-
1
-
-
35448986170
-
The replication of beta cells in normal physiology, in disease and for therapy
-
10.1038/ncpendmet0647
-
Butler P. C., Meier J. J., Butler A. E., Bhushan A., The replication of beta cells in normal physiology, in disease and for therapy. Nature Clinical Practice. Endocrinology & Metabolism 2007 3 11 758 768 10.1038/ncpendmet0647
-
(2007)
Nature Clinical Practice. Endocrinology & Metabolism
, vol.3
, Issue.11
, pp. 758-768
-
-
Butler, P.C.1
Meier, J.J.2
Butler, A.E.3
Bhushan, A.4
-
2
-
-
80055115839
-
Type 2 diabetes and the aging pancreatic beta cell
-
2-s2.0-80055115839
-
Gunasekaran U., Gannon M., Type 2 diabetes and the aging pancreatic beta cell. Aging 2011 3 6 565 575 2-s2.0-80055115839
-
(2011)
Aging
, vol.3
, Issue.6
, pp. 565-575
-
-
Gunasekaran, U.1
Gannon, M.2
-
3
-
-
69249230769
-
Mammalian cell-cycle regulation: Several cdks, numerous cyclins and diverse compensatory mechanisms
-
2-s2.0-69249230769 10.1038/onc.2009.170
-
Satyanarayana A., Kaldis P., Mammalian cell-cycle regulation: several cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene 2009 28 33 2925 2939 2-s2.0-69249230769 10.1038/onc.2009.170
-
(2009)
Oncogene
, vol.28
, Issue.33
, pp. 2925-2939
-
-
Satyanarayana, A.1
Kaldis, P.2
-
4
-
-
12344318996
-
Cell proliferation and cell cycle control: A mini review
-
2-s2.0-12344318996 10.1111/j.1742-1241.2004.00284.x
-
Golias C. H., Charalabopoulos A., Charalabopoulos K., Cell proliferation and cell cycle control: a mini review. International Journal of Clinical Practice 2004 58 12 1134 1141 2-s2.0-12344318996 10.1111/j.1742-1241.2004.00284. x
-
(2004)
International Journal of Clinical Practice
, vol.58
, Issue.12
, pp. 1134-1141
-
-
Golias, C.H.1
Charalabopoulos, A.2
Charalabopoulos, K.3
-
5
-
-
84887988558
-
Trans-ethnic fine mapping identifies a novel independent locus at the 3′ end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population
-
10.1007/s00125-013-3047-1
-
Kuo J. Z., Sheu W. H., Assimes T. L., Hung Y.-J., Absher D., Chiu Y. -F., Mak J., Wang J.-S., Kwon S., Hsu C.-C., Trans-ethnic fine mapping identifies a novel independent locus at the 3′ end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population. Diabetologia 2013 56 12 2619 2628 10.1007/s00125-013-3047-1
-
(2013)
Diabetologia
, vol.56
, Issue.12
, pp. 2619-2628
-
-
Kuo, J.Z.1
Sheu, W.H.2
Assimes, T.L.3
Hung, Y.-J.4
Absher, D.5
Chiu, Y.-F.6
Mak, J.7
Wang, J.-S.8
Kwon, S.9
Hsu, C.-C.10
-
6
-
-
84896742854
-
Assessing the contribution of 38 genetic loci to the risk of type 2 diabetes in the Saudi Arabian population
-
10.1111/cen.12187
-
Al-Daghri N. M., Alkharfy K. M., Alokail M. S., Alenad A. M., Al-Attas O. S., Mohammed A. K., Sabico S., Albagha O. M. E., Assessing the contribution of 38 genetic loci to the risk of type 2 diabetes in the Saudi Arabian population. Clinical Endocrinology 2013 10.1111/cen.12187
-
(2013)
Clinical Endocrinology
-
-
Al-Daghri, N.M.1
Alkharfy, K.M.2
Alokail, M.S.3
Alenad, A.M.4
Al-Attas, O.S.5
Mohammed, A.K.6
Sabico, S.7
Albagha, O.M.E.8
-
7
-
-
84866755863
-
European genetic variants associated with type 2 diabetes in North African arabs
-
2-s2.0-84858974639 10.1016/j.diabet.2012.02.003
-
