Extracellular nucleotide catabolism by the Group B Streptococcus ectonucleotidase NudP increases bacterial survival in blood

Journal of Biological Chemistry

Volumn 289, Issue 9, 2014, Pages 5479-5489

  Firon, Arnaud ^a,c   Dinis, Marcia ^a,c   Raynal, Bertrand ^b   Poyart, Claire ^d,e,f   Trieu Cuot, Patrick ^a,c   Kaminski, Pierre Alexandre ^a,c  

^a INSTITUT PASTEUR   (France)

^b Plateforme de Biophysique des Macromolécules et de Leurs Interactions   (France)

^c CNRS   (France)

^d INSTITUT COCHIN   (France)

^e INSERM   (France)

^f ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL CHARACTERIZATION; EXTRACELLULAR LEVELS; EXTRACELLULAR NUCLEOTIDES; GRAM-POSITIVE BACTERIUM; GROUP B STREPTOCOCCUS; MAMMALIAN IMMUNE RESPONSE; STREPTOCOCCUS AGALACTIAE; SUBSTRATE SPECIFICITY;

BLOOD; IMMUNE SYSTEM; MAMMALS; NUCLEOTIDES; PROTEINS;

ENZYME ACTIVITY;

5' NUCLEOSIDE DIPHOSPHATE PHOSPHOHYDROLASE; ADENOSINE; MANGANESE; NUCLEOTIDASE; NUCLEOTIDE; RECOMBINANT ENZYME; SORTASE; SORTASE A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BIOCHEMISTRY; CELL WALL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; EXTRACELLULAR MATRIX; FEMALE; GENE DELETION; GENETIC CODE; GROUP B STREPTOCOCCAL INFECTION; IN VIVO STUDY; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE METABOLISM; NUCLEOTIDE SEQUENCE; PLASMA CLEARANCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MOTIF; RAT;

ADENOSINE; BACTERIAL PATHOGENESIS; ENZYME CATALYSIS; ENZYMES; HOST-PATHOGEN INTERACTIONS; METALLOENZYMES; NUCLEOSIDE NUCLEOTIDE METABOLISM; STREPTOCOCCUS;

ADENOSINE; AMINO ACID MOTIFS; ANIMALS; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICROBIAL VIABILITY; N-GLYCOSYL HYDROLASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STREPTOCOCCUS AGALACTIAE;

EID: 84896886991     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.545632     Document Type: Article

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