Pharmacologically antagonizing the CXCR4-CXCL12 chemokine pathway with AMD3100 inhibits sunlight-induced skin cancer

Journal of Investigative Dermatology

Volumn 134, Issue 4, 2014, Pages 1091-1100

  Sarchio, Seri N E ^a,b,c   Scolyer, Richard A ^a,b,d   Beaugie, Clare ^a,b   McDonald, David ^a,b,e   Marsh Wakefield, Felix ^a,b   Halliday, Gary M ^a,b   Byrne, Scott N ^a,b,f  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^c UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^d MELANOMA INSTITUTE AUSTRALIA   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

^f UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CYTOKERATIN; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER PREVENTION; CELL MIGRATION; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; FEMALE; HISTOPATHOLOGY; IMMUNOSUPPRESSIVE TREATMENT; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN CANCER; SKIN CARCINOMA; SKIN FIBROBLAST; SUNLIGHT; TUMOR IMMUNITY; ULTRAVIOLET RADIATION; UPREGULATION;

ANIMALS; BONE MARROW CELLS; CARCINOMA, SQUAMOUS CELL; CELL MOVEMENT; CHEMOKINE CXCL12; FEMALE; FLUORESCEINS; GENE EXPRESSION REGULATION; HETEROCYCLIC COMPOUNDS; IMMUNE SYSTEM; LYMPH NODES; MAST CELLS; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; NEOPLASMS, RADIATION-INDUCED; RECEPTORS, CXCR4; SKIN NEOPLASMS; SUCCINIMIDES; SUNLIGHT; ULTRAVIOLET RAYS;

EID: 84897043008     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2013.424     Document Type: Article

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