Interactions between mesenchymal stem cells, adipocytes, and osteoblasts in a 3D tri-culture model of hyperglycemic conditions in the bone marrow microenvironment

Integrative Biology (United Kingdom)

Volumn 6, Issue 3, 2014, Pages 324-337

  Rinker, Torri E ^a   Hammoudi, Taymour M ^a   Kemp, Melissa L ^a   Lu, Hang ^b   Temenoff, Johnna S ^a  

^a Emory University   (United States)

^b Georgia Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

ADIPOCYTE; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL INTERACTION; CELL TYPE; CELL VIABILITY; CLONOGENESIS; COCULTURE; COLONY FORMING UNIT; CONTROLLED STUDY; GENE EXPRESSION; HISTOCHEMISTRY; HUMAN; HUMAN CELL; HYDROGEL; HYPERGLYCEMIA; MESENCHYMAL STEM CELL; MICROENVIRONMENT; OSTEOBLAST; PRIORITY JOURNAL;

ADIPOCYTES; ADIPOGENESIS; ALKALINE PHOSPHATASE; BONE MARROW; CELL COMMUNICATION; CELL SURVIVAL; CELLS, CULTURED; CELLULAR MICROENVIRONMENT; COCULTURE TECHNIQUES; ENERGY METABOLISM; GENE EXPRESSION; GLUCOSE; HUMANS; HYDROGELS; HYPERGLYCEMIA; MESENCHYMAL STROMAL CELLS; MODELS, BIOLOGICAL; MULTIVARIATE ANALYSIS; OSTEOBLASTS; OSTEOPOROSIS; PHENOTYPE; STEM CELL NICHE;

EID: 84896827685     PISSN: 17579694     EISSN: 17579708     Source Type: Journal    
DOI: 10.1039/c3ib40194d     Document Type: Article

References (46)

