Role and substrate specificity of the Streptomyces coelicolor RedH enzyme in undecylprodiginine biosynthesis

Chemical Communications

Volumn , Issue 16, 2008, Pages 1865-1867

  Haynes, Stuart W ^a   Sydor, Paulina K ^a   Stanley, Anna E ^a   Song, Lijiang ^a   Challis, Gregory L ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 UNDECYLPYRROLE; 4 METHOXY 2,2' BIPYRROLE 5 CARBOXALDEHYDE; ALDEHYDE; MICROBIAL ENZYME; NATURAL PRODUCT; PYRROLE DERIVATIVE; REDH ENZYME; STREPTORUBIN B; UNCLASSIFIED DRUG; UNDECYLPRODIGININE;

ARTICLE; CATALYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME SPECIFICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; POLYMERIZATION; STREPTOMYCES COELICOLOR; SUZUKI REACTION; ULTRAVIOLET SPECTROSCOPY;

EID: 41849109815     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b801677a     Document Type: Article

References (19)

1. A. Mortellaro S. Songia P. Gnocchi M. Ferrari C. Fornasiero R. D'Alessio A. Isetta F. Colotta J. Golay J. Immunol. 1999 162 7102 7109
2. N. N. Gerber J. Antibiot. 1975 28 194 199
3. M. Isaka A. Jaturapat J. Kramyu M. Tanticharoen Y. Thebtaranonth Antimicrob. Agents Chemother. 2002 46 1112 1113
4. B. Montaner R. Perez-Tomas Curr. Cancer Drug Targets 2003 3 57 65
5. A. Fürtsner Angew. Chem., Int. Ed. 2003 42 3582 3603
6. G. C. Shore, J. Bajorath, F. L. Stahura and M. S. R. Murthy, International patent application WO 2003015788, 2003
7. M. Nguyen R. C. Marcellus A. Roulston M. Watson L. Serfass S. R. M. Madiraju D. Goulet J. Viallet L. Belec X. Billot S. Acoca E. Purisima A. Wiegmans L. Cluse R. W. Johnstone P. Beauparlant G. C. Shore Proc. Natl. Acad. Sci. U. S. A. 2007 104 19512 19517
8. S. W. Tsao B. A. Rudd X. G. He C. J. Chang H. G. Floss J. Antibiot. 1985 38 128 131
9. S. J. Mo P. K. Sydor C. Corre M. M. Alhamadsheh A. E. Stanley S. W. Haynes L. Song K. A. Reynolds G. L. Challis Chem. Biol. 2008 15 137 148
10. A. M. Cerdeno M. J. Bibb G. L. Challis Chem. Biol. 2001 8 211 224
11. A. E. Stanley L. J. Walton M. Kourdi-Zerikly C. Corre G. L. Challis Chem. Commun. 2006 3981 3983
12. M. G. Thomas M. D. Burkart C. T. Walsh Chem. Biol. 2002 9 171 184
13. S. Garneau-Tsodikova P. C. Dorrestein N. L. Kelleher C. T. Walsh J. Am. Chem. Soc. 2006 128 12600 12601
14. N. R. Williamson H. T. Simonsen R. A. A. Ahmed G. Goldet H. Slater L. Woodley F. J. Leeper G. P. C. Salmond Mol. Microbiol. 2005 56 971 989
15. B. Gust G. L. Challis K. Fowler T. Kieser K. F. Chater Proc. Natl. Acad. Sci. U. S. A. 2003 100 1541 1546
16. K. Dairi S. Tripathy G. Attardo J.-F. Lavallée Tetrahedron Lett. 2006 47 2605 2606
17. Y. Kayakawa K. Kawakami H. Seto K. Furihata Tetrahedron Lett. 1992 33 2701 2704
18. H. H. Wasserman G. C. Rodgers D. D. Keith Tetrahedron 1976 32 1851 1854
19. These results were first presented on 20 June 2007 at the Chemistry and Biology of Natural Products Biosynthesis III, University of Bristol, UK