메뉴 건너뛰기




Volumn 19, Issue 2, 2014, Pages 327-333

Shikonin suppresses IL-17-induced VEGF expression via blockage of JAK2/STAT3 pathway

Author keywords

IL 17; Shikonin; STAT3; VEGF

Indexed keywords

CD34 ANTIGEN; DRUG VEHICLE; INTERLEUKIN 17; JANUS KINASE 2; MESSENGER RNA; SHIKONIN; STAT3 PROTEIN; VASCULOTROPIN;

EID: 84896900555     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.01.027     Document Type: Article
Times cited : (72)

References (29)
  • 2
    • 13444301227 scopus 로고    scopus 로고
    • Psoriasis: More than skin deep
    • M.R. Pittelkow Psoriasis: more than skin deep Nat Med 11 2005 17 18
    • (2005) Nat Med , vol.11 , pp. 17-18
    • Pittelkow, M.R.1
  • 3
    • 85046165524 scopus 로고    scopus 로고
    • Animal models of psoriasis
    • B.J. Nickoloff, and T. Wrone-Smith Animal models of psoriasis Nat Med 3 1997 475 476
    • (1997) Nat Med , vol.3 , pp. 475-476
    • Nickoloff, B.J.1    Wrone-Smith, T.2
  • 4
    • 33847757147 scopus 로고    scopus 로고
    • Cracking the cytokine code in psoriasis
    • B.J. Nickoloff Cracking the cytokine code in psoriasis Nat Med 13 2007 242 244
    • (2007) Nat Med , vol.13 , pp. 242-244
    • Nickoloff, B.J.1
  • 6
    • 43049148701 scopus 로고    scopus 로고
    • Angiogenesis: The new potential target for the therapy of psoriasis?
    • R. Heidenreich, M. Rocken, and K. Ghoreschi Angiogenesis: the new potential target for the therapy of psoriasis? Drug News Perspect 21 2008 97 105
    • (2008) Drug News Perspect , vol.21 , pp. 97-105
    • Heidenreich, R.1    Rocken, M.2    Ghoreschi, K.3
  • 7
    • 0035887627 scopus 로고    scopus 로고
    • Cutting edge: IL-17 F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production
    • T. Starnes, M.J. Robertson, G. Sledge, S. Kelich, H. Nakshatri, and H.E. Broxmeyer et al. Cutting edge: IL-17 F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production J Immunol 167 2001 4137 4140
    • (2001) J Immunol , vol.167 , pp. 4137-4140
    • Starnes, T.1    Robertson, M.J.2    Sledge, G.3    Kelich, S.4    Nakshatri, H.5    Broxmeyer, H.E.6
  • 9
    • 33646552450 scopus 로고    scopus 로고
    • IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis
    • K. Wolk, E. Witte, E. Wallace, W.D. Döcke, S. Kunz, and K. Asadullah et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis Eur J Immunol 36 2006 1309 1323
    • (2006) Eur J Immunol , vol.36 , pp. 1309-1323
    • Wolk, K.1    Witte, E.2    Wallace, E.3    Döcke, W.D.4    Kunz, S.5    Asadullah, K.6
  • 10
    • 33846906224 scopus 로고    scopus 로고
    • Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • Y. Zheng, D.M. Danilenko, P. Valdez, I. Kasman, J. Eastham-Anderson, and J. Wu et al. Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis Nature 445 2007 648 651
    • (2007) Nature , vol.445 , pp. 648-651
    • Zheng, Y.1    Danilenko, D.M.2    Valdez, P.3    Kasman, I.4    Eastham-Anderson, J.5    Wu, J.6
  • 11
    • 77958072084 scopus 로고    scopus 로고
    • Effects of AIN457, a fully human antibody to in terleukin-17 A, on psoriasis, rheumatoid arthritis and uveitis
    • W. Hueber, D.D. Patel, T. Dryja, A.M. Wright, I. Koroleva, and G. Bruin et al. Effects of AIN457, a fully human antibody to In terleukin-17 A, on psoriasis, rheumatoid arthritis and uveitis Sci Transl Med 2 2010 52ra72
    • (2010) Sci Transl Med , vol.2
    • Hueber, W.1    Patel, D.D.2    Dryja, T.3    Wright, A.M.4    Koroleva, I.5    Bruin, G.6