1. F. J. A. de Paula M. C. Horowitz C. J. Rosen Novel insights into the relationship between diabetes and osteoporosis Diabetes/Metab. Res. Rev. 2010 26 622 630
2. G. Mazziotti J. Bilezikian E. Canalis D. Cocchi A. Giustina New understanding and treatments for osteoporosis Endocrine 2012 41 58 69
3. C. J. Rosen M. L. Bouxsein Mechanisms of disease: is osteoporosis the obesity of bone? Nat. Clin. Pract. Rheumatol. 2006 2 35 43 (Pubitemid 43153647)
4. A. Giaccari G. Sorice G. Muscogiuri Glucose toxicity: the leading actor in the pathogenesis and clinical history of type 2 diabetes-mechanisms and potentials for treatment Nutr., Metab. Cardiovasc. Dis. 2009 19 365 377
5. D. L. Jones A. J. Wagers No place like home: anatomy and function of the stem cell niche Nat. Rev. Mol. Cell Biol. 2008 9 11 21
6. J. J. Minguell A. Erices P. Conget P. A. C. Onget Mesenchymal Stem Cells Exp. Biol. Med. 2001 226 507 520 (Pubitemid 32524497)
7. N. Z. Kuhn R. S. Tuan Regulation of stemness and stem cell niche of mesenchymal stem cells: implications in tumorigenesis and metastasis J. Cell. Physiol. 2010 222 268 277
8. S. Lecourt V. Vanneaux A. Cras D. Freida D. Heraoui L. Herbi C. Caillaud C. Chomienne J. P. Marolleau N. Belmatoug J. Larghero Bone marrow microenvironment in an in vitro model of Gaucher disease: consequences of glucocerebrosidase deficiency Stem Cells Dev. 2012 21 239 248
9. C. Cramer E. Freisinger R. K. Jones D. P. Slakey C. L. Dupin E. R. Newsome E. U. Alt R. Izadpanah Persistent high glucose concentrations alter the regenerative potential of mesenchymal stem cells Stem Cells Dev. 2010 19 1875 1884
10. V. Gopalakrishnan R. C. Vignesh J. Arunakaran M. M. Aruldhas N. Srinivasan Effects of glucose and its modulation by insulin and estradiol on BMSC differentiation into osteoblastic lineages Biochem. Cell Biol. 2006 84 93 101
11. Y. Li T. Schilling P. Benisch S. Zeck J. Meissner-Weigl D. Schneider C. Limbert J. Seufert M. Kassem N. Schütze F. Jakob R. Ebert Effects of high glucose on mesenchymal stem cell proliferation and differentiation Biochem. Biophys. Res. Commun. 2007 363 209 215 (Pubitemid 47430115)
12. A. Stolzing N. Coleman A. Scutt Glucose-induced replicative senescence in mesenchymal stem cells Rejuvenation Res. 2006 9 31 35
13. A. Gagnon A. Sorisky The effect of glucose concentration on insulin-induced 3T3-L1 adipose cell differentiation Obes. Res. 1998 6 157 163 (Pubitemid 128679657)
14. Y. Lin A. H. Berg P. Iyengar T. K. T. Lam A. Giacca T. P. Combs M. W. Rajala X. Du B. Rollman W. Li M. Hawkins N. Barzilai C. J. Rhodes I. G. Fantus M. Brownlee P. E. Scherer The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species J. Biol. Chem. 2005 280 4617 4626 (Pubitemid 40288630)
15. J. Sun Y. Xu Z. Dai Y. Sun Intermittent high glucose stimulate MCP-l, IL-18, and PAI-1, but inhibit adiponectin expression and secretion in adipocytes dependent of ROS Cell Biochem. Biophys. 2009 55 173 180
16. S. Botolin L. R. McCabe Chronic hyperglycemia modulates osteoblast gene expression through osmotic and non-osmotic pathways J. Cell. Biochem. 2006 99 411 424 (Pubitemid 44435559)
17. A. García-Hernández H. Arzate I. Gil-Chavarría R. Rojo L. Moreno-Fierros High glucose concentrations alter the biomineralization process in human osteoblastic cells Bone 2012 50 276 288
18. M. Inaba Y. Nishizawa A. Shioi H. Morii Importance of sustained high glucose condition in the development of diabetic osteopenia: Possible involvement of the polyol pathway Osteoporosis Int. 1997 7 209 212 (Pubitemid 28014192)
19. M. Zayzafoon C. Stell R. Irwin L. R. McCabe Extracellular Glucose Influences Osteoblast Differentiation and c-Jun Expression J. Cell. Biochem. 2000 79 301 310
20. L. M. Coe R. Irwin D. Lippner L. R. McCabe The bone marrow microenvironment contributes to type I diabetes induced osteoblast death J. Cell Physiol. 2011 226 477 483
21. R. Nakaoka S. X. Hsiong D. J. Mooney Regulation of chondrocyte differentiation level via co-culture with osteoblasts Tissue Eng. 2006 12 2425 2433 (Pubitemid 46141266)
22. Y. Tsuda A. Kikuchi M. Yamato G. Chen T. Okano Heterotypic cell interactions on a dually patterned surface Biochem. Biophys. Res. Commun. 2006 348 937 944 (Pubitemid 44233506)
23. J. Lee M. J. Cuddihy N. A. Kotov Three-dimensional cell culture matrices: state of the art Tissue Eng., Part B 2008 14 61 86
