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Volumn 8, Issue MAR, 2014, Pages

Nociception and pain: Lessons from optogenetics

Author keywords

Amygdala; Nociception; Nociceptor; Pain; Prefrontal cortex; Spinal cord

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MU OPIATE RECEPTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1;

EID: 84896905138     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnbeh.2014.00069     Document Type: Review
Times cited : (44)

References (39)
  • 1
    • 48749123103 scopus 로고    scopus 로고
    • The cell and molecular basis of mechanical, cold, and inflammatory pain
    • doi: 10.1126/science.1156916
    • Abrahamsen, B., Zhao, J., Asante, C. O., Cendan, C. M., Marsh, S., Martinez-Barbera, J. P., et al. (2008). The cell and molecular basis of mechanical, cold, and inflammatory pain. Science 321, 702-705. doi: 10.1126/science.1156916
    • (2008) Science , vol.321 , pp. 702-705
    • Abrahamsen, B.1    Zhao, J.2    Asante, C.O.3    Cendan, C.M.4    Marsh, S.5    Martinez-Barbera, J.P.6
  • 2
    • 20644472635 scopus 로고    scopus 로고
    • Human brain mechanisms of pain perception and regulation in health and disease
    • doi: 10.1016/j.ejpain.2004.11.001
    • Apkarian, A. V., Bushnell, M. C., Treede, R.-D., and Zubieta, J.-K. (2005). Human brain mechanisms of pain perception and regulation in health and disease. Eur. J. Pain 9, 463-484. doi: 10.1016/j.ejpain.2004.11.001
    • (2005) Eur. J. Pain , vol.9 , pp. 463-484
    • Apkarian, A.V.1    Bushnell, M.C.2    Treede, R.-D.3    Zubieta, J.-K.4
  • 3
    • 84885134433 scopus 로고    scopus 로고
    • Parceling human accumbens into putative core and shell dissociates encoding of values for reward and pain
    • doi: 10.1523/jneurosci.1731-13.2013
    • Baliki, M. N., Mansour, A., Baria, A. T., Huang, L., Berger, S. E., Fields, H. L., et al. (2013). Parceling human accumbens into putative core and shell dissociates encoding of values for reward and pain. J. Neurosci. 33, 16383-16393. doi: 10.1523/jneurosci.1731-13.2013
    • (2013) J. Neurosci. , vol.33 , pp. 16383-16393
    • Baliki, M.N.1    Mansour, A.2    Baria, A.T.3    Huang, L.4    Berger, S.E.5    Fields, H.L.6
  • 4
    • 84875325415 scopus 로고    scopus 로고
    • Design and functional evaluation of an optically active μ-opioid receptor
    • doi: 10.1016/j.ejphar.2013.01.065
    • Barish, P. A., Xu, Y., Li, J., Sun, J., Jarajapu, Y. P. R., and Ogle, W. O. (2013). Design and functional evaluation of an optically active μ-opioid receptor. Eur. J. Pharmacol. 705, 42-48. doi: 10.1016/j.ejphar.2013.01.065
    • (2013) Eur. J. Pharmacol. , vol.705 , pp. 42-48
    • Barish, P.A.1    Xu, Y.2    Li, J.3    Sun, J.4    Jarajapu, Y.P.R.5    Ogle, W.O.6
  • 5
    • 33645231857 scopus 로고    scopus 로고
    • Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment
    • doi: 10.1016/j.ejpain.2005.06.009
    • Breivik, H., Collett, B., Ventafridda, V., Cohen, R., and Gallacher, D. (2006). Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur. J. Pain 10, 287-333. doi: 10.1016/j.ejpain.2005.06.009
    • (2006) Eur. J. Pain , vol.10 , pp. 287-333
    • Breivik, H.1    Collett, B.2    Ventafridda, V.3    Cohen, R.4    Gallacher, D.5
  • 6
    • 84879419333 scopus 로고    scopus 로고
    • Cognitive and emotional control of pain and its disruption in chronic pain
    • doi: 10.1038/nrn3516
