D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB

Asian Pacific Journal of Cancer Prevention

Volumn 15, Issue 4, 2014, Pages 1757-1762

  Rengarajan, Thamaraiselvan ^a,b   Nandakumar, Natarajan ^a,c   Rajendran, Peramaiyan ^b   Haribabu, Lingaiah ^a   Nishigaki, Ikuo ^b   Balasubramanian, Maruthaiveeran Periyasamy ^a  

^a UNIVERSITY OF MADRAS   (India)

^b NPO International Laboratory of Biochemistry   (Japan)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Apoptosis; Breast cancer; D pinitol; MCF 7; MTT assay

Indexed keywords

ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; GLUTATHIONE; INOSITOL; LACTATE DEHYDROGENASE; PINITOL; PLANT MEDICINAL PRODUCT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; TRANSCRIPTION FACTOR RELA;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; BREAST TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DNA FRAGMENTATION; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; HUMAN; MCF 7 CELL LINE; METABOLISM; PATHOLOGY; SECRETION (PROCESS); SOYBEAN; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DNA FRAGMENTATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE; HUMANS; INOSITOL; L-LACTATE DEHYDROGENASE; MCF-7 CELLS; PLANT PREPARATIONS; PROTO-ONCOGENE PROTEINS C-BCL-2; SOYBEANS; TRANSCRIPTION FACTOR RELA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84896975951     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.4.1757     Document Type: Article

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