Telomere recombination preferentially occurs at short telomeres in telomerase-null type II survivors

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Fu, Xiao Hong ^a   Duan, Yi Min ^a   Liu, Yu Ting ^a   Cai, Chen ^b   Meng, Fei Long ^a   Zhou, Jin Qiu ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^b SHANGHAITECH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEIC ACID BINDING PROTEIN; PROTEIN RAD59; RAD50 PROTEIN; TELOMERASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL DIVISION; CELL JUNCTION; CHROMOSOME SIZE; COMPLEX FORMATION; CONTROLLED STUDY; GENETIC RECOMBINATION; NONHUMAN; NULL CELL; PROTEIN FUNCTION; RECOMBINATION REPAIR; SACCHAROMYCES CEREVISIAE; SENESCENCE; SEQUENCE ANALYSIS; TELOMERE; TELOMERE RECOMBINATION;

AGING; BASE SEQUENCE; BLOTTING, SOUTHERN; DNA-BINDING PROTEINS; GENE KNOCKOUT TECHNIQUES; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, DNA; TELOMERASE; TELOMERE;

EID: 84896943772     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090644     Document Type: Article

References (40)

1. Greider CW (1996) Telomere length regulation. Annu Rev Biochem 65: 337-365.
2. Zakian VA (1996) Structure, function, and replication of Saccharomyces cerevisiae telomeres. Annu Rev Genet 30: 141-172.
3. Wellinger RJ, Wolf AJ, Zakian VA (1993) Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase. Cell 72: 51-60. (Pubitemid 23029692)
4. Chan CS, Tye BK (1983) Organization of DNA sequences and replication origins at yeast telomeres. Cell 33: 563-573. (Pubitemid 13062502)
5. Zakian VA, Blanton HM (1988) Distribution of telomere-associated sequences on natural chromosomes in Saccharomyces cerevisiae. Mol Cell Biol 8: 2257-2260.
6. Greider CW, Blackburn EH (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43: 405-413. (Pubitemid 16213265)
7. Nugent CI, Lundblad V (1998) The telomerase reverse transcriptase: components and regulation. Genes Dev 12: 1073-1085. (Pubitemid 28194043)
8. Hughes TR, Evans SK, Weilbaecher RG, Lundblad V (2000) The Est3 protein is a subunit of yeast telomerase. Curr Biol 10: 809-812. (Pubitemid 30466947)
9. Lundblad V, Szostak JW (1989) A mutant with a defect in telomere elongation leads to senescence in yeast. Cell 57: 633-643.
10. Singer MS, Gottschling DE (1994) TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 266: 404-409. (Pubitemid 24348957)
11. Steiner BR, Hidaka K, Futcher B (1996) Association of the Est1 protein with telomerase activity in yeast. Proc Natl Acad Sci U S A 93: 2817-2821. (Pubitemid 26116238)
12. Counter CM, Meyerson M, Eaton EN, Weinberg RA (1997) The catalytic subunit of yeast telomerase. Proc Natl Acad Sci U S A 94: 9202-9207. (Pubitemid 27357807)
13. Lendvay TS, Morris DK, Sah J, Balasubramanian B, Lundblad V (1996) Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. Genetics 144: 1399-1412. (Pubitemid 26427890)
14. Lundblad V, Blackburn EH (1993) An alternative pathway for yeast telomere maintenance rescues est1- senescence. Cell 73: 347-360. (Pubitemid 23123312)
15. Teng SC, Zakian VA (1999) Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol Cell Biol 19: 8083-8093.
16. Le S, Moore JK, Haber JE, Greider CW (1999) RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics 152: 143-152.
17. Chen Q, Ijpma A, Greider CW (2001) Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events. Mol Cell Biol 21: 1819-1827. (Pubitemid 32156401)
18. Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR (1997) Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 3: 1271-1274. (Pubitemid 27508830)
19. Reddel RR, Bryan TM, Colgin LM, Perrem KT, Yeager TR (2001) Alternative lengthening of telomeres in human cells. Radiat Res 155: 194-200. (Pubitemid 33723538)
20. McEachern MJ, Haber JE (2006) Break-induced replication and recombinational telomere elongation in yeast. Annu Rev Biochem 75: 111-135. (Pubitemid 44118028)
21. Teng SC, Chang J, McCowan B, Zakian VA (2000) Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process. Mol Cell 6: 947-952.
22. Hu Y, Tang HB, Liu NN, Tong XJ, Dang W, et al. (2013) Telomerase-null survivor screening identifies novel telomere recombination regulators. PLoS Genet 9: e1003208.
23. Tsai YL, Tseng SF, Chang SH, Lin CC, Teng SC (2002) Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination. Mol Cell Biol 22: 5679-5687.
24. Straatman KR, Louis EJ (2007) Localization of telomeres and telomere-associated proteins in telomerase-negative Saccharomyces cerevisiae. Chromosome Res 15: 1033-1050.
25. Bianchi A, Shore D (2007) Early replication of short telomeres in budding yeast. Cell 128: 1051-1062. (Pubitemid 46437258)
26. Arneric M, Lingner J (2007) Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast. EMBO Rep 8: 1080-1085. (Pubitemid 350042345)
27. Sabourin M, Tuzon CT, Zakian VA (2007) Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol Cell 27: 550-561. (Pubitemid 47238635)
28. Hector RE, Shtofman RL, Ray A, Chen BR, Nyun T, et al. (2007) Tel1p preferentially associates with short telomeres to stimulate their elongation. Mol Cell 27: 851-858. (Pubitemid 47333228)
29. Chang M, Dittmar JC, Rothstein R (2011) Long telomeres are preferentially extended during recombination-mediated telomere maintenance. Nat Struct Mol Biol 18: 451-456.
30. Kozak ML, Chavez A, Dang W, Berger SL, Ashok A, et al. (2010) Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. EMBO J 29: 158-170.
31. Diede SJ, Gottschling DE (1999) Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell 99: 723-733. (Pubitemid 30017643)
32. Meng FL, Hu Y, Shen N, Tong XJ, Wang J, et al. (2009) Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication. EMBO J 28: 1466-1478.
33. Forstemann K, Hoss M, Lingner J (2000) Telomerase-dependent repeat divergence at the 3′ ends of yeast telomeres. Nucleic Acids Res 28: 2690-2694. (Pubitemid 30488012)
34. Natarajan S, McEachern MJ (2002) Recombinational telomere elongation promoted by DNA circles. Mol Cell Biol 22: 4512-4521. (Pubitemid 34620389)
35. Sikorski RS, Hieter P (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
36. Wellinger RJ (2010) When the caps fall off: responses to telomere uncapping in yeast. FEBS Lett 584: 3734-3740.
37. McEachern MJ, Iyer S (2001) Short telomeres in yeast are highly recombinogenic. Mol Cell 7: 695-704. (Pubitemid 32436431)
38. Topcu Z, Nickles K, Davis C, McEachern MJ (2005) Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis. Proc Natl Acad Sci U S A 102: 3348-3353. (Pubitemid 40328048)
39. IJpma AS, Greider CW (2003) Short Telomeres Induce a DNA Damage Response in Saccharomyces cerevisiae. Mol Biol Cell 14: 987-1001.
40. Sandell LL, Zakian VA (1993) Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell 75: 729-739. (Pubitemid 23346371)