Pharmacokinetics study of arteether loaded solid lipid nanoparticles: An improved oral bioavailability in rats

International Journal of Pharmaceutics

Volumn 466, Issue 1-2, 2014, Pages 321-327

  Dwivedi, Pankaj ^a   Khatik, Renuka ^a   Khandelwal, Kiran ^a   Taneja, Isha ^a   Raju, Kanumuri Siva Rama ^a   Wahajuddin, ^a   Paliwal, Sarvesh Kumar ^b   Dwivedi, Anil Kumar ^a   Mishra, Prabhat Ranjan ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b BANASTHALI UNIVERSITY   (India)

Author keywords

Arteether; High pressure homogenizer; LC MS; Pharmacokinetics; SLN

Indexed keywords

ARACHIS OIL; ARTEETHER; PHOSPHATIDYLCHOLINE; POLOXAMER; POLYSORBATE 80; SOLID LIPID NANOPARTICLE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; LIPID; NANOPARTICLE; SURFACTANT;

ADULT; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG DEGRADATION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MACROPHAGE; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PHARMACOKINETICS; PRIORITY JOURNAL; RAT; STOMACH; TIME TO MAXIMUM PLASMA CONCENTRATION; TRANSMISSION ELECTRON MICROSCOPY; YOUNG ADULT; ZETA POTENTIAL; ANIMAL; BIOAVAILABILITY; BLOOD; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; MOUSE; ORAL DRUG ADMINISTRATION; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ADMINISTRATION, ORAL; ANIMALS; ANTIMALARIALS; ARTEMISININS; BIOLOGICAL AVAILABILITY; CELL LINE, TUMOR; CELL SURVIVAL; LIPIDS; MALE; MICE; NANOPARTICLES; RATS, SPRAGUE-DAWLEY; SURFACE-ACTIVE AGENTS;

EID: 84897430096     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.03.036     Document Type: Article

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