Cauchi S., Ezzidi I., El Achhab Y., Mtiraoui N., Chaieb L., Salah D., Nejjari C., Labrune Y., Yengo L., Beury D., Vaxillaire M., Mahjoub T., Chikri M., Froguel P., European genetic variants associated with type 2 diabetes in North African arabs. Diabetes & Metabolism 2012 38 4 316 323 2-s2.0-84858974639 10.1016/j.diabet.2012.02.003
-
(2012)
Diabetes & Metabolism
, vol.38
, Issue.4
, pp. 316-323
-
-
Cauchi, S.1
Ezzidi, I.2
El Achhab, Y.3
Mtiraoui, N.4
Chaieb, L.5
Salah, D.6
Nejjari, C.7
Labrune, Y.8
Yengo, L.9
Beury, D.10
Vaxillaire, M.11
Mahjoub, T.12
Chikri, M.13
Froguel, P.14
-
8
-
-
67650248695
-
Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population
-
2-s2.0-67650248695 10.2337/db08-1494
-
Takeuchi F., Serizawa M., Yamamoto K., Fujisawa T., Nakashima E., Ohnaka K., Ikegami H., Sugiyama T., Katsuya T., Miyagishi M., Nakashima N., Nawata H., Nakamura J., Kono S., Takayanagi R., Kato N., Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes 2009 58 7 1690 1699 2-s2.0-67650248695 10.2337/db08-1494
-
(2009)
Diabetes
, vol.58
, Issue.7
, pp. 1690-1699
-
-
Takeuchi, F.1
Serizawa, M.2
Yamamoto, K.3
Fujisawa, T.4
Nakashima, E.5
Ohnaka, K.6
Ikegami, H.7
Sugiyama, T.8
Katsuya, T.9
Miyagishi, M.10
Nakashima, N.11
Nawata, H.12
Nakamura, J.13
Kono, S.14
Takayanagi, R.15
Kato, N.16
-
9
-
-
50049086521
-
The emerging genetic architecture of type 2 diabetes
-
2-s2.0-50049086521 10.1016/j.cmet.2008.08.006
-
Doria A., Patti M.-E., Kahn C. R., The emerging genetic architecture of type 2 diabetes. Cell Metabolism 2008 8 3 186 200 2-s2.0-50049086521 10.1016/j.cmet.2008.08.006
-
(2008)
Cell Metabolism
, vol.8
, Issue.3
, pp. 186-200
-
-
Doria, A.1
Patti, M.-E.2
Kahn, C.R.3
-
10
-
-
84885421852
-
The relationship between five widely-evaluated variants in CDKN2A/B and CDKAL1 genes and the risk of type 2 diabetes: A meta-analysis
-
10.1016/j.gene.2013.08.075
-
Peng F., Hu D., Gu C., Li X., Li Y., Jia N., Chu S., Lin J., Niu W., The relationship between five widely-evaluated variants in CDKN2A/B and CDKAL1 genes and the risk of type 2 diabetes: a meta-analysis. Gene 2013 531 2 435 443 10.1016/j.gene.2013.08.075
-
(2013)
Gene
, vol.531
, Issue.2
, pp. 435-443
-
-
Peng, F.1
Hu, D.2
Gu, C.3
Li, X.4
Li, Y.5
Jia, N.6
Chu, S.7
Lin, J.8
Niu, W.9
-
11
-
-
84877038260
-
Association study of genetic variants of 17 diabetes-related genes/loci and cardiovascular risk and diabetic nephropathy in the Chinese She population
-
10.1111/1753-0407.12025
-
Chen G., Xu Y., Lin Y., Lai X., Yao J., Huang B., Chen Z., Huang H., Fu X., Lin L., Lai S., Wen J., Association study of genetic variants of 17 diabetes-related genes/loci and cardiovascular risk and diabetic nephropathy in the Chinese She population. Journal of Diabetes 2013 5 2 136 145 10.1111/1753-0407.12025
-
(2013)
Journal of Diabetes
, vol.5
, Issue.2
, pp. 136-145
-
-
Chen, G.1
Xu, Y.2
Lin, Y.3
Lai, X.4
Yao, J.5
Huang, B.6
Chen, Z.7
Huang, H.8
Fu, X.9
Lin, L.10
Lai, S.11
Wen, J.12
-
12
-
-
84885418775
-
Association between type 2 diabetes and rs10811661 polymorphism upstream of CDKN2A/B: A meta-analysis
-
10.1007/s00592-012-0400-7
-
Li H., Tang X., Liu Q., Wang Y., Association between type 2 diabetes and rs10811661 polymorphism upstream of CDKN2A/B: a meta-analysis. Acta Diabetologica 2013 50 5 657 662 10.1007/s00592-012-0400-7
