Naturally occurring mutations in the PA gene are key contributors to increased virulence of pandemic H1N1/09 influenza virus in mice

Journal of Virology

Volumn 88, Issue 8, 2014, Pages 4600-4604

  Sun, Yipeng ^a   Xu, Qi ^a,b   Shen, Ye ^a   Liu, Linqing ^a   Wei, Kai ^a   Sun, Honglei ^a   Pu, Juan ^a   Chang, Kin Chow ^c   Liu, Jinhua ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b China Animal Disease Control Center   (China)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RIBONUCLEOPROTEIN;

AMINO ACID ANALYSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; FEMALE; GENE MUTATION; HEALTH SURVEY; HISTOPATHOLOGY; HUMAN; INFLUENZA VIRUS A H1N1; LD 50; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PA GENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; VIRUS GENE; VIRUS REPLICATION; VIRUS VIRULENCE;

AMINO ACID SEQUENCE; ANIMALS; FEMALE; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTATION; NORTH AMERICA; ORTHOMYXOVIRIDAE INFECTIONS; PANDEMICS; RNA REPLICASE; SWINE; SWINE DISEASES; VIRAL PROTEINS; VIRULENCE;

EID: 84896936011     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03158-13     Document Type: Article

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