Peripheral administration of poly I: C leads to increased hippocampal amyloid-beta and cognitive deficits in a non-transgenic mouse

Behavioural Brain Research

Volumn 266, Issue , 2014, Pages 183-187

  Weintraub, Marielle K ^a   Kranjac, Dinko ^a   Eimerbrink, Micah J ^a   Pearson, Scott J ^a   Vinson, Ben T ^a   Patel, Jigna ^a   Summers, Whitney M ^a   Parnell, Thomas B ^a   Boehm, Gary W ^a   Chumley, Michael J ^a  

^a TEXAS CHRISTIAN UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Amyloid beta; Cognition; Cytokines; Poly I:C

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; DIMER; MONOMER; OLIGOMER; POLYINOSINIC POLYCYTIDYLIC ACID; SODIUM CHLORIDE; TETRAMER; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); CYTOKINE; INTERFERON INDUCING AGENT; PEPTIDE FRAGMENT;

AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN TISSUE; CELL COMMUNICATION; CHRONIC INFLAMMATION; COGNITIVE DEFECT; CONDITIONING; CONTROLLED STUDY; DISEASE COURSE; FEAR; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL NECROSIS; NEUROFIBRILLARY TANGLE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; CATALEPSY; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; PATHOLOGY; TIME; TOXICITY;

AMYLOID BETA-PEPTIDES; ANALYSIS OF VARIANCE; ANIMALS; COGNITION DISORDERS; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FREEZING REACTION, CATALEPTIC; HIPPOCAMPUS; INTERFERON INDUCERS; MALE; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; POLY I-C; TIME FACTORS;

EID: 84896915035     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2014.03.009     Document Type: Article

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