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Volumn 10, Issue , 2014, Pages 767-791

Epidemiological, neurobiological, and genetic clues to the mechanisms linking cannabis use to risk for nonaffective psychosis

Author keywords

Cannabidiol; Gene environment interaction; Psychosis; Schizophrenia; THC

Indexed keywords

ACETYLCHOLINE; ANANDAMIDE; CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CATECHOL METHYLTRANSFERASE; ENDOCANNABINOID; G PROTEIN COUPLED RECEPTOR; PSYCHEDELIC AGENT; SEROTONIN; VANILLOID RECEPTOR;

EID: 84897446932     PISSN: 15485943     EISSN: 15485951     Source Type: Book Series    
DOI: 10.1146/annurev-clinpsy-032813-153631     Document Type: Review
Times cited : (41)

References (143)
  • 1
    • 84890242585 scopus 로고    scopus 로고
    • Psychosis-inducing effects of cannabis are related to both childhood abuse and COMT genotypes
    • Alemany S, Arias B, Fatjo-Vilas M, Villa H, Moya J, et al. 2014. Psychosis-inducing effects of cannabis are related to both childhood abuse and COMT genotypes. Acta Psychiatr. Scand. 129:54-62
    • (2014) Acta Psychiatr. Scand , vol.129 , pp. 54-62
    • Alemany, S.1    Arias, B.2    Fatjo-Vilas, M.3    Villa, H.4    Moya, J.5
  • 2
    • 84855272776 scopus 로고    scopus 로고
    • Modulation of L-Alphalysophosphatidylinositol/GPR55 mitogen-Activated protein kinase (MAPK) signaling by cannabinoids
    • Anavi-Goffer S, Baillie G, Irving AJ, Gertsch J, Greig IR, et al. 2012. Modulation of L-Alphalysophosphatidylinositol/GPR55 mitogen-Activated protein kinase (MAPK) signaling by cannabinoids. J. Biol. Chem. 287:91-104
    • (2012) J. Biol. Chem , vol.287 , pp. 91-104
    • Anavi-Goffer, S.1    Baillie, G.2    Irving, A.J.3    Gertsch, J.4    Greig, I.R.5
  • 3
    • 84867028653 scopus 로고    scopus 로고
    • The yin and yang of cannabis-induced psychosis: The actions of -(9)-Tetrahydrocannabinol and cannabidiol in rodent models of schizophrenia
    • Arnold JC, Boucher AA, Karl T. 2012. The yin and yang of cannabis-induced psychosis: The actions of -(9)-Tetrahydrocannabinol and cannabidiol in rodent models of schizophrenia. Curr. Pharm. Des. 18:5113-30
    • (2012) Curr. Pharm. des , vol.18 , pp. 5113-5130
    • Arnold, J.C.1    Boucher, A.A.2    Karl, T.3
  • 4
    • 44449109468 scopus 로고    scopus 로고
    • Corpus callosum damage in heavy marijuana use: Preliminary evidence from diffusion tensor tractography and tract-based spatial statistics
    • Arnone D, Barrick TR, Chengappa S, Mackay CE, Clark CA, Abou-Saleh MT. 2008. Corpus callosum damage in heavy marijuana use: Preliminary evidence from diffusion tensor tractography and tract-based spatial statistics. NeuroImage 41:1067-74
    • (2008) NeuroImage , vol.41 , pp. 1067-1074
    • Arnone, D.1    Barrick, T.R.2    Chengappa, S.3    MacKay, C.E.4    Clark, C.A.5    Abou-Saleh, M.T.6
  • 5
    • 0037164390 scopus 로고    scopus 로고
    • Cannabis use in adolescence and risk for adult psychosis: Longitudinal prospective study
    • Arseneault L, Cannon M, Poulton R, Murray R, Caspi A, Moffitt TE. 2002. Cannabis use in adolescence and risk for adult psychosis: Longitudinal prospective study. BMJ 325:1212-13
    • (2002) BMJ , vol.325 , pp. 1212-1213
    • Arseneault, L.1    Cannon, M.2    Poulton, R.3    Murray, R.4    Caspi, A.5    Moffitt, T.E.6
  • 6
    • 41149091749 scopus 로고    scopus 로고
    • Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala
    • Azad SC, Kurz J, Marsicano G, Lutz B, Zieglgansberger W, Rammes G. 2008. Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala. Learn. Mem. 15:143-52
    • (2008) Learn. Mem , vol.15 , pp. 143-152
    • Azad, S.C.1    Kurz, J.2    Marsicano, G.3    Lutz, B.4    Zieglgansberger, W.5    Rammes, G.6
  • 7
    • 4644350311 scopus 로고    scopus 로고
    • Long-lasting self-inhibition of neocortical interneurons mediated by endocannabinoids
    • Bacci A, Huguenard JR, Prince DA. 2004. Long-lasting self-inhibition of neocortical interneurons mediated by endocannabinoids. Nature 431:312-16
    • (2004) Nature , vol.431 , pp. 312-316
    • Bacci, A.1    Huguenard, J.R.2    Prince, D.A.3
  • 8
    • 82955215765 scopus 로고    scopus 로고
    • Does intravenous-9-Tetrahydrocannabinol increase dopamine release? A SPET study
    • Barkus E, Morrison PD, Vuletic D, Dickson JC, Ell PJ, et al. 2011. Does intravenous-9-Tetrahydrocannabinol increase dopamine release? A SPET study. J. Psychopharmacol. 25:1462-68
    • (2011) J. Psychopharmacol , vol.25 , pp. 1462-1468
    • Barkus, E.1    Morrison, P.D.2    Vuletic, D.3    Dickson, J.C.4    Ell, P.J.5
  • 9
    • 84904246205 scopus 로고    scopus 로고
    • Modulation of brain structure by catechol-o-methyltransferase Val 158)Met polymorphism in chronic cannabis users
    • In press. doi:10.1111/adb.12027
    • Batalla A, Soriano-Mas C, Lopez-Sola M, Torrens M, Crippa JA, et al. 2013. Modulation of brain structure by catechol-o-methyltransferase Val(158)Met polymorphism in chronic cannabis users. Addict. Biol. In press. doi:10.1111/adb.12027
    • (2013) Addict. Biol
    • Batalla, A.1    Soriano-Mas, C.2    Lopez-Sola, M.3    Torrens, M.4    Crippa, J.A.5
  • 11
    • 84861183838 scopus 로고    scopus 로고
    • Chronic adolescent exposure to delta-9-Tetrahydrocannabinol in COMT mutant mice: Impact on indices of dopaminergic, endocannabinoid and GABAergic pathways
    • Behan A, Hryniewiecka M, O'Tuathaigh CM, Kinsella A, Cannon M, et al. 2012. Chronic adolescent exposure to delta-9-Tetrahydrocannabinol in COMT mutant mice: Impact on indices of dopaminergic, endocannabinoid and GABAergic pathways. Neuropsychopharmacology 37:1773-83
    • (2012) Neuropsychopharmacology , vol.37 , pp. 1773-1783
    • Behan, A.1    Hryniewiecka, M.2    O'Tuathaigh, C.M.3    Kinsella, A.4    Cannon, M.5
  • 12
    • 84855316451 scopus 로고    scopus 로고
    • Induction of psychosis by-9-Tetrahydrocannabinol reflects modulation of prefrontal and striatal function during attentional salience processing
    • Bhattacharyya S, Crippa JA, Allen P, Martin-Santos R, Borgwardt S, et al. 2012. Induction of psychosis by-9-Tetrahydrocannabinol reflects modulation of prefrontal and striatal function during attentional salience processing. Arch. Gen. Psychiatry 69:27-36
    • (2012) Arch. Gen. Psychiatry , vol.69 , pp. 27-36
    • Bhattacharyya, S.1    Crippa, J.A.2    Allen, P.3    Martin-Santos, R.4    Borgwardt, S.5
  • 15
    • 55349114694 scopus 로고    scopus 로고
    • Neural basis of -9-Tetrahydrocannabinol and cannabidiol: Effects during response inhibition
