Elucidation of final steps of the marineosins biosynthetic pathway through identification and characterization of the corresponding gene cluster

Journal of the American Chemical Society

Volumn 136, Issue 12, 2014, Pages 4565-4574

  Salem, Shaimaa M ^a   Kancharla, Papireddy ^a   Florova, Galina ^a   Gupta, Shweta ^a   Lu, Wanli ^a   Reynolds, Kevin A ^a  

^a PORTLAND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYSIS; CYCLIZATION; GENES;

BIOLOGICALLY ACTIVE MOLECULES; BIOSYNTHETIC GENE CLUSTER; BIOSYNTHETIC PATHWAY; GENE CLUSTERS; GENE ORGANIZATION; HETEROLOGOUS EXPRESSION; HYDROXYL FUNCTIONALITY; MARINE STREPTOMYCES;

BIOSYNTHESIS;

ISOMERASE; MARINEOSIN A; MARINEOSIN B; PYRROLE; UNCLASSIFIED DRUG; ANTIMALARIAL AGENT; PRODIGININE; PRODIGIOSIN; PYRROLE DERIVATIVE; SPIRO COMPOUND;

ARTICLE; BACTERIAL STRAIN; BIOSYNTHESIS; CYCLIZATION; DIASTEREOISOMER; ENZYME STRUCTURE; GENE CLUSTER; HETEROLOGOUS EXPRESSION; NONHUMAN; PLASMID; STREPTOMYCES; ANALOGS AND DERIVATIVES; DRUG EFFECTS; GENETICS; METABOLISM; MOLECULAR CLONING; MULTIDRUG RESISTANCE; MULTIGENE FAMILY; OXIDATION REDUCTION REACTION; PLASMODIUM FALCIPARUM; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

ANTIMALARIALS; CLONING, MOLECULAR; DRUG RESISTANCE, MULTIPLE; MULTIGENE FAMILY; OXIDATION-REDUCTION; PLASMODIUM FALCIPARUM; PRODIGIOSIN; PYRROLES; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPIRO COMPOUNDS; STREPTOMYCES;

EID: 84897069952     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja411544w     Document Type: Article

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