-
(2013)
Acta Diabetologica
, vol.50
, Issue.5
, pp. 657-662
-
-
Li, H.1
Tang, X.2
Liu, Q.3
Wang, Y.4
-
13
-
-
84868328739
-
Association between 9p21 genetic variants and mortality risk in a prospective cohort of patients with type 2 diabetes (ZODIAC-15)
-
10.1186/1475-2840-11-138,11138
-
Landman G. W., van Vliet-Ostaptchouk J. V., Kleefstra N., van Hateren K. J. J., Drion I., Groenier K. H., Gans R. O. B., Snieder H., Hofker M. H., Bilo H. J. G., Association between 9p21 genetic variants and mortality risk in a prospective cohort of patients with type 2 diabetes (ZODIAC-15). Cardiovascular Diabetology 2012 11, article 138 10.1186/1475-2840-11-138
-
(2012)
Cardiovascular Diabetology
-
-
Landman, G.W.1
Van Vliet-Ostaptchouk, J.V.2
Kleefstra, N.3
Van Hateren, K.J.J.4
Drion, I.5
Groenier, K.H.6
Gans, R.O.B.7
Snieder, H.8
Hofker, M.H.9
Bilo, H.J.G.10
-
14
-
-
84870311448
-
Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population
-
10.2337/db11-0550
-
Gamboa-Melendez M. A., Huerta-Chagoya A., Moreno-Macias H., Vázquez-Cárdenas P., Ordóñez-Sánchez M. L., Rodríguez-Guillén R., Riba L., Rodríguez-Torres M., Guerra-García M. T., Guillén-Pineda L. E., Choudhry S., Del Bosque-Plata L., Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population. Diabetes 2012 61 12 3314 3321 10.2337/db11-0550
-
(2012)
Diabetes
, vol.61
, Issue.12
, pp. 3314-3321
-
-
Gamboa-Melendez, M.A.1
Huerta-Chagoya, A.2
Moreno-Macias, H.3
Vázquez-Cárdenas, P.4
Ordóñez-Sánchez, M.L.5
Rodríguez-Guillén, R.6
Riba, L.7
Rodríguez-Torres, M.8
Guerra-García, M.T.9
Guillén-Pineda, L.E.10
Choudhry, S.11
Del Bosque-Plata, L.12
-
15
-
-
84856349504
-
Replication study of common variants in CDKAL1 and CDKN2A/2B genes associated with type 2 diabetes in Lebanese Arab population
-
2-s2.0-84856349504 10.1016/j.diabres.2011.11.002
-
Nemr R., Almawi A. W., Echtay A., Sater M. S., Daher H. S., Almawi W. Y., Replication study of common variants in CDKAL1 and CDKN2A/2B genes associated with type 2 diabetes in Lebanese Arab population. Diabetes Research and Clinical Practice 2012 95 2 e37 e40 2-s2.0-84856349504 10.1016/j.diabres.2011.11.002
-
(2012)
Diabetes Research and Clinical Practice
, vol.95
, Issue.2
-
-
Nemr, R.1
Almawi, A.W.2
Echtay, A.3
Sater, M.S.4
Daher, H.S.5
Almawi, W.Y.6
-
16
-
-
84856714312
-
Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs
-
2-s2.0-84856714312 10.1007/s00125-011-2355-6
-
Gupta V., Vinay D. G., Rafiq S., Kranthikumar M. V., Janipalli C. S., Giambartolomei C., Evans D. M., Mani K. R., Sandeep M. N., Taylor A. E., Kinra S., Sullivan R. M., Bowen L., Timpson N. J., Smith G. D., Dudbridge F., Prabhakaran D., Ben-Shlomo Y., Reddy K. S., Ebrahim S., Chandak G. R., Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs. Diabetologia 2012 55 2 349 357 2-s2.0-84856714312 10.1007/s00125-011-2355-6
-
(2012)
Diabetologia
, vol.55
, Issue.2
, pp. 349-357
-
-
Gupta, V.1
Vinay, D.G.2
Rafiq, S.3
Kranthikumar, M.V.4
Janipalli, C.S.5
Giambartolomei, C.6
Evans, D.M.7
Mani, K.R.8
Sandeep, M.N.9
Taylor, A.E.10
Kinra, S.11
Sullivan, R.M.12
Bowen, L.13
Timpson, N.J.14
Smith, G.D.15
Dudbridge, F.16
Prabhakaran, D.17
Ben-Shlomo, Y.18
Reddy, K.S.19
Ebrahim, S.20
Chandak, G.R.21
more..
