Effect of initial pBMP-9 loading and collagen concentration on the kinetics of peptide release and a mathematical model of the delivery system

Journal of Controlled Release

Volumn 182, Issue 1, 2014, Pages 73-82

  Lauzon, Marc Antoine ^a   Marcos, Bernard ^a   Faucheux, Nathalie ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Bone regeneration; Electrostatic interactions; Mass transport; Peptides

Indexed keywords

COLLAGEN; COULOMB INTERACTIONS; DRUG DELIVERY; KINETICS; MASS TRANSFER; MATHEMATICAL MODELS; PEPTIDES; TISSUE; TISSUE REGENERATION; TRANSMISSION ELECTRON MICROSCOPY;

BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; COLLAGEN CONCENTRATION; FICK'S SECOND LAW; LANGMUIR ADSORPTION; LANGMUIR ISOTHERM; OSTEOGENIC DIFFERENTIATION; PARAMETERS ESTIMATED;

LOADING;

BONE MORPHOGENETIC PROTEIN 9; COLLAGEN; COLLAGEN FIBER; COLLAGEN GEL; COLLAGEN TYPE 1; TROPOCOLLAGEN; HYDROGEL; PEPTIDE;

ADSORPTION; ARTICLE; BINDING AFFINITY; BONE DEVELOPMENT; BONE REGENERATION; BOUNDARY LAYER; CELL DIFFERENTIATION; CONTROLLED STUDY; DESORPTION; DIFFUSION; DRUG DELIVERY SYSTEM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEL; IN VITRO STUDY; ISOTHERM; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; STATIC ELECTRICITY; SUSTAINED DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY; CHEMISTRY; KINETICS; THEORETICAL MODEL;

COLLAGEN TYPE I; DRUG DELIVERY SYSTEMS; GROWTH DIFFERENTIATION FACTOR 2; HYDROGELS; KINETICS; MODELS, THEORETICAL; PEPTIDES;

EID: 84897370609     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.03.008     Document Type: Article

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