  • 13
    • 0035990608 scopus 로고    scopus 로고
    • Cellular pharmacology studies of shikonin derivatives
    • X. Chen, L. Yang, J.J. Oppenheim, and M.Z. Howard Cellular pharmacology studies of shikonin derivatives Phytother Res 16 2002 199 209
    • (2002) Phytother Res , vol.16 , pp. 199-209
    • Chen, X.1    Yang, L.2    Oppenheim, J.J.3    Howard, M.Z.4
  • 14
    • 0036613943 scopus 로고    scopus 로고
    • Alkannin and shikonin: Effect on free radical processes and on inflammation - A preliminary pharmacochemical investigation
    • A.P. Kourounakis, A.N. Assimopoulou, V.P. Papageorgiou, A. Gavalas, and P.N. Kourounakis Alkannin and shikonin: effect on free radical processes and on inflammation - a preliminary pharmacochemical investigation Arch Pharm (Weinheim) 335 2002 262 266
    • (2002) Arch Pharm (Weinheim) , vol.335 , pp. 262-266
    • Kourounakis, A.P.1    Assimopoulou, A.N.2    Papageorgiou, V.P.3    Gavalas, A.4    Kourounakis, P.N.5
  • 15
    • 84879468381 scopus 로고    scopus 로고
    • Shikonin promotes intestinal wound healing in vitro via induction of TGF-β release in IEC-18 cells
    • I. Andújar, J.L. Ríos, R.M. Giner, and M.C. Recio Shikonin promotes intestinal wound healing in vitro via induction of TGF-β release in IEC-18 cells Eur J Pharm Sci 49 2013 637 641
    • (2013) Eur J Pharm Sci , vol.49 , pp. 637-641
    • Andújar, I.1    Ríos, J.L.2    Giner, R.M.3    Recio, M.C.4
  • 16
    • 84883334460 scopus 로고    scopus 로고
    • Shikonin suppresses the migratory ability of hepatocellular carcinoma cells
    • P.L. Wei, C.C. Tu, C.H. Chen, Y.S. Ho, C.T. Wu, and H.Y. Su et al. Shikonin suppresses the migratory ability of hepatocellular carcinoma cells J Agric Food Chem 61 2013 8191 8197
    • (2013) J Agric Food Chem , vol.61 , pp. 8191-8197
    • Wei, P.L.1    Tu, C.C.2    Chen, C.H.3    Ho, Y.S.4    Wu, C.T.5    Su, H.Y.6
  • 18
    • 84878422114 scopus 로고    scopus 로고
    • Shikonin exerts anti-inflammatory effects in a murine model of lipopolysaccharide-induced acute lung injury by inhibiting the nuclear factor-kappaB signaling pathway
    • D. Liang, Y. Sun, Y. Shen, F. Li, X. Song, and E. Zhou et al. Shikonin exerts anti-inflammatory effects in a murine model of lipopolysaccharide-induced acute lung injury by inhibiting the nuclear factor-kappaB signaling pathway Int Immunopharmacol 16 2013 475 480
    • (2013) Int Immunopharmacol , vol.16 , pp. 475-480
    • Liang, D.1    Sun, Y.2    Shen, Y.3    Li, F.4    Song, X.5    Zhou, E.6
  • 20
    • 77951210918 scopus 로고    scopus 로고
    • Bee venom inhibits tumor angiogenesis and metastasis by inhibiting tyrosine phosphorylation of VEGFR-2 in LLC-tumor-bearing mice
    • J.E. Huh, Y.H. Baek, M.H. Lee, D.Y. Choi, D.S. Park, and J.D. Lee Bee venom inhibits tumor angiogenesis and metastasis by inhibiting tyrosine phosphorylation of VEGFR-2 in LLC-tumor-bearing mice Cancer Lett 292 2010 98 110
    • (2010) Cancer Lett , vol.292 , pp. 98-110
    • Huh, J.E.1    Baek, Y.H.2    Lee, M.H.3    Choi, D.Y.4    Park, D.S.5    Lee, J.D.6
  • 21
    • 84865136495 scopus 로고    scopus 로고
    • Recombinant human endostatin inhibits adjuvant arthritis by down-regulating VEGF expression and suppression of TNF-α, IL-1β production
    • W. Hu, L.J. Xia, F.H. Chen, F.R. Wu, J. Tang, and C.Z. Chen et al. Recombinant human endostatin inhibits adjuvant arthritis by down-regulating VEGF expression and suppression of TNF-α, IL-1β production Inflamm Res 61 2012 827 835
