Metformin: Direct inhibition of rat ovarian theca-interstitial cell proliferation

Fertility and Sterility

Volumn 98, Issue 1, 2012, Pages 207-214

  Will, Matthew A ^a   Palaniappan, Murugesan ^a   Peegel, Helle ^a   Kayampilly, Pradeep ^a   Menon, K M J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

AMPK; insulin; metformin; PCOS; proliferation; theca interstitial cell

Indexed keywords

ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE; ADENOSINE PHOSPHATE; CYCLIN D3; CYCLIN DEPENDENT KINASE 4; INSULIN; METFORMIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE PROGRESSION; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; EXPERIMENTAL STUDY; FEMALE; IN VITRO STUDY; LEYDIG CELL; NONHUMAN; OVARIAN THECA INTERSTITIAL CELL; OVARY CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION; WESTERN BLOTTING;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; FEMALE; HYPOGLYCEMIC AGENTS; MAP KINASE SIGNALING SYSTEM; METFORMIN; OVARY; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES; THECA CELLS;

EID: 84863006773     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2012.04.010     Document Type: Article

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