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Volumn 124, Issue 3, 2014, Pages 1069-1082

Mutant p53.associated myosin-X upregulation promotes breast cancer invasion and metastasis

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MOLECULAR MOTOR; MUTANT PROTEIN; MYO10 PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 84896784204     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI67280     Document Type: Article
Times cited : (132)

References (68)
  • 2
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001;98(19):10869-10874.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.19 , pp. 10869-10874
    • Sorlie, T.1
  • 3
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, et al. Molecular portraits of human breast tumours. Nature. 2000;406(6797):747-752.
    • (2000) Nature , vol.406 , Issue.6797 , pp. 747-752
    • Perou, C.M.1
  • 4
    • 34547555607 scopus 로고    scopus 로고
    • Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
    • Naume B, et al. Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer. Mol Oncol. 2007;1(2):160-171.
    • (2007) Mol Oncol , vol.1 , Issue.2 , pp. 160-171
    • Naume, B.1
  • 5
    • 30844472903 scopus 로고    scopus 로고
    • The making of filopodia
    • Faix J, Rottner K. The making of filopodia. Curr Opin Cell Biol. 2006;18(1):18-25.
    • (2006) Curr Opin Cell Biol , vol.18 , Issue.1 , pp. 18-25
    • Faix, J.1    Rottner, K.2
  • 6
    • 44349179335 scopus 로고    scopus 로고
    • Filopodia: Molecular architecture and cellular functions
    • Mattila PK, Lappalainen P. Filopodia: molecular architecture and cellular functions. Nat Rev Mol Cell Biol. 2008;9(6):446-454.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.6 , pp. 446-454
    • Mattila, P.K.1    Lappalainen, P.2
  • 7
    • 80053444351 scopus 로고    scopus 로고
    • Filopodia and adhesion in cancer cell motility
    • Arjonen A, Kaukonen R, Ivaska J. Filopodia and adhesion in cancer cell motility. Cell Adh Migr. 2011; 5(5):421-430.
    • (2011) Cell Adh Migr , vol.5 , Issue.5 , pp. 421-430
    • Arjonen, A.1    Kaukonen, R.2    Ivaska, J.3
  • 8
    • 77951771838 scopus 로고    scopus 로고
    • Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia
    • Schoumacher M, Goldman RD, Louvard D, Vignjevic DM. Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia. J Cell Biol. 2010;189(3):541-556.
    • (2010) J Cell Biol , vol.189 , Issue.3 , pp. 541-556
    • Schoumacher, M.1    Goldman, R.D.2    Louvard, D.3    Vignjevic, D.M.4
  • 9
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • Minn AJ, et al. Genes that mediate breast cancer metastasis to lung. Nature. 2005;436(7050):518-524.
    • (2005) Nature , vol.436 , Issue.7050 , pp. 518-524
    • Minn, A.J.1
  • 11
    • 0037463236 scopus 로고    scopus 로고
    • Independent prognostic value of fascin immunoreactivity in stage i nonsmall cell lung cancer
    • Pelosi G, et al. Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer. Br J Cancer. 2003;88(4):537-547.
    • (2003) Br J Cancer , vol.88 , Issue.4 , pp. 537-547
    • Pelosi, G.1
  • 12
    • 11344285907 scopus 로고    scopus 로고
    • The expression of fascin, an actinbundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course
    • Yoder BJ, et al. The expression of fascin, an actinbundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course. Clin Cancer Res. 2005; 11(1):186-192.
    • (2005) Clin Cancer Res , vol.11 , Issue.1 , pp. 186-192
    • Yoder, B.J.1
  • 13
    • 84856777960 scopus 로고    scopus 로고
    • Myosin-X: A MyTH-FERM myosin at the tips of filopodia
    • Kerber ML, Cheney RE. Myosin-X: a MyTH-FERM myosin at the tips of filopodia. J Cell Sci. 2011; 124(pt 22):3733-3741.
    • (2011) J Cell Sci , vol.124 , Issue.PART 22 , pp. 3733-3741
    • Kerber, M.L.1    Cheney, R.E.2
  • 14
    • 0033766768 scopus 로고    scopus 로고
    • Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin
    • Berg JS, Derfler BH, Pennisi CM, Corey DP, Cheney RE. Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin. J Cell Sci. 2000;113(pt 19):3439-3451.