    • Borgwardt SJ, Allen P, Bhattacharyya S, Fusar-Poli P, Crippa JA, et al. 2008. Neural basis of -9-Tetrahydrocannabinol and cannabidiol: Effects during response inhibition. Biol. Psychiatry 64:966-73
    • (2008) Biol. Psychiatry , vol.64 , pp. 966-973
    • Borgwardt, S.J.1    Allen, P.2    Bhattacharyya, S.3    Fusar-Poli, P.4    Crippa, J.A.5
  • 16
    • 77955992306 scopus 로고    scopus 로고
    • Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia
    • Bossong MG, Niesink RJ. 2010. Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia. Prog. Neurobiol. 92:370-85
    • (2010) Prog. Neurobiol , vol.92 , pp. 370-385
    • Bossong, M.G.1    Niesink, R.J.2
  • 19
    • 20944446077 scopus 로고    scopus 로고
    • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: Longitudinal evidence of a gene X environment interaction
    • Caspi A, Moffitt TE, Cannon M, McClay J, Murray R, et al. 2005. Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: Longitudinal evidence of a gene X environment interaction. Biol. Psychiatry 57:1117-27
    • (2005) Biol. Psychiatry , vol.57 , pp. 1117-1127
    • Caspi, A.1    Moffitt, T.E.2    Cannon, M.3    McClay, J.4    Murray, R.5
  • 21
    • 78649374688 scopus 로고    scopus 로고
    • TRPV1 activation by endogenous anandamide triggers postsynaptic long-Term depression in dentate gyrus
    • Chavez AE, Chiu CQ, Castillo PE. 2010. TRPV1 activation by endogenous anandamide triggers postsynaptic long-Term depression in dentate gyrus. Nat. Neurosci. 13:1511-18
    • (2010) Nat. Neurosci , vol.13 , pp. 1511-1518
    • Chavez, A.E.1    Chiu, C.Q.2    Castillo, P.E.3
  • 22
    • 6344265879 scopus 로고    scopus 로고
    • Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): Effects on mRNA, protein, and enzyme activity in postmortem human brain
    • Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M, et al. 2004. Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): Effects on mRNA, protein, and enzyme activity in postmortem human brain. Am. J. Hum. Genet. 75:807-21
    • (2004) Am. J. Hum. Genet , vol.75 , pp. 807-821
    • Chen, J.1    Lipska, B.K.2    Halim, N.3    Ma, Q.D.4    Matsumoto, M.5
  • 24
    • 79952312080 scopus 로고    scopus 로고
    • Interaction between COMT haplotypes and cannabis in schizophrenia: A case-only study in two samples from Spain
    • Costas J, Sanjuan J, Ramos-Rios R, Paz E, Agra S, et al. 2011. Interaction between COMT haplotypes and cannabis in schizophrenia: A case-only study in two samples from Spain. Schizophr. Res. 127:22-27
    • (2011) Schizophr. Res , vol.127 , pp. 22-27
    • Costas, J.1    Sanjuan, J.2    Ramos-Rios, R.3    Paz, E.4    Agra, S.5
  • 25
    • 33847641514 scopus 로고    scopus 로고
    • Does normal developmental expression of psychosis combine with environmental risk to cause persistence of psychosis? A psychosis proneness-persistence model
    • Cougnard A, Marcelis M, Myin-Germeys I, De Graaf R, Vollebergh W, et al. 2007. Does normal developmental expression of psychosis combine with environmental risk to cause persistence of psychosis? A psychosis proneness-persistence model. Psychol. Med. 37:513-27
    • (2007) Psychol. Med , vol.37 , pp. 513-527
    • Cougnard, A.1    Marcelis, M.2    Myin-Germeys, I.3    De Graaf, R.4    Vollebergh, W.5
  • 26
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • Cross-Disord. Group Psychiatr. Genomics Consort
    • Cross-Disord. Group Psychiatr. Genomics Consort., Smoller JW, Craddock N, Kendler KS, Lee PH, et al. 2013. Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis. Lancet 381:1371-79
    • (2013) Lancet , vol.381 , pp. 1371-1379
    • Smoller, J.W.1    Craddock, N.2    Kendler, K.S.3    Lee, P.H.4
  • 27
    • 3242789385 scopus 로고    scopus 로고
    • The psychotomimetic effects of intravenous delta-9-Tetrahydrocannabinol in healthy individuals: Implications for psychosis
    • D'Souza DC, Perry E, MacDougall L, Ammerman Y, Cooper T, et al. 2004. The psychotomimetic effects of intravenous delta-9-Tetrahydrocannabinol in healthy individuals: Implications for psychosis. Neuropsychopharmacology 29:1558-72
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1558-1572
    • D'Souza, D.C.1    Perry, E.2    MacDougall, L.3    Ammerman, Y.4    Cooper, T.5
  • 28
    • 84875485080 scopus 로고    scopus 로고
    • Genetic variation underlying psychosis-inducing effects of cannabis: Critical review and future directions
    • Decoster J, Van Os J, Myin-Germeys I, De Hert M, van Winkel R. 2012. Genetic variation underlying psychosis-inducing effects of cannabis: Critical review and future directions. Curr. Pharm. Des. 18:5015-23
    • (2012) Curr. Pharm. des , vol.18 , pp. 5015-5023
    • Decoster, J.1    Van Os, J.2    Myin-Germeys, I.3    De Hert, M.4    Van Winkel, R.5
  • 29
    • 79952696792 scopus 로고    scopus 로고
    • Diminished gray matter in the hippocampus of cannabis users: Possible protective effects of cannabidiol
    • Demirakca T, Sartorius A, Ende G, Meyer N, Welzel H, et al. 2011. Diminished gray matter in the hippocampus of cannabis users: Possible protective effects of cannabidiol. Drug Alcohol Depend. 114:242-45
    • (2011) Drug Alcohol Depend , vol.114 , pp. 242-245
    • Demirakca, T.1    Sartorius, A.2    Ende, G.3    Meyer, N.4    Welzel, H.5
  • 30
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, et al. 1992. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258:1946-49
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hanus, L.2    Breuer, A.3    Pertwee, R.G.4    Stevenson, L.A.5
  • 31
    • 84867743306 scopus 로고    scopus 로고
    • Confirmation that the AKT1 (rs2494732) genotype influences the risk of psychosis in cannabis users
    • Di Forti M, Iyegbe C, Sallis H, Kolliakou A, Falcone A, et al. 2012. Confirmation that the AKT1 (rs2494732) genotype influences the risk of psychosis in cannabis users. Biol. Psychiatry 72:811-16
    • (2012) Biol. Psychiatry , vol.72 , pp. 811-816
    • Di Forti, M.1    Iyegbe, C.2    Sallis, H.3    Kolliakou, A.4    Falcone, A.5
  • 32
    • 78651273649 scopus 로고    scopus 로고
    • Evidence that onset of clinical psychosis is an outcome of progressively more persistent subclinical psychotic experiences: An 8-year cohort study
    • Dominguez MD, Wichers M, Lieb R, Wittchen HU, van Os J. 2011. Evidence that onset of clinical psychosis is an outcome of progressively more persistent subclinical psychotic experiences: An 8-year cohort study. Schizophr. Bull. 37:84-93
    • (2011) Schizophr. Bull , vol.37 , pp. 84-93
    • Dominguez, M.D.1    Wichers, M.2    Lieb, R.3    Wittchen, H.U.4    Van Os, J.5
  • 33
    • 80051953349 scopus 로고    scopus 로고
    • A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry
