-
1
-
-
24344446871
-
Diagnosis and initial management of Parkinson's disease
-
DOI 10.1056/NEJMcp043908
-
J.G. Nutt, and G.F. Wooten Clinical practice. Diagnosis and initial management of Parkinson's disease N Engl J Med 353 2005 1021 1027 (Pubitemid 41262336)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.10
, pp. 1021-1027
-
-
Nutt, J.G.1
Wooten, G.F.2
-
2
-
-
34250624810
-
A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases
-
DOI 10.1242/jcs.03443
-
W. Mandemakers, V.A. Morais, and B. De Strooper A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases J Cell Sci 120 2007 1707 1716 (Pubitemid 46930408)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.10
, pp. 1707-1716
-
-
Mandemakers, W.1
Morais, V.A.2
De Strooper, B.3
-
3
-
-
33748602367
-
Genetic testing in Parkinson disease: Promises and pitfalls
-
DOI 10.1001/archneur.63.9.1232
-
E.K. Tan, and J. Jankovic Genetic testing in Parkinson disease: promises and pitfalls Arch Neurol 63 2006 1232 1237 (Pubitemid 44379821)
-
(2006)
Archives of Neurology
, vol.63
, Issue.9
, pp. 1232-1237
-
-
Tan, E.-K.1
Jankovic, J.2
-
4
-
-
33750475625
-
Free radicals, mitochondria, and oxidized lipids: The emerging role in signal transduction in vascular cells
-
DOI 10.1161/01.RES.0000248212.86638.e9, PII 0000301220061027000005
-
J. Gutierrez, S.W. Ballinger, V.M. Darley-Usmar, and A. Landar Free radicals, mitochondria, and oxidized lipids: the emerging role in signal transduction in vascular cells Circ Res 99 2006 924 932 (Pubitemid 44657795)
-
(2006)
Circulation Research
, vol.99
, Issue.9
, pp. 924-932
-
-
Gutierrez, J.1
Ballinger, S.W.2
Darley-Usmar, V.M.3
Landar, A.4
-
5
-
-
26444486315
-
Comparison of bilaterally 6-OHDA- and MPTP-lesioned rats as models of the early phase of Parkinson's disease: Histological, neurochemical, motor and memory alterations
-
DOI 10.1016/j.jneumeth.2005.04.005, PII S0165027005001123
-
M.M. Ferro, M.I. Bellissimo, J.A. Anselmo-Franci, M.E. Angellucci, N.S. Canteras, and C. Da Cunha Comparison of bilaterally 6-OHDA- and MPTP-lesioned rats as models of the early phase of Parkinson's disease: histological, neurochemical, motor and memory alterations J Neurosci Methods 148 2005 78 87 (Pubitemid 41423461)
-
(2005)
Journal of Neuroscience Methods
, vol.148
, Issue.1
, pp. 78-87
-
-
Ferro, M.M.1
Bellissimo, M.I.2
Anselmo-Franci, J.A.3
Angellucci, M.E.M.4
Canteras, N.S.5
Da Cunha, C.6
-
6
-
-
1642440103
-
Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine in the mouse nigrostriatum
-
DOI 10.1046/j.1600-079X.2003.00096.x
-
B. Thomas, and K.P. Mohanakumar Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the mouse nigrostriatum J Pineal Res 36 2004 25 32 (Pubitemid 38130286)
-
(2004)
Journal of Pineal Research
, vol.36
, Issue.1
, pp. 25-32
-
-
Thomas, B.1
Mohanakumar, K.P.2
-
7
-
-
58149506251
-
Centella asiatica extract selectively decreases amyloid beta levels in hippocampus of Alzheimer's disease animal model
-
M. Dhanasekaran, L.A. Holcomb, A.R. Hitt, B. Tharakan, J.W. Porter, and K.A. Young Centella asiatica extract selectively decreases amyloid beta levels in hippocampus of Alzheimer's disease animal model Phytother Res 23 2009 14 19
-
(2009)
Phytother Res
, vol.23
, pp. 14-19
-
-
Dhanasekaran, M.1
Holcomb, L.A.2
