Immunization of pigs with an attenuated pseudorabies virus recombinant expressing the haemagglutinin of pandemic swine origin H1N1 influenza A virus

Journal of General Virology

Volumn 95, Issue PART 4, 2014, Pages 948-959

  Klingbeil, Katharina ^a   Lange, Elke ^a   Teifke, Jens P ^a   Mettenleiter, Thomas C ^a   Fuchs, Walter ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VIRUS HEMAGGLUTININ; LIVE VACCINE; PSEUDORABIES VIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CODON USAGE; CONTROLLED STUDY; DNA SEQUENCE; GENE EXPRESSION; GENE INSERTION; IMMUNE RESPONSE; IMMUNIZATION; INFLUENZA VIRUS A H1N1; NONHUMAN; PRIORITY JOURNAL; SWINE INFLUENZA; SWINE INFLUENZA VIRUS; TRANSGENE; VIRION; VIRUS LOAD; VIRUS REPLICATION; VIRUS SHEDDING;

ANIMALS; ANTIBODIES, VIRAL; DRUG CARRIERS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HERPESVIRUS 1, SUID; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA VACCINES; ORTHOMYXOVIRIDAE INFECTIONS; SWINE; SWINE DISEASES; VACCINES, ATTENUATED; VIRUS SHEDDING;

EID: 84897088079     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.059253-0     Document Type: Article

References (50)