    • (2000) J Cell Sci , vol.113 , Issue.PART 19 , pp. 3439-3451
    • Berg, J.S.1    Derfler, B.H.2    Pennisi, C.M.3    Corey, D.P.4    Cheney, R.E.5
  • 15
    • 2942705683 scopus 로고    scopus 로고
    • Myosin-X provides a motor-based link between integrins and the cytoskeleton
    • Zhang H, et al. Myosin-X provides a motor-based link between integrins and the cytoskeleton. Nat Cell Biol. 2004;6(6):523-531.
    • (2004) Nat Cell Biol , vol.6 , Issue.6 , pp. 523-531
    • Zhang, H.1
  • 16
    • 0034630724 scopus 로고    scopus 로고
    • Mouse myosin X: Molecular architecture and tissue expression as revealed by northern blot and in situ hybridization analyses
    • Yonezawa S, et al. Mouse myosin X: molecular architecture and tissue expression as revealed by northern blot and in situ hybridization analyses. Biochem Biophys Res Commun. 2000;271(2):526-533.
    • (2000) Biochem Biophys Res Commun , vol.271 , Issue.2 , pp. 526-533
    • Yonezawa, S.1
  • 18
    • 34447130136 scopus 로고    scopus 로고
    • An inducible mouse model for skin cancer reveals distinct roles for gain-and loss-of-function p53 mutations
    • Caulin C, et al. An inducible mouse model for skin cancer reveals distinct roles for gain-and loss-of-function p53 mutations. J Clin Invest. 2007; 117(7):1893-1901.
    • (2007) J Clin Invest , vol.117 , Issue.7 , pp. 1893-1901
    • Caulin, C.1
  • 19
    • 72249100428 scopus 로고    scopus 로고
    • Mutant p53 drives invasion by promoting integrin recycling
    • Muller PA, et al. Mutant p53 drives invasion by promoting integrin recycling. Cell. 2009; 139(7):1327-1341.
    • (2009) Cell , vol.139 , Issue.7 , pp. 1327-1341
    • Muller, P.A.1
  • 20
    • 78951475020 scopus 로고    scopus 로고
    • P53 and its mutants in tumor cell migration and invasion
    • Muller PA, Vousden KH, Norman JC. p53 and its mutants in tumor cell migration and invasion. J Cell Biol. 2011;192(2):209-218.
    • (2011) J Cell Biol , vol.192 , Issue.2 , pp. 209-218
    • Muller, P.A.1    Vousden, K.H.2    Norman, J.C.3
  • 21
    • 44149121239 scopus 로고    scopus 로고
    • The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss
    • Terzian T, et al. The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss. Genes Dev. 2008;22(10):1337-1344.
    • (2008) Genes Dev , vol.22 , Issue.10 , pp. 1337-1344
    • Terzian, T.1
  • 22
    • 63049136592 scopus 로고    scopus 로고
    • A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
    • Adorno M, et al. A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell. 2009;137(1):87-98.
    • (2009) Cell , vol.137 , Issue.1 , pp. 87-98
    • Adorno, M.1
  • 23
    • 77951155224 scopus 로고    scopus 로고
    • Gain of oncogenic function of p53 mutants regulates E-cadherin expression uncoupled from cell invasion in colon cancer cells
    • Roger L, Jullien L, Gire V, Roux P. Gain of oncogenic function of p53 mutants regulates E-cadherin expression uncoupled from cell invasion in colon cancer cells. J Cell Sci. 2010;123(pt 8):1295-1305.
    • (2010) J Cell Sci , vol.123 , Issue.PART 8 , pp. 1295-1305
    • Roger, L.1    Jullien, L.2    Gire, V.3    Roux, P.4
  • 24
    • 79952049614 scopus 로고    scopus 로고
    • MiRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
    • Enerly E, et al. miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors. PLoS One. 2011;6(2):e16915.
    • (2011) PLoS One , vol.6 , Issue.2
    • Enerly, E.1
  • 25
    • 26444546442 scopus 로고    scopus 로고
    • An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
    • Miller LD, et al. An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci U S A. 2005;102(38):13550-13555.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.38 , pp. 13550-13555
    • Miller, L.D.1
  • 26
    • 79953060389 scopus 로고    scopus 로고
    • Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer
    • Vuoriluoto K, et al. Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer. Oncogene. 2011;30(12):1436-1448.