-
17
-
-
47749124258
-
Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value
-
2-s2.0-47749124258 10.1371/journal.pone.0002031 e2031
-
Cauchi S., Meyre D., Durand E., Proença C., Marre M., Hadjadj S., Choquet H., De Graeve F., Gaget S., Allegaert F., Delplanque J., Permutt M. A., Wasson J., Blech I., Charpentier G., Balkau B., Vergnaud A.-C., Czernichow S., Patsch W., Chikri M., Glaser B., Sladek R., Froguel P., Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value. PLoS ONE 2008 3 5 2-s2.0-47749124258 10.1371/journal.pone.0002031 e2031
-
(2008)
PLoS ONE
, vol.3
, Issue.5
-
-
Cauchi, S.1
Meyre, D.2
Durand, E.3
Proença, C.4
Marre, M.5
Hadjadj, S.6
Choquet, H.7
De Graeve, F.8
Gaget, S.9
Allegaert, F.10
Delplanque, J.11
Permutt, M.A.12
Wasson, J.13
Blech, I.14
Charpentier, G.15
Balkau, B.16
Vergnaud, A.-C.17
Czernichow, S.18
Patsch, W.19
Chikri, M.20
Glaser, B.21
Sladek, R.22
Froguel, P.23
more..
-
18
-
-
41849124479
-
Strong association of common variants in the CDKN2A/CDKN2B region with type 2 diabetes in French europids
-
2-s2.0-41849124479 10.1007/s00125-008-0973-4
-
Duesing K., Fatemifar G., Charpentier G., Marre M., Tichet J., Hercberg S., Balkau B., Froguel P., Gibson F., Strong association of common variants in the CDKN2A/CDKN2B region with type 2 diabetes in French europids. Diabetologia 2008 51 5 821 826 2-s2.0-41849124479 10.1007/s00125-008-0973-4
-
(2008)
Diabetologia
, vol.51
, Issue.5
, pp. 821-826
-
-
Duesing, K.1
Fatemifar, G.2
Charpentier, G.3
Marre, M.4
Tichet, J.5
Hercberg, S.6
Balkau, B.7
Froguel, P.8
Gibson, F.9
-
19
-
-
79953812139
-
Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B
-
2-s2.0-79953812139 10.1007/s00125-010-2038-8
-
Hribal M. L., Presta I., Procopio T., Marini M. A., Stančá ková A., Kuusisto J., Andreozzi F., Hammarstedt A., Jansson P.-A., Grarup N., Hansen T., Walker M., Stefan N., Fritsche A., Häring H. U., Pedersen O., Smith U., Laakso M., Sesti G., Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B. Diabetologia 2011 54 4 795 802 2-s2.0-79953812139 10.1007/s00125-010-2038-8
-
(2011)
Diabetologia
, vol.54
, Issue.4
, pp. 795-802
-
-
Hribal, M.L.1
Presta, I.2
Procopio, T.3
Marini, M.A.4
Stančá ková, A.5
Kuusisto, J.6
Andreozzi, F.7
Hammarstedt, A.8
Jansson, P.-A.9
Grarup, N.10
Hansen, T.11
Walker, M.12
Stefan, N.13
Fritsche, A.14
Häring, H.U.15
Pedersen, O.16
Smith, U.17
Laakso, M.18
Sesti, G.19
-
20
-
-
84857504660
-
Cellular senescence and tumor suppressor gene p16
-
2-s2.0-84857504660 10.1002/ijc.27316
-
Rayess H., Wang M. B., Srivatsan E. S., Cellular senescence and tumor suppressor gene p16. International Journal of Cancer 2012 130 8 1715 1725 2-s2.0-84857504660 10.1002/ijc.27316
-
(2012)
International Journal of Cancer
, vol.130
, Issue.8
, pp. 1715-1725
-
-
Rayess, H.1
Wang, M.B.2
Srivatsan, E.S.3
-
21
-
-
85047688974
-
Human pancreatic beta-cell G1/S molecule cell cycle atlas
-
10.2337/db12-0777
-
Fiaschi-Taesch N. M., Kleinberger J. W., Salim F. G., Troxell R., Wills R., Tanwir M., Casinelli G., Cox A. E., Takane K. K., Scott D. K., Stewart A. F., Human pancreatic beta-cell G1/S molecule cell cycle atlas. Diabetes 2013 62 7 2450 2459 10.2337/db12-0777
-
(2013)
Diabetes
, vol.62
, Issue.7
, pp. 2450-2459
-
-
Fiaschi-Taesch, N.M.1
Kleinberger, J.W.2
Salim, F.G.3
Troxell, R.4
Wills, R.5
Tanwir, M.6
Casinelli, G.7
Cox, A.E.8
Takane, K.K.9
Scott, D.K.10
Stewart, A.F.11
-
22
-
-
85047688791
-
