pubitemid 47172035)
14. Y. Kikuta, E. Kusunose, and M. Kusunose Prostaglandin and leukotriene omega-hydroxylases Prostaglandins Other Lipid Mediat. 68-69 2002 345 362
15. 4 and 12-hydroxy-5,8,10,14-eicosatetraenoic acid to 12-oxo intermediates J. Biol. Chem. 266 1991 20899 20906 (Pubitemid 21908549)
16. 4 12-hydroxydehydrogenase J. Biol. Chem. 271 1996 2844 2850
17. 4 metabolism J. Biol. Chem. 265 1990 16288 16295
18. 4 in human polymorphonuclear leukocytes J. Biol. Chem. 259 1984 10181 10187 (Pubitemid 14067694)
19. 4 20-hydroxylase of human polymorphonuclear leukocytes Proc. Natl. Acad. Sci. U. S. A. 82 1985 2292 2295 (Pubitemid 15064473)
20. 4-induced neutrophil emigration by 20-hydroxy LTB4: implications for the regulation of inflammatory responses Br. J. Pharmacol. 110 1993 423 427 (Pubitemid 23257814)
21. 4 J. Biol. Chem. 281 2006 7189 7196 (Pubitemid 43847485)
22. P. Christmas, J.P. Jones, C.J. Patten, D.A. Rock, Y. Zheng, S.-M. Cheng, B.M. Weber, N. Carlesso, D.T. Scadden, A.E. Rettie, and R.J. Soberman Alternative splicing determines the function of CYP4F3 by switching substrate specificity J. Biol. Chem. 276 2001 38166 38172
23. P. Christmas, N. Carlesso, H. Shang, S.-M. Cheng, B.M. Weber, F.I. Preffer, D.T. Scadden, and R.J. Soberman Myeloid expression of cytochrome P450 4F3 is determined by a lineage-specific alternative promoter J. Biol. Chem. 278 2003 25133 25142 (Pubitemid 37548677)
24. 1 in human liver cells: a regulation of the 20-HETE synthesis J. Lipid Res. 49 2008 2135 2141
25. E. Plee-Gautier, J. Antoun, S. Goulitquer, C. Le Jossic-Corcos, B. Simon, Y. Amet, J.-P. Salaun, and L. Corcos Statins increase cytochrome P450 4F3-mediated eicosanoids production in human liver cells: a PXR dependent mechanism Biochem. Pharmacol. 84 2012 571 579
26. 4 J. Biol. Chem. 265 1990 9131 9139
27. P. Liu, N.A. Jenkins, and N.G. Copeland A highly efficient recombineering-based method for generating conditional knockout mutations Genome Res. 13 2003 476 484 (Pubitemid 36395405)
28. K.R. Maddipati, and S.L. Zhou Stability and analysis of eicosanoids and docosanoids in tissue culture media Prostaglandins Other Lipid Mediat. 94 2011 59 72
29. K.J. Kelly, W.W. Williams, R.B. Colvin, S.M. Meehan, T.A. Springer, J.C. Gutierrez-Ramos, and J.V. Bonventre Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury J. Clin. Invest. 97 1996 1056 1063 (Pubitemid 26070586)
30. F. Preffer, and D. Dombkowski Advances in complex multiparameter flow cytometry technology: applications in stem cell research Cytometry B 76B 2009 295 314
31. F. Tögel, J. Isaac, and C. Westenfelder Hematopoietic stem cell mobilization-associated granulocytosis severely worsens acute renal failure J. Am. Soc. Nephrol. 15 2004 1261 1267 (Pubitemid 38526007)
32. E.J. Sharples, N. Patel, P. Brown, K. Stewart, H. Mota-Philipe, M. Sheaff, J. Kieswich, D. Allen, S. Harwood, M. Raftery, C. Thiemermann, and M.M. Yaqoob Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion J. Am. Soc. Nephrol. 15 2004 2115 2124 (Pubitemid 39031350)
33. C. Sadis, G. Teske, G. Stokman, C. Kubjak, N. Claessen, F. Moore, P. Loi, B. Diallo, L. Barvais, M. Goldman, S. Florquin, and A. Le Moine Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway PLoS One 2 2007 e469