Hitt, A.R.3
Tharakan, B.4
Porter, J.W.5
Young, K.A.6
-
8
-
-
35348861285
-
Beneficial effects of Centella asiatica aqueous extract against arsenic-induced oxidative stress and essential metal status in rats
-
DOI 10.1002/ptr.2208
-
S.J. Flora, and R. Gupta Beneficial effects of Centella asiatica aqueous extract against arsenic-induced oxidative stress and essential metal status in rats Phytother Res 21 2007 980 988 (Pubitemid 47582774)
-
(2007)
Phytotherapy Research
, vol.21
, Issue.10
, pp. 980-988
-
-
Flora, S.J.S.1
Gupta, R.2
-
9
-
-
76749084818
-
Neuroprotective effect of Centella asiatica extract (CAE) on experimentally induced parkinsonism in aged Sprague-Dawley rats
-
N. Haleagrahara, and K. Ponnusamy Neuroprotective effect of Centella asiatica extract (CAE) on experimentally induced parkinsonism in aged Sprague-Dawley rats J Toxicol Sci 35 2010 41 47
-
(2010)
J Toxicol Sci
, vol.35
, pp. 41-47
-
-
Haleagrahara, N.1
Ponnusamy, K.2
-
10
-
-
79954420880
-
Protective effect of Zhen-Wu-Tang (ZWT) through keeping da stable and VMAT 2/DAT mRNA in balance in rats with striatal lesions induced by MPTP
-
X.M. Li, C.L. Xu, J.M. Deng, L.F. Li, S.P. Ma, and R. Qu Protective effect of Zhen-Wu-Tang (ZWT) through keeping DA stable and VMAT 2/DAT mRNA in balance in rats with striatal lesions induced by MPTP J Ethnopharmacol 134 2011 768 774
-
(2011)
J Ethnopharmacol
, vol.134
, pp. 768-774
-
-
Li, X.M.1
Xu, C.L.2
Deng, J.M.3
Li, L.F.4
Ma, S.P.5
Qu, R.6
-
11
-
-
0034088256
-
Reactive oxygen species-induced apoptosis in PC12 cells and protective effect of bilobalide
-
L.J. Zhou, and X.Z. Zhu Reactive oxygen species-induced apoptosis in PC12 cells and protective effect of bilobalide J Pharmacol Exp Ther 293 2000 982 988 (Pubitemid 30417867)
-
(2000)
Journal of Pharmacology and Experimental Therapeutics
, vol.293
, Issue.3
, pp. 982-988
-
-
Zhou, L.-J.1
Zhu, X.Z.2
-
12
-
-
47749136270
-
The hairless phenotype of the Hirosaki hairless rat is due to the deletion of an 80-kb genomic DNA containing five basic keratin genes
-
N. Nanashima, M. Akita, T. Yamada, T. Shimizu, H. Nakano, and Y. Fan The hairless phenotype of the Hirosaki hairless rat is due to the deletion of an 80-kb genomic DNA containing five basic keratin genes J Biol Chem 283 2008 16868 16875
-
(2008)
J Biol Chem
, vol.283
, pp. 16868-16875
-
-
Nanashima, N.1
Akita, M.2
Yamada, T.3
Shimizu, T.4
Nakano, H.5
Fan, Y.6
-
13
-
-
46749109164
-
+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease
-
DOI 10.1096/fj.07-095398
-
N.P. Visanji, A. Orsi, T.H. Johnston, P.A. Howson, K. Dixon, and N. Callizot PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP + in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease FASEB J 22 2008 2488 2497 (Pubitemid 351948666)
-
(2008)
FASEB Journal
, vol.22
, Issue.7
, pp. 2488-2497
-
-
Visanji, N.P.1
Orsi, A.2
Johnston, T.H.3
Howson, P.A.4
Dixon, K.5
Callizot, N.6
Brotchie, J.M.7
Rees, D.D.8
-
14
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 1976 248 254
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
15
-
-
34247359586
-
An orally active catalytic metalloporphyrin protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in vivo
-
DOI 10.1523/JNEUROSCI.0019-07.2007
-
