Ecto-5′-nucleotidase: A candidate virulence factor in Streptococcus sanguinis experimental endocarditis

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Fan, Jingyuan ^a,d   Zhang, Yongshu ^a   Chuang Smith, Olivia N ^b   Frank, Kristi L ^b   Guenther, Brian D ^a   Kern, Marissa ^a   Schlievert, Patrick M ^b   Herzberg, Mark C ^a,c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ECTO 5' NUCLEOTIDASE; INTERLEUKIN 10; INTERLEUKIN 12; 5' NUCLEOTIDASE; ADENOSINE; BACTERIAL PROTEIN; NT5E PROTEIN, STREPTOCOCCUS SANGUINIS; VIRULENCE FACTOR;

ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE DELETION; HYDROLYSIS; MACROPHAGE; MONOCYTE; NONHUMAN; NT5E GENE; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN MOTIF; STREPTOCOCCUS SANGUINIS; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; ANIMAL; BACTERIAL ENDOCARDITIS; BACTERIUM ADHERENCE; CELL WALL; ENZYMOLOGY; GENETICS; KINETICS; MASS SPECTROMETRY; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; MOLECULAR GENETICS; MUTATION; PATHOGENICITY; POLYACRYLAMIDE GEL ELECTROPHORESIS; RABBIT; STREPTOCOCCUS INFECTION; VIRULENCE;

5'-NUCLEOTIDASE; ADENOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; BACTERIAL ADHESION; BACTERIAL PROTEINS; CELL WALL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOCARDITIS, BACTERIAL; HYDROLYSIS; KINETICS; MASS SPECTROMETRY; MICROBIAL VIABILITY; MOLECULAR SEQUENCE DATA; MUTATION; PLATELET ADHESIVENESS; PLATELET AGGREGATION; RABBITS; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS SANGUIS; VIRULENCE; VIRULENCE FACTORS;

EID: 84862003617     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038059     Document Type: Article

References (51)