34. K.E. Wever, F.A. Wagener, C. Frielink, O.C. Boerman, G.J. Scheffer, A. Allison, R. Masereeuw, and G.A. Rongen Diannexin protects against renal ischemia reperfusion injury and targets phosphatidylserines in ischemic tissue PLoS One 6 2011 e24276
35. I. Stoilov, A.N. Akarsu, I. Alozie, A. Child, M. Barsoum-Homsy, M.E. Turacli, M. Or, R.A. Lewis, N. Ozdemir, G. Brice, S.G. Aktan, L. Chevrette, M. Coca-Prados, and M. Sarfarazi Sequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome P4501B1 Am. J. Hum. Genet. 62 1998 573 584 (Pubitemid 28164614)
36. K. Hochheiser, A. Tittel, and K. Christian Kidney dendritic cells in acute and chronic renal disease Int. J. Exp. Pathol. 92 2011 193 201
37. D.K. Ysebaert, K.E. De Greef, S.R. Vercauteren, M. Ghielli, G.A. Verpooten, E.J. Eyskens, and M.E. De Broe Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury Nephrol. Dial. Transplant. 15 2000 1562 1574
38. O. Takeuchi, and S. Akira Pattern recognition receptors and inflammation Cell 140 2010 805 820
39. A. Iwasaki, and R. Medzhitov Regulation of adaptive immunity by the innate immune system Science 327 2010 291 295
40. C. Nathan Points of control in inflammation Nature 420 2002 846 852 (Pubitemid 36019637)
41. K.S. Kobayashi, and R.A. Flavell Shielding the double-edged sword: negative regulation of the innate immune system J. Leukoc. Biol. 75 2004 428 433 (Pubitemid 38316373)
42. R. Medzhitov Inflammation 2010: new adventures of an old flame Cell 140 2010 771 776
43. R. Scrivo, M. Vasile, I. Bartosiewicz, and G. Valesini Inflammation as "common soil" of the multifactorial diseases Autoimmun. Rev. 10 2011 369 374
44. Y. Kikuta, J. Mizomoto, H.W. Strobel, and H. Ohkawa Expression and physiological function of CYP4F subfamily in human eosinophils Biochim. Biophys. Acta 1771 2007 1439 1445
45. J.M. Klausner, I.S. Paterson, G. Goldman, L. Kobzik, C. Rodzen, R. Lawrence, C.R. Valeri, D. Shepro, and H.B. Hechtman Postischemic renal injury is mediated by neutrophils and leukotrienes Am. J. Physiol. 256 1989 F794 F802
46. 4 in acute renal ischemic-reperfusion injury Proc. Natl. Acad. Sci. U. S. A. 97 2000 823 828 (Pubitemid 30070394)
47. N.S.A. Patel, S. Cuzzocrea, P.K. Chatterjee, R. Di Paola, L. Sautebin, D. Britti, and C. Thiemermann Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton Mol. Pharmacol. 66 2004 220 227 (Pubitemid 38989478)
48. A.S. Awad, M. Rouse, L. Huang, A.L. Vergis, J. Reutershan, H.P. Cathro, J. Linden, and M.D. Okusa Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury Kidney Int. 75 2009 689 698
49. X. Dong, S. Swaminathan, L.A. Bachman, A.J. Croatt, K.A. Nath, and M.D. Griffin Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury Kidney Int. 71 2007 619 628 (Pubitemid 46494569)
50. K. Furuichi, J.-L. Gao, R. Horuk, T. Wada, S. Kaneko, and P.M. Murphy Chemokine receptor CCR1 regulates inflammatory cell infiltration after renal ischemia-reperfusion injury J. Immunol. 181 2008 8670 8676
51. H.R. Jang, and H. Rabb The innate immune response in ischemic acute kidney injury Clin. Immunol. 130 2009 41 50
52. L. Li, and M.D. Okusa Macrophages, dendritic cells, and kidney ischemia-reperfusion injury Semin. Nephrol. 30 2010 268 277
53. Y. Kikuta, Y. Yamashita, S. Kashiwagi, K. Tani, K. Okada, and K. Nakata Expression and induction of CYP4F subfamily in human leukocytes and HL60 cells Biochim. Biophys. Acta 1683 2004 7 15 (Pubitemid 38844654)