Simvastatin inhibits glucose metabolism and legumain activity in human myotubes

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Smith, Robert ^a   Solberg, Rigmor ^a   Jacobsen, Linn Løkken ^a   Voreland, Anette Larsen ^a   Rustan, Arild Christian ^a   Thoresen, Hege ^a,b   Johansen, Harald Thidemann ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGLUCOSE; FARNESYL DIPHOSPHATE; GERANYLGERANYL PYROPHOSPHATE; GLUCOSE; LEGUMAIN; MEVALONOLACTONE; SIMVASTATIN;

ABDOMINAL INTERNAL OBLIQUE MUSCLE; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL MATURATION; CELL PROLIFERATION; CELL VIABILITY ASSAY; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISORDERS OF CARBOHYDRATE METABOLISM; DRUG MECHANISM; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; GLUCOSE OXIDATION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INCUBATION TIME; MUSCLE DISEASE; MYOTUBE; SKELETAL MUSCLE; SKELETAL MUSCLE SATELLITE CELL;

CATHEPSIN B; CATHEPSIN L; CELL MEMBRANE; CYSTEINE ENDOPEPTIDASES; GLUCOSE; HEK293 CELLS; HUMANS; MEVALONIC ACID; MUSCLE FIBERS, SKELETAL; OXIDATION-REDUCTION; OXIDATIVE PHOSPHORYLATION; POLYISOPRENYL PHOSPHATES; SESQUITERPENES; SIMVASTATIN;

EID: 84896940518     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085721     Document Type: Article

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