L.P. Liang, J. Huang, R. Fulton, B.J. Day, and M. Patel An orally active catalytic metalloporphyrin protects against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity in vivo J Neurosci Off J Soc Neurosci 27 2007 4326 4333 (Pubitemid 46640723)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.16
, pp. 4326-4333
-
-
Liang, L.-P.1
Huang, J.2
Fulton, R.3
Day, B.J.4
Patel, M.5
-
16
-
-
0024585155
-
Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease
-
DOI 10.1111/j.1471-4159.1989.tb09133.x
-
D.T. Dexter, C.J. Carter, F.R. Wells, F. Javoy-Agid, Y. Agid, and A. Lees Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease J Neurochem 52 1989 381 389 (Pubitemid 19037600)
-
(1989)
Journal of Neurochemistry
, vol.52
, Issue.2
, pp. 381-389
-
-
Dexter, D.T.1
Carter, C.J.2
Wells, F.R.3
Javoy-Agid, F.4
Agid, Y.5
Lees, A.6
Jenner, P.7
Marsden, C.D.8
-
17
-
-
0030805622
-
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
-
Z.I. Alam, S.E. Daniel, A.J. Lees, D.C. Marsden, P. Jenner, and B. Halliwell A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease J Neurochem 69 1997 1326 1329 (Pubitemid 27364859)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.3
, pp. 1326-1329
-
-
Alam, Z.I.1
Daniel, S.E.2
Lees, A.J.3
Marsden, D.C.4
Jenner, P.5
Halliwell, B.6
-
19
-
-
0027952849
-
Increased levels of lipid hydroperoxides in the Parkinsonian Substantia nigra: An HPLC and ESR study
-
DOI 10.1002/mds.870090115
-
D.T. Dexter, A.E. Holley, W.D. Flitter, T.F. Slater, F.R. Wells, and S.E. Daniel Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study Mov Disord 9 1994 92 97 (Pubitemid 24022621)
-
(1994)
Movement Disorders
, vol.9
, Issue.1
, pp. 92-97
-
-
Dexter, D.T.1
Holley, A.E.2
Flitter, W.D.3
Slater, T.F.4
Wells, F.R.5
Daniel, S.E.6
Lees, A.J.7
Jenner, P.8
Marsden, C.D.9
-
20
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
H. Esterbauer, R.J. Schaur, and H. Zollner Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes Free Radic Biol Med 11 1991 81 128 (Pubitemid 121003917)
-
(1991)
Free Radical Biology and Medicine
, vol.11
, Issue.1
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
21
-
-
0035003439
-
Chemistry and biochemistry of oxidative stress in neurodegenerative disease
-
L.M. Sayre, M.A. Smith, and G. Perry Chemistry and biochemistry of oxidative stress in neurodegenerative disease Curr Med Chem 8 2001 721 738 (Pubitemid 32427903)
-
(2001)
Current Medicinal Chemistry
, vol.8
, Issue.7
, pp. 721-738
-
-
Sayre, L.M.1
Smith, M.A.2
Perry, G.3
-
23
-
-
0022525619
-
Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutathione in the extrapyramidal system of the mouse
-
DOI 10.1016/0028-3908(86)90205-4
-
T.N. Ferraro, G.T. Golden, M. DeMattei, T.A. Hare, and R.G. Fariello Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutathione in the extrapyramidal system of the mouse Neuropharmacology 25 1986 1071 1074 (Pubitemid 16050472)
-
(1986)
Neuropharmacology
, vol.25
, Issue.9
, pp. 1071-1074
-
-
Ferraro, T.N.1
Golden, G.T.2
DeMattei, M.3
-
24
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
A. Gross, J.M. McDonnell, and S.J. Korsmeyer BCL-2 family members and the mitochondria in apoptosis Genes Dev 13 1999 1899 1911 (Pubitemid 29407357)
-
(1999)
Genes and Development
, vol.13
, Issue.15
