The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells

Neurodegenerative Diseases

Volumn 13, Issue 2-3, 2014, Pages 64-68

  Kim, Doo Yeon ^a   Wertz, Mary H ^a   Gautam, Vivek ^a   D'Avanzo, Carla ^a   Bhattacharyya, Raja ^a   Kovacs, Dora M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alzheimer's disease; Presenilin; Voltage gated sodium channel

Indexed keywords

GAMMA SECRETASE; MESSENGER RNA; PRESENILIN; VOLTAGE GATED SODIUM CHANNEL BETA 2 SUBUNIT; PROTEIN; SODIUM ION;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE MUTATION; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; CELL FREE SYSTEM; CONFERENCE PAPER; FAMILIAL DISEASE; HUMAN; SODIUM CELL LEVEL; WILD TYPE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; MUTATION; NEURONS; PRESENILINS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION; VOLTAGE-GATED SODIUM CHANNELS;

EID: 84896891282     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000354669     Document Type: Article

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