Iron-catalyzed vinylogous aldol condensation of biginelli products and its application toward pyrido[4,3- d ]pyrimidinones

Journal of Organic Chemistry

Volumn 79, Issue 5, 2014, Pages 2281-2288

  Zhang, Lianqiang ^a   Zhang, Zhiguo ^a   Liu, Qingfeng ^a   Liu, Tongxin ^a   Zhang, Guisheng ^a  

^a HENAN NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOL CONDENSATION; AMIDE GROUPS; ARYL ALDEHYDES; BIGINELLI; ITS APPLICATIONS; PYRIMIDINE DERIVATIVES; SYNTHETIC PRECURSORS;

CATALYSIS; IRON COMPOUNDS;

CONDENSATION REACTIONS;

2 OXO N PHENYL 6 STYRYL 4 (THIOPHEN 2 YL) 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; 2 OXO N,4 DIPHENYL 6 [2 (THIOPHEN 2 YL)VINYL] 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; 2 OXO N,4 DIPHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; 4 (4 FLUOROPHENYL) 2 OXO N PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; 4 (4 FLUOROPHENYL) 6 (4 METHOXYSTYRYL) 2 OXO N PHENYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; 4 (4 FLUOROPHENYL) N (4 METHOXYPHENYL) 2 OXO 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; 4 (4 METHOXYPHENYL) 6 (4 METHOXYSTYRYL) 2 OXO N PHENYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; 6 [2 (FURAN 2 YL)VINYL] 2 OXO N,4 DIPHENYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; 6 ARYLVINYLDIHYDROPYRIMIDIN 2(1H) ONE DERIVATIVE; ALDEHYDE; AMIDE; DIHYDROPYRIMIDIN 2(1H) ONE DERIVATIVE; ETHYL 4 (2 OXO 4 PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDO)BEZOATE; IRON; ME THYL 4 [2 [6 (4 FL UOROPHENYL) 2 OXO 5 (PHENYLCARBAMOYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 4 YL]VINYL]BENZOATE; METHYL 4 [2 [2 OXO 6 PHENYL 5 (PHENYLCARBAMOYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 4 YL]VINYL]BENZOATE; METHYL 4 [2 [6 (4 FLUOROPHENYL) 2 OXO 5 (PHENYLCARBAMOYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 4 YL]VINYL]BENZOATE; METHYL 4 [2 [6 (4 METHOXYPHENYL) 2 OXO 5 (PHENYLCARBAMOYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 4 YL]VINYL]BENZOATE; N (2 CHLOROPHENYL) 2 OXO 4 PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; N (2 METHOXYPHENYL) 2 OXO 4 PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; N (3 CHLOROPHENYL) 2 OXO 4 PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; N (3 METHOXYPHENYL) 2 OXO 4 PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; N (4 CHLOROPHENYL) 2 OXO 4 PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; N (4 CHLOROPHENYL) 6 (4 METHOXYSTYRYL) 2 OXO 4 PHENYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; N (4 METHOXYPHENYL) 2 OXO PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; N BENZYL 2 OXO 4 PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; N METHYL 2 OXO 4 PHENYL 6 STYRYL 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; N,4 DIPHENYL 6 STYRYL 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXAMIDE; PYRIDO[4,3 D]PYRIMIDINONE DERIVATIVE; PYRIMIDINONE DERIVATIVE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; BIGINELLI REACTION; CATALYSIS; CHEMICAL REACTION; DRUG STRUCTURE;

CATALYSIS; IRON; MOLECULAR STRUCTURE; PYRIMIDINES; PYRIMIDINONES;

EID: 84896785761     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo402773r     Document Type: Article

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