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
25
-
-
0032531886
-
1-methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2
-
L. Yang, R.T. Matthews, J.B. Schulz, T. Klockgether, A.W. Liao, and J.C. Martinou 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2 J Neurosci 18 1998 8145 8152 (Pubitemid 28464993)
-
(1998)
Journal of Neuroscience
, vol.18
, Issue.20
, pp. 8145-8152
-
-
Yang, L.1
Matthews, R.T.2
Schulz, J.B.3
Klockgether, T.4
Liao, A.W.5
Martinou, J.-C.6
Penney Jr., J.B.7
Hyman, B.T.8
Beal, M.F.9
-
26
-
-
0027717968
-
Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species
-
D.J. Kane, T.A. Sarafian, R. Anton, H. Hahn, E.B. Gralla, and J.S. Valentine Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species Science 262 1993 1274 1277 (Pubitemid 24036095)
-
(1993)
Science
, vol.262
, Issue.5137
, pp. 1274-1277
-
-
Kane, D.J.1
Sarafian, T.A.2
Anton, R.3
Hahn, H.4
Gralla, E.B.5
Valentine, J.S.6
Ord, T.7
Bredesen, D.E.8
-
27
-
-
0030754701
-
Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols
-
N. Mirkovic, D.W. Voehringer, M.D. Story, D.J. McConkey, T.J. McDonnell, and R.E. Meyn Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols Oncogene 15 1997 1461 1470 (Pubitemid 27437836)
-
(1997)
Oncogene
, vol.15
, Issue.12
, pp. 1461-1470
-
-
Mirkovic, N.1
Voehringer, D.W.2
Story, M.D.3
McConkey, D.J.4
McDonnell, T.J.5
Meyn, R.E.6
-
28
-
-
0035956874
-
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
DOI 10.1073/pnas.051633998
-
M. Vila, V. Jackson-Lewis, S. Vukosavic, R. Djaldetti, G. Liberatore, and D. Offen Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease Proc Natl Acad Sci U S A 98 2001 2837 2842 (Pubitemid 32209570)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.5
, pp. 2837-2842
-
-
Vila, M.1
Jackson-Lewis, V.2
Vukosavic, S.3
Djaldetti, R.4
Liberatore, G.5
Offen, D.6
Korsmeyer, S.J.7
Przedborski, S.8
-
29
-
-
0037443479
-
Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML)
-
DOI 10.1182/blood-2002-06-1714
-
G. Del Poeta, A. Venditti, M.I. Del Principe, L. Maurillo, F. Buccisano, and A. Tamburini Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML) Blood 101 2003 2125 2131 (Pubitemid 36302046)
-
(2003)
Blood
, vol.101
, Issue.6
, pp. 2125-2131
-
-
Del Poeta, G.1
Venditti, A.2
Del Principe, M.I.3
Maurillo, L.4
Buccisano, F.5
Tamburini, A.6
Cox, M.C.7
Franchi, A.8
Bruno, A.9
Mazzone, C.10
Panetta, P.11
Suppo, G.12
Masi, M.13
Amadori, S.14
-
30
-
-
68849083063
-
Brain-derived neurotrophic factor in neurodegenerative diseases
-
C. Zuccato, and E. Cattaneo Brain-derived neurotrophic factor in neurodegenerative diseases Nat Rev Neurol 5 2009 311 322
-
(2009)
Nat Rev Neurol
, vol.5
, pp. 311-322
-
-
Zuccato, C.1
Cattaneo, E.2
-
31
-
-
33645077925
-
BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD Study
-
S. Karamohamed, J.C. Latourelle, B.A. Racette, J.S. Perlmutter, G.F. Wooten, and M. Lew BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD Study Neurology 65 2005 1823 1825
-
(2005)
Neurology
, vol.65
, pp. 1823-1825
-
-
Karamohamed, S.1
Latourelle, J.C.2
Racette, B.A.3
Perlmutter, J.S.4
Wooten, G.F.5
Lew, M.6
-
32
-
-
0035239020
-
Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease
-