    • (2011) Oncogene , vol.30 , Issue.12 , pp. 1436-1448
    • Vuoriluoto, K.1
  • 27
    • 79955409333 scopus 로고    scopus 로고
    • Luminal and basallike breast cancer cells show increased migration induced by hypoxia, mediated by an autocrine mechanism
    • Voss MJ, Moller MF, Powe DG, Niggemann B, Zanker KS, Entschladen F. Luminal and basallike breast cancer cells show increased migration induced by hypoxia, mediated by an autocrine mechanism. BMC Cancer. 2011;11:158.
    • (2011) BMC Cancer , vol.11 , pp. 158
    • Voss, M.J.1    Moller, M.F.2    Powe, D.G.3    Niggemann, B.4    Zanker, K.S.5    Entschladen, F.6
  • 28
    • 0025129726 scopus 로고
    • Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
    • Soule HD, et al. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res. 1990;50(18):6075-6086.
    • (1990) Cancer Res , vol.50 , Issue.18 , pp. 6075-6086
    • Soule, H.D.1
  • 29
  • 30
    • 0028944308 scopus 로고
    • Identification of a novel anti-integrin monoclonal antibody that recognises a ligandinduced binding site epitope on the beta 1 subunit
    • Mould AP, Garratt AN, Askari JA, Akiyama SK, Humphries MJ. Identification of a novel anti-integrin monoclonal antibody that recognises a ligandinduced binding site epitope on the beta 1 subunit. FEBS Lett. 1995;363(1-2):118-122.
    • (1995) FEBS Lett , vol.363 , Issue.1-2 , pp. 118-122
    • Mould, A.P.1    Garratt, A.N.2    Askari, J.A.3    Akiyama, S.K.4    Humphries, M.J.5
  • 31
    • 0036039827 scopus 로고    scopus 로고
    • In vivo imaging of embryonic vascular development using transgenic zebrafish
    • Lawson ND, Weinstein BM. In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev Biol. 2002;248(2):307-318.
    • (2002) Dev Biol , vol.248 , Issue.2 , pp. 307-318
    • Lawson, N.D.1    Weinstein, B.M.2
  • 32
    • 73349090963 scopus 로고    scopus 로고
    • Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model
    • Lee SL, et al. Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model. Proc Natl Acad Sci U S A. 2009;106(46):19485-19490.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.46 , pp. 19485-19490
    • Lee, S.L.1
  • 33
    • 33846815517 scopus 로고    scopus 로고
    • Significance, detection and markers of disseminated breast cancer cells
    • Lacroix M. Significance, detection and markers of disseminated breast cancer cells. Endocr Relat Cancer. 2006;13(4):1033-1067.
    • (2006) Endocr Relat Cancer , vol.13 , Issue.4 , pp. 1033-1067
    • Lacroix, M.1
  • 34
    • 0032560027 scopus 로고    scopus 로고
    • P53 mutations isolated in yeast based on loss of transcription factor activity: Similarities and differences from p53 mutations detected in human tumors
    • Epstein CB, Attiyeh EF, Hobson DA, Silver AL, Broach JR, Levine AJ. p53 mutations isolated in yeast based on loss of transcription factor activity: similarities and differences from p53 mutations detected in human tumors. Oncogene. 1998; 16(16):2115-2122.
    • (1998) Oncogene , vol.16 , Issue.16 , pp. 2115-2122
    • Epstein, C.B.1    Attiyeh, E.F.2    Hobson, D.A.3    Silver, A.L.4    Broach, J.R.5    Levine, A.J.6
  • 35
    • 0033931447 scopus 로고    scopus 로고
    • The p53 tumor suppressor gene: From molecular biology to clinical investigation
    • Soussi T. The p53 tumor suppressor gene: from molecular biology to clinical investigation. Ann N Y Acad Sci. 2000;910:121-137.
    • (2000) Ann N y Acad Sci , vol.910 , pp. 121-137
    • Soussi, T.1
  • 36
    • 0028207349 scopus 로고
    • An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
    • Baas IO, Mulder JW, Offerhaus GJ, Vogelstein B, Hamilton SR. An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol. 1994;172(1):5-12.