    • Duncan LE, Keller MC. 2011. A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry. Am. J. Psychiatry 168:1041-49
    • (2011) Am. J. Psychiatry , vol.168 , pp. 1041-1049
    • Duncan, L.E.1    Keller, M.C.2
  • 34
    • 84879507260 scopus 로고    scopus 로고
    • Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: Findings in a second cohort
    • Egerton A, Chaddock CA, Winton-Brown TT, Bloomfield MA, Bhattacharyya S, et al. 2013. Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: Findings in a second cohort. Biol. Psychiatry 74:106-12
    • (2013) Biol. Psychiatry , vol.74 , pp. 106-112
    • Egerton, A.1    Chaddock, C.A.2    Winton-Brown, T.T.3    Bloomfield, M.A.4    Bhattacharyya, S.5
  • 35
    • 0032935782 scopus 로고    scopus 로고
    • Specific attentional dysfunction in adults following early start of cannabis use
    • Ehrenreich H, Rinn T, Kunert HJ, Moeller MR, Poser W, et al. 1999. Specific attentional dysfunction in adults following early start of cannabis use. Psychopharmacology 142:295-301
    • (1999) Psychopharmacology , vol.142 , pp. 295-301
    • Ehrenreich, H.1    Rinn, T.2    Kunert, H.J.3    Moeller, M.R.4    Poser, W.5
  • 37
    • 84871534813 scopus 로고    scopus 로고
    • Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment
    • Englund A, Morrison PD, Nottage J, Hague D, Kane F, et al. 2013. Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment. J. Psychopharmacol. 27:19-27
    • (2013) J. Psychopharmacol , vol.27 , pp. 19-27
    • Englund, A.1    Morrison, P.D.2    Nottage, J.3    Hague, D.4    Kane, F.5
  • 38
    • 79955980417 scopus 로고    scopus 로고
    • Cannabis use and age at onset of psychosis: Further evidence of interaction with COMT Val158Met polymorphism
    • Estrada G, Fatj́o-Vilas M, Muñoz MJ, Pulido G, Miñano MJ, et al. 2011. Cannabis use and age at onset of psychosis: Further evidence of interaction with COMT Val158Met polymorphism. Acta Psychiatr. Scand. 123:485-92
    • (2011) Acta Psychiatr. Scand , vol.123 , pp. 485-492
    • Estrada, G.1    Fatj́o-Vilas, M.2    Muñoz, M.J.3    Pulido, G.4    Miñano, M.J.5
  • 41
    • 77953542908 scopus 로고    scopus 로고
    • Modulation of effective connectivity during emotional processing by -9-Tetrahydrocannabinol and cannabidiol
    • Fusar-Poli P, Allen P, Bhattacharyya S, Crippa JA, Mechelli A, et al. 2010. Modulation of effective connectivity during emotional processing by -9-Tetrahydrocannabinol and cannabidiol. Int. J. Neuropsychopharmacol. 13:421-32
    • (2010) Int. J. Neuropsychopharmacol , vol.13 , pp. 421-432
    • Fusar-Poli, P.1    Allen, P.2    Bhattacharyya, S.3    Crippa, J.A.4    Mechelli, A.5
  • 42
    • 58149520644 scopus 로고    scopus 로고
    • Distinct effects of -9-Tetrahydrocannabinol and cannabidiol on neural activation during emotional processing
    • Fusar-Poli P, Crippa JA, Bhattacharyya S, Borgwardt SJ, Allen P, et al. 2009. Distinct effects of -9-Tetrahydrocannabinol and cannabidiol on neural activation during emotional processing. Arch. Gen. Psychiatry 66:95-105
    • (2009) Arch. Gen. Psychiatry , vol.66 , pp. 95-105
    • Fusar-Poli, P.1    Crippa, J.A.2    Bhattacharyya, S.3    Borgwardt, S.J.4    Allen, P.5
  • 43
    • 79951497637 scopus 로고    scopus 로고
    • Evidence that familial liability for psychosis is expressed as differential sensitivity to cannabis: An analysis of patient-sibling and sibling-control pairs
    • Genetic Risk Outcome Psychos. (GROUP Investig
    • Genetic Risk Outcome Psychos. (GROUP) Investig. 2011. Evidence that familial liability for psychosis is expressed as differential sensitivity to cannabis: An analysis of patient-sibling and sibling-control pairs. Arch. Gen. Psychiatry 68:138-47
    • (2011) Arch. Gen. Psychiatry , vol.68 , pp. 138-147
  • 44
    • 78649369301 scopus 로고    scopus 로고
    • Postsynaptic TRPV1 triggers cell type-specific long-Term depression in the nucleus accumbens
    • Grueter BA, Brasnjo G, Malenka RC. 2010. Postsynaptic TRPV1 triggers cell type-specific long-Term depression in the nucleus accumbens. Nat. Neurosci. 13:1519-25
    • (2010) Nat. Neurosci , vol.13 , pp. 1519-1525
    • Grueter, B.A.1    Brasnjo, G.2    Malenka, R.C.3
  • 45
    • 70349453743 scopus 로고    scopus 로고
    • Variability in the COMT gene and modification of the risk of schizophrenia conferred by cannabis consumption
    • Gutíerrez B, Rivera M, Obel L, McKenney K, Mart́inez-Leal R, et al. 2009. Variability in the COMT gene and modification of the risk of schizophrenia conferred by cannabis consumption. Rev. Psiquiatr. Salud Ment. 2:89-94
    • (2009) Rev. Psiquiatr. Salud Ment , vol.2 , pp. 89-94
    • Gutíerrez, B.1    Rivera, M.2    Obel, L.3    McKenney, K.4    Mart́inez-Leal, R.5
  • 46
    • 78149461645 scopus 로고    scopus 로고
    • Reduced cortical thickness as an outcome of differential sensitivity to environmental risks in schizophrenia
    • Habets P, Marcelis M, Gronenschild E, Drukker M, van Os J. 2011. Reduced cortical thickness as an outcome of differential sensitivity to environmental risks in schizophrenia. Biol. Psychiatry 69:487-94
    • (2011) Biol. Psychiatry , vol.69 , pp. 487-494
    • Habets, P.1    Marcelis, M.2    Gronenschild, E.3    Drukker, M.4    Van Os, J.5
  • 47
    • 0032517566 scopus 로고    scopus 로고
    • Adverse effects of cannabis
    • Hall W, Solowij N. 1998. Adverse effects of cannabis. Lancet 352:1611-16
    • (1998) Lancet , vol.352 , pp. 1611-1616
    • Hall, W.1    Solowij, N.2
  • 48
    • 77957113186 scopus 로고    scopus 로고
    • Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence
    • Harley M, Kelleher I, Clarke M, Lynch F, Arseneault L, et al. 2010. Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence. Psychol. Med. 40:1627-34
    • (2010) Psychol. Med , vol.40 , pp. 1627-1634
    • Harley, M.1    Kelleher, I.2    Clarke, M.3    Lynch, F.4    Arseneault, L.5
  • 49
    • 11244260452 scopus 로고    scopus 로고
    • Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people
    • Henquet C, Krabbendam L, Spauwen J, Kaplan C, Lieb R, et al. 2005a. Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people. BMJ 330:11-14
    • (2005) BMJ , vol.330 , pp. 11-14
    • Henquet, C.1    Krabbendam, L.2    Spauwen, J.3    Kaplan, C.4    Lieb, R.5
  • 50
    • 24344470642 scopus 로고    scopus 로고
    • The environment and schizophrenia: The role of cannabis use
    • Henquet C, Murray R, Linszen D, van Os J. 2005b. The environment and schizophrenia: The role of cannabis use. Schizophr. Bull. 31:608-12
    • (2005) Schizophr. Bull , vol.31 , pp. 608-612
    • Henquet, C.1    Murray, R.2    Linszen, D.3    Van Os, J.4