M.G. Murer, Q. Yan, and R. Raisman-Vozari Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease Prog Neurobiol 63 2001 71 124
-
(2001)
Prog Neurobiol
, vol.63
, pp. 71-124
-
-
Murer, M.G.1
Yan, Q.2
Raisman-Vozari, R.3
-
33
-
-
0026482150
-
Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo
-
C.A. Altar, C.B. Boylan, C. Jackson, S. Hershenson, J. Miller, and S.J. Wiegand Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo Proc Natl Acad Sci U S A 89 1992 11347 11351
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 11347-11351
-
-
Altar, C.A.1
Boylan, C.B.2
Jackson, C.3
Hershenson, S.4
Miller, J.5
Wiegand, S.J.6
-
34
-
-
0025876757
-
BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra
-
C. Hyman, M. Hofer, Y.A. Barde, M. Juhasz, G.D. Yancopoulos, and S.P. Squinto BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra Nature 350 1991 230 232 (Pubitemid 21912205)
-
(1991)
Nature
, vol.350
, Issue.6315
, pp. 230-232
-
-
Hyman, C.1
Hofer, M.2
Barde, Y.-A.3
Juhasz, M.4
Yancopoulos, G.D.5
Squinto, S.P.6
Lindsay, R.M.7
-
35
-
-
6944242126
-
Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members
-
DOI 10.1096/fj.04-1916fje
-
O. Weinreb, O. Bar-Am, T. Amit, O. Chillag-Talmor, and M.B. Youdim Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members FASEB J 18 2004 1471 1473 (Pubitemid 39561618)
-
(2004)
FASEB Journal
, vol.18
, Issue.12
, pp. 1471-1473
-
-
Weinreb, O.1
Bar-Am, O.2
Amit, T.3
Chillag-Talmor, O.4
Youdim, M.B.H.5
-
36
-
-
84865092868
-
Exercise does not protect against MPTP-induced neurotoxicity in BDNF happloinsufficient mice
-
K.M. Gerecke, Y. Jiao, V. Pagala, and R.J. Smeyne Exercise does not protect against MPTP-induced neurotoxicity in BDNF happloinsufficient mice PLoS One 7 2012 e43250
-
(2012)
PLoS One
, vol.7
, pp. 43250
-
-
Gerecke, K.M.1
Jiao, Y.2
Pagala, V.3
Smeyne, R.J.4
-
37
-
-
80051615232
-
Running wheel activity restores MPTP-induced functional deficits
-
A. Fredriksson, I.M. Stigsdotter, A. Hurtig, B. Ewalds-Kvist, and T. Archer Running wheel activity restores MPTP-induced functional deficits J Neural Transm 118 2011 407 420
-
(2011)
J Neural Transm
, vol.118
, pp. 407-420
-
-
Fredriksson, A.1
Stigsdotter, I.M.2
Hurtig, A.3
Ewalds-Kvist, B.4
Archer, T.5
-
38
-
-
56649124807
-
Glutamate and neurotrophic factors in neuronal plasticity and disease
-
M.P. Mattson Glutamate and neurotrophic factors in neuronal plasticity and disease Ann N Y Acad Sci 1144 2008 97 112
-
(2008)
Ann N y Acad Sci
, vol.1144
, pp. 97-112
-
-
Mattson, M.P.1
-
39
-
-
79959509244
-
Neuroprotective signaling mechanisms of telomerase are regulated by brain-derived neurotrophic factor in rat spinal cord motor neurons
-
C. Niu, and H.K. Yip Neuroprotective signaling mechanisms of telomerase are regulated by brain-derived neurotrophic factor in rat spinal cord motor neurons J Neuropathol Exp Neurol 70 2011 634 652
-
(2011)
J Neuropathol Exp Neurol
, vol.70
, pp. 634-652
-
-
Niu, C.1
Yip, H.K.2
-
40
-
-
58849164675
-
Parkinson-linked genes and toxins that affect neuronal cell death through the Bcl-2 family
-
D.W. Ethell, and Q. Fei Parkinson-linked genes and toxins that affect neuronal cell death through the Bcl-2 family Antioxid Redox Signal 11 2009 529 540
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 529-540
-
-
Ethell, D.W.1
Fei, Q.2
|