Cytoplasmic-nuclear trafficking of G1/S cell cycle molecules and adult human beta-cell replication: A revised model of human beta-cell G1/S control
-
10.2337/db12-0778
-
Fiaschi-Taesch N. M., Kleinberger J. W., Salim F. G., Troxell R., Wills R., Tanwir M., Casinelli G., Cox A. E., Takane K. K., Srinivas H., Cytoplasmic-nuclear trafficking of G1/S cell cycle molecules and adult human beta-cell replication: a revised model of human beta-cell G1/S control. Diabetes 2013 62 7 2460 2470 10.2337/db12-0778
-
(2013)
Diabetes
, vol.62
, Issue.7
, pp. 2460-2470
-
-
Fiaschi-Taesch, N.M.1
Kleinberger, J.W.2
Salim, F.G.3
Troxell, R.4
Wills, R.5
Tanwir, M.6
Casinelli, G.7
Cox, A.E.8
Takane, K.K.9
Srinivas, H.10
-
23
-
-
0042856301
-
Genetic rescue of Cdk4 null mice restores pancreatic β -cell proliferation but not homeostatic cell number
-
2-s2.0-0042856301 10.1038/sj.onc.1206506
-
Martín J., Hunt S. L., Dubus P., Sotillo R., Néhmé- Pélluard F., Magnuson M. A., Parlow A. F., Malumbres M., Ortega S., Barbacid M., Genetic rescue of Cdk4 null mice restores pancreatic β -cell proliferation but not homeostatic cell number. Oncogene 2003 22 34 5261 5269 2-s2.0-0042856301 10.1038/sj.onc.1206506
-
(2003)
Oncogene
, vol.22
, Issue.34
, pp. 5261-5269
-
-
Martín, J.1
Hunt, S.L.2
Dubus, P.3
Sotillo, R.4
Néhmé- Pélluard, F.5
Magnuson, M.A.6
Parlow, A.F.7
Malumbres, M.8
Ortega, S.9
Barbacid, M.10
-
24
-
-
85047690318
-
Impaired pancreatic growth, β cell mass, and β cell function in E2F 1 - / - mice
-
2-s2.0-2342593385 10.1172/JCI200418555
-
Fajas L., Annicotte J.-S., Miard S., Sarruf D., Watanabe M., Auwerx J., Impaired pancreatic growth, β cell mass, and β cell function in E2F 1-/-mice. Journal of Clinical Investigation 2004 113 9 1288 1295 2-s2.0-2342593385 10.1172/JCI200418555
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.9
, pp. 1288-1295
-
-
Fajas, L.1
Annicotte, J.-S.2
Miard, S.3
Sarruf, D.4
Watanabe, M.5
Auwerx, J.6
-
25
-
-
68249090581
-
The CDK4-pRB-E2F1 pathway controls insulin secretion
-
2-s2.0-68249090581 10.1038/ncb1915
-
Annicotte J.-S., Blanchet E., Chavey C., Iankova I., Costes S., Assou S., Teyssier J., Dalle S., Sardet C., Fajas L., The CDK4-pRB-E2F1 pathway controls insulin secretion. Nature Cell Biology 2009 11 8 1017 1023 2-s2.0-68249090581 10.1038/ncb1915
-
(2009)
Nature Cell Biology
, vol.11
, Issue.8
, pp. 1017-1023
-
-
Annicotte, J.-S.1
Blanchet, E.2
Chavey, C.3
Iankova, I.4
Costes, S.5
Assou, S.6
Teyssier, J.7
Dalle, S.8
Sardet, C.9
Fajas, L.10
-
26
-
-
77953391682
-
The CDK4-pRB-E2F1 pathway: A new modulator of insulin secretion
-
2-s2.0-77953391682
-
Fajas L., Blanchet E., Annicotte J.-S., The CDK4-pRB-E2F1 pathway: a new modulator of insulin secretion. Islets 2010 2 1 51 53 2-s2.0-77953391682
-
(2010)
Islets
, vol.2
, Issue.1
, pp. 51-53
-
-
Fajas, L.1
Blanchet, E.2
Annicotte, J.-S.3
-
27
-
-
84879911368
-
Re-thinking cell cycle regulators: The cross-talk with metabolism
-
10.3389/fonc.2013.00004
-
Fajas L., Re-thinking cell cycle regulators: the cross-talk with metabolism. Frontiers in Oncology 2013 3, article 4 10.3389/fonc.2013.00004
-
(2013)
Frontiers in Oncology
, vol.34
-
-
Fajas, L.1
-
28
-
-
33644660954
-
Role of the forkhead protein FoxO1 in β cell compensation to insulin resistance
-
2-s2.0-33644660954 10.1172/JCI24967
-
Okamoto H., Hribal M. L., Lin H. V., Bennett W. R., Ward A., Accili D., Role of the forkhead protein FoxO1 in β cell compensation to insulin resistance. Journal of Clinical Investigation 2006 116 3 775 782 2-s2.0-33644660954 10.1172/JCI24967