1. Mylonakis E, Calderwood SB, (2001) Infective endocarditis in adults. N. Engl. J. Med 345: 1318-1330.
2. Moreillon P, Que Y-A, (2004) Infective endocarditis. Lancet 363: 139-149.
3. Gould K, Ramirez-Ronda CH, Holmes RK, Sanford JP, (1975) Adherence of bacteria to heart valves in vitro. J. Clin. Invest 56: 1364-1370.
4. Herzberg MC, MacFarlane GD, Gong K, Armstrong NN, Witt AR, (1992) The platelet interactivity phenotype of Streptococcus sanguis influences the course of experimental endocarditis. Infect. Immun 60: 4809-4818.
5. Meyer MW, Witt AR, Krishnan LK, Yokota M, Roszkowski MJ, (1995) Therapeutic advantage of recombinant human plasminogen activator in endocarditis: evidence from experiments in rabbits. Thromb. Haemost 73: 680-682.
6. Yokota M, Basi DL, Herzberg MC, Meyer MW, (2001) Anti-fibrin antibody binding in valvular vegetations and kidney lesions during experimental endocarditis. Microbiol. Immunol 45: 699-707.
7. Ruggeri ZM, (2002) Platelets in atherothrombosis. Nat. Med 8: 1227-1234.
8. Herzberg MC, Krishnan LK, MacFarlane GD, (1993) Involvement of alpha 2-adrenoreceptors and G proteins in the modulation of platelet secretion in response to Streptococcus sanguis. Crit. Rev. Oral Biol. Med 4: 435-442.
9. MacFarlane GD, Sampson DE, Clawson DJ, Clawson CC, Kelly KL, (1994) Evidence for an ecto-ATPase on the cell wall of Streptococcus sanguis. Oral Microbiol. Immunol 9: 180-185.
10. Herzberg MC, Brintzenhofe KL, (1983) ADP-like platelet aggregation activity generated by viridans streptococci incubated with exogenous ATP. Infect. Immun 40: 120-125.
11. Weiss WJ, Lenoy E, Murphy T, Tardio L, Burgio P, (2004) Effect of srtA and srtB gene expression on the virulence of Staphylococcus aureus in animal models of infection. J. Antimicrob. Chemother. 53: 480-486.
12. Turner LS, Kanamoto T, Unoki T, Munro CL, Wu H, (2009) Comprehensive evaluation of Streptococcus sanguinis cell wall-anchored proteins in early infective endocarditis. Infect. Immun. 77: 4966-4975.
13. Xu P, Alves JM, Kitten T, Brown A, Chen Z, (2007) Genome of the opportunistic pathogen Streptococcus sanguinis. J. Bacteriol 189: 3166-3175.
14. Cossart P, Jonquières R, (2000) Sortase, a universal target for therapeutic agents against gram-positive bacteria? Proc. Natl. Acad. Sci. U.S.A 97: 5013-5015.
15. Zimmermann H, (1992) 5′-Nucleotidase: molecular structure and functional aspects. Biochem. J 285 (Pt 2): 345-365.
16. Woulfe D, Yang J, Brass L, (2001) ADP and platelets: the end of the beginning. J. Clin. Invest 107: 1503-1505.
17. Cristalli G, Volpini R, Vittori S, Camaioni E, Monopoli A, (1994) 2-Alkynyl derivatives of adenosine-5′-N-ethyluronamide: selective A2 adenosine receptor agonists with potent inhibitory activity on platelet aggregation. J. Med. Chem 37: 1720-1726.
18. Piccini A, Carta S, Tassi S, Lasiglié D, Fossati G, (2008) ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way. Proc. Natl. Acad. Sci. U.S.A 105: 8067-8072.
19. Le Moine O, Stordeur P, Schandene L, Marchant A, de Groote D, (1996) Adenosine enhances IL-10 secretion by human monocytes. J. Immunol. 156: 4408-4414.
20. Link AA, Kino T, Worth JA, McGuire JL, Crane ML, (2000) Ligand-Activation of the adenosine A2a receptors Inhibits IL-12 production by human monocytes. J. Immunol. 164: 436-442.
21. Soberay AH, Herzberg MC, Rudney JD, Nieuwenhuis HK, Sixma JJ, (1987) Responses of platelets to strains of Streptococcus sanguis: findings in healthy subjects, Bernard-Soulier, Glanzmann's, and collagen-unresponsive patients. Thromb. Haemost 57: 222-225.
22. Kawashima Y, Nagasawa T, Ninomiya H, (2000) Contribution of ecto-5′-nucleotidase to the inhibition of platelet aggregation by human endothelial cells. Blood 96: 2157-2162.
23. Garen A, Levinthal C, (1960) A fine-structure genetic and chemical study of the enzyme alkaline phosphatase of E. coli. I. Purification and characterization of alkaline phosphatase. Biochim. Biophys. Acta 38: 470-483.
24. Iyú D, Glenn JR, White AE, Fox SC, Heptinstall S, (2011) Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist. Arterioscler. Thromb. Vasc. Biol. 31: 416-422.
25. Herzberg MC, Brintzenhofe KL, Clawson CC, (1983) Aggregation of human platelets and adhesion of Streptococcus sanguis. Infect. Immun 39: 1457-1469.
26. Berrêdo-Pinho M, Peres-Sampaio CE, Chrispim PP, Belmont-Firpo R, Lemos AP, (2001) A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in adenosine acquisition and virulence. Arch. Biochem. Biophys. 391: 16-24.
