Efficient, inducible cre-recombinase activation in vascular endothelium

Genesis

Volumn 46, Issue 2, 2008, Pages 74-80

  Claxton, Suzanne ^a   Kostourou, Vassiliki ^b   Jadeja, Shalini ^c   Chambon, Pierre ^d   Hodivala Dilke, Kairbaan ^b   Fruttiger, Marcus ^c  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Blood vessels; Cre recominase; Endothelial cells; Tamoxifen; Transgenic mice

Indexed keywords

CRE RECOMBINASE; PLATELET DERIVED GROWTH FACTOR B; TAMOXIFEN; INTEGRASE;

ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE SEQUENCE; GENE TARGETING; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; VASCULAR ENDOTHELIUM; ANIMAL; CYTOLOGY; EMBRYO (ANATOMY); GENE EXPRESSION REGULATION; GENETIC PROCEDURES; GENETICS; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PROTO ONCOGENE; TRANSGENIC MOUSE;

ANIMALIA; MUS; MUS MUSCULUS;

ANIMALS; EMBRYO, MAMMALIAN; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, SIS; GENETIC TECHNIQUES; INTEGRASES; MICE; MICE, TRANSGENIC; NEOVASCULARIZATION, PATHOLOGIC; TAMOXIFEN;

EID: 39549098360     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20367     Document Type: Article

References (22)

1. Beer HD, Longaker MT, Werner S. 1997. Reduced expression of PDGF and PDGF receptors during impaired wound healing. J Invest Dermatol 109:132-138.
2. Claxton S, Fruttiger M. 2004. Periodic delta-like 4 expression in developing retinal arteries. Gene Expr Patterns 5:123-127.
3. Feil R, Wagner J, Metzger D, Chambon P. 1997. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem Biophys Res Commun 237:752-757.
4. Fogarty M, Richardson WD, Kessaris N. 2005. A subset of oligodendrocytes generated from radial glia in the dorsal spinal cord. Development 132:1951-1959.
5. Forde A, Constien R, Grone HJ, Hammerling G, Arnold B. 2002. Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements. Genesis 33:191-197.
6. Fruttiger M. 2002. Development of the mouse retinal vasculature: Angiogenesis versus vasculogenesis. Invest Ophthalmol Vis Sci 43:522-527.
7. Gerhardt H, Golding M, Fruttiger M, Ruhrberg C, Lundkvist A, Abramsson A, Jeltsch M, Mitchell C, Alitalo K, Shima D, Betsholtz C. 2003. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol 161:1163-1177.
8. Gladwin AM, Carrier MJ, Beesley JE, Lelchuk R, Hancock V, Martin JF. 1990. Identification of mRNA for PDGF B-chain in human megakaryocytes isolated using a novel immunomagnetic separation method. Br J Haematol 76:333-339.
9. Gothert JR, Gustin SE, van Eekelen JA, Schmidt U, Hall MA, Jane SM, Green AR, Gottgens B, Izon DJ, Begley CG. 2004. Genetically tagging endothelial cells in vivo: Bone marrow-derived cells do not contribute to tumor endothelium. Blood 104:1769-1777.
10. Hellstrom M, Kaln M, Lindahl P, Abramsson A, Betsholtz C. 1999. Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development 126:3047-3055.
11. Kaminski WE, Lindahl P, Lin NL, Broudy VC, Crosby JR, Hellstrom M, Swolin B, Bowen-Pope DF, Martin PJ, Ross R, Betsholtz C, Raines EW. 2001. Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice. Blood 97:1990-1998.
12. Kozak M. 1987. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res 15:8125-8148.
13. Lindahl P, Johansson BR, Leveen P, Betsholtz C. 1997. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 277:242-245.
14. Metzger D, Clifford J, Chiba H, Chambon P. 1995. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc Natl Acad Sci USA 92:6991-6995.
15. Monvoisin A, Alva JA, Hofmann JJ, Zovein AC, Lane TF, Iruela-Arispe ML. 2006. VE-cadherin-CreER(T2) transgenic mouse: A model for inducible recombination in the endothelium. Dev Dyn 235:3413-3422.
16. Osoegawa K, de Jong PJ. 2004. BAC library construction. Methods Mol Biol 255:1-46.
17. Scherrer LC, Picard D, Massa E, Harmon JM, Simons SS, Jr., Yamamoto KR, Pratt WB. 1993. Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90. Biochemistry 32:5381-5386.
18. Shimshek DR, Kim J, Hubner MR, Spergel DJ, Buchholz F, Casanova E, Stewart AF, Seeburg PH, Sprengel R. 2002. Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis 32:19-26.
19. Soriano P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71.
20. West H, Richardson WD, Fruttiger M. 2005. Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes. Development 132:1855-1862.
21. Wilson E, Mai Q, Sudhir K, Weiss RH, Ives HE. 1993. Mechanical strain induces growth of vascular smooth muscle cells via autocrine action of PDGE J. Cell Biol 123:741-747.
22. Yu D, Ellis HM, Lee EC, Jenkins NA, Copeland NG, Court DL. 2000. An efficient recombination system for chromosome engineering in Escherichia coli. Proc Natl Acad Sci USA 97:5978-5983.