  • 51
    • 58449110608 scopus 로고    scopus 로고
    • COMT ValMet moderation of cannabisinduced psychosis: A momentary assessment study of "switching on" hallucinations in the flow of daily life
    • Henquet C, Rosa A, Delespaul P, Papiol S, Fananas L, et al. 2009. COMT ValMet moderation of cannabisinduced psychosis: A momentary assessment study of "switching on" hallucinations in the flow of daily life. Acta Psychiatr. Scand. 119:156-60
    • (2009) Acta Psychiatr. Scand , vol.119 , pp. 156-160
    • Henquet, C.1    Rosa, A.2    Delespaul, P.3    Papiol, S.4    Fananas, L.5
  • 52
    • 33751119258 scopus 로고    scopus 로고
    • An experimental study of catechol-omethyltransferase Val158Met moderation of delta-9-Tetrahydrocannabinol-induced effects on psychosis and cognition
    • Henquet C, Rosa A, Krabbendam L, Papiol S, Fananas L, et al. 2006. An experimental study of catechol-omethyltransferase Val158Met moderation of delta-9-Tetrahydrocannabinol-induced effects on psychosis and cognition. Neuropsychopharmacology 31:2748-57
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2748-2757
    • Henquet, C.1    Rosa, A.2    Krabbendam, L.3    Papiol, S.4    Fananas, L.5
  • 53
    • 33846833572 scopus 로고    scopus 로고
    • Opposing actions of chronic -9-Tetrahydrocannabinol and cannabinoid antagonists on hippocampal long-Term potentiation
    • Hoffman AF, Oz M, Yang R, Lichtman AH, Lupica CR. 2007. Opposing actions of chronic -9-Tetrahydrocannabinol and cannabinoid antagonists on hippocampal long-Term potentiation. Learn. Mem. 14:63-74
    • (2007) Learn. Mem , vol.14 , pp. 63-74
    • Hoffman, A.F.1    Oz, M.2    Yang, R.3    Lichtman, A.H.4    Lupica, C.R.5
  • 54
    • 53149098183 scopus 로고    scopus 로고
    • Different psychological effects of cannabis use in adolescents at genetic high risk for schizophrenia and with attention deficit/hyperactivity disorder (ADHD
    • Hollis C, Groom MJ, Das D, Calton T, Bates AT, et al. 2008. Different psychological effects of cannabis use in adolescents at genetic high risk for schizophrenia and with attention deficit/hyperactivity disorder (ADHD). Schizophr. Res. 105:216-23
    • (2008) Schizophr. Res , vol.105 , pp. 216-223
    • Hollis, C.1    Groom, M.J.2    Das, D.3    Calton, T.4    Bates, A.T.5
  • 55
    • 48749125099 scopus 로고    scopus 로고
    • Childhood sexual abuse, early cannabis use, and psychosis: Testing an interaction model based on the National Comorbidity Survey
    • Houston JE, Murphy J, Adamson G, Stringer M, Shevlin M. 2008. Childhood sexual abuse, early cannabis use, and psychosis: Testing an interaction model based on the National Comorbidity Survey. Schizophr. Bull. 34:580-85
    • (2008) Schizophr. Bull , vol.34 , pp. 580-585
    • Houston, J.E.1    Murphy, J.2    Adamson, G.3    Stringer, M.4    Shevlin, M.5
  • 56
    • 80054916850 scopus 로고    scopus 로고
    • Cannabis use and psychosis: Re-visiting the role of childhood trauma
    • Houston JE, Murphy J, Shevlin M, Adamson G. 2011. Cannabis use and psychosis: Re-visiting the role of childhood trauma. Psychol. Med. 41:2339-48
    • (2011) Psychol. Med , vol.41 , pp. 2339-2348
    • Houston, J.E.1    Murphy, J.2    Shevlin, M.3    Adamson, G.4
  • 57
    • 84865309293 scopus 로고    scopus 로고
    • The nature of dopamine dysfunction in schizophrenia and what this means for treatment
    • Howes OD, Kambeitz J, Kim E, Stahl D, Slifstein M, et al. 2012. The nature of dopamine dysfunction in schizophrenia and what this means for treatment. Arch. Gen. Psychiatry 69:776-86
    • (2012) Arch. Gen. Psychiatry , vol.69 , pp. 776-786
    • Howes, O.D.1    Kambeitz, J.2    Kim, E.3    Stahl, D.4    Slifstein, M.5
  • 59
    • 71449103952 scopus 로고    scopus 로고
    • Adolescent cannabis use, psychosis and catechol-O-methyltransferase genotype in African Americans and Caucasians
    • Kantrowitz JT, Nolan KA, Sen S, Simen A, Lachman HM, Bowers M. 2009. Adolescent cannabis use, psychosis and catechol-O-methyltransferase genotype in African Americans and Caucasians. Psychiatr.Q. 80:213-18
    • (2009) Psychiatr.Q. , vol.80 , pp. 213-218
    • Kantrowitz, J.T.1    Nolan, K.A.2    Sen, S.3    Simen, A.4    Lachman, H.M.5    Bowers, M.6
  • 60
    • 79960358613 scopus 로고    scopus 로고
    • Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels
    • Klugmann M, Klippenstein V, Leweke FM, Spanage lR, Schneider M. 2011. Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels. Int. J. Neuropsychopharmacol. 14:505-17
    • (2011) Int. J. Neuropsychopharmacol , vol.14 , pp. 505-517
    • Klugmann, M.1    Klippenstein, V.2    Leweke, F.M.3    Spanage, L.R.4    Schneider, M.5
  • 61
    • 33745088737 scopus 로고    scopus 로고
    • Validity and reliability of the CAPE: A selfreport instrument for the measurement of psychotic experiences in the general population
    • Konings M, Bak M, Hanssen M, van Os J, Krabbendam L. 2006. Validity and reliability of the CAPE: A selfreport instrument for the measurement of psychotic experiences in the general population. Acta Psychiatr. Scand. 114:55-61
    • (2006) Acta Psychiatr. Scand , vol.114 , pp. 55-61
    • Konings, M.1    Bak, M.2    Hanssen, M.3    Van Os, J.4    Krabbendam, L.5
  • 63
    • 82555205403 scopus 로고    scopus 로고
    • Replication in two independent population-based samples that childhood maltreatment and cannabis use synergistically impact on psychosis risk
    • Konings M, Stefanis N, Kuepper R, de Graaf R, ten Have M, et al. 2012. Replication in two independent population-based samples that childhood maltreatment and cannabis use synergistically impact on psychosis risk. Psychol. Med. 42:149-59
    • (2012) Psychol. Med , vol.42 , pp. 149-159
    • Konings, M.1    Stefanis, N.2    Kuepper, R.3    De Graaf, R.4    Ten Have, M.5
  • 64
    • 84880810573 scopus 로고    scopus 로고
    • Delta-9-Tetrahydrocannabinol-induced dopamine release as a function of psychosis risk:18F-fallypride positron emission tomography study
    • Kuepper R, Ceccarini J, Lataster J, Van Os J, Van Kroonenburgh M, et al. 2013. Delta-9-Tetrahydrocannabinol-induced dopamine release as a function of psychosis risk:18F-fallypride positron emission tomography study. PLoS ONE 8:e70378
    • (2013) PLoS ONE , vol.8
    • Kuepper, R.1    Ceccarini, J.2    Lataster, J.3    Van Os, J.4    Van Kroonenburgh, M.5
  • 65
    • 80051788784 scopus 로고    scopus 로고
    • Non-replication of interaction between cannabis use and trauma in predicting psychosis
    • Kuepper R, Henquet C, Lieb R, Wittchen HU, van Os J. 2011a. Non-replication of interaction between cannabis use and trauma in predicting psychosis. Schizophr. Res. 131:262-63