27. Pinheiro CM, Martins-Duarte ES, Ferraro RB, Fonseca de Souza AL, Gomes MT, (2006) Leishmania amazonensis: Biological and biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities. Exp. Parasitol. 114: 16-25.
28. Thammavongsa V, Kern JW, Missiakas DM, Schneewind O, (2009) Staphylococcus aureus synthesizes adenosine to escape host immune responses. J. Exp. Med 206: 2417-2427.
29. Haskó G, Pacher P, (2008) A2A receptors in inflammation and injury: lessons learned from transgenic animals. J. Leukoc. Biol 83: 447-455.
30. Haskó G, Szabó C, Németh ZH, Kvetan V, Pastores SM, (1996) Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J. Immunol. 157: 4634-4640.
31. Haskó G, Kuhel DG, Chen JF, Schwarzschild MA, Deitch EA, (2000) Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J. 14: 2065-2074.
32. Khoa ND, Montesinos MC, Reiss AB, Delano D, Awadallah N, (2001) Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells. J. Immunol. 167: 4026-4032.
33. Meyer MW, Gong K, Herzberg MC, (1998) Streptococcus sanguis-induced platelet clotting in rabbits and hemodynamic and cardiopulmonary consequences. Infect. Immun. 66: 5906-5914.
34. Schlievert PM, Gahr PJ, Assimacopoulos AP, Dinges MM, Stoehr JA, (1998) Aggregation and binding substances enhance pathogenicity in rabbit models of Enterococcus faecalis endocarditis. Infect. Immun 66: 218-223.
35. Veltrop MHAM, Bancsi MJLMF, Bertina RM, Thompson J, (2000) Role of monocytes in experimental Staphylococcus aureus endocarditis. Infect. Immun. 68: 4818-4821.
36. Di Virgilio F, Chiozzi P, Ferrari D, Falzoni S, Sanz JM, (2001) Nucleotide receptors: an emerging family of regulatory molecules in blood cells. Blood 97: 587-600.
37. Imai M, Goepfert C, Kaczmarek E, Robson SC, (2000) CD39 modulates IL-1 release from activated endothelial cells. Biochem. Biophys. Res. Commun 270: 272-278.
38. Yeaman MR, Tang YQ, Shen AJ, Bayer AS, Selsted ME, (1997) Purification and in vitro activities of rabbit platelet microbicidal proteins. Infect. Immun 65: 1023-1031.
39. Yeaman MR, Bayer AS, (1999) Antimicrobial peptides from platelets. Drug Resist. Updat 2: 116-126.
40. Yeaman MR, (1997) The role of platelets in antimicrobial host defense. Clin. Infect. Dis 25: 951-968; quiz 969-970.
41. Yeaman MR, Sullam PM, Dazin PF, Bayer AS, (1994) Platelet microbicidal protein alone and in combination with antibiotics reduces Staphylococcus aureus adherence to platelets in vitro. Infect. Immun 62: 3416-3423.
42. Thammavongsa V, Schneewind O, Missiakas DM, (2011) Enzymatic properties of Staphylococcus aureus adenosine synthase (AdsA). BMC Biochem. 12: 56.
43. Ki MR, Yun SK, Choi KM, Hwang SY, (2011) Identification and characterization of the acid phosphatase HppA in Helicobacter pylori. J. Microbiol. Biotechnol. 21: 483-493.
44. Davies JR, Svensäter G, Herzberg MC, (2009) Identification of novel LPXTG-linked surface proteins from Streptococcus gordonii. Microbiology 155: 1977-1988.
45. Zhang Y, Lei Y, Khammanivong A, Herzberg MC, (2004) Identification of a novel two-component system in Streptococcus gordonii V288 involved in biofilm formation. Infect. Immun 72: 3489-3494.
46. Macrina FL, Evans RP, Tobian JA, Hartley DL, Clewell DB, (1983) Novel shuttle plasmid vehicles for Escherichia-Streptococcus transgeneric cloning. Gene 25: 145-150.
47. Nobbs AH, Zhang Y, Khammanivong A, Herzberg MC, (2007) Streptococcus gordonii Hsa environmentally constrains competitive binding by Streptococcus sanguinis to saliva-coated hydroxyapatite. J. Bacteriol 189: 3106-3114.
48. Dunny GM, Lee LN, LeBlanc DJ, (1991) Improved electroporation and cloning vector system for gram-positive bacteria. Appl. Environ. Microbiol 57: 1194-1201.
49. Erickson PR, Herzberg MC, (1990) Purification and partial characterization of a 65-kDa platelet aggregation-associated protein antigen from the surface of Streptococcus sanguis. J. Biol. Chem 265: 14080-14087.
50. Herzberg MC, Gong K, MacFarlane GD, Erickson PR, Soberay AH, (1990) Phenotypic characterization of Streptococcus sanguis virulence factors associated with bacterial endocarditis. Infect. Immun 58: 515-522.
51. Kilian M, Mikkelsen L, Henrichsen J, (1989) Taxonomic Study of Viridans Streptococci: Description of Streptococcus gordonii sp. nov. and emended descriptions of Streptococcus sanguis (White and Niven 1946), Streptococcus oralis (Bridge and Sneath 1982), and Streptococcus mitis (Andrewes and Horder 1906). Int. J. Syst. Bacteriol. 39: 471-484.