Lipopolysaccharide engineering in Neisseria meningitidis: Structural analysis of different pentaacyl lipid a mutants and comparison of their modified agonist properties

Journal of Biological Chemistry

Volumn 289, Issue 12, 2014, Pages 8668-8680

  Pupo, Elder ^a   Hamstra, Hendrik Jan ^b   Meiring, Hugo ^a   Van Der Ley, Peter ^a  

^a Institute for Translational Vaccinology   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CELL CULTURE; GENE ENCODING; GLYCOPROTEINS; MASS SPECTROMETRY; OLIGOSACCHARIDES;

BIOSYNTHETIC PATHWAY; COMPOSITIONAL ANALYSIS; GALACTOSE RESIDUES; GALACTOSYLTRANSFERASE; LIPOPOLYSACCHARIDES; MASS SPECTROMETRY ANALYSIS; NEISSERIA MENINGITIDIS; STRUCTURE-FUNCTION ANALYSIS;

GENE EXPRESSION;

BACTERIAL ENZYME; BACTERIUM LIPOPOLYSACCHARIDE; GALACTOSYLTRANSFERASE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 6; LIPID A 3 O DEACYLASE; OLIGOSACCHARIDE GALACTOSYLTRANSFERASE; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BIOENGINEERING; BORDETELLA BRONCHISEPTICA; CARBOHYDRATE SYNTHESIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE FUNCTION; GENE IDENTIFICATION; GENE INACTIVATION; IMMUNOMODULATION; LGTB GENE; MASS SPECTROMETRY; MOLECULAR DYNAMICS; NEISSERIA MENINGITIDIS; NONHUMAN; PAGL GENE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN STRUCTURE; QUALITATIVE ANALYSIS; RESIDUE ANALYSIS; SPECIES COMPOSITION;

ADJUVANT; BIOTECHNOLOGY; CARBOHYDRATE BIOSYNTHESIS; GLYCOLIPIDS; HUMAN MONOCYTE; LIPOPOLYSACCHARIDE (LPS); LPXL1, PAGL; MASS SPECTROMETRY (MS); NEISSERIA MENINGITIDIS;

BORDETELLA; CARBOHYDRATE SEQUENCE; CELL LINE; CYTOKINES; GENES, BACTERIAL; GENETIC ENGINEERING; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOLOGIC FACTORS; LIPID A; MENINGITIS, MENINGOCOCCAL; MOLECULAR SEQUENCE DATA; MONOCYTES; MUTATION; NEISSERIA MENINGITIDIS;

EID: 84896912961     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.554345     Document Type: Article

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