Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury

Kidney International

Volumn 85, Issue 4, 2014, Pages 807-823

  Ham, Ahrom ^a   Kim, Mihwa ^a   Kim, Joo Yun ^a   Brown, Kevin M ^a   Fruttiger, Marcus ^b   Thomas Lee, H ^a  

^a New York Presbyterian Columbia University Medical Center   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Apoptosis; Cre recombinase; Inflammation; Necrosis; Tamoxifen

Indexed keywords

CRE RECOMBINASE; HEAT SHOCK PROTEIN 27; MESSENGER RNA; TAMOXIFEN; HSPB2 PROTEIN, MOUSE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; ALANINE AMINOTRANSFERASE; CD34 ANTIGEN; CREATININE; ENDOTHELIAL SPHINGOSINE 1 PHOSPHATE 1 RECEPTOR; HEAT SHOCK PROTEIN 70; HEME OXYGENASE 1; INTERCELLULAR ADHESION MOLECULE 1; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR B; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ADULT; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL SURVIVAL; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE EXACERBATION; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; GENE; GENE DELETION; GENE EXPRESSION REGULATION; HSP27 GENE; HUMAN; HUMAN CELL; KIDNEY NECROSIS; KIDNEY TUBULE NECROSIS; LIVER INJURY; LIVER NECROSIS; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PDGF BETA GENE; PRIORITY JOURNAL; REPERFUSION INJURY; S1P1R GENE; TRANSCRIPTION REGULATION; ANIMAL; C57BL MOUSE; CAPILLARY PERMEABILITY; ENDOTHELIUM; GENE EXPRESSION; GENE SILENCING; GENETICS; IMMUNOLOGY; KIDNEY; LIVER; LIVER DISEASE; METABOLISM; NECROSIS; PATHOLOGY; TRANSGENIC MOUSE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; COMPARATIVE STUDY; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE SEVERITY; GENETIC ASSOCIATION; GLOMERULUS FILTRATION RATE; HISTOPATHOLOGY; KIDNEY DISEASE; KIDNEY ISCHEMIA REPERFUSION INJURY; NEPHRITIS; PDGFB GENE; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; RECEPTOR BLOCKING; RENAL PROTECTION; UMBILICAL VEIN ENDOTHELIAL CELL; WILD TYPE;

ACUTE KIDNEY INJURY; ANIMALS; APOPTOSIS; CAPILLARY PERMEABILITY; ENDOTHELIAL CELLS; ENDOTHELIUM; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HSP27 HEAT-SHOCK PROTEINS; KIDNEY; LIVER; LIVER DISEASES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NECROSIS; NEUTROPHIL INFILTRATION; RECEPTORS, LYSOSPHINGOLIPID; REPERFUSION INJURY;

EID: 84897409696     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.345     Document Type: Article

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