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.3
, pp. 775-782
-
-
Okamoto, H.1
Hribal, M.L.2
Lin, H.V.3
Bennett, W.R.4
Ward, A.5
Accili, D.6
-
30
-
-
24144473869
-
Very slow turnover of β -cells in aged adult mice
-
2-s2.0-24144473869 10.2337/diabetes.54.9.2557
-
Teta M., Long S. Y., Wartschow L. M., Rankin M. M., Kushner J. A., Very slow turnover of β -cells in aged adult mice. Diabetes 2005 54 9 2557 2567 2-s2.0-24144473869 10.2337/diabetes.54.9.2557
-
(2005)
Diabetes
, vol.54
, Issue.9
, pp. 2557-2567
-
-
Teta, M.1
Long, S.Y.2
Wartschow, L.M.3
Rankin, M.M.4
Kushner, J.A.5
-
31
-
-
44749088201
-
β -cell replication is the primary mechanism subserving the postnatal expansion of β -cell mass in humans
-
2-s2.0-44749088201 10.2337/db07-1369
-
Meier J. J., Butler A. E., Saisho Y., Monchamp T., Galasso R., Bhushan A., Rizza R. A., Butler P. C., β -cell replication is the primary mechanism subserving the postnatal expansion of β -cell mass in humans. Diabetes 2008 57 6 1584 1594 2-s2.0-44749088201 10.2337/db07-1369
-
(2008)
Diabetes
, vol.57
, Issue.6
, pp. 1584-1594
-
-
Meier, J.J.1
Butler, A.E.2
Saisho, Y.3
Monchamp, T.4
Galasso, R.5
Bhushan, A.6
Rizza, R.A.7
Butler, P.C.8
-
32
-
-
66649084335
-
Age-dependent decline in β -cell proliferation restricts the capacity of β -cell regeneration in mice
-
2-s2.0-66649084335 10.2337/db08-1651
-
Tschen S.-I., Dhawan S., Gurlo T., Bhushan A., Age-dependent decline in β -cell proliferation restricts the capacity of β -cell regeneration in mice. Diabetes 2009 58 6 1312 1320 2-s2.0-66649084335 10.2337/db08-1651
-
(2009)
Diabetes
, vol.58
, Issue.6
, pp. 1312-1320
-
-
Tschen, S.-I.1
Dhawan, S.2
Gurlo, T.3
Bhushan, A.4
-
33
-
-
33749187810
-
P1 6 INK4a induces an age-dependent decline in islet regenerative potential
-
2-s2.0-33749187810 10.1038/nature05092
-
Krishnamurthy J., Ramsey M. R., Ligon K. L., Torrice C., Koh A., Bonner-Weir S., Sharpless N. E., p1 6 INK4a induces an age-dependent decline in islet regenerative potential. Nature 2006 443 7110 453 457 2-s2.0-33749187810 10.1038/nature05092
-
(2006)
Nature
, vol.443
, Issue.7110
, pp. 453-457
-
-
Krishnamurthy, J.1
Ramsey, M.R.2
Ligon, K.L.3
Torrice, C.4
Koh, A.5
Bonner-Weir, S.6
Sharpless, N.E.7
-
34
-
-
66249109644
-
Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence
-
2-s2.0-66249109644 10.1371/journal.pone.0005622 e5622
-
Agherbi H., Gaussmann-Wenger A., Verthuy C., Chasson L., Serrano M., Djabali M., Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence. PLoS ONE 2009 4 5 2-s2.0-66249109644 10.1371/journal.pone.0005622 e5622
-
(2009)
PLoS ONE
, vol.4
, Issue.5
-
-
Agherbi, H.1
Gaussmann-Wenger, A.2
Verthuy, C.3
Chasson, L.4
Serrano, M.5
Djabali, M.6
-
35
-
-
65249093055
-
Polycomb protein Ezh2 regulates pancreatic β -cell Ink4a/Arf expression and regeneration in diabetes mellitus
-
2-s2.0-65249093055 10.1101/gad.1742509
-
Chen H., Gu X., Su I.-H., Bottino R., Contreras J. L., Tarakhovsky A., Kim S. K., Polycomb protein Ezh2 regulates pancreatic β -cell Ink4a/Arf expression and regeneration in diabetes mellitus. Genes and Development 2009 23 8 975 985 2-s2.0-65249093055 10.1101/gad.1742509
-
(2009)
Genes and Development
, vol.23
, Issue.8
, pp. 975-985
-
-
Chen, H.1
Gu, X.2
Su, I.-H.3
Bottino, R.4
Contreras, J.L.5
Tarakhovsky, A.6
Kim, S.K.7
-
36
-
-
1942502862
-
Different Ezh2-containing complexes target methylation of histone H1 or nucleosomal histone H3