    • (2011) Schizophr. Res , vol.131 , pp. 262-263
    • Kuepper, R.1    Henquet, C.2    Lieb, R.3    Wittchen, H.U.4    Van Os, J.5
  • 66
    • 77955054913 scopus 로고    scopus 로고
    • Does dopamine mediate the psychosis-inducing effects of cannabis? A review and integration of findings across disciplines
    • Kuepper R, Morrison PD, van Os J, Murray RM, Kenis G, Henquet C. 2010. Does dopamine mediate the psychosis-inducing effects of cannabis? A review and integration of findings across disciplines. Schizophr. Res. 121:107-17
    • (2010) Schizophr. Res , vol.121 , pp. 107-117
    • Kuepper, R.1    Morrison, P.D.2    Van Os, J.3    Murray, R.M.4    Kenis, G.5    Henquet, C.6
  • 67
    • 80054921485 scopus 로고    scopus 로고
    • Do cannabis and urbanicity co-participate in causing psychosis? Evidence from a 10-year follow-up cohort study
    • Kuepper R, van Os J, Lieb R, Wittchen HU, Henquet C. 2011b. Do cannabis and urbanicity co-participate in causing psychosis? Evidence from a 10-year follow-up cohort study. Psychol. Med. 41:2121-9
    • (2011) Psychol. Med , vol.41 , pp. 2121-2129
    • Kuepper, R.1    Van Os, J.2    Lieb, R.3    Wittchen, H.U.4    Henquet, C.5
  • 68
    • 79952276116 scopus 로고    scopus 로고
    • Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study
    • Kuepper R, van Os J, Lieb R, Wittchen HU, Hofler M, Henquet C. 2011c. Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study. BMJ 342:d738
    • (2011) BMJ , vol.342
    • Kuepper, R.1    Van Os, J.2    Lieb, R.3    Wittchen, H.U.4    Hofler, M.5    Henquet, C.6
  • 69
    • 0016931745 scopus 로고
    • Proceedings: Alterations in dopamine uptake in rat corpus striatum induced by combinations of stress and delta8-Tetrahydrocannabinol (delta8-THC
    • Littleton JM, MacLean KI, Brownlee G. 1976. Proceedings: Alterations in dopamine uptake in rat corpus striatum induced by combinations of stress and delta8-Tetrahydrocannabinol (delta8-THC). Br. J. Pharmacol. 56:370P
    • (1976) Br. J. Pharmacol , vol.56
    • Littleton, J.M.1    MacLean, K.I.2    Brownlee, G.3
  • 70
    • 43749125007 scopus 로고    scopus 로고
    • The pharmacology of the endocannabinoid system: Functional and structural interactions with other neurotransmitter systems and their repercussions in behavioral addiction
    • Lopez-Moreno JA, Gonzalez-Cuevas G, Moreno G, Navarro M. 2008. The pharmacology of the endocannabinoid system: Functional and structural interactions with other neurotransmitter systems and their repercussions in behavioral addiction. Addict. Biol. 13:160-87
    • (2008) Addict. Biol , vol.13 , pp. 160-187
    • Lopez-Moreno, J.A.1    Gonzalez-Cuevas, G.2    Moreno, G.3    Navarro, M.4
  • 71
    • 20444428308 scopus 로고    scopus 로고
    • Cognitive consequences of cannabis use: Comparison with abuse of stimulants and heroin with regard to attention, memory and executive functions
    • Lundqvist T. 2005. Cognitive consequences of cannabis use: Comparison with abuse of stimulants and heroin with regard to attention, memory and executive functions. Pharmacol. Biochem. Behav. 81:319-30
    • (2005) Pharmacol. Biochem. Behav , vol.81 , pp. 319-330
    • Lundqvist, T.1
  • 72
    • 33645774927 scopus 로고    scopus 로고
    • Distribution of cannabinoid receptors in the central and peripheral nervous system
    • Mackie K. 2005. Distribution of cannabinoid receptors in the central and peripheral nervous system. Handb. Exp. Pharmacol. 168:299-325
    • (2005) Handb. Exp. Pharmacol , vol.168 , pp. 299-325
    • MacKie, K.1
  • 73
    • 0017341071 scopus 로고
    • Environmental stress as a factor in the response of rat brain catecholamine metabolism to delta8-Tetrahydrocannabinol
    • MacLean KI, Littleton JM. 1977. Environmental stress as a factor in the response of rat brain catecholamine metabolism to delta8-Tetrahydrocannabinol. Eur. J. Pharmacol. 41:171-82
    • (1977) Eur. J. Pharmacol , vol.41 , pp. 171-182
    • MacLean, K.I.1    Littleton, J.M.2
  • 76
    • 2542437772 scopus 로고    scopus 로고
    • A single in-vivo exposure to delta 9 THC blocks endocannabinoid-mediated synaptic plasticity
    • Mato S, Chevaleyre V, Robbe D, Pazos A, Castillo PE, Manzoni OJ. 2004. A single in-vivo exposure to delta 9 THC blocks endocannabinoid-mediated synaptic plasticity. Nat. Neurosci. 7:585-86
    • (2004) Nat. Neurosci , vol.7 , pp. 585-586
    • Mato, S.1    Chevaleyre, V.2    Robbe, D.3    Pazos, A.4    Castillo, P.E.5    Manzoni, O.J.6
  • 77
    • 77951853072 scopus 로고    scopus 로고
    • Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults
    • McGrath J, Welham J, Scott J, Varghese D, Degenhardt L, et al. 2010. Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults. Arch. Gen. Psychiatry 67:440-47
    • (2010) Arch. Gen. Psychiatry , vol.67 , pp. 440-447
    • McGrath, J.1    Welham, J.2    Scott, J.3    Varghese, D.4    Degenhardt, L.5
  • 78
    • 0029012014 scopus 로고
    • Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
    • Mechoulam R, Ben-Shabat S, Hanus L, Ligumsky M, Kaminski NE, et al. 1995. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem. Pharmacol. 50:83-90
    • (1995) Biochem. Pharmacol , vol.50 , pp. 83-90
    • Mechoulam, R.1    Ben-Shabat, S.2    Hanus, L.3    Ligumsky, M.4    Kaminski, N.E.5
  • 81
    • 84873739013 scopus 로고    scopus 로고
    • Dopamine response to psychosocial stress in chronic cannabis users: A PET study with [(11 C]-(+)-PHNO
    • Mizrahi R, Suridjan I, Kenk M, George TP, Wilson A, et al. 2013. Dopamine response to psychosocial stress in chronic cannabis users: A PET study with [(11)C]-(+)-PHNO. Neuropsychopharmacology 38:673-82
    • (2013) Neuropsychopharmacology , vol.38 , pp. 673-682
    • Mizrahi, R.1    Suridjan, I.2    Kenk, M.3    George, T.P.4    Wilson, A.5
  • 82
    • 0023370167 scopus 로고
    • Neonatal administration of delta-9-Tetrahydrocannabinol (THC) alters the neurochemical response to stress in the adult Fischer-344 rat
    • Mokler DJ, Robinson SE, Johnson JH, Hong JS, Rosecrans JA. 1987. Neonatal administration of delta-9-Tetrahydrocannabinol (THC) alters the neurochemical response to stress in the adult Fischer-344 rat. Neurotoxicol. Teratol. 9:321-27
    • (1987) Neurotoxicol. Teratol , vol.9 , pp. 321-327
    • Mokler, D.J.1    Robinson, S.E.2    Johnson, J.H.3    Hong, J.S.4    Rosecrans, J.A.5
  • 83
    • 34447619511 scopus 로고    scopus 로고
    • Cannabis use and risk of psychotic or affective mental health outcomes: A systematic review