1. Babiuk, S., Masic, A., Graham, J., Neufeld, J., van der Loop, M., Copps, J., Berhane, Y., Pasick, J., Potter, A. & other authors (2011). An elastase-dependent attenuated heterologous swine influenza virus protects against pandemic H1N1 2009 influenza challenge in swine. Vaccine 29, 3118-3123.
2. Bartha, A. (1961). Experimental reduction of virulence of Aujeszky's disease virus. Magy Állatorv Lapja 16, 42-45.
3. Dorsch-Hasler, K., Keil, G. M., Weber, F., Jasin, M., Schaffner, W. & Koszinowski, U. H. (1985). A long and complex enhancer activates transcription of the gene coding for the highly abundant immediate early mRNA in murine cytomegalovirus. Proc Natl Acad Sci U S A 82, 8325-8329.
4. Fuchs, W., Klupp, B. G., Granzow, H., Hengartner, C., Brack, A., Mundt, A., Enquist, L. W. & Mettenleiter, T. C. (2002). Physical interaction between envelope glycoproteins E and M of pseudorabies virus and the major tegument protein UL49. J Virol 76, 8208-8217.
5. Fuchs, W., Backovic, M., Klupp, B. G., Rey, F. A. & Mettenleiter, T. C. (2012). Structure-based mutational analysis of the highly conserved domain IV of glycoprotein H of pseudorabies virus. J Virol 86, 8002-8013.
6. Furuse, Y., Shimabukuro, K., Odagiri, T., Sawayama, R., Okada, T., Khandaker, I., Suzuki, A. & Oshitani, H. (2010). Comparison of selection pressures on the HA gene of pandemic (2009) and seasonal human and swine influenza A H1 subtype viruses. Virology 405, 314-321.
7. Garten, R. J., Davis, C. T., Russell, C. A., Shu, B., Lindstrom, S., Balish, A., Sessions, W. M., Xu, X., Skepner, E. & other authors (2009). Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science 325, 197-201.
8. Gorres, J. P., Lager, K. M., Kong, W. P., Royals, M., Todd, J. P., Vincent, A. L., Wei, C. J., Loving, C. L., Zanella, E. L. & other authors (2011). DNA vaccination elicits protective immune responses against pandemic and classic swine influenza viruses in pigs. Clin Vaccine Immunol 18, 1987-1995.
9. Hoffmann, B., Harder, T., Lange, E., Kalthoff, D., Reimann, I., Grund, C., Oehme, R., Vahlenkamp, T. W. & Beer, M. (2010). New real-time reverse transcriptase polymerase chain reactions facilitate detection and differentiation of novel A/H1N1 influenza virus in porcine and human samples. Berl Munch Tierarztl Wochenschr 123, 286-292.
10. Jiang, Y., Fang, L., Xiao, S., Zhang, H., Pan, Y., Luo, R., Li, B. & Chen, H. (2007). Immunogenicity and protective efficacy of recombinant pseudorabies virus expressing the two major membrane-associated proteins of porcine reproductive and respiratory syndrome virus. Vaccine 25, 547-560.
11. King, A. M. Q., Adams, M. J., Carstens, E. B. & Lefkowitz, E., J. (editors) (2012). Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses. San Diego: Elsevier Academic Press.
12. Klupp, B. G., Granzow, H. & Mettenleiter, T. C. (2000). Primary envelopment of pseudorabies virus at the nuclear membrane requires the UL34 gene product. J Virol 74, 10063-10073.
13. Klupp, B. G., Hengartner, C. J., Mettenleiter, T. C. & Enquist, L. W. (2004). Complete, annotated sequence of the pseudorabies virus genome. J Virol 78, 424-440.
14. Kopp, M., Granzow, H., Fuchs, W., Klupp, B. G., Mundt, E., Karger, A. & Mettenleiter, T. C. (2003). The pseudorabies virus UL11 protein is a virion component involved in secondary envelopment in the cytoplasm. J Virol 77, 5339-5351.
15. Lange, E., Kalthoff, D., Blohm, U., Teifke, J. P., Breithaupt, A., Maresch, C., Starick, E., Fereidouni, S., Hoffmann, B. & other authors (2009). Pathogenesis and transmission of the novel swine-origin influenza virus A/H1N1 after experimental infection of pigs. J Gen Virol 90, 2119-2123.
16. Le Hir, H., Nott, A. & Moore, M. J. (2003). How introns influence and enhance eukaryotic gene expression. Trends Biochem Sci 28, 215-220.
17. Li, Y., Reddy, K., Reid, S. M., Cox, W. J., Brown, I. H., Britton, P., Nair, V. & Iqbal, M. (2011). Recombinant herpesvirus of turkeys as a vector-based vaccine against highly pathogenic H7N1 avian influenza and Marek's disease. Vaccine 29, 8257-8266.
18. Lomniczi, B., Watanabe, S., Ben-Porat, T. & Kaplan, A. S. (1987). Genome location and identification of functions defective in the Bartha vaccine strain of pseudorabies virus. J Virol 61, 796-801.
19. Ma, W. & Richt, J. A. (2010). Swine influenza vaccines: current status and future perspectives. Anim Health Res Rev 11, 81-96.
20. Mettenleiter, T. C. (1989). Glycoprotein gIII deletion mutants of pseudorabies virus are impaired in virus entry. Virology 171, 623-625.
21. Mettenleiter, T. C. (2000). Aujeszky's disease (pseudorabies) virus: the virus and molecular pathogenesis state of the art, June 1999. Vet Res 31, 99-115.
22. Mettenleiter, T. C. (2002). Herpesvirus assembly and egress. J Virol 76, 1537-1547.
23. Muller, T., Hahn, E. C., Tottewitz, F., Kramer, M., Klupp, B. G., Mettenleiter, T. C. & Freuling, C. (2011). Pseudorabies virus in wild swine: a global perspective. Arch Virol 156, 1691-1705.
24. O'Connor, M., Peifer, M. & Bender, W. (1989). Construction of large DNA segments in Escherichia coli. Science 244, 1307-1312.
25. Palese, P. & Shaw, M. L. (2007). Orthomyxoviridae: the viruses and their replication. In Fields virology, 5th edn, pp. 1647-1689. Edited by D. M. Knipe & P. M. Howley. Philadelphia, PA: Lippincott Williams & Wilkins.
26. Pavlova, S. P., Veits, J., Keil, G. M., Mettenleiter, T. C. & Fuchs, W. (2009). Protection of chickens against H5N1 highly pathogenic avian influenza virus infection by live vaccination with infectious laryngotracheitis virus recombinants expressing H5 hemagglutinin and N1 neuraminidase. Vaccine 27, 773-785.
