Intermittent High Glucose Stimulate MCP-l, IL-18, and PAI-1, but Inhibit Adiponectin Expression and Secretion in Adipocytes Dependent of ROS

Cell Biochemistry and Biophysics

Volumn 55, Issue 3, 2009, Pages 173-180

  Sun, Jiazhong ^a   Xu, Yancheng ^a   Dai, Zhe ^a   Sun, Yanlei ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Adipokines; Intermittent high glucose; ROS

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8-HYDROXY-2'-DEOXYGUANOSINE; ADIPONECTIN; DEOXYGUANOSINE; DRUG DERIVATIVE; GLUCOSE; INTERLEUKIN 18; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; REACTIVE OXYGEN METABOLITE;

ADIPOCYTE; ANIMAL; ARTICLE; CELL STRAIN 3T3; DRUG EFFECT; GENETICS; METABOLISM; MOUSE; SECRETION;

3T3-L1 CELLS; ADIPOCYTES; ADIPONECTIN; ANIMALS; CHEMOKINE CCL2; DEOXYGUANOSINE; GLUCOSE; INTERLEUKIN-18; MICE; PLASMINOGEN ACTIVATOR INHIBITOR 1; REACTIVE OXYGEN SPECIES;

EID: 73349092158     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-009-9066-3     Document Type: Article

References (43)