    • Bushnell, M. C., Čeko, M., and Low, L. A. (2013). Cognitive and emotional control of pain and its disruption in chronic pain. Nat. Rev. Neurosci. 14, 502-511. doi: 10.1038/nrn3516
    • (2013) Nat. Rev. Neurosci. , vol.14 , pp. 502-511
    • Bushnell, M.C.1    Čeko, M.2    Low, L.A.3
  • 7
    • 66749156637 scopus 로고    scopus 로고
    • Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli
    • doi: 10.1073/pnas.0906213106
    • Cavanaugh, D. J., Lee, H., Lo, L., Shields, S. D., Zylka, M. J., Basbaum, A. I., et al. (2009). Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proc. Natl. Acad. Sci. U S A 106, 9075-9080. doi: 10.1073/pnas.0906213106
    • (2009) Proc. Natl. Acad. Sci. U S A , vol.106 , pp. 9075-9080
    • Cavanaugh, D.J.1    Lee, H.2    Lo, L.3    Shields, S.D.4    Zylka, M.J.5    Basbaum, A.I.6
  • 8
    • 84867247538 scopus 로고    scopus 로고
    • Central amygdala metabotropic glutamate receptor 5 in the modulation of visceral pain
    • doi: 10.1523/jneurosci.1473-12.2012
    • Crock, L. W., Kolber, B. J., Morgan, C. D., Sadler, K. E., Vogt, S. K., Bruchas, M. R., et al. (2012). Central amygdala metabotropic glutamate receptor 5 in the modulation of visceral pain. J. Neurosci. 32, 14217-14226. doi: 10.1523/jneurosci.1473-12.2012
    • (2012) J. Neurosci. , vol.32 , pp. 14217-14226
    • Crock, L.W.1    Kolber, B.J.2    Morgan, C.D.3    Sadler, K.E.4    Vogt, S.K.5    Bruchas, M.R.6
  • 9
    • 84893782140 scopus 로고    scopus 로고
    • Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward
    • doi: 10.1038/nn.3622
    • Cui, Y., Ostlund, S. B., James, A. S., Park, C. S., Ge, W., Roberts, K. W., et al. (2014). Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward. Nat. Neurosci. 17, 254-261. doi: 10.1038/nn.3622
    • (2014) Nat. Neurosci. , vol.17 , pp. 254-261
    • Cui, Y.1    Ostlund, S.B.2    James, A.S.3    Park, C.S.4    Ge, W.5    Roberts, K.W.6
  • 10
    • 84887842191 scopus 로고    scopus 로고
    • Remote optogenetic activation and sensitization of pain pathways in freely moving mice
    • doi: 10.1523/jneurosci.2424-13.2013
    • Daou, I., Tuttle, A. H., Longo, G., Wieskopf, J. S., Bonin, R. P., Ase, A. R., et al. (2013). Remote optogenetic activation and sensitization of pain pathways in freely moving mice. J. Neurosci. 33, 18631-18640. doi: 10.1523/jneurosci.2424-13.2013
    • (2013) J. Neurosci. , vol.33 , pp. 18631-18640
    • Daou, I.1    Tuttle, A.H.2    Longo, G.3    Wieskopf, J.S.4    Bonin, R.P.5    Ase, A.R.6
  • 11
    • 84888042461 scopus 로고    scopus 로고
    • Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons
    • doi: 10.1016/j.neuron.2013.08.015
    • Dougherty, K. J., Zagoraiou, L., Satoh, D., Rozani, I., Doobar, S., Arber, S., et al. (2013). Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons. Neuron 80, 920-933. doi: 10.1016/j.neuron.2013.08.015
    • (2013) Neuron , vol.80 , pp. 920-933
    • Dougherty, K.J.1    Zagoraiou, L.2    Satoh, D.3    Rozani, I.4    Doobar, S.5    Arber, S.6
  • 12
    • 84902547298 scopus 로고    scopus 로고
    • Nucleus accumbens specific interventions in RGS9-2 activity modulate responses to morphine
    • doi: 10.1038/npp.2014.45. [Epub ahead of print]
    • Gaspari, S., Papachatzaki, M. M., Koo, J. W., Carr, F. B., Tsimpanouli, M. E., Stergiou, E., et al. (2014). Nucleus accumbens specific interventions in RGS9-2 activity modulate responses to morphine. Neuropsychopharmacology doi: 10.1038/npp.2014.45. [Epub ahead of print].