-
2-s2.0-1942502862 10.1016/S1097-2765(04)00185-6
-
Kuzmichev A., Jenuwein T., Tempst P., Reinberg D., Different Ezh2-containing complexes target methylation of histone H1 or nucleosomal histone H3. Molecular Cell 2004 14 2 183 193 2-s2.0-1942502862 10.1016/S1097-2765(04)00185-6
-
(2004)
Molecular Cell
, vol.14
, Issue.2
, pp. 183-193
-
-
Kuzmichev, A.1
Jenuwein, T.2
Tempst, P.3
Reinberg, D.4
-
37
-
-
33846148370
-
PRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p1 6 i N K 4 a tumor suppressor gene
-
2-s2.0-33846148370 10.1101/gad.1499407
-
Kotake Y., Cao R., Viatour P., Sage J., Zhang Y., Xiong Y., pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p1 6 I N K 4 a tumor suppressor gene. Genes and Development 2007 21 1 49 54 2-s2.0-33846148370 10.1101/gad.1499407
-
(2007)
Genes and Development
, vol.21
, Issue.1
, pp. 49-54
-
-
Kotake, Y.1
Cao, R.2
Viatour, P.3
Sage, J.4
Zhang, Y.5
Xiong, Y.6
-
38
-
-
79953329166
-
P53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb
-
2-s2.0-79953329166 10.1158/0008-5472.CAN-10-3483
-
Zeng Y., Kotake Y., Pei X.-H., Smith M. D., Xiong Y., p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb. Cancer Research 2011 71 7 2781 2792 2-s2.0-79953329166 10.1158/0008-5472.CAN-10- 3483
-
(2011)
Cancer Research
, vol.71
, Issue.7
, pp. 2781-2792
-
-
Zeng, Y.1
Kotake, Y.2
Pei, X.-H.3
Smith, M.D.4
Xiong, Y.5
-
39
-
-
78449243068
-
Epigenetic regulation of the INK4B-ARF-INK4a locus: In sickness and in health
-
2-s2.0-78449243068 10.4161/epi.5.8.12996
-
Popov N., Gil J., Epigenetic regulation of the INK4B-ARF-INK4a locus: in sickness and in health. Epigenetics 2010 5 8 685 690 2-s2.0-78449243068 10.4161/epi.5.8.12996
-
(2010)
Epigenetics
, vol.5
, Issue.8
, pp. 685-690
-
-
Popov, N.1
Gil, J.2
-
40
-
-
84863128509
-
The acetylation of transcription factor HBP1 by p300/CBP enhances p1 6 INK4a expression
-
2-s2.0-84856885736 10.1093/nar/gkr818
-
Wang W., Pan K., Chen Y., Huang C., Zhang X., The acetylation of transcription factor HBP1 by p300/CBP enhances p1 6 INK4a expression. Nucleic Acids Research 2012 40 3 981 995 2-s2.0-84856885736 10.1093/nar/gkr818
-
(2012)
Nucleic Acids Research
, vol.40
, Issue.3
, pp. 981-995
-
-
Wang, W.1
Pan, K.2
Chen, Y.3
Huang, C.4
Zhang, X.5
-
41
-
-
84867070330
-
Human beta cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes
-
10.1016/j.cmet.2012.08.010
-
Moran I., Akerman I., van de Bunt M., Xie R., Benazra M., Nammo T., Arnes L., Nakic N., García-Hurtado J., Rodríguez-Seguí S., Pasquali L., Human beta cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Cell Metabolism 2012 16 4 435 448 10.1016/j.cmet.2012.08.010
-
(2012)
Cell Metabolism
, vol.16
, Issue.4
, pp. 435-448
-
-
Moran, I.1
Akerman, I.2
Van De Bunt, M.3
Xie, R.4
Benazra, M.5
Nammo, T.6
Arnes, L.7
Nakic, N.8
García-Hurtado, J.9
Rodríguez-Seguí, S.10
Pasquali, L.11
-
42
-
-
79955468280
-
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p1 5 INK4B tumor suppressor gene
-
2-s2.0-79955468280 10.1038/onc.2010.568
-
Kotake Y., Nakagawa T., Kitagawa K., Suzuki S., Liu N., Kitagawa M., Xiong Y., Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p1 5 INK4B tumor suppressor gene. Oncogene 2011 30 16 1956 1962 2-s2.0-79955468280 10.1038/onc.2010.568
-
(2011)
Oncogene
, vol.30
, Issue.16
, pp. 1956-1962
-
-
Kotake, Y.1
Nakagawa, T.2
Kitagawa, K.3
Suzuki, S.4
Liu, N.5
Kitagawa, M.6
Xiong, Y.7
-
43
-
-
84874969813
-
Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway
-
10.1016/j.cellsig.2013.02.006
-
Wan G., Mathur R., Hu X., Liu Y., Zhang X., Peng G., Lu X., Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway. Cell Signal 2013 25 5 1086 1095 10.1016/j.cellsig.2013.02.006
-
(2013)
Cell Signal
, vol.25
, Issue.5
, pp. 1086-1095
-
-
Wan, G.1
Mathur, R.2
Hu, X.3
Liu, Y.4
Zhang, X.5
Peng, G.6
Lu, X.7
-
44
-
-
84877707122
-
Betatrophin: A hormone that controls pancreatic beta cell proliferation
-
10.1016/j.cell.2013.04.008
-
Yi P., Park J. S., Melton D. A., Betatrophin: a hormone that controls pancreatic beta cell proliferation. Cell 2013 153 4 747 758 10.1016/j.cell.2013. 04.008
-
(2013)
Cell
, vol.153
, Issue.4
, pp. 747-758
-
-
Yi, P.1
Park, J.S.2
Melton, D.A.3
-
45
-
-
84864501914
-
Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism
-
10.1152/ajpendo.00084.2012
-
Ren G., Kim J. Y., Smas C. M., Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism. The American Journal of Physiology-Endocrinology and Metabolism 2012 303 3 E334 E351 10.1152/ajpendo.00084.2012
-
(2012)
The American Journal of Physiology - Endocrinology and Metabolism
, vol.303
, Issue.3
-
-
Ren, G.1
Kim, J.Y.2
Smas, C.M.3
-
46
-
-
84864809680
-
Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels
-
10.1016/j.bbrc.2012.07.038
-
Zhang R., Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels. Biochemical and Biophysical Research Communications 2012 424 4 786 792 10.1016/j.bbrc.2012.07.038
-
(2012)
Biochemical and Biophysical Research Communications
, vol.424
, Issue.4
, pp. 786-792
-
-
Zhang, R.1
-
47
-
-
38149038794
-
Long-term benefits of pancreas transplantation
-
2-s2.0-38149038794 10.1097/MOT.0b013e3282f2fd7f
-
Dean P. G., Kudva Y. C., Stegall M. D., Long-term benefits of pancreas transplantation. Current Opinion in Organ Transplantation 2008 13 1 85 90 2-s2.0-38149038794 10.1097/MOT.0b013e3282f2fd7f
-
(2008)
Current Opinion in Organ Transplantation
, vol.13
, Issue.1
, pp. 85-90
-
-
Dean, P.G.1
Kudva, Y.C.2
Stegall, M.D.3
-
48
-
-
84887949665
-
Dietary energy balance modulation of Kras- and Ink4a/Ar f + / - -driven pancreatic cancer: The role of insulin-like growth factor-I
-
10.1158/1940-6207.CAPR-13-0185
-
Lashinger L. M., Harrison L. M., Rasmussen A. J., Logsdon C. D., Fischer S. M., McArthur M. J., Hursting S. D., Dietary energy balance modulation of Kras- and Ink4a/Ar f + / - driven pancreatic cancer: the role of insulin-like growth factor-I. Cancer Prevention Research 2013 6 10 1046 1055 10.1158/1940-6207.CAPR-13-0185
-
(2013)
Cancer Prevention Research
, vol.6
, Issue.10
, pp. 1046-1055
-
-
Lashinger, L.M.1
Harrison, L.M.2
Rasmussen, A.J.3
Logsdon, C.D.4
Fischer, S.M.5
McArthur, M.J.6
Hursting, S.D.7
-
49
-
-
84882676636
-
AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation
-
e775 10.1038/cddis.2013.282
-
Jackstadt R., Jung P., Hermeking H., AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation. Cell Death & Disease 2013 4 e775 10.1038/cddis.2013.282
-
(2013)
Cell Death & Disease
, vol.4
-
-
Jackstadt, R.1
Jung, P.2
Hermeking, H.3
-
50
-
-
84887899719
-
Induction of beta-cell replication by a synthetic HNF4alpha antagonist
-
10.1002/stem.1496
-
Lee S. H., Piran R., Keinan E., Pinkerton A., Levine F., Induction of beta-cell replication by a synthetic HNF4alpha antagonist. Stem Cells 2013 31 11 2396 2407 10.1002/stem.1496
-
(2013)
Stem Cells
, vol.31
, Issue.11
, pp. 2396-2407
-
-
Lee, S.H.1
Piran, R.2
Keinan, E.3
Pinkerton, A.4
Levine, F.5
|