1. Kannel, W. B., & McGee, D. L. (1979). Diabetes and cardiovascular diseases. The Framin-gham study. JAMA, 241, 2035-2038.
2. Aronson, D. (2008). Hyperglycemia and the pathobiology of diabetic complications. Advances in Cardiology, 45, 1-16.
3. Brownlee, M. (2001). Biochemistry and molecular cell biology of diabetic complications. Nature, 414, 813-820.
4. Hotamisligil, G. S. (2003). Inflammatory pathways and insulin action. International Journal of Obesity and Related Metabolic Disorders, 27(Suppl 3), S53-S55.
5. Yudkin, J. S. (2003). Adipose tissue, insulin action and vascular disease: Inflammatory signals. International Journal of Obesity and Related Metabolic Disorders, 27(Suppl 3), S25-S28.
6. Fantuzzi, (2005). Adipose tissue, adipokines, and inflammation. The Journal of Allergy and Clinical Immunology, 115, 911-919.
7. Trayhurn, P., & Wood, I. S. (2004). Adipokines: Inflammation and the pleiotropic role of white adipose tissue. British Journal of Nutrition, 92, 347-355.
8. Lam, K. S., & Xu, A. (2005). Adiponectin: Protection of the endothelium. Current Diabetes Reports, 5, 254-259.
9. Lin, Y., Berg, A. H., Iyengar, P., Lam, T. K., Giacca, A., Combs, T. P., et al. (2005). The hyperglycemia-induced inflammatory response in adipocytes: The role of reactive oxygen species. Journal of Biological Chemistry, 280, 4617-4626.
10. Kamigaki, M., Sakaue, S., Tsujino, I., Ohira, H., Ikeda, D., Itoh, N., et al. (2006). Oxidative stress provokes atherogenic changes in adipokine gene expression in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications, 339, 624-632.
11. Kasai, H., Crain, P. F., Kuchino, Y., Nishimura, S., Ootsuyama, A., & Tanooka, H. (1986). Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis, 7, 1849-1851.
12. Park, K. S., Kim, J. H., Kim, M. S., Kim, J. M., Kim, S. K., Choi, J. Y., et al. (2001). Effects of insulin and antioxidant on plasma 8-hydroxyguanine and tissue 8-hydroxydeoxygu- anosine in streptozotocin-induced diabetic rats. Diabetes, 50, 2837-2841.
13. Hirata, T., Unoki, H., Bujo, H., Ueno, K., & Saito, Y. (2006). Activation of diacylglycerol O-acyltransferase 1 gene results in increased tumor necrosis factor-alpha gene expression in 3T3-L1 adipocytes. FEBS Letters, 580, 5117-5121.
14. Negre-Salvayre, A., Auge, N., Duval, C., Robbesyn, F., Thiers, J. C., Nazzal, D., et al. (2002). Detection of intracellular reactive oxygen species in cultured cells using fluorescent probes. Methods in Enzymology, 352, 62-71.
15. Quagliaro, L., Piconi, L., Assaloni, R., Martinelli, L., Motz, E., & Ceriello, A. (2003). Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: The role of protein kinase C and NAD(P)H-oxidase activation. Diabetes, 52, 2795-2804.
16. Livak, K. J., & Schmittgen, T. D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods, 25, 402-408.
17. Shuldiner, A. R., Yang, R., & Gong, D. W. (2001). Resistin, obesity and insulin resistance-the emerging role of the adipocyte as an endocrine organ. New England Journal of Medicine, 345(18), 1345-1346.
18. Mori, E., Komori, K., Yamaoka, T., Tanii, M., Kataoka, C., Takeshita, A., et al. (2002). Essential role of monocyte chemoattractant protein-1 in development of restenotic changes (neointimal hyperplasia and constrictive remodeling) after balloon angioplasty in hypercholesterolemic rabbits. Circulation, 105, 2905-2910.
19. Namiki, M., Kawashima, S., Yamashita, T., Ozaki, M., Hirase, T., Ishida, T., et al. (2002). Local overexpression of monocyte chemoattractant protein1 at vessel wall induces infiltration of macrophages and formation of atherosclerotic lesion: Synergism with hypercholesterolemia. Arteriosclerosis, Thrombosis, and Vascular Biology, 22(1), 115-120.
20. Christiansen, T., Richelsen, B., & Bruun, J. M. (2005). Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbid obese subjects. International Journal of Obesity and Related Metabolic Disorders, 29, 146-150.
21. Escobar-Morreale, H. F., Botella-Carretero, J. I., Villuendas, G., Sancho, J., & San Millán, J. L. (2004). Serum interleukin-18 concentrations are increased in the polycystic ovary syndrome: Relationship to insulin resistance and to obesity. Journal of Clinical Endocrinology and Metabolism, 89(80), 6-811.
22. Esposito, K., Pontillo, A., Di Palo, C., Giugliano, G., Masella, M., Marfella, R., et al. (2003). Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: A randomized trial. JAMA, 289(14), 1799-1804.
23. Park, C. C., Morel, J. C., Amin, M. A., Connors, M. A., Harlow, L. A., & Koch, A. E. (2001). Evidence of IL-18 as a novel angiogenic mediator. Journal of Immunology, 167(3), 1644-1653.
24. Landin, K., Stigendal, L., Eriksson, E., Krotkiewski, M., Risberg, B., Tengborn, L., et al. (1990). Abdominal obesity is associated with an impaired fibrinolytic activity and elevated plasminogen activator inhibitor-1. Metabolism, 39(10), 1044-1048.
25. McGill, J. B., Schneider, D. J., Arfken, C. L., Lucore, C. L., & Sobel, B. E. (1994). Factors responsible for impaired fibrinolysis in obese subjects and NIDDM patients. Diabetes, 43, 104-109.
26. Hotta, K., Funahashi, T., Arita, Y., Takahashi, M., Matsuda, M., Okamoto, Y., et al. (2000). Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arteriosclerosis, Thrombosis, and Vascular Biology, 20(6), 1595-1599.
27. Tan, K. C., Xu, A., Chow, W. S., Lam, M. C., Ai, V. H., Tam, S. C., et al. (2004). Hypo- adiponectinemia is associated with impaired endothelium-dependent vasodilation. Journal of Clinical Endocrinology and Metabolism, 89(2), 765-769.
28. Ouchi, N., Kihara, S., Arita, Y., Maeda, K., Kuriyama, H., Okamoto, Y., et al. (1999). Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin. Circulation, 100(25), 2473-2476.
29. Ouchi, N., Kihara, S., Arita, Y., Nishida, M., Matsuyama, A., Okamoto, Y., et al. (2001). Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation, 103(8), 1057-1063.
30. Yokota, T., Oritani, K., Takahashi, I., Ishikawa, J., Matsuyama, A., Ouchi, N., et al. (2000). Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood, 96(5), 1723-1732.
31. Kita, A., Yamasaki, H., Kuwahara, H., Moriuchi, A., Fukushima, K., Kobayashi, M., et al. (2005). Identification of the promoter region required for human adiponectin gene transcription: Association with CCAAT/enhancer binding protein-beta and tumor necrosis factor-alpha. Biochemical and Biophysical Research Communications, 331(2), 484-490.
32. Bruun, J. M., Lihn, A. S., Verdich, C., Pedersen, S. B., Toubro, S., Astrup, A., et al. (2003). Regulation of adiponectin by adipose tissue-derived cytokines: In vivo and in vitro investigations in humans. American Journal of Physiology. Endocrinology and metabolism, 285(3), E527-E533.
33. Esposito, K., Nappo, F., Giugliano, F., Di Palo, C., Ciotola, M., Barbieri, M., et al. (2003). Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus. American Journal of Clinical Nutrition, 78(6), 1135-1140.
34. Todoric, J., Loffler, M., Huber, J., Bilban, M., Reimers, M., Kadl, A., et al. (2006). Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. Diabetologia, 49(9), 2109-2119.
35. Dandona, P., Alijada, A., Chaudhuri, A., Mohanty, P., & Garg, R. (2005). Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation, 111, 1448-1454.
36. Chen, B., Lam, K. S., Wang, Y., & Wu, D. (2006). Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes. Biochemical and Biophysical Research Communications, 341(2), 549-556.
37. Zherebitskaya, E., Akude, E., Smith, D. R., & Fernyhough, P. (2009). Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: Role of glucose-induced oxidative stress. Diabetes, 58(6), 1356-1364.
38. UK Prospective Diabetes Study (UKPDS) Group. (1998). Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet, 352, 837-853.
39. Ceriello, A. (2004). Impaired glucose tolerance and cardiovascular disease: the possible role of post-prandial hyperglycemia. American Heart Journal, 147, 803-807.
40. The Diabetes Control Complications Trial Research Group. (1993). The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. New England Journal of Medicine, 329, 977-986.
41. Singleton, J. R., Smith, A. G., Russell, J. W., & Feldman, E. L. (2003). Microvascular complications of impaired glucose tolerance. Diabetes, 52, 2867-2873.
42. Ceriello, A. (1998). The emerging role of post-prandial hyperglycaemic spikes in the pathogenesis of diabetic complications. Diabetic Medicine, 15, 188-193.
43. Lyon, C. J., & Hsueh, W. A. (2003). Effect of plasminogen activator inhibitor-1 in diabetes mellitus and cardiovascular disease. American Journal of Medicine, 115(Suppl 8A), 62S-68S.