2′-deoxy-4′- C-ethynyl-2-fluoroadenosine, a nucleoside reverse transcriptase inhibitor, is highly potent against all human immunodeficiency viruses type 1 and has low toxicity

Chemical Record

Volumn 6, Issue 3, 2006, Pages 133-143

  Ohrui, Hiroshi ^a  

^a YOKOHAMA COLLEGE OF PHARMACY   (Japan)

Author keywords

4 C substituted 2 deoxynucleoside; AIDS; Anti HIV agent; Drug resistant HIV; Highly active antiretroviral therapy; Nucleoside reverse transcriptase inhibitor; Reverse transcriptase

Indexed keywords

2' DEOXY 4' C ETHYNYL 2 FLUOROADENOSINE; 2'-DEOXY-4'-C-ETHYNYL-2-FLUOROADENOSINE; DEOXYADENOSINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ANIMAL; ANTIBIOTIC RESISTANCE; ARTICLE; CHEMISTRY; CONFORMATION; DRUG EFFECT; HUMAN IMMUNODEFICIENCY VIRUS 1; MICROBIOLOGICAL EXAMINATION; MOUSE; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING;

ACUTE TOXICITY TESTS; ANIMALS; DEOXYADENOSINES; DRUG RESISTANCE, VIRAL; HIV-1; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33746109349     PISSN: 15278999     EISSN: 15280691     Source Type: Journal    
DOI: 10.1002/tcr.20078     Document Type: Article

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