    • (2014) Neuropsychopharmacology
    • Gaspari, S.1    Papachatzaki, M.M.2    Koo, J.W.3    Carr, F.B.4    Tsimpanouli, M.E.5    Stergiou, E.6
  • 13
    • 0036199626 scopus 로고    scopus 로고
    • Pain pathways and parabrachial circuits in the rat
    • doi: 10.1113/eph8702357
    • Gauriau, C., and Bernard, J.-F. (2002). Pain pathways and parabrachial circuits in the rat. Exp. Physiol. 87, 251-258. doi: 10.1113/eph8702357
    • (2002) Exp. Physiol. , vol.87 , pp. 251-258
    • Gauriau, C.1    Bernard, J.-F.2
  • 14
    • 0346780704 scopus 로고    scopus 로고
    • A comparative reappraisal of projections from the superficial laminae of the dorsal horn in the rat: The forebrain
    • doi: 10.1002/cne.10873
    • Gauriau, C., and Bernard, J.-F. (2004). A comparative reappraisal of projections from the superficial laminae of the dorsal horn in the rat: the forebrain. J. Comp. Neurol. 468, 24-56. doi: 10.1002/cne.10873
    • (2004) J. Comp. Neurol. , vol.468 , pp. 24-56
    • Gauriau, C.1    Bernard, J.-F.2
  • 15
    • 78149359626 scopus 로고    scopus 로고
    • Nociceptor sensitization in pain pathogenesis
    • doi: 10.1038/nm.2235
    • Gold, M. S., and Gebhart, G. F. (2010). Nociceptor sensitization in pain pathogenesis. Nat. Med. 16, 1248-1257. doi: 10.1038/nm.2235
    • (2010) Nat. Med. , vol.16 , pp. 1248-1257
    • Gold, M.S.1    Gebhart, G.F.2
  • 16
    • 2342642103 scopus 로고    scopus 로고
    • Synaptic plasticity in the amygdala in a visceral pain model in rats
    • doi: 10.1016/j.neulet.2003.12.027
    • Han, J. S., and Neugebauer, V. (2004). Synaptic plasticity in the amygdala in a visceral pain model in rats. Neurosci. Lett. 361, 254-257. doi: 10.1016/j.neulet.2003.12.027
    • (2004) Neurosci. Lett. , vol.361 , pp. 254-257
    • Han, J.S.1    Neugebauer, V.2
  • 17
    • 84860764922 scopus 로고    scopus 로고
    • Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors
    • doi: 10.1016/j.cub.2012.02.066
    • Husson, S. J., Costa, W. S., Wabnig, S., Stirman, J. N., Watson, J. D., Spencer, W. C., et al. (2012). Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors. Curr. Biol. 22, 743-752. doi: 10.1016/j.cub.2012.02.066
    • (2012) Curr. Biol. , vol.22 , pp. 743-752
    • Husson, S.J.1    Costa, W.S.2    Wabnig, S.3    Stirman, J.N.4    Watson, J.D.5    Spencer, W.C.6
  • 18
    • 84867072318 scopus 로고    scopus 로고
    • Modulation of medial prefrontal cortical activity using in vivo recordings and optogenetics
    • doi: 10.1186/1756-6606-5-36
    • Ji, G., and Neugebauer, V. (2012). Modulation of medial prefrontal cortical activity using in vivo recordings and optogenetics. Mol. Brain. 5:36. doi: 10.1186/1756-6606-5-36
    • (2012) Mol. Brain. , vol.5 , pp. 36
    • Ji, G.1    Neugebauer, V.2
  • 19
    • 84875457497 scopus 로고    scopus 로고
    • Photochemical activation of TRPA1 channels in neurons and animals