24. L. Leng A. McAllister B. Zhang M. Radisic A. Günther Mosaic hydrogels: one-step formation of multiscale soft materials Adv. Mater. 2012 24 3650 3658
25. T. M. Hammoudi C. A. Rivet M. L. Kemp H. Lu J. S. Temenoff Three-dimensional in vitro tri-culture platform to investigate effects of crosstalk between mesenchymal stem cells, osteoblasts, and adipocytes Tissue Eng., Part A 2012 18 1686 1697
26. S. K. Hamilton N. C. Bloodworth C. S. Massad T. M. Hammoudi S. Suri P. J. Yang H. Lu J. S. Temenoff Development of 3D hydrogel culture systems with on-demand cell separation Biotechnol. J. 2013 8 485 495
27. J. Patterson J. A. Hubbell Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2 Biomaterials 2010 31 7836 7845
28. P. J. Yang M. E. Levenston J. S. Temenoff Modulation of mesenchymal stem cell shape in enzyme-sensitive hydrogels is decoupled from upregulation of fibroblast markers under cyclic tension Tissue Eng., Part A 2012 18 2365 2375
29. B. D. Cosgrove L. G. Griffith D. A. Lauffenburger Fusing tissue engineering and systems biology toward fulfilling their promise Cell. Mol. Bioeng. 2008 1 33 41
30. D. C. Kirouac C. Ito E. Csaszar A. Roch M. Yu E. A. Sykes G. D. Bader P. W. Zandstra Dynamic interaction networks in a hierarchically organized tissue Mol. Syst. Biol. 2010 6 417
31. C. A. Rivet A. S. Hill H. Lu M. L. Kemp Predicting cytotoxic T-cell age from multivariate analysis of static and dynamic biomarkers Mol. Cell. Proteomics 2011 10 M110.003921
32. S. Gaudet K. A. Janes J. G. Albeck E. A. Pace D. A. Lauffenburger P. K. Sorger A compendium of signals and responses triggered by prodeath and prosurvival cytokines Mol. Cell. Proteomics 2005 4 1569 1590 (Pubitemid 41555481)
33. S. Wasnik, A. Tiwari, M. A. Kirkland and G. Pande, in International review of cell and molecular biology, ed., K. W. Jeon, Academic Press, 1st edn, 2012, ch. 3, vol. 298, pp. 95-133
34. G. S. Travlos Normal structure, function, and histology of the bone marrow Toxicol. Pathol. 2006 34 548 565 (Pubitemid 44652217)
35. S. C. Manolagas Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis Endocr. Rev. 2000 21 115 137 (Pubitemid 32275592)
36. E. J. Sheehy T. Vinardell C. T. Buckley D. J. Kelly Engineering osteochondral constructs through spatial regulation of endochondral ossification Acta Biomater. 2013 9 5484 5492
37. K. Cusi The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes Curr. Diabetes Rep. 2010 10 306 315
38. A. I. Caplan Adult mesenchymal stem cells for tissue engineering versus regenerative medicine J. Cell. Physiol. 2007 213 341 347 (Pubitemid 47509711)
39. P. K. Fazeli M. C. Horowitz O. A. MacDougald E. L. Scheller M. S. Rodeheffer C. J. Rosen A. Klibanski Marrow fat and bone - new perspectives J. Clin. Endocrinol. Metab. 2013 98 935 945
40. M. A. Bredella P. K. Fazeli K. K. Miller M. Misra M. Torriani B. J. Thomas R. H. Ghomi C. J. Rosen A. Klibanski Increased bone marrow fat in anorexia nervosa J. Clin. Endocrinol. Metab. 2009 94 2129 2136
41. J. F. Griffith D. K. Yeung H. T. Ma J. C. Leung T. C. Kwok P. C. Leung Bone marrow fat content in the elderly: a reversal of sex difference seen in younger subjects J. Magn. Reson. Imaging 2012 36 225 230
42. M. S. Hahn L. J. Taite J. J. Moon M. C. Rowland K. A. Ruffino J. L. West Photolithographic patterning of polyethylene glycol hydrogels Biomaterials 2006 27 2519 2524 (Pubitemid 43113276)
43. J. J. Moon J. E. Saik R. A. Poche J. E. Leslie-barbick A. A. Smith M. E. Dickinson J. L. West R. a. Poché S.-H. Lee Biomimetic hydrogels with pro-angiogenic properties Biomaterials 2010 31 3840 3847
44. J. S. Temenoff K. A. Athanasiou R. G. LeBaron A. G. Mikos Effect of poly(ethylene glycol) molecular weight on tensile and swelling properties of oligo(poly(ethylene glycol) fumarate) hydrogels for cartilage tissue engineering J. Biomed. Mater. Res. 2002 59 429 437 (Pubitemid 34037486)
45. L. Eriksson, E. Johansson, N. Kettaneh-Wold, J. Trygg, C. Wikstrom and S. Wold, Multi- and Megavariate Data Analysis Part I: Basic Principles and Applications, Umetrics AB, Umea, Sweden, 2nd edn, 2006
46. L. Eriksson, E. Johansson, N. Kettaneh-Wold, J. Trygg, C. Wikstrom and S. Wold, Multi- and Megavariate Data Analysis Part II: Advanced Applications and Method Extensions, Umetrics, Umea, Sweden, 2nd edn, 2006