Design and functional evaluation of an optically active μ-opioid receptor

European Journal of Pharmacology

Volumn 705, Issue 1-3, 2013, Pages 42-48

  Barish, Philip A ^a   Xu, Ying ^b   Li, Jianxin ^b   Sun, Jiao ^b   Jarajapu, Yagna P R ^c   Ogle, William O ^a  

^a University of Florida   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

^c NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

opioid receptor; Calcium influx; cAMP; Optogenetics; Rhodopsin

Indexed keywords

CALCIUM ION; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FORSKOLIN; GUANYLATE CYCLASE; MU OPIATE RECEPTOR; OPTICALLY ACTIVE MU OPIATE RECEPTOR; POTASSIUM; RHODOPSIN; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; PHOTOACTIVATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STIMULATION; TRANSCRIPTION INITIATION;

ANALGESICS, OPIOID; BRAIN-DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; HEK293 CELLS; HUMANS; OPTOGENETICS; PHOTIC STIMULATION; RECEPTORS, OPIOID, MU; RHODOPSIN;

EID: 84875325415     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.01.065     Document Type: Article

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