Rad GTPase inhibits the NFκB pathway through interacting with RelA/p65 to impede its DNA binding and target gene transactivation

Cellular Signalling

Volumn 26, Issue 7, 2014, Pages 1437-1444

  Hsiao, Bo Yuan ^a   Chang, Tsun Kai ^a   Wu, I Ting ^a   Chen, Mei Yu ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

GTPase; NF B; Rad; RelA p65; TNF

Indexed keywords

GELATINASE B; GUANOSINE TRIPHOSPHATASE; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN 14 3 3; RAD PROTEIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; I KAPPA B KINASE; MMP9 PROTEIN, HUMAN; PROTEIN BINDING; RAS PROTEIN; RELA PROTEIN, HUMAN; RRAD PROTEIN, HUMAN; SMALL INTERFERING RNA;

ARTICLE; CELL INVASION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DNA BINDING; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; OLIGONUCLEOTIDE PROBE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION; TRANSCRIPTION REGULATION; UPREGULATION; BIOSYNTHESIS; DNA RESPONSIVE ELEMENT; GENETICS; LUNG TUMOR; METABOLISM; PATHOLOGY; RNA INTERFERENCE; TRANSCRIPTION INITIATION; TUMOR CELL LINE; TUMOR INVASION;

14-3-3 PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; I-KAPPA B KINASE; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; PROTEIN BINDING; RAS PROTEINS; RESPONSE ELEMENTS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR RELA; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84897425043     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.03.003     Document Type: Article

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