    • Moore TH, Zammit S, Lingford-Hughes A, Barnes TR, Jones PB, et al. 2007. Cannabis use and risk of psychotic or affective mental health outcomes: A systematic review. Lancet 370:319-28
    • (2007) Lancet , vol.370 , pp. 319-328
    • Moore, T.H.1    Zammit, S.2    Lingford-Hughes, A.3    Barnes, T.R.4    Jones, P.B.5
  • 84
    • 43749124214 scopus 로고    scopus 로고
    • Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis
    • Morgan CJ, Curran HV. 2008. Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis. Br. J. Psychiatry 192:306-7
    • (2008) Br. J. Psychiatry , vol.192 , pp. 306-307
    • Morgan, C.J.1    Curran, H.V.2
  • 85
    • 84857347125 scopus 로고    scopus 로고
    • Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being
    • Morgan CJ, Gardener C, Schafer G, Swan S, Demarchi C, et al. 2012. Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. Psychol. Med. 42:391-400
    • (2012) Psychol. Med , vol.42 , pp. 391-400
    • Morgan, C.J.1    Gardener, C.2    Schafer, G.3    Swan, S.4    Demarchi, C.5
  • 86
    • 77957687873 scopus 로고    scopus 로고
    • Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: Naturalistic study [corrected]
    • Morgan CJ, Schafer G, Freeman TP, Curran HV. 2010. Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: Naturalistic study [corrected]. Br. J. Psychiatry 197:285-90
    • (2010) Br. J. Psychiatry , vol.197 , pp. 285-290
    • Morgan, C.J.1    Schafer, G.2    Freeman, T.P.3    Curran, H.V.4
  • 87
    • 68149158212 scopus 로고    scopus 로고
    • From real-world events to psychosis: The emerging neuropharmacology of delusions
    • Morrison PD, Murray RM. 2009. From real-world events to psychosis: The emerging neuropharmacology of delusions. Schizophr. Bull. 35:668-74
    • (2009) Schizophr. Bull , vol.35 , pp. 668-674
    • Morrison, P.D.1    Murray, R.M.2
  • 88
    • 79953242999 scopus 로고    scopus 로고
    • Synthetic delta-9-Tetrahydrocannabinol elicits schizophrenia-like negative symptoms which are distinct from sedation
    • Morrison PD, Stone JM. 2011. Synthetic delta-9-Tetrahydrocannabinol elicits schizophrenia-like negative symptoms which are distinct from sedation. Hum. Psychopharmacol. 26:77-80
    • (2011) Hum. Psychopharmacol , vol.26 , pp. 77-80
    • Morrison, P.D.1    Stone, J.M.2
  • 89
    • 70449629796 scopus 로고    scopus 로고
    • The acute effects of synthetic intravenous Delta9-Tetrahydrocannabinol on psychosis, mood and cognitive functioning
    • Morrison PD, Zois V, McKeown DA, Lee TD, Holt DW, et al. 2009. The acute effects of synthetic intravenous Delta9-Tetrahydrocannabinol on psychosis, mood and cognitive functioning. Psychol. Med. 39:1607-16
    • (2009) Psychol. Med , vol.39 , pp. 1607-1616
    • Morrison, P.D.1    Zois, V.2    McKeown, D.A.3    Lee, T.D.4    Holt, D.W.5
  • 90
    • 84878574134 scopus 로고    scopus 로고
    • Childhood sexual trauma, cannabis use and psychosis: Statistically controlling for pre-Trauma psychosis and psychopathology
    • Murphy J, Houston JE, Shevlin M, Adamson G. 2013. Childhood sexual trauma, cannabis use and psychosis: Statistically controlling for pre-Trauma psychosis and psychopathology. Soc. Psychiatry Psychiatr. Epidemiol. 48:853-61
    • (2013) Soc. Psychiatry Psychiatr. Epidemiol , vol.48 , pp. 853-861
    • Murphy, J.1    Houston, J.E.2    Shevlin, M.3    Adamson, G.4
  • 93
    • 84870593059 scopus 로고    scopus 로고
    • Genetic vs pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes
    • O'Tuathaigh CM, Clarke G, Walsh JJ, Desbonnet L, Petit E, et al. 2012. Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes. Int. J. Neuropsychopharmacol. 15:1331-42
    • (2012) Int. J. Neuropsychopharmacol , vol.15 , pp. 1331-1342
    • O'Tuathaigh, C.M.1    Clarke, G.2    Walsh, J.J.3    Desbonnet, L.4    Petit, E.5
  • 94
    • 78651274327 scopus 로고    scopus 로고
    • Chronic adolescent exposure to delta-9-Tetrahydrocannabinol in COMT mutant mice: Impact on psychosis-related and other phenotypes
    • O'Tuathaigh CM, Hryniewiecka M, Behan A, Tighe O, Coughlan C, et al. 2010. Chronic adolescent exposure to delta-9-Tetrahydrocannabinol in COMT mutant mice: Impact on psychosis-related and other phenotypes. Neuropsychopharmacology 35:2262-73
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2262-2273
    • O'Tuathaigh, C.M.1    Hryniewiecka, M.2    Behan, A.3    Tighe, O.4    Coughlan, C.5
  • 95
    • 77957221593 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase (COMT) Val158Met variations and cannabis use in first-episode non-Affective psychosis: Clinical-onset implications
    • Pelayo-Teran JM, Perez-Iglesias R, Mata I, Carrasco-Marin E, Vazquez-Barquero JL, Crespo-Facorro B. 2010. Catechol-O-methyltransferase (COMT) Val158Met variations and cannabis use in first-episode non-Affective psychosis: Clinical-onset implications. Psychiatr. Res. 179:291-96
    • (2010) Psychiatr. Res , vol.179 , pp. 291-296
    • Pelayo-Teran, J.M.1    Perez-Iglesias, R.2    Mata, I.3    Carrasco-Marin, E.4    Vazquez-Barquero, J.L.5    Crespo-Facorro, B.6
  • 96
    • 0030611978 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid CB1 and CB2 receptors
    • Pertwee RG. 1997. Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacol. Ther. 74:129-80
    • (1997) Pharmacol. Ther , vol.74 , pp. 129-180
    • Pertwee, R.G.1
  • 97
    • 38349158960 scopus 로고    scopus 로고
    • The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Delta9-Tetrahydrocannabinol, cannabidiol and delta9- Tetrahydrocannabivarin
    • Pertwee RG. 2008. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Delta9-Tetrahydrocannabinol, cannabidiol and delta9-Tetrahydrocannabivarin. Br. J. Pharmacol. 153:199-215
    • (2008) Br. J. Pharmacol , vol.153 , pp. 199-215
    • Pertwee, R.G.1
  • 98
    • 77950653576 scopus 로고    scopus 로고
    • Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists
    • Pertwee RG. 2010. Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists. Curr. Med. Chem. 17:1360-81
    • (2010) Curr. Med. Chem , vol.17 , pp. 1360-1381
    • Pertwee, R.G.1
  • 99
    • 3042752521 scopus 로고    scopus 로고
    • Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons
    • Pistis M, Perra S, Pillolla G, Melis M, Muntoni AL, Gessa GL. 2004. Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons. Biol. Psychiatry 56:86-94
    • (2004) Biol. Psychiatry , vol.56 , pp. 86-94
    • Pistis, M.1    Perra, S.2    Pillolla, G.3    Melis, M.4    Muntoni, A.L.5    Gessa, G.L.6
  • 101
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, et al. 2009. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460:748-52
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5
  • 102
