Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin

Journal of Cell Science

Volumn 113, Issue 19, 2000, Pages 3439-3451

  Berg, J S ^a   Derfler, B H ^a   Pennisi, C M ^a   Corey, D P ^a   Cheney, R E ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

MYO10; Myosin X; Pleckstrin homology domain; Unconventional myosin

Indexed keywords

ACTIN; COMPLEMENTARY DNA; ERYTHROCYTE BAND 4.1 PROTEIN; EZRIN; KINESIN; MOESIN; MYOSIN; MYOSIN X; PHOSPHATIDYLINOSITOL; PHOSPHOLIPID; PLECKSTRIN; RADIXIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATTLE; CELL CULTURE; CELL MEMBRANE; CELL STRAIN; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA SEQUENCE; DOG; HUMAN; KIDNEY CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE;

ACTINS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BLOOD PROTEINS; BLOTTING, NORTHERN; CALPAIN; CATTLE; CELL FRACTIONATION; CELL LINE; CELL MEMBRANE STRUCTURES; CONSERVED SEQUENCE; CYTOCHALASIN D; DNA, COMPLEMENTARY; HUMANS; IN SITU HYBRIDIZATION; KIDNEY; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MYOSINS; PHOSPHOPROTEINS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; SEQUENCE ALIGNMENT;

ANIMALIA; BOS TAURUS; BOVINAE; CANIS FAMILIARIS; MAMMALIA;

EID: 0033766768     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. The Src homology domain 3 (SH3) of a yeast type I myosin, Myo5p, binds to verprolin and is required for targeting to sites of actin polarization
2. A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages
3. Are class III and class IX myosins motorized signalling molecules?
4. Myosins: Matching functions with motors
5. The Pfam protein families database
6. TEDS rule: A molecular rationale for differential regulation of myosins by phosphorylation of the heavy chain head
7. Algorithms for protein structural motif recognition
8. Molecular cloning and domain structure of human myosin-VIIa, the gene product defective in Usher syndrome 1B
9. Baculovirus-mediated expression of myosin X
10. Unconventional myosins
11. The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane
12. A role for myosin-I in actin assembly through interactions with Vrp1p, Bee1p, and the Arp2/3 complex
13. A comprehensive set of sequence analysis programs for the VAX
14. Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins
15. The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells
16. Sertoli cell ectoplasmic specializations: A type of actin-associated adhesion junction?
17. Pleckstrin domain homology
18. Mapping of unconventional myosins in mouse and human
19. The growing family of myosin motors and their role in neurons and sensory cells
20. Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation
21. Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast
22. Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains
23. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
24. Cell migration: A physically integrated molecular process
25. Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization
26. PH domains: Diverse sequences with a common fold recruit signaling molecules to the cell surface
27. Requirement for the NINAC kinase/myosin for stable termination of the visual cascade
28. Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2
29. Predicting coiled coils from protein sequences
30. Structure of the pleckstrin homology domain from beta-spectrin
31. A putative modular domain present in diverse signalling proteins
32. Unconventional myosins in cell movement, membrane traffic, and signal transduction
33. Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance
34. Coronin localizes to leading edges and is involved in cell spreading and lamellipodium extension in vertebrate cells
35. Actin-based cell motility and cell locomotion
36. Unconventional myosins
37. The rat myosin myr 5 is a GTPase-activating protein for Rho in vivo: Essential role of arginine 1695
38. The PH domain: A common piece in the structural patchwork of signalling proteins
39. Tails of unconventional myosins
40. Molecular and phenotypic mapping of the short arm of chromosome 5: Sublocalization of the critical region for the cri-du-chat syndrome
41. Characterization of a second myosin from Acanthamoeba castellanii
42. AF-6/cno: Neither a kinesin nor a myosin, but a bit of both
43. Human myosin-IXb is a mechanochemically active motor and a GAP for rho
44. A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains
45. The role of phosphoinositide 3-kinase lipid products in cell function
46. PEST sequences and regulation by proteolysis
47. A novel plant calmodulin-binding protein with a kinesin heavy chain motor domain
48. Physical map and characterization of transcripts in the candidate interval for familial chondrocalcinosis at chromosome 5p15.1
49. Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase
50. A potentially exhaustive screening strategy reveals two novel divergent myosins in Dictyostelium
51. Myosins: A diverse superfamily
52. Molecular cloning of myosins from the bullfrog saccular macula: A candidate for the hair-cell adaptation motor
53. Localization of endogenous ARF6 to sites of cortical actin rearrangement and involvement of ARF6 in cell spreading
54. Identification of myosin II as a binding protein to the PH domain of protein kinase B
55. The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphate
56. Binding of G protein beta gamma-subunits to pleckstrin homology domains
57. Cortical actin organization: Lessons from ERM (ezrin/radixin/moesin) proteins
58. Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3
59. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly
60. Pleckstrin homology domains interact with filamentous actin
61. Mouse myosin X: Molecular architecture and tissue expression as revealed by northern blot and in situ hybridization analyses
62. 32P]phosphatidylinositol trisphosphate levels, alters F-actin distribution and impairs pinocytosis