Nucleosome Acidic Patch Promotes RNF168- and RING1B/BMI1-Dependent H2AX and H2A Ubiquitination and DNA Damage Signaling

PLoS Genetics

Volumn 10, Issue 3, 2014, Pages

  Leung, Justin W ^a   Agarwal, Poonam ^a   Canny, Marella D ^b   Gong, Fade ^a   Robison, Aaron D ^a   Finkelstein, Ilya J ^a   Durocher, Daniel ^b   Miller, Kyle M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; HISTONE H2A; HISTONE H2AX; UBIQUITIN PROTEIN LIGASE E3; BMI1 PROTEIN; CELL CYCLE PROTEIN; CHROMATIN; DNA BINDING PROTEIN; H2AFX PROTEIN, HUMAN; HISTONE; NUCLEOSOME; PROTEIN BINDING; RNF168 PROTEIN, HUMAN; RNF2 PROTEIN, HUMAN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CELL FUNCTION; CELL STRUCTURE; CELLULAR PARAMETERS; CHROMATIN; CONTROLLED STUDY; DNA DAMAGE; GENE IDENTIFICATION; HISTONE MODIFICATION; HISTONE UBIQUITINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MUTATIONAL ANALYSIS; NUCLEOSOME; NUCLEOSOME ACIDIC PATCH REGION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; DNA REPAIR; GENETICS; HEK293 CELL LINE; METABOLISM; UBIQUITINATION;

CELL CYCLE PROTEINS; CHROMATIN; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; HEK293 CELLS; HISTONES; HUMANS; NUCLEOSOMES; POLYCOMB REPRESSIVE COMPLEX 1; PROTEIN BINDING; SIGNAL TRANSDUCTION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84897449829     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004178     Document Type: Article

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