    • 79955463764 scopus 로고    scopus 로고
    • The effects of cannabis use on neurocognition in schizophrenia: A meta-Analysis
    • Rabin RA, Zakzanis KK, George TP. 2011. The effects of cannabis use on neurocognition in schizophrenia: A meta-Analysis. Schizophr. Res. 128:111-16
    • (2011) Schizophr. Res , vol.128 , pp. 111-116
    • Rabin, R.A.1    Zakzanis, K.K.2    George, T.P.3
  • 103
    • 33749314873 scopus 로고    scopus 로고
    • The acute effects of cannabinoids on memory in humans: A review
    • Ranganathan M, D'Souza DC. 2006. The acute effects of cannabinoids on memory in humans: A review. Psychopharmacology 188:425-44
    • (2006) Psychopharmacology , vol.188 , pp. 425-444
    • Ranganathan, M.1    D'Souza, D.C.2
  • 104
    • 67449119178 scopus 로고    scopus 로고
    • Neurobiological alterations at adult age triggered by adolescent exposure to cannabinoids
    • Realini N, Rubino T, Parolaro D. 2009. Neurobiological alterations at adult age triggered by adolescent exposure to cannabinoids. Pharmacol. Res. 60:132-38
    • (2009) Pharmacol. Res , vol.60 , pp. 132-138
    • Realini, N.1    Rubino, T.2    Parolaro, D.3
  • 105
    • 67449147859 scopus 로고    scopus 로고
    • Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood
    • Rubino T, Realini N, Braida D, Guidi S, Capurro V, et al. 2009. Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood. Hippocampus 19:763-72
    • (2009) Hippocampus , vol.19 , pp. 763-772
    • Rubino, T.1    Realini, N.2    Braida, D.3    Guidi, S.4    Capurro, V.5
  • 107
    • 26044438805 scopus 로고    scopus 로고
    • Behavioral effects in adult rats of chronic prepubertal treatment with the cannabinoid receptor agonistWIN 55 212-2
    • Schneider M, Drews E, Koch M. 2005. Behavioral effects in adult rats of chronic prepubertal treatment with the cannabinoid receptor agonistWIN 55,212-2. Behav. Pharmacol. 16:447-54
    • (2005) Behav. Pharmacol , vol.16 , pp. 447-454
    • Schneider, M.1    Drews, E.2    Koch, M.3
  • 108
    • 0642338928 scopus 로고    scopus 로고
    • Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult rats
    • Schneider M, Koch M. 2003. Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult rats. Neuropsychopharmacology 28:1760-69
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1760-1769
    • Schneider, M.1    Koch, M.2
  • 109
    • 33751196600 scopus 로고    scopus 로고
    • The effect of chronic peripubertal cannabinoid treatment on deficient object recognition memory in rats after neonatal mPFC lesion
    • Schneider M, Koch M. 2007. The effect of chronic peripubertal cannabinoid treatment on deficient object recognition memory in rats after neonatal mPFC lesion. Eur. Neuropsychopharmacol. 17:180-86
    • (2007) Eur. Neuropsychopharmacol , vol.17 , pp. 180-186
    • Schneider, M.1    Koch, M.2
  • 110
    • 49349108613 scopus 로고    scopus 로고
    • Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats
    • Schneider M, Schomig E, Leweke FM. 2008. Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats. Addict. Biol. 13:345-57
    • (2008) Addict. Biol , vol.13 , pp. 345-357
    • Schneider, M.1    Schomig, E.2    Leweke, F.M.3
  • 113
    • 56049117857 scopus 로고    scopus 로고
    • Elevated rates of substance use disorders in non-psychotic siblings of individuals with schizophrenia
    • Smith MJ, Barch DM, Wolf T, Mamah D, Csernansky JG. 2008. Elevated rates of substance use disorders in non-psychotic siblings of individuals with schizophrenia. Schizophr. Res. 106:294-99
    • (2008) Schizophr. Res , vol.106 , pp. 294-299
    • Smith, M.J.1    Barch, D.M.2    Wolf, T.3    Mamah, D.4    Csernansky, J.G.5
  • 114
    • 0029017888 scopus 로고
    • Do cognitive impairments recover following cessation of cannabis use?
    • Solowij N 1995. Do cognitive impairments recover following cessation of cannabis use? Life Sci. 56:2119-26
    • (1995) Life Sci , vol.56 , pp. 2119-2126
    • Solowij, N.1
  • 115
    • 57449100592 scopus 로고    scopus 로고
    • The chronic effects of cannabis on memory in humans: A review
    • Solowij N, Battisti R. 2008. The chronic effects of cannabis on memory in humans: A review. Curr. Drug Abuse Rev. 1:81-98
    • (2008) Curr. Drug Abuse Rev , vol.1 , pp. 81-98
    • Solowij, N.1    Battisti, R.2
  • 116
    • 0037029103 scopus 로고    scopus 로고
    • Cognitive functioning of long-Term heavy cannabis users seeking treatment
    • Solowij N, Stephens RS, Roffman RA, Babor T, Kadden R, et al. 2002. Cognitive functioning of long-Term heavy cannabis users seeking treatment. JAMA 287:1123-31
    • (2002) JAMA , vol.287 , pp. 1123-1131
    • Solowij, N.1    Stephens, R.S.2    Roffman, R.A.3    Babor, T.4    Kadden, R.5
  • 117
    • 84871933160 scopus 로고    scopus 로고
    • Alteration to hippocampal shape in cannabis users with and without schizophrenia
    • Solowij N, Walterfang M, Lubman DI, Whittle S, Lorenzetti V, et al. 2013. Alteration to hippocampal shape in cannabis users with and without schizophrenia. Schizophr. Res. 143:179-84
    • (2013) Schizophr. Res , vol.143 , pp. 179-184
    • Solowij, N.1    Walterfang, M.2    Lubman, D.I.3    Whittle, S.4    Lorenzetti, V.5
  • 118
    • 80054916654 scopus 로고    scopus 로고
    • Cerebellar white-matter changes in cannabis users with and without schizophrenia
    • Solowij N, Yücel M, Respondek C, Whittle S, Lindsay E, et al. 2011. Cerebellar white-matter changes in cannabis users with and without schizophrenia. Psychol. Med. 41:2349-59
    • (2011) Psychol. Med , vol.41 , pp. 2349-2359
    • Solowij, N.1    Yücel, M.2    Respondek, C.3    Whittle, S.4    Lindsay, E.5
  • 120
    • 77954958645 scopus 로고    scopus 로고
    • Significant decreases in frontal and temporal [11c]-raclopride binding after thc challenge
    • Stokes PR, Egerton A, Watson B, Reid A, Breen G, et al. 2010. Significant decreases in frontal and temporal [11C]-raclopride binding after THC challenge. NeuroImage 52:1521-27
    • (2010) NeuroImage , vol.52 , pp. 1521-1527
    • Stokes, P.R.1    Egerton, A.2    Watson, B.3    Reid, A.4    Breen, G.5
  • 121
    • 84856437355 scopus 로고    scopus 로고
    • History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability
    • Stokes PR, Egerton A, Watson B, Reid A, Lappin J, et al. 2012. History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability. J. Psychopharmacol. 26:144-49
    • (2012) J. Psychopharmacol , vol.26 , pp. 144-149
    • Stokes, P.R.1    Egerton, A.2    Watson, B.3    Reid, A.4    Lappin, J.5
  • 122
    • 67949121758 scopus 로고    scopus 로고
    • Can recreational doses of THC produce significant dopamine release in the human striatum?
