Neuroprotective effects of tetramethylpyrazine against dopaminergic neuron injury in a rat model of parkinson's disease induced by MPTP

International Journal of Biological Sciences

Volumn 10, Issue 4, 2014, Pages 350-357

  Lu, Chen ^a,e   Zhang, Jin ^b   Shi, Xiaopeng ^c   Miao, Shan ^a,e   Bi, Linlin ^a,e   Zhang, Song ^d   Yang, Qian ^a,e   Zhou, Xuanxuan ^a,e   Zhang, Meng ^a,e   Xie, Yanhua ^a,e   Miao, Qing ^a,e   Wang, Si Wang ^a,e  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b 401 Military Hospital   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^e The Cultivation Project of Collaborative Innovation Center for Chinese Medicine in QinBa Mountains   (China)

Author keywords

Anti apoptotic; Antioxidant; MPTP; Parkinson's disease; Tetramethylpyrazine

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CASPASE 3; CYTOCHROME C; DOPAMINE; GCLC PROTEIN, RAT; GLUTAMATE CYSTEINE LIGASE; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, RAT; PROTEIN BAX; PROTEIN BCL 2; PYRAZINE DERIVATIVE; TETRAMETHYLPYRAZINE; TRANSCRIPTION FACTOR NRF2;

ANIMAL; APOPTOSIS; DISEASE MODEL; DOPAMINERGIC NERVE CELL; DOWN REGULATION; DRUG EFFECTS; GENETICS; MALE; METABOLISM; MPTP POISONING; OXIDATIVE STRESS; PATHOLOGY; UPREGULATION; WISTAR RAT;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CYTOCHROMES C; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINERGIC NEURONS; DOWN-REGULATION; GLUTAMATE-CYSTEINE LIGASE; MALE; MPTP POISONING; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRAZINES; RATS, WISTAR; UP-REGULATION;

EID: 84897092218     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.8366     Document Type: Article

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