A new paradigm for developing antiviral drugs exemplified by the development of supremely high anti-HIV active EFdA

Journal of Antivirals and Antiretrovirals

Volumn 6, Issue 1, 2014, Pages 32-39

  Ohrui, Hiroshi ^a  

^a YOKOHAMA COLLEGE OF PHARMACY   (Japan)

Author keywords

4' C substituted 2' deoxynucleosid; Anti HIV agent; Anti viral drug; Drug resistant HIV; Substrate selectivity of nucleic acid polymerase

Indexed keywords

2' DEOXYNUCLEOSIDE; 2',3' DIDEOXYNUCLEOSIDE; 4' C ETHYNYL 2'DEOXY 2 FLUOROADENOSINE; 4' C SUBSTITUTED 2' DEOXYNUCLEOSIDE DERIVATIVE; ANTIVIRUS AGENT; CYTIDINE DERIVATIVE; DNA POLYMERASE; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; RNA POLYMERASE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MTT ASSAY; MUTANT; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; THEORY VALIDATION;

EID: 84897422169     PISSN: None     EISSN: 19485964     Source Type: Journal    
DOI: 10.4172/jaa.1000092     Document Type: Article

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