Recombinant human endostatin inhibits adjuvant arthritis by down-regulating VEGF expression and suppression of TNF-α, IL-1β production

Inflammation Research

Volumn 61, Issue 8, 2012, Pages 827-835

  Hu, Wei ^a   Xia, Li Juan ^a   Chen, Fei Hu ^a   Wu, Fan Rong ^a   Tang, Jie ^a   Chen, Cun Zhi ^b   Jiang, Sheng ^a   Chen, Hui Hui ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Adjuvant arthritis; IL 1 ; Recombinant human endostatin; TNF ; VEGF

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; EOSIN; HEMATOXYLIN; INTERLEUKIN 1BETA; MESSENGER RNA; RECOMBINANT ENDOSTATIN; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADJUVANT ARTHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE SEVERITY; DRUG DOSE COMPARISON; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME REPRESSION; HISTOLOGY; IMMUNIZATION; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; SYNOVIOCYTE; SYNOVIUM; TREATMENT RESPONSE;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELL PROLIFERATION; CELLS, CULTURED; DOWN-REGULATION; ENDOSTATINS; HUMANS; INTERLEUKIN-1BETA; JOINT CAPSULE; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84865136495     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-012-0477-z     Document Type: Article

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