    • doi: 10.1038/nchembio.1183
    • Kokel, D., Cheung, C. Y. J., Mills, R., Coutinho-Budd, J., Huang, L., Setola, V., et al. (2013). Photochemical activation of TRPA1 channels in neurons and animals. Nat. Chem. Biol. 9, 257-263. doi: 10.1038/nchembio.1183
    • (2013) Nat. Chem. Biol. , vol.9 , pp. 257-263
    • Kokel, D.1    Cheung, C.Y.J.2    Mills, R.3    Coutinho-Budd, J.4    Huang, L.5    Setola, V.6
  • 20
    • 84880688248 scopus 로고    scopus 로고
    • Optogenetic pharmacology for control of native neuronal signaling proteins
    • doi: 10.1038/nn.3424
    • Kramer, R. H., Mourot, A., and Adesnik, H. (2013). Optogenetic pharmacology for control of native neuronal signaling proteins. Nat. Neurosci. 16, 816-823. doi: 10.1038/nn.3424
    • (2013) Nat. Neurosci. , vol.16 , pp. 816-823
    • Kramer, R.H.1    Mourot, A.2    Adesnik, H.3
  • 21
    • 79955590739 scopus 로고    scopus 로고
    • Prescription opioid abuse, pain and addiction: Clinical issues and implications
    • doi: 10.1111/j.1465-3362.2010.00271.x
    • Ling, W., Mooney, L., and Hillhouse, M. (2011). Prescription opioid abuse, pain and addiction: clinical issues and implications. Drug Alcohol Rev. 30, 300-305. doi: 10.1111/j.1465-3362.2010.00271.x
    • (2011) Drug Alcohol Rev. , vol.30 , pp. 300-305
    • Ling, W.1    Mooney, L.2    Hillhouse, M.3
  • 22
    • 84883515305 scopus 로고    scopus 로고
    • A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia
    • doi: 10.1172/jci70026
    • Lu, Y., Dong, H., Gao, Y., Gong, Y., Ren, Y., Gu, N., et al. (2013). A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia. J. Clin. Invest. 123, 4050-4062. doi: 10.1172/jci70026
    • (2013) J. Clin. Invest. , vol.123 , pp. 4050-4062
    • Lu, Y.1    Dong, H.2    Gao, Y.3    Gong, Y.4    Ren, Y.5    Gu, N.6
  • 23
    • 0033174498 scopus 로고    scopus 로고
    • From the gate to the neuromatrix
    • doi: 10.1016/s0304-3959(99)00145-1
    • Melzack, R. (1999). From the gate to the neuromatrix. Pain 82(Suppl. 6), S121-S126. doi: 10.1016/s0304-3959(99)00145-1
    • (1999) Pain , vol.82 , Issue.SUPPL. 6
    • Melzack, R.1
  • 24
    • 84860270785 scopus 로고    scopus 로고
    • Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons
    • doi: 10.1038/ncomms1795
    • Minett, M. S., Nassar, M. A., Clark, A. K., Passmore, G., Dickenson, A. H., Wang, F., et al. (2012). Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons. Nat. Commun. 3:791. doi: 10.1038/ncomms1795
    • (2012) Nat. Commun. , vol.3 , pp. 791
    • Minett, M.S.1    Nassar, M.A.2    Clark, A.K.3    Passmore, G.4    Dickenson, A.H.5    Wang, F.6
  • 25
    • 0036703985 scopus 로고    scopus 로고
    • Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord
    • Moore, K. A., Kohno, T., Karchewski, L. A., Scholz, J., Baba, H., and Woolf, C. J. (2002). Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord. J. Neurosci. 22, 6724-6731.
