메뉴 건너뛰기




Volumn 7, Issue 5, 2014, Pages 1285-1290

Effect of metformin on the human T98G glioblastoma multiforme cell line

Author keywords

Apoptosis; Glioblastoma cell line; Metformin; T98G

Indexed keywords

3 (4, 5 DIMETHYL 2 THIAZOLYL) 2, 5 DIPHENYLTETRAZOLIUM BROMIDE; ACRIDINE ORANGE; CASPASE 3; DNA NUCLEOTIDYLEXOTRANSFERASE; ETHIDIUM BROMIDE; METFORMIN; UNCLASSIFIED DRUG;

EID: 84896838154     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2014.1597     Document Type: Article
Times cited : (11)

References (29)
  • 1
    • 35848943883 scopus 로고    scopus 로고
    • Metformin-life begins at 50: A symposium held on the occasion of the 43rd Annual Meeting of the European Association for the Study of Diabetes, Amsterdam, The Netherlands, September 2007. (Meeting Report)
    • Campbell IW: Metformin-life begins at 50: A symposium held on the occasion of the 43rd Annual Meeting of the European Association for the Study of Diabetes, Amsterdam, The Netherlands, September 2007. (Meeting Report). Br J Diabet Vasc Dis 7: 247-252, 2007.
    • (2007) Br J Diabet Vasc Dis , vol.7 , pp. 247-252
    • Campbell, I.W.1
  • 2
    • 84859043569 scopus 로고    scopus 로고
    • Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice
    • Li J, Deng J, Sheng W and Zuo Z: Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice. Pharmacol Biochem Behav 101: 564-574, 2012.
    • (2012) Pharmacol Biochem Behav , vol.101 , pp. 564-574
    • Li, J.1    Deng, J.2    Sheng, W.3    Zuo, Z.4
  • 3
    • 84862199583 scopus 로고    scopus 로고
    • Metformin-inclusive sulfonylurea therapy reduces the risk of Parkinson's disease occurring with Type2 diabetes in a Taiwanese population cohort
    • Wahlqvist ML, Lee MS, Hsu CC, Chuang SY, Lee JT and TsaiHN: Metformin-inclusive sulfonylurea therapy reduces the risk of Parkinson's disease occurring with Type2 diabetes in a Taiwanese population cohort. Parkinsonism Relat Disord 18: 753-758, 2012.
    • (2012) Parkinsonism Relat Disord , vol.18 , pp. 753-758
    • Wahlqvist, M.L.1    Lee, M.S.2    Hsu, C.C.3    Chuang, S.Y.4    Lee, J.T.5    Tsai, H.N.6
  • 4
    • 84255178432 scopus 로고    scopus 로고
    • Diabetes, cancer, and metformin: Connections of metabolism and cell proliferation
    • Gallagher EJ and LeRoith D: Diabetes, cancer, and metformin: connections of metabolism and cell proliferation. Ann NY Acad Sci 1243: 54-68, 2011.
    • (2011) Ann NY Acad Sci , vol.1243 , pp. 54-68
    • Gallagher, E.J.1    LeRoith, D.2
  • 5
    • 69549097703 scopus 로고    scopus 로고
    • New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
    • Libby G, Donnelly LA, Donnan PT, Alessi DR, Morris AD and Evans JM: New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care 32: 1620-1625, 2009.
    • (2009) Diabetes Care , vol.32 , pp. 1620-1625
    • Libby, G.1    Donnelly, L.A.2    Donnan, P.T.3    Alessi, D.R.4    Morris, A.D.5    Evans, J.M.6
  • 7
    • 79955980904 scopus 로고    scopus 로고
    • Metformin induces both caspase-dependent and poly(ADP-ribose) polymerase-dependent cell death in breast cancer cells
    • Zhuang Y and Miskimins WK: Metformin induces both caspase-dependent and poly(ADP-ribose) polymerase-dependent cell death in breast cancer cells. Mol Cancer Res 9: 603-615, 2011.
    • (2011) Mol Cancer Res , vol.9 , pp. 603-615
    • Zhuang, Y.1    Miskimins, W.K.2
  • 8
    • 84863006773 scopus 로고    scopus 로고
    • Metformin: Direct inhibition of rat ovarian theca-interstitial cell proliferation
    • Will MA, Palaniappan M, Peegel H, Kayampilly P and MenonKM: Metformin: direct inhibition of rat ovarian theca-interstitial cell proliferation. Fertil Steril 98: 207-214, 2012.
    • (2012) Fertil Steril , vol.98 , pp. 207-214
    • Will, M.A.1    Palaniappan, M.2    Peegel, H.3    Kayampilly, P.4    Menon, K.M.5
  • 10
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-MelodyJ, etal: Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108: 1167-1174, 2001.
    • (2001) J Clin Invest , vol.108 , pp. 1167-1174
    • Zhou, G.1    Myers, R.2    Li, Y.3    Chen, Y.4    Shen, X.5    Fenyk-Melody, J.6
  • 13
    • 58149354390 scopus 로고    scopus 로고
    • Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1