27. Pena, L., Vincent, A. L., Ye, J., Ciacci-Zanella, J. R., Angel, M., Lorusso, A., Gauger, P. C., Janke, B. H., Loving, C. L. & Perez, D. R. (2011). Modifications in the polymerase genes of a swine-like triple-reassortant influenza virus to generate live attenuated vaccines against 2009 pandemic H1N1 viruses. J Virol 85, 456-469.
28. Pomeranz, L. E., Reynolds, A. E. & Hengartner, C. J. (2005). Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine. Microbiol Mol Biol Rev 69, 462-500.
29. Qian, P., Li, X. M., Jin, M. L., Peng, G. Q. & Chen, H. C. (2004). An approach to a FMD vaccine based on genetic engineered attenuated pseudorabies virus: one experiment using VP1 gene alone generates an antibody responds on FMD and pseudorabies in swine. Vaccine 22, 2129-2136.
30. Reed, L. J. & Muench, H. (1938). A simple method of estimating fifty percent endpoints. Am J Hyg 27, 493-497.
31. Said, A., Damiani, A., Ma, G., Kalthoff, D., Beer, M. & Osterrieder, N. (2011). An equine herpesvirus 1 (EHV-1) vectored H1 vaccine protects against challenge with swine-origin influenza virus H1N1. Vet Microbiol 154, 113-123.
32. Said, A., Lange, E., Beer, M., Damiani, A. & Osterrieder, N. (2013). Recombinant equine herpesvirus 1 (EHV-1) vaccine protects pigs against challenge with influenza A(H1N1)pmd09. Virus Res 173, 371-376.
33. Sedegah, M., Chiang, C. H., Weiss, W. R., Mellouk, S., Cochran, M. D., Houghten, R. A., Beaudoin, R. L., Smith, D. & Hoffman, S. L. (1992). Recombinant pseudorabies virus carrying a plasmodium gene: herpesvirus as a new live viral vector for inducing T-and B-cell immunity. Vaccine 10, 578-584.
34. Shu, M., Taddeo, B., Zhang, W. & Roizman, B. (2013). Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein. Proc Natl Acad Sci U S A 110, E1669-E1675.
35. Smith, G. J., Vijaykrishna, D., Bahl, J., Lycett, S. J., Worobey, M., Pybus, O. G., Ma, S. K., Cheung, C. L., Raghwani, J. & other authors (2009). Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature 459, 1122-1125.
36. Szpara, M. L., Tafuri, Y. R., Parsons, L., Shamim, S. R., Verstrepen, K. J., Legendre, M. & Enquist, L. W. (2011). A wide extent of inter-strain diversity in virulent and vaccine strains of alphaherpesviruses. PLoS Pathog 7, e1002282.
37. Taylor, J., Weinberg, R., Kawaoka, Y., Webster, R. G. & Paoletti, E. (1988). Protective immunity against avian influenza induced by a fowlpox virus recombinant. Vaccine 6, 504-508.
38. Tenbusch, M., Grunwald, T., Niezold, T., Storcksdieck Genannt Bonsmann, M., Hannaman, D., Norley, S. & Uberla, K. (2010). Codon-optimization of the hemagglutinin gene from the novel swine origin H1N1 influenza virus has differential effects on CD4(+) T-cell responses and immune effector mechanisms following DNA electro-poration in mice. Vaccine 28, 3273-3277.
39. Thomsen, D. R., Marchioli, C. C., Yancey, R. J., Jr & Post, L. E. (1987a). Replication and virulence of pseudorabies virus mutants lacking glycoprotein gX. J Virol 61, 229-232.
40. Thomsen, D. R., Marotti, K. R., Palermo, D. P. & Post, L. E. (1987b). Pseudorabies virus as a live virus vector for expression of foreign genes. Gene 57, 261-265.
41. Tian, Z. J., Zhou, G. H., Zheng, B. L., Qiu, H. J., Ni, J. Q., Yang, H. L., Yin, X. N., Hu, S. P. & Tong, G. Z. (2006). A recombinant pseudorabies virus encoding the HA gene from H3N2 subtype swine influenza virus protects mice from virulent challenge. Vet Immunol Immunopathol 111, 211-218.
42. van Oirschot, J. T. (1999). Diva vaccines that reduce virus transmission. J Biotechnol 73, 195-205.
43. Van Reeth, K. (2007). Avian and swine influenza viruses: our current understanding of the zoonotic risk. Vet Res 38, 243-260.
44. van Zijl, M., Wensvoort, G., de Kluyver, E., Hulst, M., van der Gulden, H., Gielkens, A., Berns, A. & Moormann, R. (1991). Live attenuated pseudorabies virus expressing envelope glycoprotein E1 of hog cholera virus protects swine against both pseudorabies and hog cholera. J Virol 65, 2761-2765.
45. Veits, J., Wiesner, D., Fuchs, W., Hoffmann, B., Granzow, H., Starick, E., Mundt, E., Schirrmeier, H., Mebatsion, T. & other authors (2006). Newcastle disease virus expressing H5 hemagglutinin gene protects chickens against Newcastle disease and avian influenza. Proc Natl Acad Sci U S A 103, 8197-8202.
46. Vincent, A. L., Ciacci-Zanella, J. R., Lorusso, A., Gauger, P. C., Zanella, E. L., Kehrli, M. E., Jr, Janke, B. H. & Lager, K. M. (2010). Efficacy of inactivated swine influenza virus vaccines against the 2009 A/H1N1 influenza virus in pigs. Vaccine 28, 2782-2787.
47. Vincent, A. L., Ma, W., Lager, K. M., Richt, J. A., Janke, B. H., Sandbulte, M. R., Gauger, P. C., Loving, C. L., Webby, R. J. & García-Sastre, A. (2012). Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccine-associated enhanced respiratory disease. J Virol 86, 10597-10605.
48. Webster, R. G., Wright, S. M., Castrucci, M. R., Bean, W. J. & Kawaoka, Y. (1993). Influenza a model of an emerging virus disease. Intervirology 35, 16-25.
49. Wei, F., Zhai, Y., Jin, H., Shang, L., Men, J., Lin, J., Fu, Z., Shi, Y., Zhu, X. Q. & other authors (2010). Development and immunogenicity of a recombinant pseudorabies virus expressing Sj26GST and SjFABP from Schistosoma japonicum. Vaccine 28, 5161-5166.
50. Whealy, M. E., Robbins, A. K. & Enquist, L. W. (1990). The export pathway of the pseudorabies virus gB homolog gII involves oligomer formation in the endoplasmic reticulum and protease processing in the Golgi apparatus. J Virol 64, 1946-1955.