    • (2012) Inflamm Res , vol.61 , pp. 827-835
    • Hu, W.1    Xia, L.J.2    Chen, F.H.3    Wu, F.R.4    Tang, J.5    Chen, C.Z.6
  • 22
    • 84870813363 scopus 로고    scopus 로고
    • Interleukin-17 and interleukin-22 induced proinflammatory cytokine production in keratinocytes via inhibitor of nuclear factor κb kinase-α expression
    • K.A. Cho, J.Y. Kim, S.Y. Woo, H.J. Park, K.H. Lee, and C.U. Pae Interleukin-17 and interleukin-22 induced proinflammatory cytokine production in keratinocytes via inhibitor of nuclear factor κB kinase-α expression Ann Dermatol 24 2012 398 405
    • (2012) Ann Dermatol , vol.24 , pp. 398-405
    • Cho, K.A.1    Kim, J.Y.2    Woo, S.Y.3    Park, H.J.4    Lee, K.H.5    Pae, C.U.6
  • 24
    • 83055173953 scopus 로고    scopus 로고
    • IL-17A stimulates the production of inflammatory mediators via Erk1/2, p38 MAPK, PI3K/Akt, and NF-κB pathways in ARPE-19 cells
    • Y. Chen, A. Kijlstra, Y. Chen, and P. Yang IL-17A stimulates the production of inflammatory mediators via Erk1/2, p38 MAPK, PI3K/Akt, and NF-κB pathways in ARPE-19 cells Mol Vis 17 2011 3072 3077
    • (2011) Mol Vis , vol.17 , pp. 3072-3077
    • Chen, Y.1    Kijlstra, A.2    Chen, Y.3    Yang, P.4
  • 25
    • 65449136692 scopus 로고    scopus 로고
    • Critical role for STAT3 in IL-17A-mediated CCL11 expression in human airway smooth muscle cells
    • A. Saleh, L. Shan, A.J. Halayko, S. Kung, and A.S. Gounni Critical role for STAT3 in IL-17A-mediated CCL11 expression in human airway smooth muscle cells J Immunol 182 2009 3357 3365
    • (2009) J Immunol , vol.182 , pp. 3357-3365
    • Saleh, A.1    Shan, L.2    Halayko, A.J.3    Kung, S.4    Gounni, A.S.5
  • 26
    • 84868340664 scopus 로고    scopus 로고
    • Opposing roles of STAT-1 and STAT-3 in regulating vascular endothelial growth factor expression in vascular smooth muscle cells
    • A. Albasanz-Puig, J. Murray, M. Namekata, and E.S. Wijelath Opposing roles of STAT-1 and STAT-3 in regulating vascular endothelial growth factor expression in vascular smooth muscle cells Biochem Biophys Res Commun 428 2012 179 184
    • (2012) Biochem Biophys Res Commun , vol.428 , pp. 179-184
    • Albasanz-Puig, A.1    Murray, J.2    Namekata, M.3    Wijelath, E.S.4
  • 27
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • E. James, and J. Darnell STATs and gene regulation Science 277 1997 1630 1635
    • (1997) Science , vol.277 , pp. 1630-1635
    • James, E.1    Darnell, J.2
  • 28
    • 80054955784 scopus 로고    scopus 로고
    • Triptolide inhibits IFN-γ signaling via the Jak/STAT pathway in HaCaT keratinocytes
    • T. Hongqin, L. Xinyu, G. Heng, X. Lanfang, W. Yongfang, and S. Shasha Triptolide inhibits IFN-γ signaling via the Jak/STAT pathway in HaCaT keratinocytes Phytother Res 25 2011 1678 1685
    • (2011) Phytother Res , vol.25 , pp. 1678-1685
    • Hongqin, T.1    Xinyu, L.2    Heng, G.3    Lanfang, X.4    Yongfang, W.5    Shasha, S.6
  • 29
    • 0033828672 scopus 로고    scopus 로고
    • SOCS: Physiological suppressors of cytokine signaling
    • D.L. Krebs, and D.J. Hilton SOCS: physiological suppressors of cytokine signaling J Cell Sci 113 2000 2813 2819
    • (2000) J Cell Sci , vol.113 , pp. 2813-2819
    • Krebs, D.L.1    Hilton, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.