    • Zhuang Y and Miskimins WK: Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1. J Mol Signal 3: 18, 2008.
    • (2008) J Mol Signal , vol.3 , pp. 18
    • Zhuang, Y.1    Miskimins, W.K.2
  • 14
    • 33750717843 scopus 로고    scopus 로고
    • Current therapeutic approaches in patients with brain metastases
    • Peacock KH and Lesser GJ: Current therapeutic approaches in patients with brain metastases. Curr Treat Options Oncol 7: 479-489, 2006.
    • (2006) Curr Treat Options Oncol , vol.7 , pp. 479-489
    • Peacock, K.H.1    Lesser, G.J.2
  • 16
    • 77954341696 scopus 로고    scopus 로고
    • Survival signalling and apoptosis resistance in glioblastomas: Opportunities for targeted therapeutics
    • Krakstad C and Chekenya M: Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics. Mol Cancer 9: 135, 2010.
    • (2010) Mol Cancer , vol.9 , pp. 135
    • Krakstad, C.1    Chekenya, M.2
  • 17
    • 79551493930 scopus 로고    scopus 로고
    • Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide
    • Łabuzek K, Suchy D, Gabryel B, Bielecka A, Liber S and Okopień B: Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide. Pharmacol Rep 62: 956-965, 2010.
    • (2010) Pharmacol Rep , vol.62 , pp. 956-965
    • Łabuzek, K.1    Suchy, D.2    Gabryel, B.3    Bielecka, A.4    Liber, S.5    Okopień, B.6
  • 19
    • 0023619677 scopus 로고
    • A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity
    • Twentyman PR and Luscombe M: A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity. Br J Cancer 56: 279-285, 1987.
    • (1987) Br J Cancer , vol.56 , pp. 279-285
    • Twentyman, P.R.1    Luscombe, M.2
  • 21
    • 77952116629 scopus 로고    scopus 로고
    • Metformin in cancer therapy: A new perspective for an old antidiabetic drug?
    • Ben Sahra I, Le Marchand-Brustel Y, Tanti JF and Bost F: Metformin in cancer therapy: a new perspective for an old antidiabetic drug? Mol Cancer Ther 9: 1092-1099, 2010.
    • (2010) Mol Cancer Ther , vol.9 , pp. 1092-1099
    • Ben Sahra, I.1    Le Marchand-Brustel, Y.2    Tanti, J.F.3    Bost, F.4
  • 23
    • 79955490053 scopus 로고    scopus 로고
    • Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types
    • Iliopoulos D, Hirsch HA and Struhl K: Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types. Cancer Res 71: 3196-3201, 2010.
    • (2010) Cancer Res , vol.71 , pp. 3196-3201
    • Iliopoulos, D.1    Hirsch, H.A.2    Struhl, K.3
  • 24
    • 78650677585 scopus 로고    scopus 로고
    • Metformin reduces cisplatin-mediated apoptotic death of cancer cells through AMPK-independent activation of AKT
    • Janjetovic K, Vucicevic L, Misirkic M, VilimanovichU, TovilovicG, Zogovic N, etal: Metformin reduces cisplatin-mediated apoptotic death of cancer cells through AMPK-independent activation of AKT. Eur J Pharmacol 651: 41-50, 2011.
    • (2011) Eur J Pharmacol , vol.651 , pp. 41-50
    • Janjetovic, K.1    Vucicevic, L.2    Misirkic, M.3    Vilimanovich, U.4    Tovilovic, G.5    Zogovic, N.6
  • 25
    • 79955834631 scopus 로고    scopus 로고
    • Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity invivo
    • Rattan R, Graham RP, Maguire JL, Giri S and Shridhar V: Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity invivo. Neoplasia 13: 483-491, 2011.
    • (2011) Neoplasia , vol.13 , pp. 483-491
    • Rattan, R.1    Graham, R.P.2    Maguire, J.L.3    Giri, S.4    Shridhar, V.5
  • 28
    • 77954341696 scopus 로고    scopus 로고
    • Survival signalling and apoptosis resistance in glioblastomas: Opportunities for targeted therapeutics
    • Kraskstad C and Chekenya M: Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics. Mol Cancer 9: 135, 2010.
    • (2010) Mol Cancer , vol.9 , pp. 135
    • Kraskstad, C.1    Chekenya, M.2
  • 29
    • 84862934329 scopus 로고    scopus 로고
    • Deregulated signaling pathways in glioblastoma multiforme: Molecular mechanisms and therapeutic targets
    • Mao H, Lebrun DG, Yang J, Zhu VF and Li M: Deregulated signaling pathways in glioblastoma multiforme: molecular mechanisms and therapeutic targets. Cancer Invest 30: 48-56, 2012.
    • (2012) Cancer Invest , vol.30 , pp. 48-56
    • Mao, H.1    Lebrun, D.G.2    Yang, J.3    Zhu, V.F.4    Li, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.