Glycan-based DC-SIGN targeting vaccines to enhance antigen cross-presentation

Molecular Immunology

Volumn 55, Issue 2, 2013, Pages 143-145

  van Kooyk, Yvette ^a   Unger, Wendy W J ^a   Fehres, Cynthia M ^a   Kalay, Hakan ^a   García Vallejo, Juan J ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cell surface molecules; DC SIGN; Dendritic cells; Glycans; Human; Rodent; Skin

Indexed keywords

GLYCAN; LECTIN; LECTIN RECEPTOR; MONOCLONAL ANTIBODY; VACCINE;

ANTIGEN SPECIFICITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONJUGATION; CROSS PRESENTATION; CYTOKINE RESPONSE; DERMIS; HUMAN; IMMUNE RESPONSE; IN VIVO STUDY; LIGAND BINDING; MUCOSA; MYELOID DENDRITIC CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VACCINATION;

ANIMALS; ANTIGEN PRESENTATION; CD8-POSITIVE T-LYMPHOCYTES; CELL ADHESION MOLECULES; CROSS-PRIMING; DENDRITIC CELLS; HUMANS; LECTINS, C-TYPE; MICE; POLYSACCHARIDES; RECEPTORS, CELL SURFACE; RECEPTORS, PATTERN RECOGNITION; VACCINES;

RODENTIA;

EID: 84875633828     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.10.031     Document Type: Review

References (5)

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3. Schaefer M., Reiling N., Fessler C., et al. Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infection. Journal of Immunology 2008, 180(10):6836-6845.
4. Singh S.K., Stephani J., Schaefer M., et al. Targeting glycan modified OVA to murine DC-SIGN transgenic dendritic cells enhances MHC class I and II presentation. Molecular Immunology 2009, 47(2-3):164-174.
5. + T-cell responses by targeting DC-SIGN on dendritic cells. Journal of Controlled Release 2012, 160(1):88-95.