    • Stokes PR, Mehta MA, Curran HV, Breen G, Grasby PM 2009. Can recreational doses of THC produce significant dopamine release in the human striatum? NeuroImage 48:186-90
    • (2009) NeuroImage , vol.48 , pp. 186-190
    • Stokes, P.R.1    Mehta, M.A.2    Curran, H.V.3    Breen, G.4    Grasby, P.M.5
  • 123
    • 84878958748 scopus 로고    scopus 로고
    • Predictors of a clinical high risk status among individuals with a family history of psychosis
    • Stowkowy J, Addington J. 2013. Predictors of a clinical high risk status among individuals with a family history of psychosis. Schizophr. Res. 147:281-86
    • (2013) Schizophr. Res , vol.147 , pp. 281-286
    • Stowkowy, J.1    Addington, J.2
  • 124
    • 34247642751 scopus 로고    scopus 로고
    • Spurious genetic associations
    • Sullivan PF. 2007. Spurious genetic associations. Biol. Psychiatry 61:1121-26
    • (2007) Biol. Psychiatry , vol.61 , pp. 1121-1126
    • Sullivan, P.F.1
  • 125
    • 84862776963 scopus 로고    scopus 로고
    • Dopamine release in chronic cannabis users: A [11c]raclopride positron emission tomography study
    • Urban NB, Slifstein M, Thompson JL, Xu X, Girgis RR, et al. 2012. Dopamine release in chronic cannabis users: A [11c]raclopride positron emission tomography study. Biol. Psychiatry 71:677-83
    • (2012) Biol. Psychiatry , vol.71 , pp. 677-683
    • Urban, N.B.1    Slifstein, M.2    Thompson, J.L.3    Xu, X.4    Girgis, R.R.5
  • 126
    • 64849096860 scopus 로고    scopus 로고
    • A systematic review and metaanalysis of the psychosis continuum: Evidence for a psychosis proneness-persistence-impairment model of psychotic disorder
    • van Os J, Linscott RJ, Myin-Germeys I, Delespaul P, Krabbendam L. 2009. A systematic review and metaanalysis of the psychosis continuum: Evidence for a psychosis proneness-persistence-impairment model of psychotic disorder. Psychol. Med. 39:179-95
    • (2009) Psychol. Med , vol.39 , pp. 179-195
    • Van Os, J.1    Linscott, R.J.2    Myin-Germeys, I.3    Delespaul, P.4    Krabbendam, L.5
  • 127
    • 54249166128 scopus 로고    scopus 로고
    • Gene-environment interactions in schizophrenia: Review of epidemiological findings and future directions
    • van Os J, Rutten BP, Poulton R. 2008. Gene-environment interactions in schizophrenia: Review of epidemiological findings and future directions. Schizophr. Bull. 34:1066-82
    • (2008) Schizophr. Bull , vol.34 , pp. 1066-1082
    • Van Os, J.1    Rutten, B.P.2    Poulton, R.3
  • 128
    • 77956400455 scopus 로고    scopus 로고
    • Genome-wide findings in schizophrenia and the role of gene-environment interplay
    • vanWinkel R, Esquivel G, Kenis G, Wichers M, Collip D, et al. 2010. Genome-wide findings in schizophrenia and the role of gene-environment interplay. CNS Neurosci. Ther. 16:e185-92
    • (2010) CNS Neurosci. Ther , vol.16
    • Vanwinkel, R.1    Esquivel, G.2    Kenis, G.3    Wichers, M.4    Collip, D.5
  • 129
    • 79951472497 scopus 로고    scopus 로고
    • Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: Sibling analysis and proband follow-up
    • Genetic Risk Outcome Psychos. (GROUP Investig
    • van Winkel R, Genetic Risk Outcome Psychos. (GROUP) Investig. 2011. Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: Sibling analysis and proband follow-up. Arch. Gen. Psychiatry 68:148-57
    • (2011) Arch. Gen. Psychiatry , vol.68 , pp. 148-157
    • Van Winkel, R.1
  • 130
    • 84897384722 scopus 로고    scopus 로고
    • Family-based study examiningmoderation of familial correlation in psychosis-related experiences by the environment
    • Genetic Risk Outcome Psychos. (GROUP) Investig
    • vanWinkel R, Genetic Risk Outcome Psychos. (GROUP) Investig. 2013. Family-based study examiningmoderation of familial correlation in psychosis-related experiences by the environment. Manuscr. submitted
    • (2013) Manuscr. Submitted
    • Vanwinkel, R.1
  • 131
    • 80054753550 scopus 로고    scopus 로고
    • AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder
    • Genetic Risk Outcome Psychos. (GROUP Investig
    • vanWinkel R, van Beveren JM, Genetic Risk Outcome Psychos. (GROUP) Investig. 2011. AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder. Neuropsychopharmacology 36:2529-37
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2529-2537
    • Vanwinkel, R.1    Van Beveren, J.M.2
  • 132
    • 48749133318 scopus 로고    scopus 로고
    • Cannabis use and genetic predisposition for schizophrenia: A case-control study
    • Veling W, Mackenbach JP, van Os J, HoekHW.2008. Cannabis use and genetic predisposition for schizophrenia: A case-control study. Psychol. Med. 38:1251-56
    • (2008) Psychol. Med , vol.38 , pp. 1251-1256
    • Veling, W.1    MacKenbach, J.P.2    Van Os, J.3    Hoek, H.W.4
  • 134
    • 84884135824 scopus 로고    scopus 로고
    • The effect of childhood maltreatment and cannabis use on adult psychotic symptoms is modified by theCOMTVal158Met polymorphism
    • Vinkers C, Van Gastel WA, Schubart CD, Van Eijk K, Luykx J, et al. 2013. The effect of childhood maltreatment and cannabis use on adult psychotic symptoms is modified by theCOMTVal158Met polymorphism. Schizophr. Res. 150:303-11
    • (2013) Schizophr. Res , vol.150 , pp. 303-311
    • Vinkers, C.1    Van Gastel, W.A.2    Schubart, C.D.3    Van Eijk, K.4    Luykx, J.5
  • 136
    • 58249139081 scopus 로고    scopus 로고
    • Behavioural disturbances and altered Fos protein expression in adult rats after chronic pubertal cannabinoid treatment
    • Wegener N, Koch M. 2009. Behavioural disturbances and altered Fos protein expression in adult rats after chronic pubertal cannabinoid treatment. Brain Res. 1253:81-91
    • (2009) Brain Res , vol.1253 , pp. 81-91
    • Wegener, N.1    Koch, M.2
  • 137
    • 0033838024 scopus 로고    scopus 로고
    • Brain morphological changes and early marijuana use: A magnetic resonance and positron emission tomography study
    • Wilson W, Mathew R, Turkington T, Hawk T, Coleman RE, Provenzale J. 2000. Brain morphological changes and early marijuana use: A magnetic resonance and positron emission tomography study. J. Addict. Dis. 19:1-22
    • (2000) J. Addict. Dis , vol.19 , pp. 1-22
    • Wilson, W.1    Mathew, R.2    Turkington, T.3    Hawk, T.4    Coleman, R.E.5    Provenzale, J.6
  • 138
    • 79956035968 scopus 로고    scopus 로고
    • Modulation of auditory and visual processing by delta-9- Tetrahydrocannabinol and cannabidiol: An FMRI study
    • Winton-Brown TT, Allen P, Bhattacharyya S, Borgwardt SJ, Fusar-Poli P, et al. 2011. Modulation of auditory and visual processing by delta-9- Tetrahydrocannabinol and cannabidiol: An FMRI study. Neuropsychopharmacology 36:1340-48
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1340-1348
    • Winton-Brown, T.T.1    Allen, P.2    Bhattacharyya, S.3    Borgwardt, S.J.4    Fusar-Poli, P.5
  • 139
    • 84857572453 scopus 로고    scopus 로고
    • The impact of cannabis use on cognitive functioning in patients with schizophrenia: A meta-Analysis of existing findings and new data in a firstepisode sample
    • Yücel M, Bora E, Lubman DI, Solowij N, Brewer WJ, et al. 2012. The impact of cannabis use on cognitive functioning in patients with schizophrenia: A meta-Analysis of existing findings and new data in a firstepisode sample. Schizophr. Bull. 38:316-30
    • (2012) Schizophr. Bull , vol.38 , pp. 316-330
    • Yücel, M.1    Bora, E.2    Lubman, D.I.3    Solowij, N.4    Brewer, W.J.5
  • 142
    • 35948986314 scopus 로고    scopus 로고
    • Genotype effects of CHRNA7,CNR1 and COMT in schizophrenia: Interactions with tobacco and cannabis use
    • Zammit S, Spurlock G, Williams H, Norton N, Williams N, et al. 2007. Genotype effects of CHRNA7,CNR1 and COMT in schizophrenia: Interactions with tobacco and cannabis use. Br. J. Psychiatry 191:402-7
    • (2007) Br. J. Psychiatry , vol.191 , pp. 402-407
    • Zammit, S.1    Spurlock, G.2    Williams, H.3    Norton, N.4    Williams, N.5
  • 143
    • 84870833786 scopus 로고    scopus 로고
    • A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation
    • Zuardi AW, Crippa JA, Hallak JE, Bhattacharyya S, Atakan Z, et al. 2012. A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation. Curr. Pharm. Des. 18:5131-40.
    • (2012) Curr. Pharm. des , vol.18 , pp. 5131-5140
    • Zuardi, A.W.1    Crippa, J.A.2    Hallak, J.E.3    Bhattacharyya, S.4    Atakan, Z.5


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