Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Lu, Jeng Wei ^a,b   Liao, Chung Yi ^a,e   Yang, Wan Yu ^a   Lin, Yueh Min ^c,d   Jin, Shiow Lian Catherine ^b   Wang, Horng Dar ^e   Yuh, Chiou Hwa ^a,e,f  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^c CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^d JEN TEH JUNIOR COLLEGE OF MEDICINE   (Taiwan)

^e NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^f NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ENDOTHELIN 1; FLUORESCENT DYE; GLYCOGEN; MCHERRY; MICRORNA 1; PROTEIN IRE1; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN PERK; RNA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT DILATATION; CANCER GROWTH; CANCER PATIENT; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; FATTY LIVER; GENE EXPRESSION REGULATION; GLYCOGEN METABOLISM; IN VITRO STUDY; LIVER CANCER; LIVER CARCINOGENESIS; LIVER FIBROSIS; LIVER HYPERPLASIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA SPLICING; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; TRANSGENIC ANIMAL; UNFOLDED PROTEIN RESPONSE; UPREGULATION; XENOTRANSPLANTATION; ZEBRA FISH;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; ENDOTHELIN-1; FATTY LIVER; GENE EXPRESSION; HEK293 CELLS; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MICRORNAS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; UNFOLDED PROTEIN RESPONSE; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84896916006     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085318     Document Type: Article

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