Engineering pre-SUMO4 as efficient substrate of SENP2

Protein Engineering, Design and Selection

Volumn 27, Issue 4, 2014, Pages 117-126

  Liu, Yan ^a   Kieslich, Chris A ^a   Morikis, Dimitrios ^a   Liao, Jiayu ^a  

^a University of California Riverside   (United States)

Author keywords

Computational modeling of electrostatic similarities; FRET based kinetics determination; protease substrate engineering; SUMO4 2; SUMOylation

Indexed keywords

AMINO ACIDS; ELECTROSTATICS; PROTEINS;

COMPUTATIONAL MODEL; FRET-BASED KINETICS DETERMINATION; SUBSTRATE ENGINEERING; SUMO4/2; SUMOYLATION;

SUBSTRATES;

AMINO ACID; PRE SUMO 4 PROTEIN; PROTEINASE; SENTRIN SPECIFIC PROTEASE 2; SUMO 1 PROTEIN; SUMO 2 PROTEIN; SUMO PROTEIN; UNCLASSIFIED DRUG; CYSTEINE PROTEINASE; SENP2 PROTEIN, HUMAN; SUMO2 PROTEIN, HUMAN; SUMO4 PROTEIN, HUMAN;

ARTICLE; COMPUTATIONAL FLUID DYNAMICS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SUBSTRATE; FLUORESCENCE RESONANCE ENERGY TRANSFER; INSULIN DEPENDENT DIABETES MELLITUS; KINETICS; MUTAGENESIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; SUMOYLATION; WESTERN BLOTTING; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MUTATION; PROCEDURES; PROTEIN CONFORMATION; STATIC ELECTRICITY;

CYSTEINE ENDOPEPTIDASES; FLUORESCENCE RESONANCE ENERGY TRANSFER; KINETICS; MODELS, MOLECULAR; MUTAGENESIS; MUTATION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN PROCESSING, POST-TRANSLATIONAL; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; STATIC ELECTRICITY;

EID: 84897439351     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzu004     Document Type: Article

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