Chronic Exposure to Type-I IFN under Lymphopenic Conditions Alters CD4 T Cell Homeostasis

PLoS Pathogens

Volumn 10, Issue 3, 2014, Pages

  Le Saout, Cecile ^a   Hasley, Rebecca B ^a   Imamichi, Hiromi ^a   Tcheung, Lueng ^a   Hu, Zonghui ^a   Luckey, Megan A ^b   Park, Jung Hyun ^b   Durum, Scott K ^c   Smith, Mindy ^a   Rupert, Adam W ^d   Sneller, Michael C ^a   Lane, H Clifford ^a   Catalfamo, Marta ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; INTERFERON; INTERLEUKIN 7; STAT1 PROTEIN; STAT2 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HOMEOSTASIS; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; LYMPHOCYTE DEPLETION; LYMPHOCYTOPENIA; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; VIRUS LOAD; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; HIV INFECTIONS; HOMEOSTASIS; HUMANS; INTERFERON TYPE I; LYMPHOPENIA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 84897420506     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003976     Document Type: Article

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