    • (1994) J Pathol , vol.172 , Issue.1 , pp. 5-12
    • Baas, I.O.1    Mulder, J.W.2    Offerhaus, G.J.3    Vogelstein, B.4    Hamilton, S.R.5
  • 37
    • 79960410503 scopus 로고    scopus 로고
    • Merkel cell polyomavirus infection, large T antigen, retinoblastoma protein and outcome in Merkel cell carcinoma
    • Sihto H, Kukko H, Koljonen V, Sankila R, Bohling T, Joensuu H. Merkel cell polyomavirus infection, large T antigen, retinoblastoma protein and outcome in Merkel cell carcinoma. Clin Cancer Res. 2011;17(14):4806-4813.
    • (2011) Clin Cancer Res , vol.17 , Issue.14 , pp. 4806-4813
    • Sihto, H.1    Kukko, H.2    Koljonen, V.3    Sankila, R.4    Bohling, T.5    Joensuu, H.6
  • 38
    • 84880230412 scopus 로고    scopus 로고
    • Somatic mutation profiling and associations with prognosis and trastuzumab benefit in early breast cancer
    • Loi S, et al. Somatic mutation profiling and associations with prognosis and trastuzumab benefit in early breast cancer. J Natl Cancer Inst. 2013; 105(13):960-967.
    • (2013) J Natl Cancer Inst , vol.105 , Issue.13 , pp. 960-967
    • Loi, S.1
  • 39
    • 3342893272 scopus 로고    scopus 로고
    • Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion
    • Guo F, Zheng Y. Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion. Oncogene. 2004;23(33):5577-5585.
    • (2004) Oncogene , vol.23 , Issue.33 , pp. 5577-5585
    • Guo, F.1    Zheng, Y.2
  • 40
    • 76249108357 scopus 로고    scopus 로고
    • Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer
    • Morton JP, et al. Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer. Proc Natl Acad Sci U S A. 2010;107(1):246-251.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.1 , pp. 246-251
    • Morton, J.P.1
  • 41
    • 77955488036 scopus 로고    scopus 로고
    • LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest
    • Morton JP, et al. LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest. Gastroenterology. 2010;139(2):586-597.
    • (2010) Gastroenterology , vol.139 , Issue.2 , pp. 586-597
    • Morton, J.P.1
  • 42
    • 79953315567 scopus 로고    scopus 로고
    • Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis
    • Kennedy AL, et al. Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis. Mol Cell. 2011;42(1):36-49.
    • (2011) Mol Cell , vol.42 , Issue.1 , pp. 36-49
    • Kennedy, A.L.1
  • 43
    • 84874786083 scopus 로고    scopus 로고
    • Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion
    • Muller PA, et al. Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion. Oncogene. 2013;32(10):1252-1265.
    • (2013) Oncogene , vol.32 , Issue.10 , pp. 1252-1265
    • Muller, P.A.1
  • 44
    • 77952236403 scopus 로고    scopus 로고
    • Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells
    • Sauer L, Gitenay D, Vo C, Baron VT. Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells. Oncogene. 2010;29(18):2628-2637.
    • (2010) Oncogene , vol.29 , Issue.18 , pp. 2628-2637
    • Sauer, L.1    Gitenay, D.2    Vo, C.3    Baron, V.T.4
  • 45
    • 77957340300 scopus 로고    scopus 로고
    • The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cells
    • Cermak V, Kosla J, Plachy J, Trejbalova K, Hejnar J, Dvorak M. The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cells. Cell Mol Life Sci. 2010;67(20):3557-3568.
    • (2010) Cell Mol Life Sci , vol.67 , Issue.20 , pp. 3557-3568
    • Cermak, V.1    Kosla, J.2    Plachy, J.3    Trejbalova, K.4    Hejnar, J.5    Dvorak, M.6
  • 46
    • 8444221934 scopus 로고    scopus 로고
    • Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
    • Sasaki AT, Chun C, Takeda K, Firtel RA. Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J Cell Biol. 2004;167(3):505-518.
    • (2004) J Cell Biol , vol.167 , Issue.3 , pp. 505-518
    • Sasaki, A.T.1    Chun, C.2    Takeda, K.3    Firtel, R.A.4
  • 47
    • 35548932103 scopus 로고    scopus 로고
    • The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation
    • Tokuo H, Mabuchi K, Ikebe M. The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation. J Cell Biol. 2007;179(2):229-238.