    • (2002) J. Neurosci. , vol.22 , pp. 6724-6731
    • Moore, K.A.1    Kohno, T.2    Karchewski, L.A.3    Scholz, J.4    Baba, H.5    Woolf, C.J.6
  • 26
    • 29044433616 scopus 로고    scopus 로고
    • Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses
    • doi: 10.1016/j.cub.2005.11.032
    • Nagel, G., Brauner, M., Liewald, J. F., Adeishvili, N., Bamberg, E., and Gottschalk, A. (2005). Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Curr. Biol. 15, 2279-2284. doi: 10.1016/j.cub.2005.11.032
    • (2005) Curr. Biol. , vol.15 , pp. 2279-2284
    • Nagel, G.1    Brauner, M.2    Liewald, J.F.3    Adeishvili, N.4    Bamberg, E.5    Gottschalk, A.6
  • 27
    • 78049450440 scopus 로고    scopus 로고
    • Central modulation of pain
    • doi: 10.1172/JCI43766
    • Ossipov, M. H., Dussor, G. O., and Porreca, F. (2010). Central modulation of pain. J. Clin. Invest. 120, 3779-3787. doi: 10.1172/JCI43766
    • (2010) J. Clin. Invest. , vol.120 , pp. 3779-3787
    • Ossipov, M.H.1    Dussor, G.O.2    Porreca, F.3
  • 28
    • 78651412373 scopus 로고    scopus 로고
    • Epidemiology of chronic non-cancer pain in Europe: Narrative review of prevalence, pain treatments and pain impact
    • doi: 10.1185/03007995.2010.545813
    • Reid, K. J., Harker, J., Bala, M. M., Truyers, C., Kellen, E., Bekkering, G. E., et al. (2011). Epidemiology of chronic non-cancer pain in Europe: narrative review of prevalence, pain treatments and pain impact. Curr. Med. Res. Opin. 27, 449-462. doi: 10.1185/03007995.2010.545813
    • (2011) Curr. Med. Res. Opin. , vol.27 , pp. 449-462
    • Reid, K.J.1    Harker, J.2    Bala, M.M.3    Truyers, C.4    Kellen, E.5    Bekkering, G.E.6
  • 29
    • 0033140059 scopus 로고    scopus 로고
    • Central nervous system plasticity and persistent pain
    • discussion 164-171
    • Ren, K., and Dubner, R. (1999). Central nervous system plasticity and persistent pain. J. Orofac. Pain 13, 155-163; discussion 164-171.
    • (1999) J. Orofac. Pain , vol.13 , pp. 155-163
    • Ren, K.1    Dubner, R.2
  • 30
    • 71449102022 scopus 로고    scopus 로고
    • Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors
    • doi: 10.1038/nature08505
    • Seal, R. P., Wang, X., Guan, Y., Raja, S. N., Woodbury, C. J., Basbaum, A. I., et al. (2009). Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors. Nature 462, 651-655. doi: 10.1038/nature08505
    • (2009) Nature , vol.462 , pp. 651-655
    • Seal, R.P.1    Wang, X.2    Guan, Y.3    Raja, S.N.4    Woodbury, C.J.5    Basbaum, A.I.6
  • 31
    • 11144267215 scopus 로고    scopus 로고
    • Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice
    • doi: 10.1016/j.pain.2004.08.015
    • Stirling, L. C., Forlani, G., Baker, M. D., Wood, J. N., Matthews, E. A., Dickenson, A. H., et al. (2005). Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice. Pain 113, 27-36. doi: 10.1016/j.pain.2004.08.015
    • (2005) Pain , vol.113 , pp. 27-36
    • Stirling, L.C.1    Forlani, G.2    Baker, M.D.3    Wood, J.N.4    Matthews, E.A.5    Dickenson, A.H.6
  • 32
    • 4644251948 scopus 로고    scopus 로고
    • Invertebrate nociception: Behaviors, neurons and molecules
    • doi: 10.1002/neu.20082
    • Tobin, D. M., and Bargmann, C. I. (2004). Invertebrate nociception: behaviors, neurons and molecules. J. Neurobiol. 61, 161-174. doi: 10.1002/neu.20082
    • (2004) J. Neurobiol. , vol.61 , pp. 161-174
    • Tobin, D.M.1    Bargmann, C.I.2
  • 33
    • 78650517458 scopus 로고    scopus 로고
    • Neuronal circuitry for pain processing in the dorsal horn
    • doi: 10.1038/nrn2947
    • Todd, A. J. (2010). Neuronal circuitry for pain processing in the dorsal horn. Nat. Rev. Neurosci. 11, 823-836. doi: 10.1038/nrn2947
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 823-836
    • Todd, A.J.1
  • 34
    • 34547451102 scopus 로고    scopus 로고
    • The Cerebral signature for pain perception and its modulation
    • doi: 10.1016/j.neuron.2007.07.012
    • Tracey, I., and Mantyh, P. W. (2007). The Cerebral signature for pain perception and its modulation. Neuron 55, 377-391. doi: 10.1016/j.neuron.2007.07.012
    • (2007) Neuron , vol.55 , pp. 377-391
    • Tracey, I.1    Mantyh, P.W.2
  • 35
    • 84856269228 scopus 로고    scopus 로고
    • The thermo-TRP ion channel family: Properties and therapeutic implications
    • doi: 10.1111/j.1476-5381.2011.01601.x
    • Vay, L., Gu, C., and McNaughton, P. A. (2012). The thermo-TRP ion channel family: properties and therapeutic implications. Br. J. Pharmacol. 165, 787-801. doi: 10.1111/j.1476-5381.2011.01601.x
    • (2012) Br. J. Pharmacol. , vol.165 , pp. 787-801
    • Vay, L.1    Gu, C.2    McNaughton, P.A.3
  • 36
    • 84876793466 scopus 로고    scopus 로고
    • Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch
    • doi: 10.1016/j.neuron.2013.03.001
    • Wang, X., Zhang, J., Eberhart, D., Urban, R., Meda, K., Solorzano, C., et al. (2013). Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch. Neuron 78, 312-324. doi: 10.1016/j.neuron.2013.03.001
    • (2013) Neuron , vol.78 , pp. 312-324
    • Wang, X.1    Zhang, J.2    Eberhart, D.3    Urban, R.4    Meda, K.5    Solorzano, C.6
  • 37
    • 70350323716 scopus 로고    scopus 로고
    • Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons
    • doi: 10.1523/jneurosci.3248-09.2009
    • Wang, H., and Zylka, M. J. (2009). Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons. J. Neurosci. 29, 13202-13209. doi: 10.1523/jneurosci.3248-09.2009
    • (2009) J. Neurosci. , vol.29 , pp. 13202-13209
    • Wang, H.1    Zylka, M.J.2
  • 38
    • 0033621115 scopus 로고    scopus 로고
    • Thermal avoidance in Caenorhabditis elegans: An approach to the study of nociception
    • doi: 10.1073/pnas.96.18.10477
    • Wittenburg, N., and Baumeister, R. (1999). Thermal avoidance in Caenorhabditis elegans: an approach to the study of nociception. Proc. Natl. Acad. Sci. U S A 96, 10477-10482. doi: 10.1073/pnas.96.18.10477
    • (1999) Proc. Natl. Acad. Sci. U S A , vol.96 , pp. 10477-10482
    • Wittenburg, N.1    Baumeister, R.2


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