    • (2007) J Cell Biol , vol.179 , Issue.2 , pp. 229-238
    • Tokuo, H.1    Mabuchi, K.2    Ikebe, M.3
  • 48
    • 77957874785 scopus 로고    scopus 로고
    • PtdIns(3,4,5)P is a regulator of myosin-X localization and filopodia formation
    • Plantard L, Arjonen A, Lock JG, Nurani G, Ivaska J, Stromblad S. PtdIns(3,4,5)P is a regulator of myosin-X localization and filopodia formation. J Cell Sci. 2010;123(pt 20):3525-3534.
    • (2010) J Cell Sci , vol.123 , Issue.PART 20 , pp. 3525-3534
    • Plantard, L.1    Arjonen, A.2    Lock, J.G.3    Nurani, G.4    Ivaska, J.5    Stromblad, S.6
  • 49
    • 0037415574 scopus 로고    scopus 로고
    • Mechanism of filopodia initiation by reorganization of a dendritic network
    • Svitkina TM, et al. Mechanism of filopodia initiation by reorganization of a dendritic network. J Cell Biol. 2003;160(3):409-421.
    • (2003) J Cell Biol , vol.160 , Issue.3 , pp. 409-421
    • Svitkina, T.M.1
  • 50
    • 47749098361 scopus 로고    scopus 로고
    • A myosin motor that selects bundled actin for motility
    • Nagy S, et al. A myosin motor that selects bundled actin for motility. Proc Natl Acad Sci U S A. 2008; 105(28):9616-9620.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.28 , pp. 9616-9620
    • Nagy, S.1
  • 51
    • 38049037417 scopus 로고    scopus 로고
    • Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors
    • Pi X, et al. Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors. J Cell Biol. 2007; 179(7):1569-1582.
    • (2007) J Cell Biol , vol.179 , Issue.7 , pp. 1569-1582
    • Pi, X.1
  • 52
    • 70349322724 scopus 로고    scopus 로고
    • Myosin-X is required for cranial neural crest cell migration in Xenopus laevis
    • Hwang YS, Luo T, Xu Y, Sargent TD. Myosin-X is required for cranial neural crest cell migration in Xenopus laevis. Dev Dyn. 2009;238(10):2522-2529.
    • (2009) Dev Dyn , vol.238 , Issue.10 , pp. 2522-2529
    • Hwang, Y.S.1    Luo, T.2    Xu, Y.3    Sargent, T.D.4
  • 53
    • 70349783561 scopus 로고    scopus 로고
    • Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells
    • Nie S, Kee Y, Bronner-Fraser M. Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells. Dev Biol. 2009;335(1):132-142.
    • (2009) Dev Biol , vol.335 , Issue.1 , pp. 132-142
    • Nie, S.1    Kee, Y.2    Bronner-Fraser, M.3
  • 54
    • 79960039752 scopus 로고    scopus 로고
    • A Pin1/mutant p53 axis promotes aggressiveness in breast cancer
    • Girardini JE, et al. A Pin1/mutant p53 axis promotes aggressiveness in breast cancer. Cancer Cell. 2011;20(1):79-91.
    • (2011) Cancer Cell , vol.20 , Issue.1 , pp. 79-91
    • Girardini, J.E.1
  • 55
    • 33750627650 scopus 로고    scopus 로고
    • Prognostic significance of fascin expression in advanced colorectal cancer: An immunohistochemical study of colorectal adenomas and adenocarcinomas
    • Hashimoto Y, Skacel M, Lavery IC, Mukherjee AL, Casey G, Adams JC. Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas. BMC Cancer. 2006;6:241.
    • (2006) BMC Cancer , vol.6 , pp. 241
    • Hashimoto, Y.1    Skacel, M.2    Lavery, I.C.3    Mukherjee, A.L.4    Casey, G.5    Adams, J.C.6
  • 56
    • 33645072444 scopus 로고    scopus 로고
    • Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas
    • Rodriguez-Pinilla SM, et al. Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas. Clin Cancer Res. 2006;12(5):1533-1539.
    • (2006) Clin Cancer Res , vol.12 , Issue.5 , pp. 1533-1539
    • Rodriguez-Pinilla, S.M.1
  • 57
  • 58
    • 79960915663 scopus 로고    scopus 로고
    • Mechanism and specificity of pentachloropseudilin-mediated inhibition of myosin motor activity
    • Chinthalapudi K, et al. Mechanism and specificity of pentachloropseudilin-mediated inhibition of myosin motor activity. J Biol Chem. 2011; 286(34):29700-29708.
    • (2011) J Biol Chem , vol.286 , Issue.34 , pp. 29700-29708
    • Chinthalapudi, K.1
  • 59
    • 58149251895 scopus 로고    scopus 로고
    • The mechanism of pentabromopseudilin inhibition of myosin motor activity
    • Fedorov R, et al. The mechanism of pentabromopseudilin inhibition of myosin motor activity. Nat Struct Mol Biol. 2009;16(1):80-88.
    • (2009) Nat Struct Mol Biol , vol.16 , Issue.1 , pp. 80-88
    • Fedorov, R.1
  • 60
    • 0031447171 scopus 로고    scopus 로고
    • Thermodynamic stability of wild-type and mutant p53 core domain
    • Bullock AN, et al. Thermodynamic stability of wild-type and mutant p53 core domain. Proc Natl Acad Sci U S A. 1997;94(26):14338-14342.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.26 , pp. 14338-14342
    • Bullock, A.N.1
  • 61
    • 46749123531 scopus 로고    scopus 로고
    • Egr-1 regulates expression of the glial scar component phosphacan in astrocytes after experimental stroke
    • Beck H, Semisch M, Culmsee C, Plesnila N, Hatzopoulos AK. Egr-1 regulates expression of the glial scar component phosphacan in astrocytes after experimental stroke. Am J Pathol. 2008;173(1):77-92.
    • (2008) Am J Pathol , vol.173 , Issue.1 , pp. 77-92
    • Beck, H.1    Semisch, M.2    Culmsee, C.3    Plesnila, N.4    Hatzopoulos, A.K.5
  • 62
    • 84858295593 scopus 로고    scopus 로고
    • Distinct recycling of active and inactive β1 integrins
    • Arjonen A, Alanko J, Veltel S, Ivaska J. Distinct recycling of active and inactive β1 integrins. Traffic. 2012;13(4):610-625.
    • (2012) Traffic , vol.13 , Issue.4 , pp. 610-625
    • Arjonen, A.1    Alanko, J.2    Veltel, S.3    Ivaska, J.4
  • 63
    • 33747447033 scopus 로고    scopus 로고
    • Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of β1-integrins
    • Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J. Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of β1-integrins. J Cell Biol. 2006;173(5):767-780.
    • (2006) J Cell Biol , vol.173 , Issue.5 , pp. 767-780
    • Pellinen, T.1    Arjonen, A.2    Vuoriluoto, K.3    Kallio, K.4    Fransen, J.A.5    Ivaska, J.6
  • 64
    • 84864870872 scopus 로고    scopus 로고
    • Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo
    • Högnäs G, et al. Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo. Oncogene. 2012;31(31):3597-3606.
    • (2012) Oncogene , vol.31 , Issue.31 , pp. 3597-3606
    • Högnäs, G.1
  • 66
    • 0037341394 scopus 로고    scopus 로고
    • Amplification of erbB2 and erbB2 expression are superior to estrogen receptor status as risk factors for distant recurrence in pT1N0M0 breast cancer: A nationwide population-based study
    • Joensuu H, et al. Amplification of erbB2 and erbB2 expression are superior to estrogen receptor status as risk factors for distant recurrence in pT1N0M0 breast cancer: a nationwide population-based study. Clin Cancer Res. 2003;9(3):923-930.
    • (2003) Clin Cancer Res , vol.9 , Issue.3 , pp. 923-930
    • Joensuu, H.1
  • 67
    • 48249101964 scopus 로고    scopus 로고
    • Molecular subtypes of breast cancers detected in mammography screening and outside of screening
    • Sihto H, et al. Molecular subtypes of breast cancers detected in mammography screening and outside of screening. Clin Cancer Res. 2008;14(13):4103-4110.
    • (2008) Clin Cancer Res , vol.14 , Issue.13 , pp. 4103-4110
    • Sihto, H.1
  • 68
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 2002;30(1):207-210.
    • (2002) Nucleic Acids Res , vol.30 , Issue.1 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.